D:Stiff-person Syndrome

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pChart

Disease Term
Synonyms Moersch Woltmann Syndrome, Stiff Man Syndrome, Stiff Person Syndrome, STIFFMAN SYNDROME, Syndrome Moersch Woltmann, Syndrome Stiff Man, Syndrome Stiff Person, Syndrome Stiffman
Documents 32
Hot Single Events 27
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Stiff-person Syndrome. They are ordered first by their relevance to Stiff-person Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT180252 Negative_regulation of Gad1 Positive_regulation of CP 1 0.03 0.75 0.14 12.72
2 INT180245 Binding of Plp1 and Uchl1 1 0.03 0.47 0.27 5.00
3 INT180246 Binding of Tbca and Uchl1 1 0.00 0.47 0.27 5.00
4 INT180247 Binding of Gad1 and Tbca 1 0.02 0.22 0.22 5.00
5 INT180248 Binding of Gad1 and Plp1 1 0.08 0.22 0.21 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Stiff-person Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Stiff-person Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT105618 Binding of SEPHS1 4 0.27 5.62 1.14 100.00
2 INT245648 Gene_expression of SEPHS1 5 0.49 4.53 0.59 100.00
3 INT153782 Localization of SEPHS1 2 0.62 0.9 0.12 100.00
4 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 99.90
5 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 97.98
6 INT90567 Negative_regulation of Gene_expression of Gad1 4 0.41 2.88 1.36 95.12
7 INT180239 Negative_regulation of Gene_expression of Gad2 2 0.42 1.59 0.55 95.12
8 INT22143 Gene_expression of Gad1 35 0.76 14.4 15.4 94.48
9 INT96637 Gene_expression of Gad2 21 0.76 8.15 9.53 94.48
10 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 93.48
11 INT36148 Binding of GAD1 10 0.41 7.91 1.47 92.80
12 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 92.32
13 INT9516 Negative_regulation of Gabrg1 149 0.53 27.83 91.02 91.48
14 INT48687 Gene_expression of Plp1 7 0.54 3.51 1.03 90.32
15 INT180234 Negative_regulation of Gene_expression of Plp1 1 0.08 1.54 0.42 90.32
16 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 90.00
17 INT180238 Regulation of Gene_expression of Twist1 13 0.61 4.87 1.59 90.00
18 INT25394 Negative_regulation of Gene_expression of Csf2 22 0.52 13.18 5.84 89.20
19 INT180250 Positive_regulation of GLUL 23 0.29 7.57 3.23 88.00
20 INT173336 Gene_expression of GLUL 16 0.27 6.74 2.78 88.00
21 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 86.16
22 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36 86.16
23 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 86.16
24 INT16427 Negative_regulation of Positive_regulation of Csf2 2 0.43 1.5 1.2 86.16
25 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 84.16
26 INT28314 Negative_regulation of Gene_expression of Gabrg1 29 0.44 12.56 13.8 84.16
27 INT49212 Negative_regulation of GAD1 23 0.59 22.15 6.54 83.04
28 INT180236 Binding of Etv5 2 0.36 1.09 0.18 79.36
29 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 71.60
30 INT116540 Binding of Twist1 35 0.48 16.32 2.85 71.60
31 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 50.00
32 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 50.00
33 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97 50.00
34 INT309915 Negative_regulation of F2RL3 2 0.01 2.06 0.27 50.00
35 INT309916 Negative_regulation of NR2F2 1 0.02 0.7 0.18 50.00
36 INT6034 Binding of Gabrg1 115 0.47 17.48 51.92 46.72
37 INT159645 Negative_regulation of Uchl1 8 0.31 6.84 2.14 30.84
38 INT42255 Negative_regulation of Gad1 7 0.56 4.83 2.54 10.96
39 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 5.00
40 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 5.00
41 INT39587 Gene_expression of CP 42 0.65 31.48 11.87 5.00
42 INT75932 Binding of Csf2 45 0.37 33.2 8.01 5.00
43 INT28315 Regulation of Gene_expression of Gabrg1 20 0.60 4.78 7 5.00
44 INT3309 Binding of CP 25 0.47 17.87 6.62 5.00
45 INT42251 Regulation of Gad1 10 0.44 5.25 3.45 5.00
46 INT70596 Regulation of Uchl1 5 0.39 3.87 3.11 5.00
47 INT165514 Regulation of Gad2 7 0.45 3.15 2.76 5.00
48 INT8466 Binding of Plp1 5 0.48 5.07 2.29 5.00
49 INT42256 Positive_regulation of Gad1 4 0.66 1.1 2.09 5.00
50 INT96642 Transcription of Gad2 4 0.59 0.88 1.59 5.00
51 INT180249 Negative_regulation of GLUL 5 0.15 0.69 1.46 5.00
52 INT51591 Regulation of GLUL 3 0.11 2.62 1.15 5.00
53 INT90568 Regulation of Gene_expression of Gad1 3 0.27 0.46 0.89 5.00
54 INT180240 Binding of Gad1 7 0.47 2.99 0.86 5.00
55 INT39586 Transcription of CP 5 0.67 1.7 0.83 5.00
56 INT95699 Binding of Gad2 5 0.40 1.14 0.73 5.00
57 INT180244 Positive_regulation of Gad2 4 0.49 1.07 0.61 5.00
58 INT162843 Negative_regulation of Gene_expression of CP 2 0.11 2.79 0.45 5.00
59 INT180242 Positive_regulation of Binding of Gad1 1 0.49 0.86 0.17 5.00
60 INT180237 Binding of Tbca 2 0.03 1.08 0.15 5.00
61 INT180233 Negative_regulation of Negative_regulation of Uchl1 1 0.14 0.6 0.14 5.00
62 INT180243 Phosphorylation of Gad2 1 0.52 0.48 0.06 5.00
63 INT180241 Positive_regulation of Binding of Gad2 1 0.39 0.29 0.03 5.00
64 INT180232 Protein_catabolism of Gad1 1 0.87 0.52 0 5.00
65 INT180251 Gene_expression of ERCC4 1 0.65 0 0 5.00
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