D:Stomach Disease

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Disease Term
Synonyms Disease Gastric, Disease Stomach, DISEASES GASTRIC, Diseases Stomach, Gastric Disease, GASTRIC DISEASES, Stomach Diseases, Stomach Disorder, Stomach Disorders, Stomach Dysfunction, Stomach Function Disorder
Documents 104
Hot Single Events 18
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Stomach Disease. They are ordered first by their relevance to Stomach Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15 91.60
2 INT179872 Binding of HGF and MET 7 0.09 4.69 0.07 57.68
3 INT185756 Binding of ITIH4 and Cd4 2 0.05 1.22 0.04 18.80
4 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18 5.00
5 INT266616 Il4 Positive_regulation of Il12a 1 0.01 0.4 0.17 5.00
6 INT336030 PGE Regulation of Gene_expression of Cpox 1 0.05 0.22 0.07 5.00
7 INT336032 tf Positive_regulation of Gene_expression of Cpox 1 0.05 0.09 0.05 5.00
8 INT336031 tf Positive_regulation of Gene_expression of PGE 1 0.12 0.09 0.05 5.00
9 INT212442 HGF Positive_regulation of MET 2 0.21 1.25 0.04 5.00
10 INT266617 Binding of GJC1 and Tjp1 1 0.41 0.28 0.03 5.00
11 INT285580 Binding of PTPN11 and S100A8 1 0.05 0.2 0 5.00
12 INT225898 Positive_regulation of RAC1 Positive_regulation of PAK1 1 0.01 0.08 0 5.00
13 INT225909 Binding of GRB2 and SOS1 1 0.01 0.11 0 5.00
14 INT285579 Binding of S100A8 and SRC 1 0.05 0.2 0 5.00
15 INT225892 Binding of GAB1 and RASA1 1 0.01 0.06 0 5.00
16 INT225889 Binding of MET and SHC1 1 0.01 0 0 5.00
17 INT225887 HGF Positive_regulation of ATF2 1 0.01 0 0 5.00
18 INT225905 Binding of GRB2 and SHC1 1 0.00 0 0 5.00
19 INT225870 Binding of CRKL and Cbl 1 0.00 0 0 5.00
20 INT271717 Binding of Fut4 and Tlr4 1 0.01 0.3 0 5.00
21 INT225906 Binding of GAB1 and GRB2 1 0.01 0.27 0 5.00
22 INT225908 Binding of RAC1 and IQGAP1 1 0.00 0.09 0 5.00
23 INT225890 Binding of RAC1 and STAT3 1 0.01 0 0 5.00
24 INT225873 Ilk Positive_regulation of AKT1 1 0.00 0.07 0 5.00
25 INT225903 Binding of GAB1 and PIK3CG 1 0.01 0.13 0 5.00
26 INT225896 HGF Positive_regulation of STAT3 1 0.01 0 0 5.00
27 INT225876 PIK3CG Positive_regulation of Ilk 1 0.00 0 0 5.00
28 INT225902 Binding of CRKL and GAB1 1 0.01 0.1 0 5.00
29 INT225874 Positive_regulation of ras Positive_regulation of RAF1 1 0.00 0 0 5.00
30 INT285581 Binding of CSK and S100A8 1 0.09 0.2 0 5.00
31 INT225871 RAF1 Positive_regulation of Mdk 1 0.00 0 0 5.00
32 INT225895 Binding of CRK and GAB1 1 0.01 0.1 0 5.00
33 INT225897 PDPK1 Positive_regulation of AKT1 1 0.01 0.07 0 5.00
34 INT285582 Binding of ABL1 and S100A8 1 0.02 0.2 0 5.00
35 INT225891 DOCK1 Positive_regulation of RAC1 1 0.01 0 0 5.00
36 INT225872 Binding of CRK and Cbl 1 0.00 0 0 5.00
37 INT225875 ras Positive_regulation of RAF1 1 0.00 0 0 5.00
38 INT225894 Binding of MET and PIK3CG 1 0.00 0.13 0 5.00
39 INT225893 Binding of CRKL and DOCK1 1 0.01 0 0 5.00
40 INT225900 Binding of GAB1 and MET 1 0.00 0.26 0 5.00
41 INT225899 Binding of DOCK1 and RAC1 1 0.01 0 0 5.00
42 INT225907 Binding of CRK and DOCK1 1 0.01 0 0 5.00
43 INT225888 AKT1 Positive_regulation of PAK1 1 0.01 0.08 0 5.00
44 INT225904 Binding of GAB1 and PIK3CA 1 0.07 0.06 0 5.00
45 INT225901 Binding of GRB2 and MET 1 0.00 0.33 0 5.00
46 INT223734 Binding of VEGFA and Nos2 1 0.01 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Stomach Disease. They are ordered first by their pain relevance and then by number of times they were reported in Stomach Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2541 Binding of Calca 200 0.48 67.14 134.62 99.80
2 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 99.80
3 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.56
4 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.42
5 INT219113 Localization of ALKBH1 1 0.07 1.21 0.09 95.68
6 INT233 Binding of Gast 31 0.42 17.07 5.21 91.52
7 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 89.40
8 INT90 Localization of Gast 400 0.81 137.67 113 89.12
9 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 89.08
10 INT36382 Binding of FUT4 13 0.36 4.13 0.34 88.68
11 INT12339 Localization of IL8 437 0.81 251.87 117.39 87.76
12 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 87.76
13 INT140053 Positive_regulation of Cish 9 0.41 2.4 2 84.92
14 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 84.28
15 INT91 Positive_regulation of Localization of Gast 96 0.70 23.22 29.36 82.24
16 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98 80.84
17 INT86708 Negative_regulation of SUMO1 3 0.18 1.71 0.28 80.24
18 INT86709 Positive_regulation of SUMO1 3 0.19 2.59 0.24 80.24
19 INT42057 Negative_regulation of SAA2 2 0.01 1.22 0.41 78.92
20 INT28 Regulation of Gast 106 0.62 26.37 29.85 76.88
21 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 76.40
22 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 76.16
23 INT37193 Negative_regulation of BDNF-AS 21 0.37 15.06 3.12 75.00
24 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 75.00
25 INT286891 Positive_regulation of Gene_expression of Spir1 1 0.06 0.89 0.14 75.00
26 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 73.36
27 INT215107 Gene_expression of Spir1 17 0.50 10.38 0.25 73.28
28 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 69.48
29 INT142201 Positive_regulation of Localization of S100A8 2 0.49 1.21 0.31 64.44
30 INT60942 Localization of S100A8 12 0.78 12.23 2.39 63.76
31 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14 58.08
32 INT219083 Binding of Sle10 1 0.35 0.8 0 58.08
33 INT12464 Binding of MET 38 0.47 10.3 13.15 57.68
34 INT62711 Binding of HGF 27 0.31 15.23 2.08 57.68
35 INT13822 Localization of Egf 30 0.81 13.79 6.4 48.12
36 INT232806 Localization of Tff1 1 0.24 1.39 0 48.12
37 INT7980 Gene_expression of Fut4 36 0.62 13.37 3.79 43.48
38 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 43.00
39 INT271691 Gene_expression of Insl3 1 0.01 4.95 0 42.76
40 INT171117 Binding of Itgam 35 0.36 14.87 2.76 42.44
41 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 42.00
42 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 40.88
43 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 36.20
44 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25 34.44
45 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 32.60
46 INT86584 Phosphorylation of S100A8 10 0.80 4.99 0.41 32.56
47 INT18920 Binding of Egf 24 0.48 9.43 3.57 24.84
48 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 23.44
49 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7 17.28
50 INT4977 Binding of ITIH4 60 0.46 42.48 15.65 17.28
51 INT88317 Negative_regulation of Binding of ITIH4 6 0.36 4.46 0.69 17.28
52 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 15.52
53 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64 15.52
54 INT65926 Positive_regulation of Gene_expression of Egf 26 0.70 12.91 4.18 15.52
55 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77 15.52
56 INT66725 Binding of Rars 6 0.48 8.7 1 15.52
57 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 15.04
58 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12 15.04
59 INT219107 Gene_expression of ALKBH1 1 0.07 1.05 0.07 12.24
60 INT91158 Regulation of Ros1 26 0.25 17 4.23 12.16
61 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
62 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
63 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
64 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
65 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
66 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 5.00
67 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
68 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
69 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 5.00
70 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
71 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
72 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
73 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 5.00
74 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
75 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 5.00
76 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
77 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
78 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
79 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
80 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
81 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
82 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 5.00
83 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
84 INT3920 Localization of Ldha 241 0.81 83.08 58.72 5.00
85 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 5.00
86 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 5.00
87 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 5.00
88 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21 5.00
89 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
90 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 5.00
91 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 5.00
92 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
93 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 5.00
94 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72 5.00
95 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 5.00
96 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 5.00
97 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
98 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85 5.00
99 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 5.00
100 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 5.00
101 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31 5.00
102 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
103 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 5.00
104 INT23224 Gene_expression of tf 99 0.56 60.22 22.03 5.00
105 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
106 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22 5.00
107 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89 5.00
108 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 5.00
109 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 5.00
110 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 5.00
111 INT61949 Regulation of Nos2 74 0.58 34.08 16.7 5.00
112 INT1214 Gene_expression of PGE 70 0.72 29.07 16.22 5.00
113 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67 5.00
114 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 5.00
115 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21 5.00
116 INT39733 Localization of NFKB1 59 0.79 22.76 13.99 5.00
117 INT3174 Negative_regulation of Ptger2 43 0.38 20.95 13.43 5.00
118 INT12156 Positive_regulation of MET 43 0.67 17.75 12.64 5.00
119 INT12191 Negative_regulation of Localization of Ldha 35 0.59 13.71 12.35 5.00
120 INT83611 Negative_regulation of Gene_expression of Cpox 55 0.29 31.09 11.5 5.00
121 INT14334 Negative_regulation of Il2 31 0.58 18.63 11.08 5.00
122 INT94004 Negative_regulation of Lox 31 0.59 13.76 10.45 5.00
123 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23 5.00
124 INT18258 Negative_regulation of Thop1 20 0.56 1.6 8.61 5.00
125 INT191765 Regulation of CALM1 15 0.52 9.52 8.56 5.00
126 INT87434 Gene_expression of Sell 38 0.77 21.95 8.51 5.00
127 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 5.00
128 INT130117 Regulation of Per1 26 0.53 3.25 7.63 5.00
129 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26 5.00
130 INT144945 Negative_regulation of Icam1 27 0.50 26.23 7.08 5.00
131 INT9397 Regulation of MET 17 0.60 8.36 7.04 5.00
132 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74 5.00
133 INT8101 Binding of INCENP 42 0.31 16.2 6.68 5.00
134 INT27325 Positive_regulation of Pyy 15 0.62 13.69 6.54 5.00
135 INT77945 Regulation of Gene_expression of Il12a 19 0.58 6.55 6.4 5.00
136 INT86805 Localization of HGF 49 0.71 28.48 6.35 5.00
137 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95 5.00
138 INT26919 Gene_expression of ITPR3 47 0.42 5.86 5.79 5.00
139 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 5.00
140 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71 5.00
141 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61 5.00
142 INT5317 Positive_regulation of PGE 24 0.46 8.27 5.49 5.00
143 INT89142 Gene_expression of Lox 28 0.67 15.36 5.2 5.00
144 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79 5.00
145 INT90350 Gene_expression of Gast 27 0.78 14.07 4.74 5.00
146 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62 5.00
147 INT57592 Negative_regulation of TAs 17 0.33 9.49 4.51 5.00
148 INT24278 Gene_expression of FUT4 33 0.75 26.7 4.29 5.00
149 INT48518 Gene_expression of ANPEP 51 0.78 22.88 4.18 5.00
150 INT34085 Negative_regulation of Gene_expression of PGE 16 0.35 4.9 3.76 5.00
151 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75 5.00
152 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71 5.00
153 INT121818 Binding of STAT3 25 0.47 11.16 3.67 5.00
154 INT25386 Positive_regulation of Cd3e 30 0.62 13.91 3.41 5.00
155 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32 5.00
156 INT134786 Gene_expression of Adam10 17 0.68 7.61 3.29 5.00
157 INT185738 Binding of Cd14 28 0.45 14.41 3.25 5.00
158 INT62112 Binding of S100A8 37 0.36 17.18 3.16 5.00
159 INT104902 Regulation of ASIC1 6 0.51 5.17 3.13 5.00
160 INT2405 Negative_regulation of SGCA 15 0.57 6.04 2.45 5.00
161 INT183668 Binding of SGCA 15 0.36 9.86 2.42 5.00
162 INT114327 Positive_regulation of RAF1 26 0.51 20.87 2.32 5.00
163 INT160673 Gene_expression of Ambp 16 0.49 19.49 2.3 5.00
164 INT94002 Regulation of Lox 13 0.38 8.41 2.29 5.00
165 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 5.00
166 INT70987 Binding of RAC1 14 0.37 12.14 2.13 5.00
167 INT149031 Gene_expression of Tjp1 43 0.75 19.1 2.06 5.00
168 INT94001 Positive_regulation of Lox 15 0.60 7.46 1.92 5.00
169 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92 5.00
170 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74 5.00
171 INT12442 Localization of Vegfa 11 0.73 4.85 1.68 5.00
172 INT1215 Negative_regulation of PGE 19 0.47 4.6 1.52 5.00
173 INT46736 Negative_regulation of Odc1 10 0.51 7.6 1.39 5.00
174 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38 5.00
175 INT27656 Gene_expression of Tgfa 6 0.74 3.37 1.32 5.00
176 INT75746 Regulation of ZMYND10 3 0.44 0.5 1.31 5.00
177 INT51817 Gene_expression of Pyy 5 0.65 1.4 1.25 5.00
178 INT130207 Phosphorylation of ATF2 5 0.60 1.34 1.25 5.00
179 INT175520 Gene_expression of Igf2 43 0.78 48.93 1.21 5.00
180 INT102615 Positive_regulation of Gene_expression of Tgfa 5 0.44 3.93 1.17 5.00
181 INT219108 Negative_regulation of Gene_expression of MUC5AC 11 0.31 9.74 1.08 5.00
182 INT233561 Gene_expression of Clu 14 0.66 45.63 1.07 5.00
183 INT70209 Negative_regulation of FYN 3 0.08 1.07 1.06 5.00
184 INT112677 Localization of tf 20 0.48 9.66 1.06 5.00
185 INT235939 Gene_expression of Aqp5 8 0.45 4.7 1.06 5.00
186 INT30041 Binding of HAL 8 0.35 2.36 0.95 5.00
187 INT173021 Localization of MUC5AC 14 0.70 10.73 0.91 5.00
188 INT90351 Negative_regulation of Gast 5 0.59 2.85 0.89 5.00
189 INT113815 Gene_expression of TFF1 23 0.75 17.53 0.87 5.00
190 INT184418 Negative_regulation of Positive_regulation of GOPC 15 0.26 5.47 0.87 5.00
191 INT143912 Localization of Src 4 0.48 2.51 0.78 5.00
192 INT17227 Gene_expression of 16S 11 0.75 2.65 0.76 5.00
193 INT109983 Positive_regulation of Hspb1 7 0.66 6.66 0.72 5.00
194 INT24041 Gene_expression of SNRPA1 5 0.75 8.39 0.71 5.00
195 INT129756 Regulation of MUC5AC 7 0.34 6.45 0.7 5.00
196 INT148564 Localization of HAL 8 0.68 2.46 0.62 5.00
197 INT147734 Phosphorylation of RAC1 3 0.64 1.33 0.58 5.00
198 INT78499 Binding of tf 8 0.22 2.64 0.55 5.00
199 INT132781 Phosphorylation of PIK3CG 8 0.52 4.83 0.53 5.00
200 INT124614 Transcription of ANPEP 3 0.52 1.1 0.51 5.00
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