D:Spinocerebellar Ataxia Type 2

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Disease Term
Synonyms Ataxia Dominantly Inherited Spinocerebellar, Ataxia Spinocerebellar, Ataxias Dominantly Inherited Spinocerebellar, Ataxias Spinocerebellar, Atrophies Spinocerebellar, Atrophy Spinocerebellar, Dominantly Inherited Spinocerebellar Ataxia, Dominantly Inherited Spinocerebellar Ataxias, SPINOCEREBELLAR ATAXIA, SPINOCEREBELLAR ATAXIA 1, Spinocerebellar Ataxia 2
Documents 97
Hot Single Events 121
Hot Interactions 17

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Spinocerebellar Ataxia Type 2. They are ordered first by their relevance to Spinocerebellar Ataxia Type 2 and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55 100.00
2 INT142004 Binding of Cacna1a and TGM6 1 0.00 1.02 0.26 100.00
3 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36 100.00
4 INT101551 Binding of CACNA1A and CACNA1F 1 0.07 1.51 0.33 100.00
5 INT142003 Binding of Cacna1a and Etax2 1 0.00 1.02 0.26 99.88
6 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27 99.40
7 INT245039 Binding of Xrcc1 and Tdp1 1 0.39 0.77 0 97.96
8 INT245041 Binding of Xrcc1 and APTX 1 0.41 0.38 0 96.28
9 INT155752 Binding of CACNA1A and ATCAY 1 0.04 0.86 0.42 91.28
10 INT208554 Phosphorylation of YWHAQ Positive_regulation of Binding of YWHAQ and Akt1 1 0.32 1.04 0.08 88.04
11 INT208556 Binding of YWHAQ and Akt1 1 0.22 1.02 0.08 86.64
12 INT208555 YWHAQ Positive_regulation of Atxn1 1 0.77 1.02 0.08 86.16
13 INT71329 Cacna1a Regulation of Ea2 1 0.01 0.71 0.15 85.36
14 INT277318 Upf1 Positive_regulation of Atxn8os 1 0.01 0.77 0.21 84.96
15 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15 84.96
16 INT275461 Binding of Atxn1 and Atxn2 1 0.39 1.1 0.17 82.48
17 INT215342 Binding of Cebpg and Tbp 1 0.00 0.55 0 80.92
18 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21 75.00
19 INT277316 Upf1 Positive_regulation of Slc6a11 1 0.01 0.47 0.09 75.00
20 INT277320 Upf1 Positive_regulation of Upf1 Positive_regulation of Slc6a11 1 0.00 0.47 0.09 75.00
21 INT277317 Binding of Celf1 and Slc6a11 1 0.19 0.06 0.26 50.00
22 INT277319 Gene_expression of Celf1 Positive_regulation of Positive_regulation of Slc6a11 1 0.24 0.08 0.08 50.00
23 INT277313 Negative_regulation of Mbnl1 Positive_regulation of Positive_regulation of Slc6a11 1 0.52 0.08 0.08 50.00
24 INT277315 Binding of Insr and Mbnl1 1 0.18 1.1 0 50.00
25 INT277311 Mbnl1 Regulation of Gene_expression of Slc6a11 1 0.50 0.06 0 50.00
26 INT277312 Regulation of Binding of Upf1 and Mbnl1 1 0.01 0.36 0 50.00
27 INT277309 Binding of Upf1 and Mbnl1 1 0.01 0.71 0 50.00
28 INT277308 Upf1 Regulation of Regulation of Celf1 1 0.00 1.05 0 50.00
29 INT277314 Celf1 Regulation of Gene_expression of Slc6a11 1 0.23 0.06 0 50.00
30 INT277310 Binding of Tnnt2 and Mbnl1 1 0.18 1.1 0 50.00
31 INT298858 Positive_regulation of Binding of VAPA and RILP 1 0.07 0.54 0 43.60
32 INT298847 Binding of VAPA and RILP 1 0.05 0.54 0 43.60
33 INT215341 Binding of Htt and Sp1 1 0.03 0.25 0 42.44
34 INT235169 Gene_expression of Dnaja1 Negative_regulation of Binding of Atxn1 1 0.09 0.47 0 29.96
35 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22 26.68
36 INT298845 VAPA Regulation of Negative_regulation of RAB7A 1 0.12 0.32 0 23.84
37 INT298864 VAPB Regulation of Negative_regulation of RAB7A 1 0.32 0.32 0 23.84
38 INT235166 Binding of Hdac3 and Atxn1 1 0.02 0.28 0 10.52
39 INT235164 Binding of Atxn1 and Ncor2 1 0.15 0.42 0 10.52
40 INT235167 Binding of Hdac3 and Ncor2 1 0.01 0.28 0 10.16
41 INT279828 Binding of Scn1a and Scn9a 1 0.39 1.64 0.26 5.00
42 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21 5.00
43 INT279829 Scn1a Regulation of Gene_expression of Scn9a 1 0.42 1.52 0.15 5.00
44 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
45 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
46 INT309511 Binding of Xrcc6 and Xrcc5 1 0.18 1.18 0.08 5.00
47 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05 5.00
48 INT190044 Binding of Msh2 and Msh6 2 0.32 0.77 0.05 5.00
49 INT190050 Binding of Msh2 and Pms2 2 0.32 0.49 0.04 5.00
50 INT254909 ARSH Regulation of Sumf1 1 0.00 0.9 0.04 5.00
51 INT254908 ARSH Regulation of Eef1a1 1 0.00 0.89 0.04 5.00
52 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04 5.00
53 INT190046 Binding of Msh3 and Pms2 2 0.25 0.5 0.04 5.00
54 INT298831 Binding of MTOR and RAB7A Positive_regulation of MTOR 1 0.02 0.35 0.03 5.00
55 INT298878 Binding of MTOR and RAB7A 1 0.07 0.35 0.03 5.00
56 INT235168 Binding of Crx and Atxn7 1 0.11 0.81 0.03 5.00
57 INT298872 RAB7A Regulation of Protein_catabolism of GFM1 1 0.47 0.22 0.03 5.00
58 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
59 INT298873 RAB7A Regulation of Protein_catabolism of NTRK1 1 0.12 0.25 0.03 5.00
60 INT298854 Binding of LAMP2 and RAB7A 1 0.16 0.56 0 5.00
61 INT298862 Binding of MCC and VPS13C 1 0.00 0.36 0 5.00
62 INT298879 Binding of MCC and MTG1 1 0.00 0.37 0 5.00
63 INT331234 Binding of Becn1 and Pik3c3 Positive_regulation of Pik3c3 1 0.00 0.47 0 5.00
64 INT331226 Binding of Becn1 and Pik3c3 1 0.02 0.47 0 5.00
65 INT298863 Binding of VAPB and RILP 1 0.13 0.21 0 5.00
66 INT331238 Binding of ULK1 and Pik3r1 1 0.09 0.48 0 5.00
67 INT331237 Negative_regulation of IMPA1 Negative_regulation of Itpr3 1 0.00 0.52 0 5.00
68 INT330697 PCNA Regulation of INCENP 1 0.00 0.3 0 5.00
69 INT331232 Binding of Atg12 and Atg16l1 1 0.03 0.08 0 5.00
70 INT215349 Binding of VDAC1 and Tspo 1 0.00 0.63 0 5.00
71 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0 5.00
72 INT298875 Binding of RAB7A and VPS13C 1 0.21 0.49 0 5.00
73 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0 5.00
74 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0 5.00
75 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0 5.00
76 INT298868 Binding of RAB7A and GOPC 1 0.07 1.64 0 5.00
77 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0 5.00
78 INT215345 Positive_regulation of Binding of Srebf1 and Tbp 1 0.05 0.16 0 5.00
79 INT298848 Binding of SPG21 and RILP 1 0.10 0.21 0 5.00
80 INT331225 Binding of Atg5 and Atg16l1 1 0.05 0.08 0 5.00
81 INT331231 Binding of Bcl2 and Mapk8 1 0.01 0.77 0 5.00
82 INT298849 Binding of APOB and MCC 1 0.00 0.38 0 5.00
83 INT254906 Binding of Igfals and Chmp2b 1 0.02 0.85 0 5.00
84 INT298859 Positive_regulation of Binding of MCC and VPS13C 1 0.01 0.36 0 5.00
85 INT330696 Phosphorylation of RB1 Positive_regulation of Gene_expression of E2F2 1 0.01 1 0 5.00
86 INT309521 PRKDC Regulation of Gene_expression of Htt 1 0.41 0.08 0 5.00
87 INT215343 Binding of Srebf1 and Tbp 1 0.04 0.16 0 5.00
88 INT298853 Binding of AGFG1 and RILP 1 0.02 0.21 0 5.00
89 INT331230 Binding of Mapk8 and Becn1 1 0.02 0.77 0 5.00
90 INT298856 Binding of APOB and MTG1 1 0.00 0.38 0 5.00
91 INT298866 Binding of AGFG1 and RAB7A 1 0.04 0.21 0 5.00
92 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0 5.00
93 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0 5.00
94 INT235165 Atxn3 Regulation of Transcription of Crebbp 1 0.02 0.3 0 5.00
95 INT331228 Atg5 Positive_regulation of Atg12 1 0.06 0.08 0 5.00
96 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0 5.00
97 INT239407 Binding of MTTP and PADI1 1 0.23 0.5 0 5.00
98 INT309512 Negative_regulation of Xrcc6 Positive_regulation of Phosphorylation of Gopc 1 0.20 0.17 0 5.00
99 INT298846 Binding of MCC and RILP 1 0.01 0.36 0 5.00
100 INT331224 Binding of Akt1 and Tsc2 1 0.03 0.33 0 5.00
101 INT215344 Binding of Sp1 and Vdac1 1 0.02 0.1 0 5.00
102 INT298850 Binding of RAB7A and MTG1 1 0.01 0.24 0 5.00
103 INT298877 Positive_regulation of Binding of RAB7A and VPS13C 1 0.22 0.49 0 5.00
104 INT308030 Binding of Mpz and ASPM 1 0.02 0.55 0 5.00
105 INT331223 Negative_regulation of Tsc1 Positive_regulation of Positive_regulation of Mtor 1 0.01 0.33 0 5.00
106 INT298851 Binding of IK and RAB7A 1 0.02 0.57 0 5.00
107 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0 5.00
108 INT309518 Negative_regulation of Binding of Bax and Xrcc6 1 0.16 0.25 0 5.00
109 INT298871 ALOX5AP Positive_regulation of RAB7A 1 0.09 0.35 0 5.00
110 INT298869 Binding of RAB7A and RILP 1 0.25 1.07 0 5.00
111 INT298857 Binding of RILP and MTG1 1 0.01 0.35 0 5.00
112 INT309520 Htt Negative_regulation of Binding of Xrcc6 and Xrcc5 1 0.15 0.47 0 5.00
113 INT298855 Positive_regulation of Binding of MCC and MTG1 1 0.00 0.37 0 5.00
114 INT309516 Htt Positive_regulation of Gene_expression of Xrcc6 1 0.49 0.06 0 5.00
115 INT309509 Negative_regulation of Binding of Xrcc6 and Htt 1 0.31 0.41 0 5.00
116 INT331229 Rasa1 Positive_regulation of Mtor 1 0.00 0.32 0 5.00
117 INT331233 Binding of Mtor and Rasa1 1 0.00 0.32 0 5.00
118 INT309510 Htt Regulation of Gene_expression of Xrcc6 1 0.19 0.15 0 5.00
119 INT331236 Binding of RASA1 and Mtor 1 0.00 0.32 0 5.00
120 INT308029 ASPM Positive_regulation of Regulation of Mpz 1 0.02 0.55 0 5.00
121 INT298865 Positive_regulation of Binding of RILP and MTG1 1 0.01 0.35 0 5.00
122 INT309508 Htt Negative_regulation of Binding of Xrcc6 1 0.31 0.48 0 5.00
123 INT298852 Binding of AGFG1 and MTG1 1 0.00 0 0 5.00
124 INT349355 CSF2 Negative_regulation of CSTA 1 0.01 1.43 0 5.00
125 INT298861 Binding of APOB and RAB7A 1 0.00 0.32 0 5.00
126 INT298870 Binding of PDB1 and RAB7A 1 0.51 0.21 0 5.00
127 INT309514 Positive_regulation of Binding of Xrcc6 and Htt 1 0.33 0 0 5.00
128 INT331221 Binding of Akt1 and Tsc1 1 0.03 0.33 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Spinocerebellar Ataxia Type 2. They are ordered first by their pain relevance and then by number of times they were reported in Spinocerebellar Ataxia Type 2. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181809 Gene_expression of Atxn1 81 0.77 28.66 1.42 100.00
2 INT181803 Binding of Atxn1 12 0.48 7 0.3 100.00
3 INT235138 Gene_expression of Atxn8os 2 0.76 6.89 1.05 100.00
4 INT235157 Gene_expression of Atxn2 3 0.68 6.74 1.23 100.00
5 INT123903 Gene_expression of ATXN3 7 0.75 6.71 1.85 100.00
6 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36 100.00
7 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32 100.00
8 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1 100.00
9 INT78316 Regulation of TGM6 3 0.16 3.09 0.95 100.00
10 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43 100.00
11 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35 100.00
12 INT208543 Regulation of Icmt 1 0.59 1.64 0 100.00
13 INT181805 Transcription of Atxn1 4 0.69 1.78 0.06 100.00
14 INT181813 Negative_regulation of Gene_expression of Atxn1 9 0.42 3.47 0.15 100.00
15 INT78317 Regulation of CACNA1A 8 0.62 7.68 3.08 100.00
16 INT99456 Gene_expression of SIRT6 1 0.00 0.72 0.13 100.00
17 INT275455 Negative_regulation of Gene_expression of Atxn2 1 0.43 1.07 0.1 100.00
18 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55 100.00
19 INT277280 Gene_expression of Zfp423 1 0.75 0.27 0.03 100.00
20 INT277272 Gene_expression of Epha8 1 0.01 0.27 0.03 100.00
21 INT275454 Positive_regulation of Atxn2 1 0.50 1.37 0.53 100.00
22 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55 100.00
23 INT189811 Negative_regulation of ATXN3 1 0.35 3.09 0 100.00
24 INT99962 Positive_regulation of Gene_expression of Cacna1a 1 0.01 1.1 0.34 99.96
25 INT208544 Negative_regulation of Regulation of Icmt 1 0.41 0.48 0 99.96
26 INT189809 Negative_regulation of HEXA 1 0.57 3.93 0 99.86
27 INT277289 Transcription of Atxn8os 1 0.68 3.3 0.26 99.76
28 INT277282 Positive_regulation of Transcription of Atxn8os 1 0.49 0.54 0.14 99.76
29 INT143886 Positive_regulation of SIRT6 1 0.00 0.17 0.25 99.76
30 INT166753 Gene_expression of Cacna2d1 2 0.21 1.41 0.25 99.72
31 INT208545 Transcription of Icmt 1 0.68 3.71 0.06 99.52
32 INT90741 Binding of Ea2 1 0.05 0.48 0.28 99.48
33 INT208551 Gene_expression of Mutyh 6 0.48 6.28 0.12 99.26
34 INT99545 Positive_regulation of Ea2 4 0.24 2.42 1.4 99.14
35 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02 98.68
36 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 98.46
37 INT225981 Binding of Xrcc1 3 0.36 0.81 0 98.40
38 INT208549 Gene_expression of Icmt 5 0.74 4.67 0.1 97.96
39 INT277264 Positive_regulation of Gene_expression of Atxn8os 1 0.68 0.91 0.26 97.96
40 INT131964 Positive_regulation of CACNA1A 5 0.61 0.73 0.85 97.74
41 INT115695 Positive_regulation of ATXN1 2 0.22 1.23 0.98 97.52
42 INT103336 Transcription of Cacna1a 2 0.69 1.17 0.68 97.52
43 INT460 Negative_regulation of Atxn2 4 0.43 0.85 1.21 97.48
44 INT33466 Negative_regulation of C4B 14 0.43 9.06 4.64 97.48
45 INT23620 Negative_regulation of C4A 24 0.57 15.1 2.23 97.48
46 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87 97.28
47 INT277271 Gene_expression of Pqbp1 1 0.05 1.57 0.24 97.28
48 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37 97.16
49 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 96.48
50 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 96.48
51 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7 96.44
52 INT272475 Regulation of Mbnl1 15 0.61 5.39 0.56 95.76
53 INT75299 Binding of Atxn3 8 0.43 5.3 0.26 95.68
54 INT235130 Localization of Atxn3 4 0.75 2.91 0.03 95.36
55 INT66076 Positive_regulation of Etax2 3 0.00 3.34 1.79 94.88
56 INT158837 Binding of POLG 4 0.37 4.69 0.44 94.32
57 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 93.88
58 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81 93.84
59 INT64815 Binding of Jun 49 0.48 21.47 8.59 93.84
60 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73 93.84
61 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 93.76
62 INT208552 Negative_regulation of Negative_regulation of Gsk3b 3 0.31 1.8 0.43 93.76
63 INT85571 Positive_regulation of Cacna1a 3 0.50 2.06 1.18 92.72
64 INT208540 Positive_regulation of Icmt 2 0.66 5.15 0.12 92.52
65 INT208550 Positive_regulation of Transcription of Icmt 1 0.44 1.45 0.07 92.52
66 INT208541 Regulation of Positive_regulation of Icmt 1 0.43 0.73 0.03 92.52
67 INT287203 Negative_regulation of Gene_expression of Htt 7 0.37 5.08 0.07 92.44
68 INT331193 Negative_regulation of Gene_expression of Atxn3 1 0.17 0.73 0 92.44
69 INT101552 Binding of CACNA1F 2 0.17 1.95 0.26 92.04
70 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03 91.64
71 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2 91.12
72 INT135045 Gene_expression of Atxn3 34 0.78 11.59 0.36 91.04
73 INT90742 Negative_regulation of Ea2 2 0.05 0.69 0.77 90.80
74 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 90.12
75 INT208542 Negative_regulation of Transcription of Icmt 1 0.41 0.72 0 90.08
76 INT90740 Negative_regulation of Cacna1a 3 0.23 1.43 1.38 89.60
77 INT117024 Negative_regulation of Localization of Acot1 6 0.41 1.56 1.7 89.08
78 INT208535 Regulation of Transcription of Icmt 1 0.43 0.65 0 88.72
79 INT49209 Positive_regulation of GAD1 17 0.70 15.39 5.59 88.52
80 INT19430 Positive_regulation of IGHA1 10 0.67 6.42 2.58 88.52
81 INT45437 Localization of Acot1 84 0.79 17.37 22.18 88.08
82 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 88.04
83 INT208553 Phosphorylation of YWHAQ 4 0.80 3.42 0.36 88.04
84 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 86.92
85 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 86.88
86 INT208537 Regulation of Gene_expression of Gsk3b 4 0.36 2.15 0.52 86.80
87 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 86.68
88 INT85623 Gene_expression of ATXN1 6 0.58 5.14 0.9 86.56
89 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35 86.44
90 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 86.28
91 INT102842 Binding of YWHAQ 6 0.47 3.48 0.86 86.16
92 INT235156 Phosphorylation of Atxn1 1 0.66 0.85 0 86.16
93 INT137449 Positive_regulation of HEPN1 2 0.01 1.46 0.16 86.00
94 INT208548 Positive_regulation of Gene_expression of Icmt 1 0.44 1.76 0.05 85.68
95 INT153090 Transcription of Ea2 1 0.27 1.25 0.08 85.28
96 INT255123 Localization of Mbnl1 7 0.80 3.76 0.24 84.68
97 INT245024 Gene_expression of Top1 1 0.31 0.73 0.07 84.56
98 INT306521 Transcription of Htt 1 0.69 4.13 0.05 84.04
99 INT298884 Binding of RAB7A 1 0.45 9.82 0.14 83.84
100 INT298906 Negative_regulation of Binding of RAB7A 1 0.40 0.99 0 83.84
101 INT69867 Gene_expression of Mip 36 0.75 24.54 10.38 83.72
102 INT210590 Positive_regulation of Gene_expression of Mip 10 0.67 8.09 1.68 83.72
103 INT105569 Binding of IGFALS 13 0.25 17.31 1.36 83.28
104 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26 83.16
105 INT309246 Localization of ATXN2 1 0.10 1.45 0.03 83.16
106 INT309254 Localization of ATXN1 1 0.09 1.45 0.03 83.16
107 INT309258 Localization of TBP 2 0.27 1.78 0.03 83.16
108 INT164193 Localization of ATN1 2 0.73 1.47 0.03 83.16
109 INT309250 Localization of ATXN3 1 0.14 1.46 0.03 83.16
110 INT309256 Localization of ATXN7 1 0.11 1.46 0.03 83.16
111 INT492 Binding of Atxn2 3 0.48 1.26 0.51 82.48
112 INT255112 Negative_regulation of Mbnl1 22 0.58 8.5 0.45 82.40
113 INT255132 Positive_regulation of Mbnl1 15 0.54 2.58 0.27 82.08
114 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65 82.08
115 INT50855 Gene_expression of TRIM21 4 0.65 3.07 0.71 82.04
116 INT277286 Positive_regulation of Positive_regulation of Atxn8os 1 0.49 0.23 0.13 81.84
117 INT148491 Negative_regulation of Map3k3 3 0.02 1.71 1.18 81.76
118 INT199276 Binding of Tbp 12 0.46 2.67 0.24 80.92
119 INT94351 Phosphorylation of PNKP 2 0.82 0.31 0 80.80
120 INT245027 Phosphorylation of Xrcc1 1 0.81 0.31 0 80.32
121 INT277288 Positive_regulation of Atxn8os 1 0.49 0.31 0.13 80.20
122 INT309248 Negative_regulation of ATXN8OS 1 0.06 1.49 0 79.96
123 INT298893 Positive_regulation of Gene_expression of RAB7A 1 0.65 2.86 0 78.60
124 INT255113 Positive_regulation of Gene_expression of Mbnl1 15 0.69 3.28 0.47 78.08
125 INT33327 Positive_regulation of Gene_expression of Gabrg1 39 0.69 9.68 18.82 78.08
126 INT229791 Gene_expression of RAB7A 2 0.73 6.48 1.21 77.96
127 INT17246 Negative_regulation of POLG 16 0.56 9.69 0.79 77.92
128 INT255131 Gene_expression of Mbnl1 34 0.77 10.44 0.55 77.68
129 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 77.68
130 INT277265 Gene_expression of Slc6a11 1 0.75 2.11 1.54 77.68
131 INT245023 Negative_regulation of Xrcc1 1 0.58 0.9 0 77.68
132 INT235132 Gene_expression of Ppp2r2b 1 0.55 2.31 0.11 77.48
133 INT55315 Gene_expression of Tbp 32 0.74 14.6 1.17 77.48
134 INT235160 Gene_expression of Atxn7 1 0.56 2 0.04 77.48
135 INT309244 Transcription of HSPA5 1 0.16 2.75 0.36 77.28
136 INT181802 Localization of Atxn1 6 0.65 3.15 0 77.16
137 INT235136 Positive_regulation of Localization of Atxn1 1 0.38 0.78 0 77.16
138 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 76.72
139 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 76.44
140 INT186508 Regulation of KCNN3 2 0.45 7.41 1.03 76.08
141 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 75.04
142 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03 75.04
143 INT277270 Regulation of Regulation of Mbnl1 1 0.45 0.42 0.14 75.00
144 INT277268 Positive_regulation of Slc6a11 1 0.67 2.47 1.27 75.00
145 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 75.00
146 INT115615 Regulation of SCA25 1 0.36 0.56 0.07 75.00
147 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 74.64
148 INT275456 Binding of Pabpc1 1 0.24 1.62 0 74.20
149 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6 74.16
150 INT254883 Negative_regulation of Positive_regulation of Htt 1 0.05 1.14 0 74.16
151 INT102649 Binding of FRA7G 1 0.23 1.38 0.25 73.40
152 INT237038 Gene_expression of Becn1 18 0.36 13.68 0.31 72.96
153 INT282981 Positive_regulation of Gene_expression of Becn1 8 0.13 6.2 0.06 72.96
154 INT142767 Regulation of Gene_expression of Calb2 1 0.18 0.55 0.11 72.56
155 INT142766 Regulation of Calb2 1 0.18 0.55 0.11 72.56
156 INT142768 Regulation of Cacna1g 2 0.26 1.31 0.11 72.56
157 INT108968 Regulation of Mpz 6 0.54 2.9 0.7 72.40
158 INT57232 Binding of Casp3 22 0.36 9.42 6.2 72.32
159 INT98686 Gene_expression of Calb2 28 0.51 12.07 2.84 72.24
160 INT4415 Gene_expression of Cacna1g 6 0.65 4.64 0.22 72.24
161 INT39060 Gene_expression of Mpz 45 0.77 21.55 4.3 72.00
162 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91 71.96
163 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96 71.76
164 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 70.84
165 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 69.84
166 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 69.40
167 INT205596 Negative_regulation of COQ10A 22 0.51 15.61 2.77 67.12
168 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33 66.72
169 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 66.72
170 INT68694 Positive_regulation of Gene_expression of HTT 7 0.49 4.29 0.29 66.72
171 INT235144 Binding of Anp32a 3 0.44 1.79 0.04 66.00
172 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28 65.84
173 INT235151 Gene_expression of Atxn10 1 0.34 0.73 0 65.72
174 INT186510 Localization of KCNN3 3 0.75 1.6 1.66 65.68
175 INT199649 Gene_expression of Fxn 12 0.72 20.9 0.74 65.52
176 INT235161 Gene_expression of Anp32a 1 0.20 0.73 0 63.56
177 INT236747 Protein_catabolism of Scpep1 2 0.26 1.22 0.03 62.32
178 INT235140 Binding of Atr 1 0.00 1.28 0 61.80
179 INT189925 Binding of Scpep1 5 0.18 1.86 0.16 61.28
180 INT205594 Gene_expression of COQ10A 19 0.67 12.53 2.56 61.20
181 INT235148 Positive_regulation of Binding of Atxn1 1 0.38 0.74 0 61.20
182 INT290982 Positive_regulation of Scpep1 2 0.18 1.07 0.03 60.80
183 INT290983 Gene_expression of 2310033P09Rik 1 0.03 1.71 0.03 60.00
184 INT309255 Gene_expression of NDUFV1 1 0.01 2.33 0 58.60
185 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53 58.20
186 INT251827 Regulation of POLG 3 0.59 2.94 0.04 57.52
187 INT36040 Localization of Itpr3 21 0.70 4.87 7.77 54.96
188 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 52.84
189 INT164248 Positive_regulation of MPZ 18 0.67 24.54 2.16 52.16
190 INT277267 Regulation of Gene_expression of Atxn8os 1 0.44 0.86 0.08 52.04
191 INT17561 Localization of Car2 303 0.79 60.95 44.52 51.92
192 INT235147 Negative_regulation of Localization of Atxn2 1 0.31 0.46 0 51.52
193 INT277273 Regulation of Gene_expression of Klhl1 1 0.47 0.79 0.08 51.44
194 INT235152 Localization of Dnaja1 1 0.17 0.72 0 51.04
195 INT277263 Gene_expression of Klhl1 1 0.59 0.79 0.08 50.96
196 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83 50.64
197 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 50.00
198 INT62919 Regulation of Gnas 22 0.43 5.61 9.55 50.00
199 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28 50.00
200 INT90545 Phosphorylation of Siglec1 53 0.11 12.09 6.81 50.00
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