D:Streptococcal Infections

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Disease Term
Synonyms Infection Streptococcal, Infections Streptococcal, Streptococcal Infection
Documents 145
Hot Single Events 19
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Streptococcal Infections. They are ordered first by their relevance to Streptococcal Infections and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT337072 Binding of Fmr1 and Gusb 1 0.19 1.55 0.08 90.88
2 INT64242 Binding of Gast and TSS 1 0.08 1.73 0.09 75.00
3 INT180164 Gast Positive_regulation of Nfasc 1 0.02 1.31 0 32.16
4 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
5 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
6 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
7 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
8 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86 5.00
9 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12 5.00
10 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 5.00
11 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84 5.00
12 INT186123 Binding of GIF and IL10 1 0.23 1.17 0.69 5.00
13 INT282505 Binding of ocd and Slc1a1 1 0.39 4.22 0.4 5.00
14 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32 5.00
15 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 0.01 0.6 0.27 5.00
16 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
17 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
18 INT313273 Binding of GRIN1 and MAP2 1 0.16 0.79 0.04 5.00
19 INT282503 Binding of ocd and Dlgap3 1 0.28 1.58 0.03 5.00
20 INT260811 Binding of ITGA4 and ITGAL 1 0.02 0 0.03 5.00
21 INT252020 Binding of HLA-A and ELOVL1 1 0.01 1.41 0 5.00
22 INT282504 Binding of Grik2 and Grik3 1 0.27 0.61 0 5.00
23 INT282507 Binding of Grik3 and ocd 1 0.25 0.61 0 5.00
24 INT313271 Binding of GRIN1 and GRIN2B 1 0.24 0.06 0 5.00
25 INT313272 Binding of DLG4 and GRIN1 1 0.09 0.06 0 5.00
26 INT282502 Negative_regulation of Binding of ocd and Slc1a1 1 0.30 0.48 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Streptococcal Infections. They are ordered first by their pain relevance and then by number of times they were reported in Streptococcal Infections. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4075 Positive_regulation of Gene_expression of Gast 24 0.68 19.99 4.02 99.08
2 INT30 Gene_expression of Gast 158 0.78 99 41.45 98.72
3 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63 98.56
4 INT20982 Positive_regulation of SERPINB1 7 0.28 7.27 1.61 98.24
5 INT92769 Positive_regulation of Arsk 1 0.05 2.16 0.13 98.24
6 INT282483 Regulation of ocd 1 0.33 2.43 0.24 95.28
7 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 91.24
8 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 91.24
9 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 91.04
10 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 91.04
11 INT90 Localization of Gast 400 0.81 137.67 113 89.92
12 INT7253 Negative_regulation of Localization of Gast 70 0.59 21.06 20.06 89.92
13 INT125711 Negative_regulation of TSS 6 0.51 3.64 0.12 87.80
14 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69 86.08
15 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 84.24
16 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 84.24
17 INT153297 Regulation of MEFV 6 0.40 11.09 0.71 84.12
18 INT149669 Positive_regulation of MEFV 12 0.46 14.17 2.07 83.48
19 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 80.68
20 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 78.24
21 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 77.44
22 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 77.44
23 INT64175 Negative_regulation of Gene_expression of CPOX 66 0.38 39.64 23.07 77.44
24 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 77.36
25 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 77.36
26 INT81695 Gene_expression of OSM 14 0.75 7.29 3.58 77.36
27 INT148085 Binding of CXCL10 14 0.32 10.22 3.81 75.60
28 INT104931 Binding of TNFSF10 15 0.36 17.44 2.07 75.60
29 INT260819 Binding of OSM 2 0.12 0.66 0.03 75.60
30 INT233 Binding of Gast 31 0.42 17.07 5.21 75.00
31 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 75.00
32 INT50050 Gene_expression of CSRP1 23 0.76 16.84 5.86 75.00
33 INT3373 Positive_regulation of Bw22 1 0.29 0.99 0.14 74.40
34 INT2064 Positive_regulation of BTG3 29 0.49 25.58 15.37 73.84
35 INT9210 Regulation of IL6 166 0.62 125.61 49.95 71.92
36 INT150395 Binding of MEFV 55 0.44 31.18 3.42 71.52
37 INT61076 Gene_expression of RHD 9 0.65 3.52 1.39 63.36
38 INT6852 Localization of TNF 883 0.81 705.95 270.84 63.00
39 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79 61.08
40 INT2103 Localization of Rhd 35 0.77 3.16 23.5 59.84
41 INT2065 Binding of BTG3 15 0.36 10.9 4.65 59.76
42 INT6481 Binding of TNF 624 0.48 510.2 214.82 59.76
43 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 58.76
44 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 56.08
45 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 55.28
46 INT151538 Positive_regulation of Fmr1 21 0.68 12.24 2.07 54.24
47 INT246552 Transcription of Fmr1 11 0.72 6.72 0.71 54.24
48 INT287577 Positive_regulation of Transcription of Fmr1 2 0.48 2.5 0.16 54.24
49 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 51.56
50 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1 51.56
51 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 50.00
52 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 48.72
53 INT3374 Positive_regulation of Positive_regulation of MRAP 1 0.49 0.7 0.07 46.64
54 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 46.60
55 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3 45.76
56 INT170755 Positive_regulation of Positive_regulation of IFN1@ 17 0.67 8.72 3.65 45.56
57 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 45.48
58 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 45.16
59 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97 43.76
60 INT129358 Gene_expression of ELOVL1 23 0.66 29.39 2.83 34.60
61 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 34.56
62 INT31 Negative_regulation of Gene_expression of Gast 10 0.42 5.3 3.34 33.68
63 INT180163 Positive_regulation of Nfasc 49 0.40 31.96 9.41 28.56
64 INT180160 Positive_regulation of Binding of Gast 2 0.32 2.72 0.12 28.56
65 INT19775 Localization of Il1 183 0.78 145.5 50.91 22.60
66 INT169173 Gene_expression of ocd 9 0.50 4.49 1.28 16.00
67 INT11048 Gene_expression of CD69 59 0.67 42.85 6.4 15.36
68 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 13.60
69 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 13.12
70 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 13.12
71 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 13.12
72 INT20944 Gene_expression of Mcf2l 13 0.58 5.96 4.76 12.08
73 INT173170 Gene_expression of PPA1 5 0.06 3.11 0.47 8.16
74 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95 7.68
75 INT65515 Binding of ocd 7 0.36 6.62 1.48 7.52
76 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
77 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
78 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
79 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
80 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 5.00
81 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
82 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
83 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 5.00
84 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 5.00
85 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
86 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
87 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
88 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
89 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
90 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
91 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
92 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
93 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
94 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 5.00
95 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 5.00
96 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
97 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
98 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
99 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
100 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 5.00
101 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
102 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
103 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 5.00
104 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
105 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
106 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
107 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
108 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
109 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 5.00
110 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
111 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 5.00
112 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47 5.00
113 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
114 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 5.00
115 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
116 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 5.00
117 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
118 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
119 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
120 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 5.00
121 INT65698 Localization of CCL2 118 0.81 77.54 32.69 5.00
122 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 5.00
123 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 5.00
124 INT91 Positive_regulation of Localization of Gast 96 0.70 23.22 29.36 5.00
125 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 5.00
126 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 5.00
127 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
128 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
129 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13 5.00
130 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
131 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
132 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
133 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
134 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22 5.00
135 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 5.00
136 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08 5.00
137 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02 5.00
138 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
139 INT636 Binding of MRAP 54 0.48 40.36 18.77 5.00
140 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 5.00
141 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
142 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67 5.00
143 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 5.00
144 INT59365 Gene_expression of HTR1A 41 0.75 16.31 16.57 5.00
145 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 5.00
146 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 5.00
147 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
148 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
149 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 5.00
150 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 5.00
151 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
152 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75 5.00
153 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21 5.00
154 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
155 INT28314 Negative_regulation of Gene_expression of Gabrg1 29 0.44 12.56 13.8 5.00
156 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 5.00
157 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
158 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
159 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 5.00
160 INT132178 Binding of CD80 41 0.47 15.55 12.98 5.00
161 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 5.00
162 INT120828 Localization of CXCL10 29 0.68 18.01 12.17 5.00
163 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 5.00
164 INT148639 Gene_expression of Uchl1 30 0.59 16.76 11.54 5.00
165 INT55886 Negative_regulation of Gene_expression of Il4 47 0.57 26.04 11.42 5.00
166 INT80756 Gene_expression of CD86 77 0.77 46.68 11.36 5.00
167 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
168 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 5.00
169 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38 5.00
170 INT58449 Binding of Mthfd1 47 0.47 22.02 10.29 5.00
171 INT145875 Gene_expression of Grm2 28 0.58 6.81 10.19 5.00
172 INT73504 Binding of CD28 35 0.45 15.99 10.04 5.00
173 INT6065 Localization of GRIN1 15 0.74 3.15 9.81 5.00
174 INT80549 Binding of ICAM1 53 0.47 42.76 9.72 5.00
175 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
176 INT144689 Regulation of RCT 49 0.53 25.91 9.6 5.00
177 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 5.00
178 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32 5.00
179 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24 5.00
180 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
181 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
182 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 5.00
183 INT186273 Negative_regulation of Il13 33 0.46 22.88 8.65 5.00
184 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
185 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 5.00
186 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27 5.00
187 INT69460 Positive_regulation of Grm2 12 0.49 6.54 8.18 5.00
188 INT132278 Binding of CTLA4 32 0.39 18.69 8.17 5.00
189 INT112104 Binding of Grin2b 21 0.44 6.78 8.16 5.00
190 INT117543 Regulation of Gene_expression of CD14 21 0.59 6.66 7.67 5.00
191 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48 5.00
192 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 5.00
193 INT101121 Regulation of Comt 19 0.53 10.66 7.22 5.00
194 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 5.00
195 INT28315 Regulation of Gene_expression of Gabrg1 20 0.60 4.78 7 5.00
196 INT117544 Regulation of CD14 24 0.45 5.85 6.66 5.00
197 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 5.00
198 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
199 INT61417 Gene_expression of ITGAL 36 0.75 29.62 6.15 5.00
200 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12 5.00
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