D:Stress

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pChart

Disease Term
Synonyms Stresses
Documents 25013
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Stress. They are ordered first by their relevance to Stress and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT306641 Mapk1 Regulation of Mstn 1 0.21 3.2 0 100.00
2 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54 100.00
3 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5 100.00
4 INT244452 CS Positive_regulation of Phosphorylation of EIF2S2 1 0.21 2.07 0.09 100.00
5 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61 100.00
6 INT306621 Mstn Regulation of Positive_regulation of Myef2 1 0.19 1.39 0 100.00
7 INT306639 Mapk1 Regulation of Positive_regulation of Myef2 1 0.08 1.33 0 100.00
8 INT306622 Mapk1 Positive_regulation of Positive_regulation of Myef2 1 0.06 1.3 0 100.00
9 INT306628 Mapk1 Positive_regulation of Gene_expression of Mstn 1 0.17 1.3 0 100.00
10 INT306630 Mapk1 Regulation of Gene_expression of Mstn 1 0.09 1.21 0 100.00
11 INT162288 Regulation of Binding of TUBA1A and Phospho2 1 0.24 1.28 0.4 100.00
12 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27 100.00
13 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44 100.00
14 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28 100.00
15 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59 100.00
16 INT137308 sps Negative_regulation of Cstb 1 0.03 1.59 0.31 100.00
17 INT252818 PPP2R4 Regulation of Positive_regulation of DDIT3 1 0.04 3.07 0.04 100.00
18 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06 100.00
19 INT223558 Dpcr1 Regulation of Cms1 1 0.00 0.79 0.51 100.00
20 INT229825 Fos Positive_regulation of Mt2A 1 0.41 0.71 0 100.00
21 INT241256 TP53 Regulation of OPCML 1 0.12 1.31 0 100.00
22 INT306637 Prep Positive_regulation of Positive_regulation of Mstn 1 0.12 0.62 0 100.00
23 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19 100.00
24 INT256707 Eif2ak3 Regulation of Gene_expression of Wfs1 1 0.10 0.78 0.03 100.00
25 INT157146 LSS Negative_regulation of Positive_regulation of TNF 1 0.25 1.08 0.21 100.00
26 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17 100.00
27 INT242974 Mapk8 Negative_regulation of Positive_regulation of Esr1 1 0.01 1.39 0.05 100.00
28 INT182494 TNF Positive_regulation of OLR1 1 0.05 2.51 0.13 100.00
29 INT182493 HGS Positive_regulation of OLR1 1 0.00 2.51 0.13 100.00
30 INT341879 Oxt Negative_regulation of Positive_regulation of Hpse 1 0.01 0.83 0.11 100.00
31 INT157150 Positive_regulation of PTGIR Negative_regulation of Gene_expression of TNF 1 0.12 0.97 0.34 100.00
32 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96 100.00
33 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35 100.00
34 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35 100.00
35 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35 100.00
36 INT157147 LSS Positive_regulation of PTGIR 1 0.09 0.96 0.36 100.00
37 INT256702 Binding of Wfs1 and Tmed4 1 0.01 0.61 0 100.00
38 INT244457 CS Positive_regulation of Gene_expression of ESR1 1 0.07 0.67 0 100.00
39 INT157151 LSS Positive_regulation of CPOX 1 0.17 0.89 0.05 100.00
40 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 100.00
41 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1 100.00
42 INT186244 Binding of AGRP and ALB 1 0.03 0.53 0.1 100.00
43 INT157148 LSS Negative_regulation of TNF 1 0.25 0.74 0.35 100.00
44 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3 100.00
45 INT223828 Binding of GSTP1 and MAPK8 1 0.06 1.8 0.21 100.00
46 INT115597 Avp Positive_regulation of Crh 1 0.56 0.79 0.31 100.00
47 INT306633 Myoz1 Regulation of Gene_expression of Mstn 1 0.01 0.39 0 100.00
48 INT306618 Myoz1 Regulation of Pik3r1 1 0.00 0.39 0 100.00
49 INT306649 Myoz1 Regulation of Ahsa1 1 0.00 0.39 0 100.00
50 INT306646 Mapk1 Regulation of Pik3r1 1 0.03 0.39 0 100.00
51 INT306650 Mapk1 Regulation of Ahsa1 1 0.02 0.39 0 100.00
52 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29 100.00
53 INT172838 Binding of ISL1 and T2dm2 1 0.00 2.41 0 100.00
54 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35 100.00
55 INT229810 Fos Positive_regulation of Sod3 1 0.40 0.38 0 100.00
56 INT229826 Fos Positive_regulation of Sod1 1 0.42 0.38 0 100.00
57 INT229818 Fos Positive_regulation of Hmox1 1 0.43 0.37 0 100.00
58 INT31844 Grpr Regulation of Localization of Prl 1 0.04 0.37 0.47 100.00
59 INT229863 Fos Positive_regulation of GSTK1 1 0.03 0.37 0 100.00
60 INT229827 Fos Positive_regulation of Mt1a 1 0.40 0.36 0 100.00
61 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68 100.00
62 INT186540 Binding of Cort and Hpse 1 0.05 0.92 0.08 100.00
63 INT31843 Grpr Negative_regulation of Localization of Prl 1 0.03 0.34 0.34 100.00
64 INT120381 Binding of CNR1 and Fos 1 0.00 0.52 0.68 100.00
65 INT194675 MAPK14 Positive_regulation of CREB1 1 0.07 0.33 0 100.00
66 INT194684 MAPK14 Positive_regulation of Transcription of CREB1 1 0.07 0.33 0 100.00
67 INT160159 Gene_expression of CYP2C9 Positive_regulation of HSP90B2P 1 0.13 0.53 0.09 100.00
68 INT317319 Binding of Trap1 and Pink1 1 0.26 2.67 0 100.00
69 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26 100.00
70 INT327404 Binding of Xiap and Siva1 1 0.02 1.97 0.03 100.00
71 INT307156 Esr1 Positive_regulation of Hspa5 1 0.04 0.79 0 100.00
72 INT244450 TMBIM6 Negative_regulation of Gene_expression of ESR1 1 0.04 0.68 0 100.00
73 INT244451 TMBIM6 Negative_regulation of Gene_expression of XBP1 1 0.13 0.68 0 100.00
74 INT30419 Gnrhr Regulation of Sst 1 0.02 0.27 0.15 100.00
75 INT30421 Gnrhr Regulation of Crh 1 0.11 0.27 0.15 100.00
76 INT306629 Mapk1 Positive_regulation of Positive_regulation of Mstn 1 0.16 0.26 0 100.00
77 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 100.00
78 INT319313 Socs4 Positive_regulation of Mapk14 1 0.02 0.68 0.41 100.00
79 INT319312 Socs4 Positive_regulation of Mapk8 1 0.05 0.68 0.41 100.00
80 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05 100.00
81 INT9291 Regulation of Pomc Regulation of Prl 1 0.05 0.69 0.49 100.00
82 INT244459 ERN1 Regulation of Positive_regulation of MAPK8 1 0.03 0.47 0 100.00
83 INT9290 Pomc Regulation of Prl 2 0.09 0.69 0.71 100.00
84 INT148580 TNF Regulation of Gene_expression of SAMD9 1 0.48 3.01 0.5 100.00
85 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1 100.00
86 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1 100.00
87 INT201540 GADD45G Negative_regulation of NPC1 1 0.32 1.7 0 100.00
88 INT311531 IMMT Negative_regulation of Gene_expression of ROS1 1 0.11 1.09 0.24 100.00
89 INT289789 Comp Positive_regulation of Gene_expression of Rer1 1 0.55 0.8 0.03 100.00
90 INT215875 Atf4 Regulation of Mapkap1 1 0.29 0.43 0.04 100.00
91 INT215882 Atf4 Regulation of Xbp1 1 0.28 0.43 0.04 100.00
92 INT215871 Atf4 Regulation of Ddit3 1 0.26 0.43 0.04 100.00
93 INT215876 Atf4 Regulation of Hspa5 1 0.22 0.43 0.04 100.00
94 INT6975 Zeb1 Positive_regulation of St8sia1 1 0.03 0.17 0.91 100.00
95 INT256079 Serpina3k Negative_regulation of Fig4 1 0.07 0.16 0 100.00
96 INT256082 Serpina3k Negative_regulation of Positive_regulation of Fig4 1 0.07 0.16 0 100.00
97 INT172829 Binding of Nfkb1 and ISYNA1 1 0.00 2.06 0.17 100.00
98 INT172820 Binding of Nfkb1 and T2dm2 1 0.00 2.14 0.17 100.00
99 INT306638 Prep Positive_regulation of Positive_regulation of Nfatc4 1 0.09 0.16 0 100.00
100 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36 100.00
101 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21 100.00
102 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2 100.00
103 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 100.00
104 INT95403 Ephb1 Regulation of Positive_regulation of Trib3 1 0.07 0.19 0.41 100.00
105 INT343916 Hspa1a Positive_regulation of Gene_expression of TNF 1 0.16 1.17 0.41 100.00
106 INT95402 Mapk14 Regulation of Positive_regulation of Trib3 1 0.06 0.19 0.41 100.00
107 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4 100.00
108 INT343907 Hspa1a Positive_regulation of Gene_expression of Cxcl2 1 0.01 1.17 0.4 100.00
109 INT346228 MAP2K6 Positive_regulation of Positive_regulation of MAPK14 1 0.44 0.68 0.34 100.00
110 INT344748 NFKB2 Regulation of Gene_expression of GAD1 1 0.07 0.87 0.33 100.00
111 INT259639 MAPK14 Regulation of Gene_expression of IL8 1 0.02 1.2 0.32 100.00
112 INT312573 AMBP Negative_regulation of IL6 1 0.11 1.41 0.32 100.00
113 INT312571 AMBP Negative_regulation of Positive_regulation of IL6 1 0.11 1.41 0.32 100.00
114 INT354821 Nos2 Positive_regulation of Eif2ak2 1 0.06 0.64 0.3 100.00
115 INT286702 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.29 100.00
116 INT286705 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29 100.00
117 INT286703 Mapk1 Positive_regulation of Phosphorylation of Hist1h3f 1 0.22 0.18 0.29 100.00
118 INT286706 Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29 100.00
119 INT286709 Mapk1 Positive_regulation of Rps6ka5 Positive_regulation of Rps6ka5 1 0.36 0.18 0.28 100.00
120 INT286701 Rps6ka5 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.18 0.28 100.00
121 INT286707 Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.28 100.00
122 INT175320 Tlr4 Positive_regulation of Gene_expression of Mmp9 1 0.01 0.54 0.21 100.00
123 INT179937 Trib3 Regulation of TNF 1 0.00 0.59 0.2 100.00
124 INT327557 Pla2g4a Positive_regulation of Phosphorylation of Ptgs2 1 0.14 1.03 0.1 100.00
125 INT215874 Positive_regulation of Eif2ak3 Positive_regulation of Positive_regulation of Ddit3 1 0.47 0.31 0.07 100.00
126 INT319973 App Regulation of Gene_expression of Mapk12 1 0.02 0.98 0.04 100.00
127 INT181086 Binding of Akt1 and Cdc42ep3 1 0.00 0.79 0.03 100.00
128 INT316773 Esr1 Positive_regulation of Ddit3 1 0.02 0.41 0.03 100.00
129 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03 100.00
130 INT181079 Binding of Akt1 and Errfi1 1 0.00 0.8 0.03 100.00
131 INT292679 GOPC Positive_regulation of HSP90AA1 1 0.01 0.1 0 100.00
132 INT258209 ROCK1 Regulation of ARR3 1 0.00 0.2 0 100.00
133 INT258202 ROCK1 Positive_regulation of MYL2 1 0.14 0.2 0 100.00
134 INT272867 Binding of NLRP1 and COPD 1 0.00 1.07 0 100.00
135 INT227486 pk Positive_regulation of Gene_expression of Ptgs1 1 0.03 0.17 0 100.00
136 INT318219 SIRT1 Regulation of TBK1 1 0.03 0.43 0 100.00
137 INT247640 Atf3 Positive_regulation of Gtf3a 1 0.01 0.99 0 100.00
138 INT247638 Atf3 Positive_regulation of Hspb2 1 0.01 1 0 100.00
139 INT292725 GOPC Positive_regulation of Protein_catabolism of Akt1 1 0.01 0.1 0 100.00
140 INT318217 SIRT1 Regulation of TP53 1 0.07 0.43 0 100.00
141 INT307212 Ide Regulation of Lep 1 0.00 0.51 0 100.00
142 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93 99.98
143 INT352895 Positive_regulation of Binding of ROS1 and GOPC 1 0.08 0.68 0.26 99.98
144 INT319680 Keap1 Negative_regulation of Positive_regulation of Nfe2l2 1 0.36 0.93 0.17 99.96
145 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08 99.96
146 INT192863 Binding of Ddit3 and Esr1 1 0.09 0.67 0.08 99.96
147 INT192860 Binding of Calr and Esr1 1 0.06 0.67 0.08 99.96
148 INT192865 Binding of Esr1 and Pdia3 1 0.07 0.67 0.08 99.96
149 INT131598 Keap1 Negative_regulation of Nfe2l2 2 0.65 1.27 0.08 99.96
150 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26 99.96
151 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1 99.96
152 INT311535 ROS1 Negative_regulation of CA2 1 0.19 0.61 0.04 99.96
153 INT244471 TMBIM6 Negative_regulation of ESR1 1 0.04 0.68 0 99.96
154 INT215872 Atf4 Regulation of Esr1 1 0.30 0.42 0.03 99.96
155 INT141019 Crh Positive_regulation of Gene_expression of Pomc 1 0.20 0.1 0.31 99.96
156 INT162289 Binding of TUBA1A and Phospho2 1 0.31 1.26 0.4 99.92
157 INT235088 NOS1 Regulation of ISYNA1 1 0.07 0.75 0.23 99.92
158 INT239804 HSF1 Positive_regulation of HSR 1 0.16 2.09 0.05 99.92
159 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58 99.92
160 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14 99.92
161 INT141315 Gs Regulation of Kcnk10 1 0.16 0.64 0.27 99.92
162 INT339695 Binding of CYP3A4 and TRO 1 0.06 0.57 0.05 99.92
163 INT306634 Positive_regulation of Myef2 Regulation of Mstn 1 0.12 1.33 0 99.90
164 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19 99.90
165 INT175909 Binding of ROS1 and CNBP 1 0.01 1.78 0.19 99.90
166 INT306625 Mstn Regulation of Mrpl47 1 0.01 0.7 0 99.88
167 INT319308 Socs4 Positive_regulation of Prkca 1 0.05 0.67 0.41 99.88
168 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 99.84
169 INT352891 Binding of ROS1 and GOPC 1 0.09 1.34 0.53 99.82
170 INT158878 CRX Positive_regulation of Gene_expression of Fos 1 0.02 1.49 0.41 99.80
171 INT305271 Binding of Lep and Obsty1 1 0.06 4.86 0 99.80
172 INT252801 PPP2R4 Regulation of Positive_regulation of CREB1 1 0.01 2.71 0.04 99.78
173 INT252780 Positive_regulation of CREB1 Positive_regulation of PPP2R4 1 0.01 2.71 0.04 99.78
174 INT112617 Pdpk1 Regulation of Il1b 1 0.03 1.11 0.36 99.78
175 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36 99.78
176 INT255934 Tauph Positive_regulation of Map3k1 1 0.00 0.1 0.32 99.78
177 INT255946 MAPK14 Positive_regulation of Map3k1 1 0.04 0.1 0.32 99.78
178 INT25490 Binding of ENG and TFPI 1 0.27 0.4 0.06 99.76
179 INT290858 Positive_regulation of Ca2 Regulation of PPR 1 0.01 0.5 0.18 99.74
180 INT105772 SST Negative_regulation of Localization of GH1 1 0.10 0.54 0.38 99.74
181 INT105770 SST Negative_regulation of Localization of TRH 1 0.17 0.54 0.38 99.74
182 INT273945 Crh Positive_regulation of Gene_expression of Crem 1 0.20 0.52 0.43 99.74
183 INT349131 Binding of Ltp and Cfp 1 0.04 1.08 0.3 99.72
184 INT341896 Oxt Regulation of Localization of POMC 1 0.07 0.91 0.19 99.72
185 INT256706 Binding of Hsp90b1 and Wfs1 1 0.43 5.02 0.2 99.68
186 INT355438 Gene_expression of Pdia3 Negative_regulation of Gene_expression of Ddit3 1 0.05 4.79 0.06 99.68
187 INT105771 CRH Negative_regulation of Localization of GNRH1 1 0.35 0.56 0.39 99.68
188 INT273953 Crem Regulation of Transcription of Crh 1 0.26 0.99 0.27 99.68
189 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07 99.68
190 INT345484 Binding of MCL1 and PMAIP1 1 0.04 0.8 0 99.68
191 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 99.66
192 INT265452 Binding of TNFRSF10B and RNU5A-1 1 0.05 0.67 0 99.64
193 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21 99.64
194 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21 99.64
195 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45 99.64
196 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21 99.64
197 INT62449 Gnrh1 Regulation of Crh 1 0.40 0.34 0.91 99.62
198 INT62447 Gnrh1 Regulation of Localization of Crh 1 0.40 0.17 0.45 99.62
199 INT280806 Avpr1b Positive_regulation of Localization of Pomc 1 0.19 0.17 0 99.62
200 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07 99.60

Single Events

The table below shows the top 200 pain related interactions that have been reported for Stress. They are ordered first by their pain relevance and then by number of times they were reported in Stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT158 Localization of Prl 2431 0.81 378.96 952.2 100.00
2 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 100.00
3 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
4 INT1562 Localization of Crh 499 0.81 126.74 236.68 100.00
5 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 100.00
6 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 100.00
7 INT443 Localization of POMC 1020 0.81 284.52 443.17 100.00
8 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 100.00
9 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 100.00
10 INT1438 Localization of Pomc 360 0.81 101.26 116.47 100.00
11 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
12 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 100.00
13 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 100.00
14 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 100.00
15 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 100.00
16 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 100.00
17 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 100.00
18 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 100.00
19 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26 100.00
20 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 100.00
21 INT1898 Regulation of Crh 220 0.62 61.33 102.64 100.00
22 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 100.00
23 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
24 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 100.00
25 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 100.00
26 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24 100.00
27 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
28 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 100.00
29 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 100.00
30 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23 100.00
31 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
32 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 100.00
33 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 100.00
34 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 100.00
35 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 100.00
36 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 100.00
37 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 100.00
38 INT129105 Gene_expression of Mstn 95 0.76 29.96 0.32 100.00
39 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 100.00
40 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 100.00
41 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 100.00
42 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 100.00
43 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
44 INT1308 Localization of Pomc 457 0.81 66.83 217.5 100.00
45 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
46 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 100.00
47 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
48 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 100.00
49 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31 100.00
50 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25 100.00
51 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 100.00
52 INT12315 Gene_expression of Nr3c2 37 0.75 19.28 11.97 100.00
53 INT94784 Binding of ROS1 113 0.40 71.57 10.26 100.00
54 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 100.00
55 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 100.00
56 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01 100.00
57 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
58 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
59 INT112334 Regulation of NF1 18 0.52 15.85 0.34 100.00
60 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11 100.00
61 INT12319 Positive_regulation of Cort 52 0.61 22.55 29.35 100.00
62 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 100.00
63 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37 100.00
64 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 100.00
65 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 100.00
66 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 100.00
67 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
68 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 100.00
69 INT10208 Negative_regulation of Binding of Htr1a 18 0.57 13.98 8.91 100.00
70 INT462 Regulation of Pomc 157 0.62 41.67 67.27 100.00
71 INT218285 Positive_regulation of Gene_expression of Mstn 51 0.68 15.72 0.08 100.00
72 INT107291 Positive_regulation of Ghrl 58 0.67 44.6 9.68 100.00
73 INT66868 Positive_regulation of Ceacam3 40 0.69 26.61 28.9 100.00
74 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 100.00
75 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23 100.00
76 INT118565 Gene_expression of Ddit3 35 0.75 23.62 4.32 100.00
77 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 100.00
78 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 100.00
79 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15 100.00
80 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
81 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
82 INT169558 Positive_regulation of NF1 13 0.59 13.58 0 100.00
83 INT1044 Negative_regulation of Localization of LH 358 0.59 25.95 151.31 100.00
84 INT16879 Binding of Crh 72 0.48 21.65 28.43 100.00
85 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88 100.00
86 INT876 Localization of Gh1 843 0.80 67.75 340.82 100.00
87 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 100.00
88 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 100.00
89 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11 100.00
90 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01 100.00
91 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 100.00
92 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 100.00
93 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55 100.00
94 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 100.00
95 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 100.00
96 INT416 Regulation of LH 253 0.62 31.48 125.55 100.00
97 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 100.00
98 INT118390 Positive_regulation of Nfe2l2 82 0.70 20.41 10.61 100.00
99 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 100.00
100 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48 100.00
101 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 100.00
102 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 100.00
103 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 100.00
104 INT116150 Positive_regulation of Ddit3 26 0.67 22.58 5.01 100.00
105 INT244490 Gene_expression of HSP90B1 4 0.33 41.16 10.37 100.00
106 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28 100.00
107 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 100.00
108 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 100.00
109 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52 100.00
110 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 100.00
111 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 100.00
112 INT5452 Regulation of CRH 56 0.62 15.32 12.42 100.00
113 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 100.00
114 INT118559 Positive_regulation of Hspa5 20 0.61 15.66 1.45 100.00
115 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 100.00
116 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 100.00
117 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52 100.00
118 INT75585 Negative_regulation of Negative_regulation of Ltp 18 0.37 9.81 16.63 100.00
119 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11 100.00
120 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83 100.00
121 INT4207 Regulation of Avp 267 0.62 63.72 115.33 100.00
122 INT10799 Localization of ENG 63 0.78 18.67 27.28 100.00
123 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
124 INT84769 Positive_regulation of St8sia1 10 0.41 7.56 9.86 100.00
125 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 100.00
126 INT15246 Regulation of FOS 32 0.60 15.34 12.94 100.00
127 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 100.00
128 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 100.00
129 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 100.00
130 INT10879 Positive_regulation of Avp 39 0.65 14.01 8.76 100.00
131 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5 100.00
132 INT102351 Regulation of Pecam1 7 0.61 22.45 7.58 100.00
133 INT1114 Localization of Ins1 748 0.80 192.95 165.48 100.00
134 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21 100.00
135 INT27882 Gene_expression of HSP90B2P 52 0.75 36.51 9.59 100.00
136 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14 100.00
137 INT102023 Regulation of Creb1 51 0.62 16.29 16.71 100.00
138 INT128159 Positive_regulation of DDIT3 29 0.67 29.5 8.99 100.00
139 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 100.00
140 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 100.00
141 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 100.00
142 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53 100.00
143 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7 100.00
144 INT7573 Positive_regulation of Nr3c2 38 0.67 20 21.84 100.00
145 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07 100.00
146 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 100.00
147 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 100.00
148 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 100.00
149 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 100.00
150 INT128142 Regulation of Gene_expression of Gpm6a 2 0.26 5.12 1.03 100.00
151 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72 100.00
152 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 100.00
153 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17 100.00
154 INT177938 Negative_regulation of NF1 9 0.43 10.3 0.2 100.00
155 INT451 Regulation of Oxt 142 0.62 22.07 69.42 100.00
156 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7 100.00
157 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97 100.00
158 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 100.00
159 INT214 Localization of AVP 370 0.81 208.51 91.09 100.00
160 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 100.00
161 INT82762 Positive_regulation of Positive_regulation of Mapk3 23 0.67 7.72 7.91 100.00
162 INT11628 Regulation of Localization of Pomc 44 0.61 10.46 18.66 100.00
163 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 100.00
164 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 100.00
165 INT3118 Negative_regulation of Positive_regulation of POMC 33 0.59 9.42 18.07 100.00
166 INT97894 Positive_regulation of Gene_expression of Crh 27 0.70 11.82 4.82 100.00
167 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 100.00
168 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73 100.00
169 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18 100.00
170 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 100.00
171 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 100.00
172 INT251 Regulation of INS 398 0.62 232.47 55.04 100.00
173 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36 100.00
174 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 100.00
175 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 100.00
176 INT103474 Regulation of Gene_expression of BDNF 40 0.60 12.14 9.65 100.00
177 INT98310 Regulation of gr 21 0.39 15.04 6.68 100.00
178 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15 100.00
179 INT9210 Regulation of IL6 166 0.62 125.61 49.95 100.00
180 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15 100.00
181 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 100.00
182 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 100.00
183 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29 100.00
184 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73 100.00
185 INT253 Regulation of PRL 184 0.62 47.27 65.79 100.00
186 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 100.00
187 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 100.00
188 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 100.00
189 INT104600 Regulation of Gene_expression of gr 6 0.43 7.03 1.33 100.00
190 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 100.00
191 INT1436 Negative_regulation of Localization of Pomc 41 0.58 10.85 11.26 100.00
192 INT7692 Positive_regulation of PENK 71 0.70 20.34 32.54 100.00
193 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 100.00
194 INT184696 Positive_regulation of Xbp1 12 0.60 13.6 1.06 100.00
195 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 100.00
196 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 100.00
197 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 100.00
198 INT610 Regulation of PENK 47 0.62 14.17 31.55 100.00
199 INT129 Localization of OXTR 51 0.80 11.08 15.36 100.00
200 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 100.00
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