D:Soft Tissue Infections

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Disease Term
Synonyms Infection Soft Tissue, Infections Soft Tissue, Soft Tissue Infection
Documents 208
Hot Single Events 18
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Soft Tissue Infections. They are ordered first by their relevance to Soft Tissue Infections and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 5.00
2 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 5.00
3 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68 5.00
4 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84 5.00
5 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 5.00
6 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69 5.00
7 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68 5.00
8 INT199497 Pdyn Negative_regulation of Il1 1 0.00 0.14 1.67 5.00
9 INT199490 Penk Positive_regulation of Oprk1 1 0.03 0.87 1.64 5.00
10 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63 5.00
11 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4 5.00
12 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38 5.00
13 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15 5.00
14 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86 5.00
15 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86 5.00
16 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86 5.00
17 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86 5.00
18 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85 5.00
19 INT199495 Il4 Positive_regulation of Positive_regulation of Oprm1 1 0.00 0.98 0.78 5.00
20 INT199476 Il4 Positive_regulation of Transcription of Stat6 1 0.01 0.97 0.77 5.00
21 INT199488 Il4 Positive_regulation of Transcription of Oprm1 1 0.01 0.84 0.73 5.00
22 INT199489 Stat6 Positive_regulation of Oprm1 1 0.02 0.85 0.68 5.00
23 INT180718 Binding of SARS and ACE2 3 0.12 7.76 0.25 5.00
24 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
25 INT180715 Binding of SARS and CLEC4M 2 0.12 2.92 0.11 5.00
26 INT250804 Binding of CCL4L1 and AP5M1 1 0.01 1.48 0.08 5.00
27 INT250801 Binding of AP5M1 and MAPKAP1 1 0.00 1.48 0.08 5.00
28 INT250802 Binding of IL6 and AP5M1 1 0.01 1.47 0.05 5.00
29 INT250803 Binding of SARS and MBL3P 1 0.09 1.7 0.04 5.00
30 INT246640 GAST Positive_regulation of NFASC 1 0.00 1.26 0.03 5.00
31 INT180164 Gast Positive_regulation of Nfasc 1 0.02 1.31 0 5.00
32 INT325904 Binding of F2 and Wbp5 1 0.01 1.22 0 5.00
33 INT325898 Negative_regulation of Binding of F2 and Gopc 1 0.03 0.14 0 5.00
34 INT325910 Wbp5 Positive_regulation of Positive_regulation of F2 1 0.01 0.67 0 5.00
35 INT325900 Binding of Dio1 and Wbp5 1 0.00 0.25 0 5.00
36 INT325902 Binding of F2 and Fgg 1 0.01 0 0 5.00
37 INT325908 Binding of Wbp5 and Fgg 1 0.00 1.2 0 5.00
38 INT325903 Binding of F2 and Gopc 1 0.02 0.26 0 5.00
39 INT325901 Binding of Dio1 and F2 1 0.01 0.63 0 5.00
40 INT325897 Negative_regulation of Binding of F2 and Wbp5 1 0.01 0.96 0 5.00
41 INT325905 Wbp5 Positive_regulation of F2 1 0.01 0.37 0 5.00
42 INT325906 Binding of Hps3 and Fgg 1 0.02 0.96 0 5.00
43 INT249364 Binding of PCS and Alb 1 0.00 0.75 0 5.00
44 INT325899 Binding of Hps3 and F2 1 0.12 2.43 0 5.00
45 INT325907 Positive_regulation of Binding of F2 and Gopc 1 0.03 0.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Soft Tissue Infections. They are ordered first by their pain relevance and then by number of times they were reported in Soft Tissue Infections. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
2 INT274806 Binding of NDST1 1 0.36 1.39 0.2 100.00
3 INT156802 Positive_regulation of Fetub 2 0.43 9.13 3.47 98.08
4 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 97.20
5 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 97.20
6 INT183910 Negative_regulation of Gene_expression of Lbp 10 0.35 9.78 6.15 97.20
7 INT206737 Negative_regulation of Gene_expression of HMGB1 3 0.32 3.48 0.09 97.20
8 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55 96.60
9 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 96.60
10 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 96.60
11 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 96.60
12 INT217431 Positive_regulation of Localization of SLC9A6 1 0.27 7.38 0.12 95.56
13 INT192975 Localization of SLC9A6 7 0.43 14.24 0.24 95.56
14 INT101922 Regulation of MICA 2 0.39 2.64 0.15 93.28
15 INT217429 Positive_regulation of SLC9A6 22 0.38 42.17 0.67 88.40
16 INT217426 Positive_regulation of Binding of SLC9A6 1 0.27 2.04 0 87.20
17 INT209355 Binding of SLC9A6 8 0.42 14.9 0.09 86.24
18 INT233 Binding of Gast 31 0.42 17.07 5.21 85.84
19 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 79.60
20 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 79.60
21 INT64175 Negative_regulation of Gene_expression of CPOX 66 0.38 39.64 23.07 79.60
22 INT30 Gene_expression of Gast 158 0.78 99 41.45 79.12
23 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 78.36
24 INT228434 Positive_regulation of MAL 2 0.04 0.81 0.05 76.64
25 INT34367 Negative_regulation of MBLAC2 2 0.43 1.21 0 76.16
26 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 76.00
27 INT213659 Gene_expression of RIT1 6 0.74 3.75 0.92 74.56
28 INT213657 Gene_expression of Fetub 1 0.41 1.9 0.74 71.52
29 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 71.24
30 INT65489 Regulation of Gene_expression of Crp 28 0.59 29.17 7.56 71.24
31 INT11101 Regulation of Gene_expression of Lbp 6 0.61 5.43 3.49 71.24
32 INT299470 Regulation of Gene_expression of HMGB1 1 0.18 1.58 0 71.24
33 INT8632 Regulation of Nfasc 15 0.54 2.87 9.08 68.76
34 INT299469 Regulation of HMGB1 2 0.18 2.27 0.03 65.88
35 INT65072 Gene_expression of TKT 16 0.65 17.58 3.55 64.56
36 INT228433 Negative_regulation of Gene_expression of TKT 2 0.35 1.13 0.32 64.56
37 INT217427 Transcription of SLC9A6 1 0.38 4.64 0 61.76
38 INT252662 Binding of SYT16 1 0.01 8.05 0.45 59.92
39 INT19511 Localization of Il6 212 0.81 118.17 67.67 56.24
40 INT1030 Localization of Lbp 52 0.74 38.92 24.91 56.24
41 INT38056 Localization of Crp 71 0.78 53.14 17.03 56.24
42 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 56.24
43 INT184288 Localization of HMGB1 20 0.61 14.5 3.84 56.24
44 INT133733 Positive_regulation of Localization of Lbp 6 0.43 9.19 3.61 56.24
45 INT219168 Positive_regulation of Localization of HMGB1 5 0.36 4 1.16 56.24
46 INT157115 Positive_regulation of Localization of Crp 4 0.59 1.96 0.88 56.24
47 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74 53.52
48 INT1148 Positive_regulation of ecs 38 0.48 25.27 13.1 50.00
49 INT297935 Positive_regulation of SUMF2 1 0.02 0.95 0 50.00
50 INT209356 Regulation of SLC9A6 2 0.39 5.61 0.14 46.08
51 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 42.96
52 INT55647 Binding of Nfasc 5 0.35 5.43 0.94 39.84
53 INT209354 Gene_expression of SLC9A6 15 0.58 37.52 0.29 37.76
54 INT213410 Localization of TKT 3 0.71 1.89 0.61 35.76
55 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 35.00
56 INT22943 Positive_regulation of Positive_regulation of Gpt 23 0.47 16.09 5.55 35.00
57 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 34.24
58 INT35103 Positive_regulation of Positive_regulation of SLC17A5 5 0.12 7.51 1.25 34.24
59 INT51262 Positive_regulation of TKT 7 0.69 4.31 0.82 33.00
60 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45 31.12
61 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 29.12
62 INT90826 Localization of NFASC 8 0.17 6.01 1.97 28.40
63 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 28.28
64 INT151978 Negative_regulation of Positive_regulation of Cys1 3 0.41 4.15 0.24 26.04
65 INT160095 Binding of DDX20 1 0.14 0.34 0 25.00
66 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 24.68
67 INT6481 Binding of TNF 624 0.48 510.2 214.82 20.40
68 INT250817 Binding of AP5M1 2 0.01 2.72 0.15 16.88
69 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 5.00
70 INT292 Localization of Penk 876 0.81 88.44 669.14 5.00
71 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 5.00
72 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
73 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 5.00
74 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
75 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
76 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
77 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 5.00
78 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 5.00
79 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 5.00
80 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
81 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
82 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 5.00
83 INT1562 Localization of Crh 499 0.81 126.74 236.68 5.00
84 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
85 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 5.00
86 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 5.00
87 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 5.00
88 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
89 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 5.00
90 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
91 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 5.00
92 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
93 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
94 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 5.00
95 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
96 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76 5.00
97 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
98 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
99 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
100 INT1438 Localization of Pomc 360 0.81 101.26 116.47 5.00
101 INT90 Localization of Gast 400 0.81 137.67 113 5.00
102 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
103 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
104 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
105 INT12569 Localization of Oprd1 94 0.81 23.81 104.56 5.00
106 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
107 INT1898 Regulation of Crh 220 0.62 61.33 102.64 5.00
108 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
109 INT4822 Localization of Ca2 417 0.80 99.57 96.45 5.00
110 INT29971 Gene_expression of Oprk1 126 0.78 35.32 93.97 5.00
111 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
112 INT18032 Positive_regulation of Oprk1 108 0.70 30.78 89.7 5.00
113 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 5.00
114 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 5.00
115 INT7028 Localization of Pdyn 90 0.81 8.89 73.54 5.00
116 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
117 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 5.00
118 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 5.00
119 INT5573 Negative_regulation of Gene_expression of Penk 113 0.59 21.83 64.66 5.00
120 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
121 INT10706 Regulation of Il6 150 0.62 93.23 62.34 5.00
122 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
123 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
124 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 5.00
125 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65 5.00
126 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
127 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
128 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54 5.00
129 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
130 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 5.00
131 INT10668 Positive_regulation of Gene_expression of Oprd1 61 0.69 15.21 52.12 5.00
132 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 5.00
133 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21 5.00
134 INT19775 Localization of Il1 183 0.78 145.5 50.91 5.00
135 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
136 INT22454 Regulation of Crp 213 0.62 160.67 49.24 5.00
137 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 5.00
138 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
139 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
140 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23 5.00
141 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 5.00
142 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
143 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
144 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 5.00
145 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
146 INT20210 Localization of Ngf 69 0.79 46.22 38.57 5.00
147 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
148 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
149 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
150 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 5.00
151 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 5.00
152 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
153 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
154 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 5.00
155 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 5.00
156 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66 5.00
157 INT91 Positive_regulation of Localization of Gast 96 0.70 23.22 29.36 5.00
158 INT15000 Transcription of Oprd1 32 0.72 5.7 29.22 5.00
159 INT10799 Localization of ENG 63 0.78 18.67 27.28 5.00
160 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
161 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
162 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 5.00
163 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
164 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34 5.00
165 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11 5.00
166 INT20129 Regulation of Il1 53 0.53 44.14 19.89 5.00
167 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
168 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 5.00
169 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
170 INT52179 Regulation of Lbp 39 0.61 25.4 18.32 5.00
171 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 5.00
172 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 5.00
173 INT106745 Localization of CRP 65 0.81 66.44 15.21 5.00
174 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 5.00
175 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 5.00
176 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 5.00
177 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
178 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
179 INT71510 Positive_regulation of Selp 47 0.68 30.43 12.8 5.00
180 INT32595 Positive_regulation of Gene_expression of Il2 30 0.70 6.55 12.56 5.00
181 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 5.00
182 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
183 INT99587 Positive_regulation of Gene_expression of Oprk1 15 0.57 5.26 12.39 5.00
184 INT21160 Gene_expression of Sell 28 0.64 19.37 12.18 5.00
185 INT4047 Binding of F13A1 105 0.43 66.54 11.81 5.00
186 INT82684 Positive_regulation of Pecam1 27 0.49 25.67 11.47 5.00
187 INT37390 Regulation of Crp 39 0.46 28.74 11.45 5.00
188 INT90903 Positive_regulation of Positive_regulation of Oprk1 13 0.47 3.49 11.18 5.00
189 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 5.00
190 INT30438 Negative_regulation of Gene_expression of Pdyn 8 0.57 1.15 10.46 5.00
191 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23 5.00
192 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68 5.00
193 INT180163 Positive_regulation of Nfasc 49 0.40 31.96 9.41 5.00
194 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 5.00
195 INT82685 Gene_expression of Pecam1 36 0.76 27.95 9.01 5.00
196 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
197 INT23147 Negative_regulation of MRI1 26 0.38 14.33 8.96 5.00
198 INT860 Regulation of ALB 48 0.60 25.11 8.95 5.00
199 INT69528 Regulation of Gene_expression of Oprk1 10 0.45 4.27 8.84 5.00
200 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61 5.00
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