D:Spinal Curvatures

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pChart

Disease Term
Synonyms Curvature Spinal, Curvatures Spinal, Spinal Curvature
Documents 78
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Spinal Curvatures. They are ordered first by their relevance to Spinal Curvatures and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT239573 Binding of DPF1 and AIS 1 0.02 0.74 0.31 5.00
2 INT239570 Binding of PDGFC and AIS 1 0.04 0.9 0.26 5.00
3 INT239572 DPF1 Positive_regulation of AIS 1 0.02 0.71 0.24 5.00
4 INT239571 Binding of PDGFC and IGSF10 1 0.00 0.34 0.08 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Spinal Curvatures. They are ordered first by their pain relevance and then by number of times they were reported in Spinal Curvatures. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 94.56
2 INT257560 Regulation of Negative_regulation of JAG1 1 0.13 0.48 0 85.64
3 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5 85.20
4 INT138594 Gene_expression of COP 10 0.57 1.33 0.98 80.60
5 INT288238 Gene_expression of IGKV2-14 1 0.22 0.18 0 67.32
6 INT74781 Regulation of JAG1 6 0.39 2.75 0.63 64.24
7 INT38672 Binding of KRT20 69 0.39 48.01 6.31 60.84
8 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 51.44
9 INT147584 Localization of AIS 38 0.63 12.83 5.27 48.60
10 INT148564 Localization of HAL 8 0.68 2.46 0.62 7.28
11 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
12 INT920 Localization of PLOD1 223 0.81 42.25 78.7 5.00
13 INT654 Localization of REN 250 0.81 75.12 47.86 5.00
14 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 5.00
15 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
16 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 5.00
17 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 5.00
18 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 5.00
19 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
20 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 5.00
21 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 5.00
22 INT912 Localization of FSHR 91 0.79 23.61 15.58 5.00
23 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25 5.00
24 INT38564 Binding of AIS 36 0.38 27.77 9.31 5.00
25 INT191765 Regulation of CALM1 15 0.52 9.52 8.56 5.00
26 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 5.00
27 INT55091 Positive_regulation of Mgst1 35 0.69 10.77 6.88 5.00
28 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 5.00
29 INT44608 Gene_expression of C2 45 0.75 15.84 5.05 5.00
30 INT923 Positive_regulation of Localization of FSHR 14 0.43 2.48 4.96 5.00
31 INT38698 Positive_regulation of COP 9 0.59 2.05 4.48 5.00
32 INT49633 Positive_regulation of NBL1 9 0.37 0.38 4.13 5.00
33 INT33951 Regulation of TXNRD1 18 0.51 6.97 4.02 5.00
34 INT171998 Binding of DMD 58 0.47 38.13 3.35 5.00
35 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12 5.00
36 INT93109 Phosphorylation of NTRK1 5 0.80 3.22 2.99 5.00
37 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 5.00
38 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41 5.00
39 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 5.00
40 INT59790 Binding of BCR 16 0.36 15.34 1.75 5.00
41 INT30039 Negative_regulation of HAL 7 0.42 4.32 1.61 5.00
42 INT108913 Positive_regulation of HAL 10 0.28 5.71 1.59 5.00
43 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52 5.00
44 INT50010 Negative_regulation of CHR 5 0.42 3.64 1.41 5.00
45 INT239575 Regulation of PDGFC 1 0.07 4.93 1.3 5.00
46 INT116524 Regulation of COP 5 0.35 0.63 1.25 5.00
47 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 5.00
48 INT171057 Gene_expression of PDGFC 7 0.15 5.84 1.22 5.00
49 INT171433 Gene_expression of AIC 7 0.59 3.06 1.11 5.00
50 INT80338 Gene_expression of SPTLC1 10 0.78 4.06 1.09 5.00
51 INT182645 Localization of C2 6 0.74 3.02 1.08 5.00
52 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 5.00
53 INT189130 Regulation of AIS 11 0.39 7.64 0.99 5.00
54 INT86273 Gene_expression of NBL1 10 0.71 2.92 0.98 5.00
55 INT30041 Binding of HAL 8 0.35 2.36 0.95 5.00
56 INT17807 Positive_regulation of PDGFC 4 0.06 3.28 0.86 5.00
57 INT239574 Binding of PDGFC 1 0.04 3.29 0.79 5.00
58 INT116763 Gene_expression of IKBKAP 63 0.78 54.53 0.79 5.00
59 INT148382 Positive_regulation of JAG1 5 0.23 3.88 0.63 5.00
60 INT37351 Negative_regulation of IKBKAP 16 0.58 9.6 0.56 5.00
61 INT239577 Gene_expression of GLIPR1 1 0.03 2.34 0.5 5.00
62 INT294953 Negative_regulation of PPYR1 1 0.03 0.63 0.48 5.00
63 INT149861 Gene_expression of CD52 14 0.75 9.35 0.47 5.00
64 INT193576 Positive_regulation of Gene_expression of AIS 4 0.39 1.94 0.46 5.00
65 INT217067 Regulation of Positive_regulation of MAPK8 7 0.45 3.09 0.43 5.00
66 INT230619 Gene_expression of EN2 3 0.65 0.15 0.41 5.00
67 INT94146 Regulation of SPTLC1 2 0.51 2.39 0.36 5.00
68 INT239068 Regulation of SEA 3 0.07 1.37 0.31 5.00
69 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 5.00
70 INT239579 Negative_regulation of GLC2A 1 0.02 0.85 0.15 5.00
71 INT239580 Regulation of GLIPR1 1 0.01 0.61 0.15 5.00
72 INT257559 Localization of AIC 3 0.69 1.43 0.12 5.00
73 INT192085 Gene_expression of Atr 5 0.47 0.38 0.11 5.00
74 INT239581 Positive_regulation of MYH16 1 0.46 0.25 0.1 5.00
75 INT217951 Gene_expression of MYH16 3 0.62 0.25 0.1 5.00
76 INT84653 Gene_expression of DPF1 2 0.30 1.3 0.1 5.00
77 INT200089 Binding of CATR1 1 0.35 0.75 0.05 5.00
78 INT239578 Positive_regulation of Gene_expression of CD52 2 0.16 1.37 0.03 5.00
79 INT239576 Regulation of Localization of AIS 1 0.35 0.65 0.03 5.00
80 INT294954 Regulation of Gene_expression of EN2 1 0.44 0.07 0.03 5.00
81 INT296197 Regulation of D7Cwr3P 1 0.01 0 0 5.00
82 INT192391 Gene_expression of Yes1 4 0.32 1.64 0 5.00
83 INT288289 Positive_regulation of Cm3 3 0.09 0.74 0 5.00
84 INT296196 Negative_regulation of Positive_regulation of Cm3 1 0.03 0.17 0 5.00
85 INT294955 Protein_catabolism of ASPN 1 0.05 0.07 0 5.00
86 INT180621 Negative_regulation of Gene_expression of HAL 1 0.05 0 0 5.00
87 INT150716 Localization of COP 5 0.48 1.36 0 5.00
88 INT239582 Gene_expression of LHX2 1 0.03 0.39 0 5.00
89 INT222215 Positive_regulation of Gene_expression of Yes1 1 0.20 0.68 0 5.00
90 INT180620 Positive_regulation of Positive_regulation of HAL 1 0.06 0.09 0 5.00
91 INT288239 Negative_regulation of IGKV2-14 1 0.12 0.16 0 5.00
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