D:Splenomegaly

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Disease Term
Synonyms ENLARGED SPLEEN, Spleen Enlarged
Documents 915
Hot Single Events 200
Hot Interactions 11

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Splenomegaly. They are ordered first by their relevance to Splenomegaly and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0 98.60
2 INT228136 Trav6-3 Positive_regulation of Positive_regulation of Fasl 1 0.14 0.59 0.04 94.84
3 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28 92.92
4 INT228110 Chrm2 Positive_regulation of Localization of Il10 1 0.33 0.66 0.13 89.84
5 INT350503 Binding of HSP90AA1 and JAK2 1 0.06 1.39 0 89.00
6 INT350505 Negative_regulation of Binding of HSP90AA1 and JAK2 1 0.07 1.5 0 89.00
7 INT184108 Csf3 Positive_regulation of Mapk1 1 0.09 0.64 0.08 86.52
8 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 83.88
9 INT209615 Binding of KRT20 and Cd34 1 0.00 1.05 0.06 83.12
10 INT209610 Binding of Cd22 and Cd34 1 0.01 1.05 0.06 82.88
11 INT209611 Binding of Mme and Cd34 1 0.00 1.05 0.06 82.64
12 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06 77.60
13 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03 72.56
14 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 68.36
15 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 68.36
16 INT301243 Mir29a Positive_regulation of Mvd 1 0.03 1.66 0 66.64
17 INT184119 Socs3 Negative_regulation of Csf3 1 0.21 0.64 0.08 64.56
18 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 63.80
19 INT184124 Socs3 Regulation of Il6 1 0.13 1.4 0.43 63.12
20 INT184128 Socs3 Negative_regulation of Il6 1 0.12 1.14 0.36 63.12
21 INT283632 Binding of Selp and Ie 1 0.00 0.22 0 59.36
22 INT214886 Binding of Atcay and FIP1L1 1 0.08 4.06 0 58.56
23 INT214885 Binding of PDGFRA and Atcay 1 0.08 4.05 0 58.56
24 INT283633 Binding of Vcam1 and Ie 1 0.00 0.17 0 58.24
25 INT283630 Cd36 Regulation of Positive_regulation of Ie 1 0.00 0 0 41.76
26 INT283631 Positive_regulation of Binding of Cd36 and Ie 1 0.00 0 0 41.76
27 INT283629 Binding of Cd36 and Ie 1 0.00 0 0 41.76
28 INT226786 Scl1 Positive_regulation of Lbp 1 0.04 1.68 0.07 35.24
29 INT226787 Trglyd Positive_regulation of Lbp 1 0.04 1.67 0.07 34.48
30 INT228120 PDLIM7 Positive_regulation of Localization of Il10 1 0.51 1.37 0 29.24
31 INT312794 Hdl1 Regulation of Pon1 1 0.02 1.63 0.15 29.12
32 INT312304 Binding of JAK2 and VEGFA 1 0.30 0.82 0 27.76
33 INT184098 Binding of Il4 and Socs5 1 0.09 2.05 0.15 27.72
34 INT314965 Binding of Lbr and Blvrb 1 0.00 0.13 0 25.24
35 INT293950 Binding of CTNND2 and Spn 1 0.06 1.69 0 24.40
36 INT184137 Binding of Socs5 and Regulation of Hand2 1 0.09 1.01 0 24.08
37 INT184093 Negative_regulation of Il4 Positive_regulation of Stat6 1 0.08 0.93 0 21.40
38 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 20.88
39 INT301242 Mvd Positive_regulation of Gene_expression of Mir29a 1 0.04 0.1 0 15.28
40 INT202508 Gpbar1 Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.57 0.19 14.48
41 INT277765 Binding of BCR and Abl1 1 0.18 1.55 0.03 13.36
42 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
43 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
44 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11 5.00
45 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
46 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
47 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9 5.00
48 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83 5.00
49 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77 5.00
50 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
51 INT11684 Binding of CSF2 and IL3 6 0.36 3.3 0.72 5.00
52 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7 5.00
53 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61 5.00
54 INT270099 Negative_regulation of Binding of CPOX and PLA2G2A 1 0.01 0.51 0.59 5.00
55 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 0.01 0.51 0.59 5.00
56 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58 5.00
57 INT270103 Binding of CPOX and PLA2G2A 1 0.01 0.5 0.58 5.00
58 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57 5.00
59 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57 5.00
60 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 0.01 0.49 0.57 5.00
61 INT333477 CXCL10 Positive_regulation of TH1L 1 0.14 0.32 0.56 5.00
62 INT270101 CPOX Negative_regulation of PLA2G2A 1 0.01 0.48 0.56 5.00
63 INT184111 Epo Positive_regulation of Il7 1 0.06 0.26 0.52 5.00
64 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52 5.00
65 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52 5.00
66 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51 5.00
67 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51 5.00
68 INT184099 Il4 Positive_regulation of Stat4 1 0.13 0.28 0.49 5.00
69 INT184105 Il6 Positive_regulation of Socs3 2 0.42 1.34 0.48 5.00
70 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48 5.00
71 INT184117 Il12a Positive_regulation of Stat6 1 0.07 0.28 0.48 5.00
72 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43 5.00
73 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
74 INT352985 IL4 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
75 INT184138 Ik Positive_regulation of Stat3 1 0.01 0.29 0.43 5.00
76 INT184135 Il11ra1 Positive_regulation of Stat3 1 0.20 0.3 0.4 5.00
77 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4 5.00
78 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39 5.00
79 INT184092 Il11ra1 Positive_regulation of Jak1 1 0.17 0.3 0.39 5.00
80 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38 5.00
81 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38 5.00
82 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36 5.00
83 INT184142 Il6 Negative_regulation of Positive_regulation of TNF 1 0.02 0.48 0.35 5.00
84 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34 5.00
85 INT184095 Il10 Positive_regulation of Socs3 1 0.21 0.49 0.34 5.00
86 INT184082 Binding of Socs3 and Il6 1 0.11 0.49 0.33 5.00
87 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33 5.00
88 INT184110 Jak1 Positive_regulation of Stat1 1 0.32 0.3 0.33 5.00
89 INT184107 Cish Negative_regulation of Ik 1 0.01 0.1 0.32 5.00
90 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 5.00
91 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 5.00
92 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 5.00
93 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28 5.00
94 INT184141 Il6 Positive_regulation of Gene_expression of IFNA1 1 0.01 0.43 0.28 5.00
95 INT279266 CADPS Positive_regulation of Regulation of IL1B 1 0.22 1.43 0.28 5.00
96 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
97 INT312768 Pon1 Negative_regulation of Gene_expression of Ccl2 1 0.06 1.42 0.26 5.00
98 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 5.00
99 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25 5.00
100 INT292621 Binding of IL6 and Gpt 1 0.01 3.88 0.24 5.00
101 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24 5.00
102 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 5.00
103 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
104 INT345924 IL6 Regulation of Gene_expression of SPHAR 1 0.00 0.21 0.18 5.00
105 INT329841 Il4 Regulation of Hand1 1 0.04 0.87 0.18 5.00
106 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18 5.00
107 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18 5.00
108 INT329670 Csf2 Regulation of Col7a1 1 0.03 0.4 0.17 5.00
109 INT184103 Binding of Socs3 and Il11ra1 1 0.12 0 0.17 5.00
110 INT184086 Socs5 Negative_regulation of Binding of Jak1 1 0.20 0 0.16 5.00
111 INT292615 Binding of IL6 and SLC17A5 1 0.01 1.8 0.16 5.00
112 INT258906 Binding of HLA-B and HLA-DRB1 1 0.31 1.36 0.15 5.00
113 INT258909 Binding of HLA-DOA and NDUFA2 1 0.03 1.44 0.15 5.00
114 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14 5.00
115 INT312793 Binding of Hdl1 and Pon3 1 0.00 0.84 0.14 5.00
116 INT184109 Binding of Gopc and Sh2 1 0.03 0 0.14 5.00
117 INT184104 Binding of Socs3 and Gopc 1 0.10 0 0.14 5.00
118 INT184122 Binding of Socs1 and Sh2 1 0.14 0 0.14 5.00
119 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 5.00
120 INT228111 Il10 Negative_regulation of Gene_expression of Ik 1 0.01 0.44 0.13 5.00
121 INT228119 Il10 Negative_regulation of H2 1 0.07 0.38 0.13 5.00
122 INT354888 Amy1 Regulation of Il10 1 0.02 1.41 0.13 5.00
123 INT184129 Socs2 Negative_regulation of Stat5a 1 0.22 0.05 0.13 5.00
124 INT354885 Amy1 Regulation of Gene_expression of Il10 1 0.03 1.41 0.13 5.00
125 INT184091 Socs2 Negative_regulation of Gh 1 0.11 0.05 0.13 5.00
126 INT228113 H2 Negative_regulation of Gene_expression of Ik 1 0.00 0.33 0.13 5.00
127 INT193697 Apaf1 Positive_regulation of CASP9 1 0.02 1.84 0.12 5.00
128 INT220905 Cfb Positive_regulation of C3 1 0.06 0.91 0.11 5.00
129 INT265919 Binding of PLEK and Adp 1 0.01 0.38 0.11 5.00
130 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
131 INT209952 Binding of SNRNP70 and IGKV2-19 1 0.00 0.47 0.11 5.00
132 INT312792 Binding of Pon1 and Hdl1 1 0.04 1.85 0.11 5.00
133 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1 5.00
134 INT184139 Gh Positive_regulation of Gh Positive_regulation of Stat5b 1 0.06 1.31 0.1 5.00
135 INT184089 Gh Positive_regulation of Stat5b 1 0.13 1.3 0.1 5.00
136 INT184140 Socs2 Negative_regulation of Gh Positive_regulation of Stat5b 1 0.10 1.33 0.1 5.00
137 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09 5.00
138 INT200811 Epo Positive_regulation of Akt1 2 0.30 1.77 0.09 5.00
139 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09 5.00
140 INT274233 Negative_regulation of Binding of Cd4 and Fasl 1 0.13 0.91 0.08 5.00
141 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 5.00
142 INT228137 Binding of Serpinb1-ps1 and Trav6-3 2 0.02 1.93 0.08 5.00
143 INT297589 Binding of HAT1 and Il10 1 0.00 1.14 0.08 5.00
144 INT202505 Binding of Cd40lg and Positive_regulation of Positive_regulation of Nfasc 1 0.09 0.45 0.08 5.00
145 INT274232 Binding of Cd4 and Fasl 1 0.11 0.9 0.08 5.00
146 INT228116 Tlr4 Positive_regulation of Localization of Il10 1 0.09 0.06 0.08 5.00
147 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08 5.00
148 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08 5.00
149 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08 5.00
150 INT184113 Socs1 Negative_regulation of Mthfd1 1 0.08 0.5 0.08 5.00
151 INT184126 Gh Positive_regulation of Gene_expression of Socs2 1 0.14 1.25 0.08 5.00
152 INT297559 Binding of IL6 and HAT1 1 0.00 1.13 0.08 5.00
153 INT279286 Binding of TXK and VEGFA 3 0.05 2.35 0.07 5.00
154 INT184097 Cish Negative_regulation of Il3 1 0.10 0.62 0.07 5.00
155 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
156 INT184102 Cish Negative_regulation of Thpo 1 0.14 0.62 0.07 5.00
157 INT184121 Socs1 Regulation of Mthfd1 1 0.05 0.44 0.07 5.00
158 INT274231 Fasl Positive_regulation of Gene_expression of Cd8a 1 0.03 1.01 0.07 5.00
159 INT297562 TNF Positive_regulation of IFNA1 1 0.00 0.62 0.06 5.00
160 INT295130 Igf1 Regulation of Grxcr1 1 0.02 0.64 0.06 5.00
161 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06 5.00
162 INT295128 Igf1 Regulation of Transcription of Pou1f1 1 0.16 0.64 0.06 5.00
163 INT345925 IL6 Negative_regulation of Gene_expression of CYP1A2 1 0.13 0.18 0.06 5.00
164 INT202506 Psmb8 Positive_regulation of Nfasc 1 0.01 0.59 0.06 5.00
165 INT295120 Bmp2 Regulation of Transcription of Pou1f1 1 0.24 0.66 0.06 5.00
166 INT325769 Binding of EPOR and Positive_regulation of Phosphorylation of JAK2 1 0.66 0 0.06 5.00
167 INT329839 Negative_regulation of Tnfsf13b Negative_regulation of Gene_expression of Ighm 1 0.05 2.28 0.06 5.00
168 INT220903 Regulation of Binding of Crp and Cd40 1 0.05 0.37 0.05 5.00
169 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
170 INT220906 Binding of Crp and Cd40 1 0.04 0.37 0.05 5.00
171 INT184123 Socs3 Positive_regulation of Protein_catabolism of Insr 1 0.03 0.41 0.05 5.00
172 INT184133 Binding of Gh and Socs2 1 0.10 0.66 0.05 5.00
173 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05 5.00
174 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05 5.00
175 INT184085 Socs1 Positive_regulation of Protein_catabolism of Insr 1 0.04 0.41 0.05 5.00
176 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00
177 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 5.00
178 INT184083 Positive_regulation of Gh Positive_regulation of Igf1 1 0.09 0.7 0.04 5.00
179 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04 5.00
180 INT205862 CNTN2 Positive_regulation of TNF 1 0.01 0.08 0.04 5.00
181 INT184115 Igf1 Positive_regulation of Gene_expression of Socs2 1 0.16 0.62 0.04 5.00
182 INT315803 Binding of FL and Tst 1 0.04 0.66 0.04 5.00
183 INT314967 Binding of Cd4 and Mthfd1 1 0.09 0.11 0.04 5.00
184 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04 5.00
185 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03 5.00
186 INT184101 Binding of Irs2 and Sh2 1 0.05 0.15 0.03 5.00
187 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03 5.00
188 INT280569 Binding of GEM and HIVEP1 1 0.00 1.59 0.03 5.00
189 INT200809 Binding of Akt1 and Epo 1 0.23 0.98 0.03 5.00
190 INT184136 Binding of Socs7 and Irs2 1 0.13 0.15 0.03 5.00
191 INT184118 Binding of Irs4 and Socs7 1 0.13 0.15 0.03 5.00
192 INT184131 Binding of Socs6 and Irs2 1 0.11 0.2 0.03 5.00
193 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03 5.00
194 INT280601 Binding of HIVEP1 and Dbi 1 0.00 1.57 0.03 5.00
195 INT184127 Binding of Irs4 and Sh2 1 0.05 0.15 0.03 5.00
196 INT184134 Binding of Cish and Rbx1 1 0.10 0 0.03 5.00
197 INT200823 Akt1 Negative_regulation of Binding of Akt1 and Insrr 1 0.00 0.98 0.03 5.00
198 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03 5.00
199 INT184087 Binding of Cish and Cul2 1 0.10 0 0.03 5.00
200 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Splenomegaly. They are ordered first by their pain relevance and then by number of times they were reported in Splenomegaly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT37949 Positive_regulation of CTSC 3 0.42 1.05 0.09 100.00
2 INT186281 Positive_regulation of Binding of Il12a 2 0.26 2.09 0 100.00
3 INT209783 Binding of SLC15A4 2 0.04 1.25 0.3 99.92
4 INT174160 Binding of Il12a 19 0.24 12.61 3.4 99.92
5 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98 99.90
6 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 99.82
7 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 99.80
8 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 99.76
9 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74 99.76
10 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64 99.60
11 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76 99.56
12 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 99.52
13 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 99.40
14 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67 99.38
15 INT234263 Negative_regulation of ELF3 6 0.39 3.9 0.04 99.38
16 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37 99.20
17 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 98.88
18 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 98.78
19 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36 98.64
20 INT87239 Localization of Il12a 51 0.75 31.95 12.05 98.60
21 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36 98.56
22 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 98.48
23 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 98.40
24 INT62868 Gene_expression of Ifna 15 0.67 5.37 0.51 98.40
25 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77 98.40
26 INT14238 Positive_regulation of Cd69 19 0.60 17.75 6.07 98.28
27 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 98.28
28 INT169222 Negative_regulation of Positive_regulation of Cd69 2 0.42 0.97 0.76 98.28
29 INT166764 Localization of Mtor 2 0.75 1.28 1.42 98.20
30 INT38299 Negative_regulation of FCGR2C 6 0.21 3.92 0.52 98.16
31 INT44608 Gene_expression of C2 45 0.75 15.84 5.05 98.16
32 INT44614 Gene_expression of FCGR2C 7 0.29 5.6 0.68 98.16
33 INT28308 Localization of SLC17A5 10 0.73 6.77 0.7 98.12
34 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 98.08
35 INT57105 Positive_regulation of CD33 7 0.45 5.08 0.63 97.88
36 INT18480 Positive_regulation of ANPEP 9 0.59 5.18 2.13 97.88
37 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 97.76
38 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59 97.76
39 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 97.52
40 INT81578 Gene_expression of TRAP 25 0.72 9.75 2.82 97.52
41 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93 97.52
42 INT241797 Gene_expression of CHIT1 10 0.24 9.75 0.69 97.52
43 INT241798 Negative_regulation of Gene_expression of CHIT1 4 0.15 2.07 0.1 97.52
44 INT333986 Negative_regulation of Gene_expression of TRAP 3 0.32 0.77 0 97.52
45 INT147464 Binding of Ptprc 13 0.36 15.18 0.98 97.48
46 INT100861 Binding of CRP 179 0.48 175.2 26.45 97.44
47 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02 97.44
48 INT206528 Negative_regulation of Gene_expression of Ptprc 8 0.34 3.91 1.61 97.44
49 INT62031 Gene_expression of Cd19 27 0.65 10.39 0.93 97.44
50 INT201346 Negative_regulation of Gene_expression of Cd19 3 0.32 2.1 0.05 97.44
51 INT44540 Binding of GPT 3 0.36 6.14 0.23 97.38
52 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 97.36
53 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 97.36
54 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 96.88
55 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 96.84
56 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 96.84
57 INT207134 Positive_regulation of tryptase 11 0.47 11.16 1.21 96.70
58 INT9655 Regulation of Il6 98 0.62 70.92 31.95 96.52
59 INT310677 Localization of ARSB 1 0.71 5.72 0.14 96.44
60 INT62360 Positive_regulation of PTHLH 31 0.70 28.23 3.46 96.16
61 INT35612 Gene_expression of REG3A 37 0.78 33.33 10.13 96.16
62 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 96.00
63 INT209602 Positive_regulation of Gene_expression of Cd22 4 0.19 3.25 0.33 96.00
64 INT37390 Regulation of Crp 39 0.46 28.74 11.45 95.84
65 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 95.56
66 INT66852 Gene_expression of Fcer2 15 0.14 9.74 1.27 95.56
67 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 95.56
68 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 95.56
69 INT117661 Gene_expression of Cd22 7 0.30 5.69 0.62 95.56
70 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 95.48
71 INT317823 Positive_regulation of Negative_regulation of Mvk 2 0.30 3.33 0.62 95.00
72 INT284362 Positive_regulation of Mvk 3 0.44 3.32 0.46 95.00
73 INT14971 Regulation of Afp 12 0.44 11.35 1.48 94.96
74 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 94.88
75 INT140071 Negative_regulation of Positive_regulation of Cd4 5 0.39 3.9 0.42 94.88
76 INT39512 Negative_regulation of TRAP 22 0.56 8.18 4.76 94.72
77 INT39513 Positive_regulation of TRAP 14 0.48 5.11 1.67 94.72
78 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 94.64
79 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 94.60
80 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 94.56
81 INT284359 Negative_regulation of Mvk 4 0.37 6.62 0.99 94.48
82 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98 94.40
83 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 94.24
84 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 94.24
85 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 93.92
86 INT125227 Positive_regulation of CHIT1 5 0.21 3.52 0.33 93.84
87 INT241799 Negative_regulation of CHIT1 13 0.42 4.37 0.44 93.84
88 INT66261 Negative_regulation of Ccl21a 5 0.42 1.04 2.1 93.68
89 INT37168 Positive_regulation of APCS 22 0.67 9.61 4.59 93.60
90 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 93.52
91 INT35910 Binding of Mme 8 0.37 4.79 3.16 93.52
92 INT96188 Binding of Cd34 11 0.31 10.4 0.82 93.52
93 INT169568 Binding of Fcer2 3 0.06 2.12 0.33 93.52
94 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 93.52
95 INT38814 Positive_regulation of Aspt1 9 0.63 6.89 3.06 93.52
96 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89 93.44
97 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 93.32
98 INT76751 Negative_regulation of Protein_catabolism of F13A1 7 0.13 5.16 0.79 93.32
99 INT39072 Negative_regulation of Positive_regulation of Serpinc1 2 0.36 1.24 0.43 93.32
100 INT49284 Regulation of MYOM2 2 0.08 3.27 0.13 93.32
101 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 93.12
102 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 93.04
103 INT6481 Binding of TNF 624 0.48 510.2 214.82 93.00
104 INT14960 Positive_regulation of Serpinc1 17 0.68 12.71 3.02 92.92
105 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 92.76
106 INT83325 Regulation of Gene_expression of Il2ra 8 0.48 3.59 2.36 92.76
107 INT111143 Regulation of Gene_expression of KRT20 22 0.26 5.65 1.93 92.76
108 INT111138 Regulation of Gene_expression of Fcer2 1 0.05 0.43 0.09 92.76
109 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 92.56
110 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 92.56
111 INT3738 Regulation of Epo 25 0.61 13.73 6.18 92.48
112 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 92.40
113 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 92.40
114 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 92.32
115 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08 92.24
116 INT184061 Negative_regulation of Stat5a 2 0.29 1.85 0.04 92.24
117 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 92.20
118 INT35740 Regulation of GGT2 1 0.02 0.88 0.13 92.20
119 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 92.16
120 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 92.12
121 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 92.08
122 INT84430 Negative_regulation of Smpd1 22 0.59 10.33 3.95 92.08
123 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 92.08
124 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 91.96
125 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41 91.92
126 INT189852 Localization of H2-Q13 4 0.06 4.1 0.47 91.88
127 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65 91.84
128 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 91.84
129 INT57338 Gene_expression of ITGAX 31 0.75 24.62 4.39 91.84
130 INT109596 Gene_expression of Itgae 5 0.42 2.82 0.28 91.84
131 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 91.68
132 INT8772 Positive_regulation of Gene_expression of HBG1 16 0.68 6.93 0.95 91.68
133 INT105131 Gene_expression of KRT122P 8 0.58 9.1 0.7 91.68
134 INT310071 Gene_expression of PMCH 2 0.53 0.51 0.17 91.64
135 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09 91.60
136 INT11984 Gene_expression of IGHA1 9 0.54 6.12 1.35 91.48
137 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 91.36
138 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 91.32
139 INT105114 Gene_expression of Arigg4 16 0.52 21.88 4.56 91.12
140 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 91.08
141 INT20200 Positive_regulation of Serpinc1 25 0.68 17.08 4.98 91.08
142 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28 91.08
143 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 91.00
144 INT173693 Localization of Gopc 249 0.65 70.49 38.81 91.00
145 INT12163 Positive_regulation of OLAH 8 0.68 6.91 1.67 90.88
146 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 90.80
147 INT18969 Gene_expression of HLA-DQA1 29 0.65 12.19 2.54 90.80
148 INT285409 Positive_regulation of Positive_regulation of ELF3 2 0.27 1.21 0 90.80
149 INT191601 Negative_regulation of Fdft1 2 0.04 2.13 0.33 90.68
150 INT2139 Negative_regulation of Cea 55 0.43 43.59 9.14 90.56
151 INT44611 Negative_regulation of APOC1P1 1 0.02 0.84 0.09 90.56
152 INT44609 Negative_regulation of Positive_regulation of APOE 1 0.16 0.9 0.09 90.56
153 INT62070 Transcription of PTHLH 3 0.72 1.57 0.22 90.28
154 INT97798 Localization of IRF6 86 0.73 33.27 20.94 90.16
155 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 90.16
156 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 90.16
157 INT44613 Gene_expression of APOC1P1 1 0.02 0.83 0.09 90.16
158 INT55529 Negative_regulation of Gba 13 0.59 7.91 2.1 90.08
159 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39 89.96
160 INT22389 Regulation of MLN 9 0.61 4.39 3.08 89.76
161 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86 89.72
162 INT158630 Positive_regulation of Positive_regulation of Stat3 16 0.49 14.75 3.08 89.72
163 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 89.64
164 INT9884 Localization of CD79A 41 0.78 21.75 3.06 89.64
165 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 89.60
166 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 89.60
167 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 89.60
168 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93 89.60
169 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36 89.60
170 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 89.60
171 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8 89.44
172 INT52937 Gene_expression of Cd68 37 0.67 31.33 7.54 89.40
173 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 89.40
174 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 89.20
175 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 89.20
176 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 89.20
177 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01 89.20
178 INT71308 Gene_expression of CCL11 33 0.76 25.66 7.83 89.20
179 INT99298 Positive_regulation of ITGA3 6 0.06 2.94 1.54 88.92
180 INT21299 Negative_regulation of Hp 14 0.44 10.97 2.97 88.76
181 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 88.72
182 INT140561 Regulation of Gene_expression of Thpo 3 0.60 2.21 0.87 88.72
183 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 88.64
184 INT28249 Positive_regulation of HLA-DRA 25 0.70 13.63 3.25 88.64
185 INT17701 Gene_expression of PTHLH 103 0.78 64.23 8.85 88.60
186 INT228130 Positive_regulation of Bcl2l11 14 0.49 10 0.9 88.60
187 INT90792 Localization of Il10 144 0.80 87.88 30.03 88.32
188 INT42378 Positive_regulation of Socs3 21 0.67 15.81 5.71 88.28
189 INT105130 Positive_regulation of Arigg3 2 0.02 2.11 0.44 88.28
190 INT95616 Gene_expression of Thpo 48 0.78 21.51 5.88 88.20
191 INT8792 Gene_expression of GBA 20 0.78 14.73 1.98 88.16
192 INT94341 Gene_expression of D9Mit53 1 0.00 1.11 0.12 87.64
193 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89 87.48
194 INT14867 Gene_expression of Igh-6 47 0.67 30.05 11.75 87.32
195 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 87.24
196 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 87.20
197 INT44610 Positive_regulation of APOC1P1 1 0.02 0.82 0.09 87.12
198 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 86.68
199 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 86.44
200 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72 86.44
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