D:Splenic Rupture

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Disease Term
Synonyms Rupture Splenic, RUPTURES SPLENIC, SPLENIC RUPTURES
Documents 166
Hot Single Events 13
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Splenic Rupture. They are ordered first by their relevance to Splenic Rupture and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT92390 ALK Positive_regulation of Gene_expression of Tnfrsf8 1 0.45 1.14 0.09 93.64
2 INT92389 ALK Positive_regulation of Gene_expression of Map3k1 1 0.01 1.14 0.09 92.48
3 INT277765 Binding of BCR and Abl1 1 0.18 1.55 0.03 5.00
4 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Splenic Rupture. They are ordered first by their pain relevance and then by number of times they were reported in Splenic Rupture. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.96
2 INT14690 Localization of CSF2 124 0.80 85.17 27.26 99.72
3 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65 99.52
4 INT92386 Gene_expression of Tnfrsf8 14 0.54 13.55 1.67 93.64
5 INT14301 Binding of CSF2 82 0.48 67.95 8.98 92.80
6 INT92387 Gene_expression of Map3k1 1 0.02 1.13 0.09 92.48
7 INT92388 Gene_expression of ALK 16 0.78 22.46 2.26 92.08
8 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03 89.08
9 INT132938 Phosphorylation of Insrr 21 0.03 10.55 8.88 87.96
10 INT110445 Phosphorylation of Gtf3a 15 0.09 5.58 3.07 87.96
11 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43 87.96
12 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 87.68
13 INT147464 Binding of Ptprc 13 0.36 15.18 0.98 84.36
14 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 79.56
15 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59 78.16
16 INT74233 Binding of Ssr1 8 0.41 1.67 0.35 75.00
17 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 74.72
18 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 73.28
19 INT25962 Gene_expression of COX8A 25 0.75 20.04 2.62 70.08
20 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16 69.08
21 INT91152 Regulation of Pecam1 4 0.30 4.14 0.42 63.36
22 INT91151 Regulation of Flt4 1 0.06 1.96 0.15 63.36
23 INT284 Positive_regulation of Ggt6 18 0.67 13.56 4.62 60.76
24 INT96188 Binding of Cd34 11 0.31 10.4 0.82 57.76
25 INT32795 Positive_regulation of Hypism 17 0.15 20.16 1.73 56.64
26 INT105021 Binding of GOPC 187 0.40 60.39 20.38 50.00
27 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 50.00
28 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 50.00
29 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 50.00
30 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 50.00
31 INT117934 Gene_expression of Cd38 11 0.68 6.5 1.95 50.00
32 INT194253 Positive_regulation of FIG4 2 0.27 1.39 0.12 50.00
33 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 28.64
34 INT14689 Localization of CSF3R 5 0.56 3.85 1.02 25.00
35 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37 23.76
36 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44 14.56
37 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
38 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
39 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
40 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
41 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
42 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
43 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
44 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
45 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
46 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 5.00
47 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 5.00
48 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39 5.00
49 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 5.00
50 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 5.00
51 INT264641 Binding of AES 25 0.42 18.56 6.98 5.00
52 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 5.00
53 INT201130 Localization of AES 31 0.63 25.45 5.12 5.00
54 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76 5.00
55 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
56 INT17182 Binding of Cea 25 0.48 14.98 4.16 5.00
57 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 5.00
58 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 5.00
59 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
60 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57 5.00
61 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92 5.00
62 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87 5.00
63 INT67604 Gene_expression of SERPINC1 14 0.67 11.47 1.72 5.00
64 INT207035 Gene_expression of CFB 4 0.63 18.4 1.72 5.00
65 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43 5.00
66 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 5.00
67 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14 5.00
68 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04 5.00
69 INT139019 Negative_regulation of STAT1 10 0.57 5.04 0.97 5.00
70 INT122813 Binding of Krt20 11 0.32 13.77 0.88 5.00
71 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 5.00
72 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75 5.00
73 INT98456 Negative_regulation of Src 17 0.42 8.3 0.42 5.00
74 INT277761 Gene_expression of DPM1 1 0.03 9.23 0.27 5.00
75 INT277757 Gene_expression of Pmf1 3 0.12 4.14 0.23 5.00
76 INT241498 Regulation of Abl1 8 0.32 6.46 0.22 5.00
77 INT192748 Localization of BCR 4 0.68 2.4 0.18 5.00
78 INT200802 Regulation of Jak2 5 0.61 2.86 0.16 5.00
79 INT277760 Positive_regulation of DPM1 1 0.02 1.68 0.11 5.00
80 INT277758 Negative_regulation of Fip1l1 1 0.06 0.5 0.04 5.00
81 INT241506 Localization of Abl1 2 0.54 2.37 0.04 5.00
82 INT207034 Binding of CFB 3 0.17 0.61 0.03 5.00
83 INT299486 Localization of Krt20 2 0.19 1.49 0 5.00
84 INT277762 Negative_regulation of Negative_regulation of STAT1 1 0.42 0.29 0 5.00
85 INT174983 Regulation of HTN3 1 0.00 0.63 0 5.00
86 INT136181 Negative_regulation of BCR 5 0.42 2.94 0 5.00
87 INT201927 Regulation of BCR 2 0.26 1.94 0 5.00
88 INT277764 Regulation of DPM1 1 0.01 1.37 0 5.00
89 INT277763 Localization of DPM1 1 0.03 2.34 0 5.00
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