D:Starvation

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pChart

Disease Term
Synonyms FAMINE, Famines, Starvations
Documents 434
Hot Single Events 200
Hot Interactions 41

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Starvation. They are ordered first by their relevance to Starvation and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT297852 Nanos2 Positive_regulation of Positive_regulation of Gopc 1 0.07 0.1 0 100.00
2 INT297856 Pdk4 Positive_regulation of Positive_regulation of Gopc 1 0.07 0.1 0 100.00
3 INT297853 Nanos2 Positive_regulation of Positive_regulation of Snord116 1 0.49 0.1 0 100.00
4 INT297849 Pdk4 Positive_regulation of Positive_regulation of Snord116 1 0.50 0.1 0 100.00
5 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0 99.84
6 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14 99.66
7 INT331231 Binding of Bcl2 and Mapk8 1 0.01 0.77 0 99.32
8 INT331230 Binding of Mapk8 and Becn1 1 0.02 0.77 0 99.32
9 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44 99.20
10 INT283001 Binding of Becn1 and Om 1 0.00 0.1 0 99.00
11 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24 98.72
12 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23 98.72
13 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22 98.72
14 INT297846 Nanos2 Regulation of Dnmt3l 1 0.34 0.6 0 97.76
15 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15 97.76
16 INT297851 Nanos2 Regulation of Stra8 1 0.35 0.6 0 97.44
17 INT157266 PPARA Positive_regulation of ADIPOR1 1 0.00 1.19 0.09 95.52
18 INT157274 Adipoq Positive_regulation of ADIPOR1 1 0.00 1.2 0.09 95.52
19 INT356276 Egf Positive_regulation of Positive_regulation of Mapk1 1 0.05 0.52 0.12 95.12
20 INT356270 Ngf Positive_regulation of Positive_regulation of Mapk1 1 0.05 0.25 0 95.12
21 INT356271 Gdnf Positive_regulation of Positive_regulation of Mapk1 1 0.05 0.25 0 95.12
22 INT297850 Snx1 Positive_regulation of Protein_catabolism of P9Ehs1 1 0.01 0.31 0.05 94.80
23 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2 94.72
24 INT157265 PPARG Positive_regulation of PPARA 1 0.22 1.15 0.09 94.72
25 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09 94.16
26 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28 93.72
27 INT327333 Binding of TNF and Fxr1 1 0.06 3.74 0.48 93.68
28 INT220052 Binding of Col7a1 and Cia1 1 0.01 1.11 0.38 92.80
29 INT218616 Binding of IGFBP3 and INS 1 0.07 0.68 0.05 92.16
30 INT220462 VEGFA Regulation of FN1 1 0.05 1.28 0 91.20
31 INT220460 VEGFA Regulation of BAG6 1 0.02 1.28 0 91.20
32 INT309662 C5 Positive_regulation of Akt1 1 0.30 0.43 0.11 90.84
33 INT329216 Prkag1 Regulation of Mtor 1 0.01 0.35 0.04 90.52
34 INT329223 Prkag1 Regulation of Rps6kb1 1 0.14 0.35 0.04 90.52
35 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0 89.92
36 INT218614 INS Positive_regulation of Binding of IGF1 1 0.39 0.79 0.05 85.92
37 INT307214 Hnf4a Regulation of Ppara 1 0.18 0.35 0 85.64
38 INT41024 Nts Negative_regulation of Ins1 1 0.14 0.22 0.22 84.44
39 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38 83.64
40 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38 82.36
41 INT356285 Binding of Stat3 and Egf 1 0.09 0.4 0.13 81.08
42 INT335023 Fgf21 Positive_regulation of Gene_expression of Igf1 1 0.49 0.65 0.05 79.76
43 INT307212 Ide Regulation of Lep 1 0.00 0.51 0 78.80
44 INT316248 ESR1 Regulation of Gene_expression of TRPM8 1 0.34 0.17 0.05 76.48
45 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08 76.16
46 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38 75.60
47 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19 75.60
48 INT297848 Binding of Fzd4 and Ndp 1 0.04 1.19 0 74.08
49 INT331237 Negative_regulation of IMPA1 Negative_regulation of Itpr3 1 0.00 0.52 0 73.08
50 INT246466 GHS Positive_regulation of GHS Regulation of Gh 1 0.01 0.6 0.1 72.40
51 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0 72.16
52 INT246468 GHS Regulation of Gh 1 0.05 1.12 0.19 72.08
53 INT263584 Hspa5 Positive_regulation of Myo1b 1 0.00 1.02 0 71.00
54 INT263586 Hspa5 Positive_regulation of Esr1 1 0.15 1.01 0 71.00
55 INT343158 ACSL4 Regulation of Regulation of ALOX15 1 0.01 0.47 0 68.40
56 INT331221 Binding of Akt1 and Tsc1 1 0.03 0.33 0 67.28
57 INT331224 Binding of Akt1 and Tsc2 1 0.03 0.33 0 67.08
58 INT322207 CCL18 Regulation of Gene_expression of COL7A1 1 0.07 0.88 0.09 66.76
59 INT97896 Ghrl Positive_regulation of Localization of Gh 1 0.48 0.37 0.03 65.92
60 INT192106 Regulation of Binding of Rara and Retsat 1 0.00 0.83 0.13 65.32
61 INT192102 Regulation of Binding of Rxrg and Retsat 1 0.01 0.83 0.13 65.32
62 INT192101 Binding of Rxrg and Regulation of Retsat 1 0.00 0.83 0.13 65.32
63 INT192103 Binding of Rxrg and Retsat 1 0.01 0.83 0.13 64.56
64 INT192105 Binding of Rara and Retsat 1 0.00 0.83 0.13 64.56
65 INT331238 Binding of ULK1 and Pik3r1 1 0.09 0.48 0 63.40
66 INT246467 GHS Regulation of Localization of Gh 1 0.03 0.52 0.09 63.28
67 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22 63.20
68 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7 63.20
69 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85 63.20
70 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1 62.96
71 INT157264 PPARA Positive_regulation of PRKAA1 1 0.03 0.92 0.08 61.60
72 INT157263 PPARA Positive_regulation of APRT 1 0.54 0.92 0.08 61.60
73 INT157270 PPARA Positive_regulation of Adipor2 1 0.05 0.92 0.08 61.60
74 INT236723 VEGFA Positive_regulation of Positive_regulation of Ppara 1 0.12 1.01 0 59.08
75 INT331234 Binding of Becn1 and Pik3c3 Positive_regulation of Pik3c3 1 0.00 0.47 0 58.76
76 INT331226 Binding of Becn1 and Pik3c3 1 0.02 0.47 0 58.76
77 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41 58.52
78 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0 56.76
79 INT331236 Binding of RASA1 and Mtor 1 0.00 0.32 0 56.76
80 INT157268 Adipor1 Positive_regulation of Adipor2 1 0.01 0.89 0.08 56.40
81 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23 56.24
82 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23 56.24
83 INT331229 Rasa1 Positive_regulation of Mtor 1 0.00 0.32 0 55.68
84 INT331233 Binding of Mtor and Rasa1 1 0.00 0.32 0 55.68
85 INT356284 Ptger2 Positive_regulation of Prkaca 1 0.00 0.39 0.37 55.52
86 INT157271 Adipor1 Positive_regulation of PRKAA1 1 0.01 0.89 0.08 54.72
87 INT323500 Ghrl Positive_regulation of Grb2 1 0.13 0.5 0 53.80
88 INT323495 Ghrl Positive_regulation of Irs1 1 0.20 0.5 0 53.80
89 INT323499 Ghrl Positive_regulation of Ins1 1 0.21 0.25 0 53.80
90 INT157272 Adipor1 Positive_regulation of APRT 1 0.12 0.88 0.07 53.68
91 INT244031 Binding of Gabrg2 and Nsf 1 0.04 0.19 0.05 53.36
92 INT244016 Binding of Nsf and Gabarap 1 0.07 0.19 0.05 53.36
93 INT329226 Negative_regulation of ATIC Positive_regulation of Psmd9 1 0.01 0.58 0.04 53.04
94 INT329229 ATIC Positive_regulation of Tpt1 1 0.01 0.58 0.04 53.04
95 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04 53.04
96 INT329231 ATIC Positive_regulation of Psmd9 1 0.01 0.58 0.04 53.04
97 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04 53.04
98 INT329227 Negative_regulation of ATIC Positive_regulation of Tpt1 1 0.01 0.58 0.04 53.04
99 INT331223 Negative_regulation of Tsc1 Positive_regulation of Positive_regulation of Mtor 1 0.01 0.33 0 51.80
100 INT222468 Nmb Positive_regulation of Localization of Trh 1 0.05 0.28 0.03 51.44
101 INT222510 Nmb Positive_regulation of Trh 1 0.05 0.28 0.03 51.44
102 INT244038 Binding of Gabrg2 and Gabarap 1 0.08 0.24 0.18 51.36
103 INT244048 Binding of Gabrg2 and Gabarapl1 1 0.02 0.19 0.05 51.36
104 INT257871 Binding of Ins1 and Positive_regulation of Trib3 1 0.01 0.49 0 50.76
105 INT244044 Binding of Gabarap and Gabarapl1 1 0.04 0.13 0.05 50.48
106 INT288214 Lep Negative_regulation of Gene_expression of Ins1 1 0.35 0.05 0 49.44
107 INT260841 Il6 Positive_regulation of Localization of NRP2 1 0.00 0.7 0.29 49.20
108 INT335013 Fgf21 Positive_regulation of Localization of Ins1 1 0.06 0.58 0 48.48
109 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52 46.96
110 INT301666 Binding of CYP4F2 and Ltb4r1 1 0.02 0.57 0.28 46.24
111 INT335012 Fgf21 Positive_regulation of Gene_expression of Ins1 1 0.06 0.57 0 45.12
112 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25 42.32
113 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25 42.32
114 INT327340 Binding of TNF and Hnrnpd 1 0.03 1.02 0.25 41.60
115 INT340552 Binding of Mapk1 and Mapk14 1 0.07 0.27 0.03 41.36
116 INT218733 Trh Positive_regulation of Gene_expression of Hdc 1 0.27 0 0.09 41.28
117 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25 41.20
118 INT337090 Mif Positive_regulation of Gene_expression of Mapk1 1 0.10 1.11 0.08 40.68
119 INT235313 Cyp3a23/3a1 Positive_regulation of Ins1 1 0.14 0.82 0.05 40.24
120 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 37.44
121 INT323492 Ins1 Regulation of Gene_expression of Pck1 1 0.08 0.16 0 37.44
122 INT335016 Fgf23 Negative_regulation of Gene_expression of Slc34a3 1 0.03 0.63 0.03 35.00
123 INT222487 Trh Negative_regulation of Nmb 1 0.05 0.26 0.05 34.00
124 INT331228 Atg5 Positive_regulation of Atg12 1 0.06 0.08 0 33.44
125 INT329222 Positive_regulation of Car2 Regulation of Camkk1 1 0.07 0.08 0.04 33.20
126 INT329220 Car2 Regulation of Camkk1 1 0.04 0.08 0.04 33.20
127 INT220459 Binding of FN1 and VEGFA 1 0.09 1.45 0.05 33.08
128 INT329219 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.04 0.93 0.05 32.64
129 INT331232 Binding of Atg12 and Atg16l1 1 0.03 0.08 0 29.44
130 INT331225 Binding of Atg5 and Atg16l1 1 0.05 0.08 0 29.20
131 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21 28.84
132 INT297854 Agrp Regulation of Pomc 1 0.24 0 0 26.64
133 INT307210 Ide Positive_regulation of Ppara 1 0.02 0.18 0 26.32
134 INT356275 Gdnf Positive_regulation of Phosphorylation of Mapk1 1 0.05 0.21 0.09 25.68
135 INT356277 Egf Positive_regulation of Phosphorylation of Mapk1 1 0.07 0.33 0.03 25.68
136 INT356280 Ngf Positive_regulation of Phosphorylation of Mapk1 1 0.05 0.33 0.03 25.68
137 INT307213 Srebf1 Regulation of Gene_expression of Fasn 1 0.05 0.06 0 24.88
138 INT244056 Nsf Regulation of Gabarap 1 0.05 0.09 0.24 20.36
139 INT244023 Nsf Regulation of Camk2a 1 0.04 0.09 0.24 20.36
140 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 17.60
141 INT244043 Binding of Gabrg1 and Ubqln1 1 0.03 0.26 0.59 14.84
142 INT244034 Binding of Gabrg2 and Ubqln1 1 0.01 0.09 0.26 14.84
143 INT244064 Binding of Gabpb1 and Ubqln1 1 0.00 0.09 0.26 14.84
144 INT316249 DBT Regulation of TRPM8 1 0.08 1.28 0.15 14.64
145 INT322206 CCL18 Positive_regulation of Gene_expression of COL7A1 1 0.05 0.28 0.05 13.60
146 INT306830 E2F2 Regulation of C1orf61 1 0.02 0.48 0.36 13.12
147 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12 8.88
148 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 8.88
149 INT307216 Ppara Regulation of Srebf1 1 0.22 0.12 0 5.68
150 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34 5.00
151 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
152 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 5.00
153 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 5.00
154 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 5.00
155 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
156 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86 5.00
157 INT9786 Gnrh1 Regulation of LH 7 0.40 0.58 1.82 5.00
158 INT207630 Binding of Calm3 and Nrgn 1 0.06 1.03 1.82 5.00
159 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47 5.00
160 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46 5.00
161 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3 5.00
162 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
163 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
164 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25 5.00
165 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2 5.00
166 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15 5.00
167 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 5.00
168 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
169 INT36186 Npy Positive_regulation of Localization of Gnrh1 4 0.75 0.09 0.96 5.00
170 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91 5.00
171 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9 5.00
172 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88 5.00
173 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85 5.00
174 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84 5.00
175 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 5.00
176 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83 5.00
177 INT201945 Binding of CXCR1 and CXCR2 3 0.14 0.84 0.8 5.00
178 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79 5.00
179 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75 5.00
180 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75 5.00
181 INT244062 Gabrg1 Regulation of Gabbr1 1 0.01 0.09 0.74 5.00
182 INT201941 IFNA1 Positive_regulation of Gene_expression of CXCL10 1 0.14 1.09 0.74 5.00
183 INT201947 IFNA1 Positive_regulation of Gene_expression of DPP4 1 0.11 1.09 0.74 5.00
184 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74 5.00
185 INT216668 Positive_regulation of NLRP1 Regulation of Vta1 1 0.00 0 0.73 5.00
186 INT337157 Iqgap1 Regulation of Gene_expression of Ros1 1 0.07 1.91 0.72 5.00
187 INT244025 Prkaca Regulation of Phosphorylation of Gabrg1 1 0.08 0.18 0.72 5.00
188 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72 5.00
189 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71 5.00
190 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71 5.00
191 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7 5.00
192 INT32715 Prl Regulation of Localization of LH 2 0.34 0.09 0.68 5.00
193 INT60283 Positive_regulation of Gnrh1 Regulation of LH 2 0.31 0 0.68 5.00
194 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67 5.00
195 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66 5.00
196 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65 5.00
197 INT309663 Binding of Cia1 and Aia1 1 0.00 1.31 0.64 5.00
198 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64 5.00
199 INT295705 Binding of IK and TNF 1 0.00 0.27 0.64 5.00
200 INT222492 Ngf Positive_regulation of Gene_expression of Prl 1 0.24 0 0.62 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Starvation. They are ordered first by their pain relevance and then by number of times they were reported in Starvation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 100.00
2 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
3 INT297830 Positive_regulation of Snord116 1 0.49 0.96 0 100.00
4 INT301603 Negative_regulation of Gene_expression of CYP4F3 1 0.33 0.66 0.32 100.00
5 INT126477 Gene_expression of Sdf2l1 43 0.66 22.02 3.97 100.00
6 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
7 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 100.00
8 INT22404 Regulation of DBI 7 0.39 3.66 2.24 100.00
9 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.98
10 INT50272 Positive_regulation of Cotl1 24 0.40 6.57 2.77 99.98
11 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 99.98
12 INT18444 Positive_regulation of Negative_regulation of ADRA2C 1 0.42 0.61 0.19 99.98
13 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.96
14 INT151588 Phosphorylation of Prkag1 48 0.73 15.62 1.38 99.96
15 INT5511 Negative_regulation of Gene_expression of Pomc 47 0.59 12.08 23.02 99.90
16 INT271943 Phosphorylation of Tsc2 9 0.52 3.35 0.13 99.86
17 INT252054 Phosphorylation of TSC2 4 0.80 0.63 0.67 99.86
18 INT403 Localization of Trh 241 0.81 28.55 81.45 99.80
19 INT154937 Positive_regulation of MAP1LC3A 4 0.60 4.42 2.1 99.80
20 INT14419 Negative_regulation of Localization of Trh 40 0.59 2.04 17.42 99.80
21 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 99.80
22 INT26282 Negative_regulation of ELN 9 0.51 6.37 3.76 99.80
23 INT150105 Positive_regulation of Gene_expression of Pdk4 2 0.41 2.96 0.12 99.78
24 INT18442 Negative_regulation of ADRA2C 2 0.49 0.61 0.51 99.78
25 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24 99.74
26 INT297803 Negative_regulation of Gene_expression of Snx1 1 0.53 0.61 0.09 99.72
27 INT297770 Negative_regulation of Gene_expression of Snx6 1 0.49 0.32 0.05 99.72
28 INT297840 Negative_regulation of Gene_expression of Snx5 1 0.36 0.32 0.05 99.72
29 INT297782 Negative_regulation of Gene_expression of Snx2 1 0.35 0.32 0.05 99.72
30 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 99.68
31 INT892 Regulation of TRH 23 0.60 8.46 8.54 99.68
32 INT297835 Regulation of Pdk4 1 0.40 0.57 0 99.64
33 INT197173 Positive_regulation of Cyp4a10 29 0.62 15.68 1.61 99.60
34 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.60
35 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 99.60
36 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 99.58
37 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.52
38 INT244959 Gene_expression of Snx1 5 0.70 3.22 0.22 99.52
39 INT297761 Gene_expression of Snx6 1 0.65 0.32 0.05 99.52
40 INT297779 Gene_expression of Snx5 1 0.66 0.32 0.05 99.52
41 INT244967 Gene_expression of Snx2 4 0.64 0.48 0.05 99.52
42 INT301208 Gene_expression of Mir29a 1 0.17 26.18 0 99.48
43 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5 99.48
44 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.48
45 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.44
46 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 99.44
47 INT189565 Positive_regulation of Transcription of PDK4 2 0.48 0.52 0.12 99.44
48 INT44636 Negative_regulation of Pgpep1 2 0.38 1.8 0.19 99.42
49 INT150109 Gene_expression of Pdk4 2 0.53 3.79 0.12 99.40
50 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 99.40
51 INT331194 Negative_regulation of Ulk1 1 0.14 0.1 0 99.36
52 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 99.34
53 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 99.34
54 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34 99.32
55 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 99.32
56 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38 99.32
57 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75 99.32
58 INT162124 Positive_regulation of Phosphorylation of Egf 3 0.45 0.77 1.14 99.32
59 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 99.32
60 INT132411 Positive_regulation of Ghrl 25 0.69 12.05 2.59 99.26
61 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.20
62 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 99.18
63 INT331196 Positive_regulation of Phosphorylation of Atg13 1 0.14 0.25 0 99.18
64 INT306665 Positive_regulation of Phosphorylation of Ulk1 3 0.23 0.58 0 99.18
65 INT189569 Transcription of PDK4 2 0.68 0.52 0.12 99.16
66 INT59532 Negative_regulation of Transcription of Trh 2 0.18 0.4 0.59 99.12
67 INT77636 Phosphorylation of Egf 11 0.61 1.69 2.56 99.12
68 INT243934 Protein_catabolism of Fibp 2 0.01 0.63 0.04 99.12
69 INT243948 Regulation of Protein_catabolism of Fibp 1 0.00 0.26 0.04 99.12
70 INT197166 Gene_expression of Cyp4a10 27 0.75 15.63 1.81 99.08
71 INT197174 Positive_regulation of Gene_expression of Cyp4a10 17 0.67 8.65 1.4 99.08
72 INT224966 Positive_regulation of Gene_expression of Snord116 3 0.50 1.72 0.17 99.08
73 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03 99.08
74 INT141936 Phosphorylation of Mapt 14 0.80 10.59 0.95 99.08
75 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 99.06
76 INT254886 Positive_regulation of Fasn 2 0.06 0.94 0.31 99.06
77 INT220047 Negative_regulation of Gene_expression of Mmp3 4 0.29 5.93 3.95 99.02
78 INT116281 Negative_regulation of Gene_expression of Mmp13 15 0.41 9.96 3.41 99.02
79 INT164260 Positive_regulation of Gene_expression of H19 2 0.67 4.29 0.43 99.00
80 INT331182 Phosphorylation of Atg13 1 0.23 0.25 0 99.00
81 INT306672 Phosphorylation of Ulk1 5 0.27 0.88 0 99.00
82 INT306668 Negative_regulation of Phosphorylation of Ulk1 2 0.14 0.27 0 99.00
83 INT331191 Negative_regulation of Phosphorylation of Atg13 1 0.12 0.1 0 99.00
84 INT173752 Positive_regulation of Ghr 3 0.57 2.21 0.41 98.96
85 INT157309 Regulation of MAP1LC3A 2 0.44 1.49 0.4 98.88
86 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05 98.88
87 INT86246 Binding of Bcl2l1 8 0.37 6.67 0.57 98.88
88 INT123521 Phosphorylation of Bcl2 8 0.81 5 0 98.88
89 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 98.86
90 INT7923 Transcription of Trh 14 0.72 4.44 6.32 98.82
91 INT297806 Regulation of Stra8 1 0.39 0.59 0 98.72
92 INT297825 Regulation of Dnmt3l 1 0.39 0.59 0 98.72
93 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 98.72
94 INT224953 Gene_expression of Snord116 23 0.78 9.86 0.89 98.68
95 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 98.68
96 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 98.68
97 INT331192 Negative_regulation of Atg13 1 0.12 0.1 0 98.64
98 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 98.62
99 INT19008 Positive_regulation of Positive_regulation of Ghrh 15 0.49 2.4 4.55 98.58
100 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03 98.58
101 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 98.58
102 INT211807 Binding of PTBP1 11 0.31 6.09 0.45 98.56
103 INT97892 Positive_regulation of Gene_expression of Ghrl 31 0.49 13.43 1.7 98.56
104 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 98.52
105 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23 98.52
106 INT216662 Regulation of Gene_expression of P2ry1 1 0.24 0.2 0.63 98.50
107 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 98.48
108 INT1045 Localization of LH 1211 0.81 87.04 456.25 98.48
109 INT11590 Regulation of Negative_regulation of LH 10 0.39 2.02 4.25 98.48
110 INT268791 Positive_regulation of Protein_catabolism of Ghr 1 0.39 0.29 0.09 98.46
111 INT164259 Gene_expression of H19 8 0.75 27.5 0.97 98.40
112 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4 98.40
113 INT179101 Gene_expression of CYP4F3 14 0.65 6.89 1.98 98.40
114 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21 98.36
115 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 98.32
116 INT106960 Gene_expression of Chrm3 15 0.69 6.29 0.96 98.30
117 INT876 Localization of Gh1 843 0.80 67.75 340.82 98.28
118 INT282990 Negative_regulation of Binding of Becn1 6 0.08 1.44 0 98.28
119 INT268793 Protein_catabolism of Ghr 1 0.69 0.54 0.12 98.26
120 INT6852 Localization of TNF 883 0.81 705.95 270.84 98.24
121 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84 98.20
122 INT93122 Gene_expression of P2ry1 32 0.75 11.82 11.42 98.20
123 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 98.20
124 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97 98.08
125 INT172855 Binding of Bcl2 37 0.32 23.41 1.09 98.08
126 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 98.08
127 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 98.08
128 INT150677 Negative_regulation of Eif2ak3 9 0.58 6.24 1.46 98.08
129 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61 98.04
130 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 98.00
131 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04 98.00
132 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 98.00
133 INT5489 Localization of CA2 172 0.80 39.46 33.56 98.00
134 INT282974 Binding of Becn1 24 0.07 7.43 0 97.98
135 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 97.96
136 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1 97.88
137 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98 97.88
138 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 97.64
139 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 97.64
140 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 97.64
141 INT7366 Negative_regulation of Ghrh 42 0.58 7.72 14.45 97.60
142 INT301228 Positive_regulation of Gene_expression of Mir29a 1 0.16 13.38 0 97.60
143 INT325179 Positive_regulation of SCYL1 1 0.00 0.78 0 97.50
144 INT18443 Positive_regulation of ADRA2C 12 0.69 2.61 5.48 97.44
145 INT14130 Regulation of ADRA2C 4 0.45 1.57 0.79 97.44
146 INT14513 Localization of Ghrl 52 0.78 29.26 11.63 97.40
147 INT97891 Gene_expression of Ghrl 108 0.77 24.85 9.7 97.40
148 INT3323 Gene_expression of ALAS2 10 0.58 7.51 0.21 97.36
149 INT3322 Positive_regulation of Gene_expression of ALAS2 4 0.43 3.25 0 97.36
150 INT42971 Binding of Hivep3 14 0.42 3.92 8.99 97.36
151 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 97.28
152 INT47563 Negative_regulation of Negative_regulation of Gh1 3 0.41 0.7 0.64 97.26
153 INT289045 Positive_regulation of Gene_expression of Sat1 1 0.41 0.18 0.13 97.06
154 INT289042 Positive_regulation of Sat1 1 0.41 0.17 0.13 97.06
155 INT297788 Gene_expression of Nanos2 1 0.59 4.02 0 96.92
156 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98 96.92
157 INT122041 Binding of Ppara 308 0.48 189.17 51.48 96.92
158 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06 96.92
159 INT289038 Gene_expression of Sat1 1 0.64 0.32 0.19 96.80
160 INT220466 Regulation of BAG6 1 0.04 1.58 0 96.80
161 INT224963 Gene_expression of Pdia6 6 0.22 4.51 0.28 96.72
162 INT297834 Negative_regulation of Gene_expression of Pdia6 1 0.10 1.27 0.03 96.72
163 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0 96.64
164 INT297791 Transcription of Fzd4 1 0.06 0.58 0 96.64
165 INT297757 Transcription of Lrp5 2 0.68 0.82 0 96.64
166 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 96.56
167 INT61075 Gene_expression of PMP2 23 0.61 7.42 2.79 96.56
168 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86 96.52
169 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07 96.52
170 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 96.44
171 INT195145 Positive_regulation of Gene_expression of CA2 25 0.37 7.2 6.59 96.44
172 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 96.42
173 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 96.36
174 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 96.36
175 INT254873 Regulation of Map1lc3a 5 0.58 1.24 0.03 96.24
176 INT331200 Regulation of Atg4a 1 0.01 0.39 0 96.24
177 INT121125 Gene_expression of IGKV1-32 1 0.03 1.05 0.22 96.16
178 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 96.08
179 INT259062 Binding of HPV18I1 2 0.01 3.78 0.09 96.08
180 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 96.04
181 INT163581 Localization of Lep 27 0.79 18.99 4.08 96.04
182 INT297790 Gene_expression of Brms1l 1 0.58 2.66 0.03 96.00
183 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 96.00
184 INT297777 Negative_regulation of Gene_expression of Brms1l 1 0.37 1.32 0.03 96.00
185 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91 96.00
186 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59 96.00
187 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25 95.88
188 INT261142 Negative_regulation of HPV18I1 1 0.01 5.66 0.17 95.84
189 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 95.84
190 INT254881 Negative_regulation of Atg7 9 0.34 5.69 0.32 95.56
191 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 95.44
192 INT102745 Positive_regulation of Hmbs 17 0.61 12.41 0.78 95.36
193 INT3535 Regulation of CA2 61 0.32 16.48 10.8 95.28
194 INT157305 Gene_expression of Map1lc3a 47 0.75 18.04 1.93 95.24
195 INT301524 Negative_regulation of Binding of Cyp4a10 1 0.33 1.21 0.09 95.24
196 INT29904 Negative_regulation of Binding of Scn4a 4 0.41 1.21 1.56 95.24
197 INT165481 Negative_regulation of Gene_expression of Map1lc3a 7 0.45 2.55 0.14 95.24
198 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27 95.20
199 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72 95.12
200 INT103094 Binding of PPARA 308 0.47 177.26 34.75 95.12
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