D:Soft Tissue Injuries

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms INJURIES SOFT TISSUE, Injury Soft Tissue, Soft Tissue Injury
Documents 327
Hot Single Events 37
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Soft Tissue Injuries. They are ordered first by their relevance to Soft Tissue Injuries and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47 76.64
2 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47 76.64
3 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96 7.64
4 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14 5.00
5 INT202974 Binding of BAG3 and CPP 1 0.25 6.22 2.73 5.00
6 INT202963 Binding of STC2 and CPP 1 0.02 5.16 2.04 5.00
7 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44 5.00
8 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13 5.00
9 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08 5.00
10 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73 5.00
11 INT202962 CPP Negative_regulation of Positive_regulation of BAG3 1 0.26 1.34 0.61 5.00
12 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59 5.00
13 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58 5.00
14 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58 5.00
15 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57 5.00
16 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57 5.00
17 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51 5.00
18 INT244299 FFAR1 Positive_regulation of PTH1R 1 0.00 0.4 0.2 5.00
19 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15 5.00
20 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15 5.00
21 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15 5.00
22 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1 5.00
23 INT206619 Mtpn Positive_regulation of Igf1 1 0.04 0.17 0.05 5.00
24 INT206620 Gh1 Positive_regulation of Igf1 1 0.25 0.17 0.04 5.00
25 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0 5.00
26 INT206621 Col1a1 Positive_regulation of Col3a1 1 0.00 0.28 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Soft Tissue Injuries. They are ordered first by their pain relevance and then by number of times they were reported in Soft Tissue Injuries. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1 99.52
2 INT202975 Regulation of Regulation of STC2 1 0.01 1.08 0.36 98.78
3 INT162254 Regulation of BAG3 28 0.41 18.12 4.75 98.58
4 INT202983 Regulation of STC2 1 0.03 11.98 3.33 98.44
5 INT121106 Binding of Slmap 10 0.37 5.19 3.71 97.00
6 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 95.52
7 INT72024 Localization of EDNRA 11 0.57 8.22 0.96 95.32
8 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 94.08
9 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69 94.00
10 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25 94.00
11 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 93.88
12 INT15470 Regulation of CPP 42 0.48 26.1 18.25 93.56
13 INT74879 Regulation of MPG 6 0.44 0.8 1.08 93.44
14 INT202978 Gene_expression of STC2 11 0.50 13.46 4.06 92.64
15 INT58109 Positive_regulation of Positive_regulation of MPG 2 0.49 0.37 1.42 92.48
16 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 92.32
17 INT162253 Gene_expression of BAG3 30 0.59 20.16 7.18 92.24
18 INT19538 Positive_regulation of MPG 8 0.67 3.21 3.57 91.56
19 INT160280 Positive_regulation of ipv 14 0.44 15.73 1.02 90.56
20 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 89.92
21 INT226471 Negative_regulation of ST2 3 0.11 1.88 0.28 89.52
22 INT30039 Negative_regulation of HAL 7 0.42 4.32 1.61 87.84
23 INT143664 Gene_expression of ST2 9 0.77 5.03 1.73 86.44
24 INT143665 Positive_regulation of Gene_expression of ST2 1 0.69 0.7 0.04 86.44
25 INT97912 Gene_expression of Sod3 25 0.78 22.44 3.28 85.92
26 INT97910 Positive_regulation of Gene_expression of Sod3 13 0.70 15.56 2.46 85.92
27 INT103463 Localization of CPP 16 0.66 9.63 4.08 85.20
28 INT159673 Positive_regulation of Localization of CPP 4 0.41 3.43 1.34 85.20
29 INT85233 Localization of SGSM3 11 0.78 10.91 3.41 84.88
30 INT98660 Positive_regulation of Localization of SGSM3 2 0.45 1.67 0.62 84.88
31 INT157797 Negative_regulation of Phosphorylation of Smad3 3 0.40 0.95 0.17 84.56
32 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 83.92
33 INT97216 Positive_regulation of Psd 13 0.45 7.04 1.25 83.28
34 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 81.80
35 INT157804 Phosphorylation of Smad3 18 0.77 8.15 0.35 81.16
36 INT969 Negative_regulation of FASTK 5 0.38 4.03 1.14 80.96
37 INT93309 Positive_regulation of CAP1 17 0.43 11.4 9.13 80.56
38 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 79.72
39 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 79.12
40 INT184716 Binding of Smad7 2 0.34 0.91 0.29 78.24
41 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 78.16
42 INT201967 Positive_regulation of Bmpr2 4 0.31 1.24 0.34 75.24
43 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55 75.04
44 INT172592 Positive_regulation of PTH1R 9 0.28 6.25 2.5 74.28
45 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44 72.96
46 INT184894 Localization of MCRS1 9 0.47 10.04 3.31 72.80
47 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0 70.36
48 INT114714 Binding of IGF1R 8 0.36 5.26 0.78 70.24
49 INT85808 Localization of BMP2 7 0.77 1.94 0.51 70.12
50 INT1221 Regulation of SGCG 65 0.60 24.21 22.94 67.60
51 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02 64.04
52 INT92589 Positive_regulation of IGF1R 4 0.38 0.98 0.11 60.16
53 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 54.16
54 INT8916 Regulation of Igf1 45 0.60 13.06 5.81 54.08
55 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 52.32
56 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07 51.96
57 INT181986 Negative_regulation of Positive_regulation of Col7a1 6 0.08 7.4 2.46 50.64
58 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51 50.48
59 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44 50.12
60 INT234 Binding of Alb 151 0.48 52.34 32.97 50.00
61 INT65119 Negative_regulation of Des 4 0.41 1.29 2.14 50.00
62 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49 49.76
63 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 48.96
64 INT166131 Positive_regulation of Positive_regulation of Col7a1 8 0.46 6.4 1.65 48.96
65 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 47.88
66 INT193281 Binding of CAP1 7 0.07 4.57 3.53 46.56
67 INT244300 Localization of PTH1R 2 0.74 2.03 0.67 46.16
68 INT77818 Positive_regulation of EMG1 24 0.54 2.73 1.59 42.04
69 INT108913 Positive_regulation of HAL 10 0.28 5.71 1.59 36.88
70 INT219929 Positive_regulation of Gene_expression of Bmpr2 3 0.15 0.9 0 32.76
71 INT111533 Positive_regulation of Gene_expression of Nfkb1 27 0.52 17.32 7.89 28.96
72 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 28.44
73 INT143666 Positive_regulation of ST2 15 0.69 11.76 0.85 28.40
74 INT175828 Regulation of FASTK 1 0.24 1.48 0.11 27.04
75 INT176317 Transcription of CAP1 3 0.16 1.8 1.15 26.24
76 INT201962 Transcription of Bmpr2 6 0.37 3.51 0.09 20.12
77 INT168479 Binding of BAG3 13 0.36 10.68 4.21 19.28
78 INT202977 Binding of STC2 1 0.02 8.53 3.31 18.56
79 INT47909 Binding of CPP 32 0.48 24.9 13.79 18.00
80 INT175554 Binding of MCRS1 21 0.23 25.2 8.59 17.60
81 INT195817 Gene_expression of ipv 28 0.58 31.04 1.86 10.44
82 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 7.20
83 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 6.88
84 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 5.48
85 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
86 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
87 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
88 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 5.00
89 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
90 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
91 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
92 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 5.00
93 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
94 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
95 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
96 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 5.00
97 INT10166 Localization of Tnf 237 0.81 153.95 88.64 5.00
98 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 5.00
99 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
100 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 5.00
101 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
102 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
103 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
104 INT9664 Binding of LBP 127 0.48 94.9 63.42 5.00
105 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
106 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
107 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
108 INT1782 Regulation of Gh1 125 0.62 22 55.74 5.00
109 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 5.00
110 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34 5.00
111 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 5.00
112 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
113 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 5.00
114 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 5.00
115 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
116 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
117 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
118 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 5.00
119 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
120 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 5.00
121 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 5.00
122 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
123 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 5.00
124 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 5.00
125 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
126 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
127 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23 5.00
128 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 5.00
129 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 5.00
130 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
131 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 5.00
132 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
133 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 5.00
134 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76 5.00
135 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
136 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 5.00
137 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89 5.00
138 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
139 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
140 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39 5.00
141 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03 5.00
142 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 5.00
143 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
144 INT91648 Binding of SPECC1 7 0.48 22.42 19.36 5.00
145 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 5.00
146 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 5.00
147 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
148 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 5.00
149 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61 5.00
150 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 5.00
151 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46 5.00
152 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
153 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1 5.00
154 INT10173 Binding of Tnf 45 0.48 35.6 14.32 5.00
155 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 5.00
156 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 5.00
157 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
158 INT10654 Negative_regulation of SGSM3 31 0.57 12.24 11.7 5.00
159 INT25613 Gene_expression of Il1f5 32 0.77 13.29 10.44 5.00
160 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 5.00
161 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25 5.00
162 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15 5.00
163 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14 5.00
164 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85 5.00
165 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
166 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98 5.00
167 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 5.00
168 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 5.00
169 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 5.00
170 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
171 INT39457 Positive_regulation of SOAT1 32 0.67 22.8 8.28 5.00
172 INT134106 Positive_regulation of SPECC1 14 0.68 9.44 8.09 5.00
173 INT4299 Positive_regulation of Gene_expression of Gh1 27 0.50 5.24 7.31 5.00
174 INT91509 Localization of CYC1 39 0.78 34.74 7.17 5.00
175 INT878 Regulation of Gene_expression of Gh1 13 0.43 1.13 6.98 5.00
176 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
177 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42 5.00
178 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26 5.00
179 INT91217 Positive_regulation of BAG3 22 0.48 16.57 6.06 5.00
180 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 5.00
181 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 5.00
182 INT3614 Negative_regulation of Gene_expression of Gh1 16 0.42 6.8 5.74 5.00
183 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7 5.00
184 INT9325 Gene_expression of Igf1r 14 0.77 8.74 5.48 5.00
185 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46 5.00
186 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45 5.00
187 INT95120 Positive_regulation of CASP9 76 0.67 67.55 5.33 5.00
188 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25 5.00
189 INT6476 Gene_expression of TNFRSF1B 21 0.67 18.22 5.25 5.00
190 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 5.00
191 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
192 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87 5.00
193 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77 5.00
194 INT75530 Regulation of SGSM3 11 0.60 7.22 4.48 5.00
195 INT33071 Negative_regulation of Gene_expression of Gnrhr 13 0.53 5.99 4.41 5.00
196 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26 5.00
197 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09 5.00
198 INT126477 Gene_expression of Sdf2l1 43 0.66 22.02 3.97 5.00
199 INT202976 Positive_regulation of STC2 1 0.04 9.73 3.78 5.00
200 INT160828 Regulation of Gene_expression of Ros1 29 0.21 13.97 3.75 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox