D:Stuttering

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Disease Term
Synonyms ACQUIRED STUTTERING, Adult Stuttering, Childhood Stuttering, Developmental Stuttering, Stammering, STUTTERING ACQUIRED, STUTTERING ADULT, Stuttering Childhood, Stuttering Developmental
Documents 77
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Stuttering. They are ordered first by their relevance to Stuttering and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 66.24
2 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34 66.24
3 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11 66.24
4 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
5 INT264209 Binding of Igh-Lev and Sv2a 1 0.17 1.78 0.38 5.00
6 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31 5.00
7 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31 5.00
8 INT258766 Binding of Csf2 and ADHD1 1 0.01 0.69 0.27 5.00
9 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25 5.00
10 INT310497 Neurog2 Positive_regulation of Fate1 1 0.07 0.36 0.21 5.00
11 INT302712 Binding of Hprt and Hrh1 1 0.25 1.07 0.2 5.00
12 INT302711 Binding of Hrh1 and Spnb4 1 0.18 1.07 0.2 5.00
13 INT310498 Gene_expression of Neurog2 Positive_regulation of Positive_regulation of Eomes 1 0.20 0.42 0.19 5.00
14 INT310494 Gene_expression of Dlx2 Positive_regulation of Fate1 1 0.04 0.1 0.18 5.00
15 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12 5.00
16 INT258765 Lmo1 Regulation of ADHD1 1 0.05 1.98 0.09 5.00
17 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08 5.00
18 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08 5.00
19 INT258768 Drd2 Regulation of ADHD1 1 0.14 0.79 0.07 5.00
20 INT310496 Binding of Neurog2 and Mtap2 1 0.17 0.44 0.05 5.00
21 INT264210 Binding of Aes and Igh-Lev 1 0.07 0.41 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Stuttering. They are ordered first by their pain relevance and then by number of times they were reported in Stuttering. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT56658 Gene_expression of Spnb4 7 0.58 5.6 2.22 98.08
2 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28 91.76
3 INT98686 Gene_expression of Calb2 28 0.51 12.07 2.84 91.12
4 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 84.56
5 INT54296 Regulation of Spnb4 3 0.44 2.06 0.89 76.24
6 INT131472 Regulation of Pde5a 11 0.42 6.95 3.06 75.68
7 INT257299 Binding of Pde5a 14 0.27 4.31 2.45 74.72
8 INT264206 Gene_expression of Igh-Lev 1 0.30 5.68 0.87 73.52
9 INT185252 Gene_expression of Dlx2 7 0.71 8.8 6.24 69.64
10 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54 69.64
11 INT184652 Binding of RRM1 5 0.22 0.55 0.23 68.24
12 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25 67.68
13 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 67.28
14 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 66.28
15 INT310467 Positive_regulation of Localization of Fate1 1 0.04 0.3 0.05 65.76
16 INT310487 Localization of Fate1 1 0.06 0.3 0.05 65.76
17 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 95 0.43 24.83 15.69 64.00
18 INT182454 Binding of Tg(CAG-EGFP)D4Nagy 28 0.29 3.29 1.11 62.64
19 INT229153 Gene_expression of Esyt2 12 0.21 2.14 3.76 57.92
20 INT22825 Regulation of Gtf3a 36 0.25 19.93 5.03 55.48
21 INT310471 Regulation of Ascl1 1 0.34 0.19 0.22 55.48
22 INT302340 Positive_regulation of Gene_expression of Dlx2 2 0.64 3.43 2.15 54.68
23 INT274773 Gene_expression of RRM2 1 0.08 0.21 0.15 49.76
24 INT132385 Gene_expression of Neurog2 12 0.73 7.03 3.44 48.00
25 INT310477 Positive_regulation of Dlx2 1 0.46 0.47 0.23 42.64
26 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 41.68
27 INT310469 Negative_regulation of Gene_expression of Dlx2 1 0.39 0.66 0.16 40.00
28 INT157720 Localization of ADHD1 15 0.64 15.84 1.69 37.76
29 INT302707 Phosphorylation of Spnb4 1 0.28 3.13 0 31.40
30 INT114201 Gene_expression of Slc32a1 8 0.78 14.2 7.21 17.92
31 INT229145 Regulation of Gene_expression of Mnda 1 0.03 0 0 13.20
32 INT29393 Positive_regulation of APRT 18 0.67 5.28 2.13 11.88
33 INT229146 Gene_expression of Mnda 4 0.05 0.09 0.28 11.44
34 INT310465 Binding of Dlx2 1 0.34 0.33 0.11 10.40
35 INT80498 Gene_expression of DSP 15 0.75 7.06 0.79 9.76
36 INT75629 Gene_expression of Mtap2 41 0.66 8.19 4.51 7.44
37 INT294805 Gene_expression of Dlx1 4 0.70 0.45 0.81 5.12
38 INT294809 Positive_regulation of Gene_expression of Dlx1 2 0.37 0.21 0.16 5.12
39 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
40 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
41 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
42 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 5.00
43 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 5.00
44 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
45 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 5.00
46 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78 5.00
47 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 5.00
48 INT55671 Gene_expression of Ik 151 0.27 80.1 48.49 5.00
49 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 5.00
50 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 5.00
51 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72 5.00
52 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
53 INT13501 Binding of Drd2 65 0.48 23.76 35.6 5.00
54 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28 5.00
55 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
56 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
57 INT2650 Positive_regulation of Slc3a1 50 0.57 2.95 27.52 5.00
58 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 5.00
59 INT12392 Regulation of Slc3a1 45 0.36 7.57 25.66 5.00
60 INT12484 Binding of Drd2 45 0.48 15.17 24.72 5.00
61 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 5.00
62 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27 5.00
63 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
64 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 5.00
65 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85 5.00
66 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 5.00
67 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65 5.00
68 INT7952 Localization of Slc3a1 32 0.81 1.28 15.69 5.00
69 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24 5.00
70 INT69878 Positive_regulation of Gene_expression of Gtf3a 48 0.29 36.78 13.57 5.00
71 INT94861 Gene_expression of Pde5a 40 0.69 14.73 13.27 5.00
72 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32 5.00
73 INT158070 Localization of Aes 23 0.65 19.93 10.9 5.00
74 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8 5.00
75 INT121796 Gene_expression of NeuN 92 0.78 23.18 10.53 5.00
76 INT27937 Gene_expression of Klkb1 35 0.55 1.86 10.08 5.00
77 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42 5.00
78 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 5.00
79 INT13296 Transcription of Drd2 17 0.66 2.7 9.07 5.00
80 INT61399 Positive_regulation of Ik 21 0.22 10.17 8.75 5.00
81 INT184864 Gene_expression of Lmo1 16 0.26 8.09 8.48 5.00
82 INT12861 Gene_expression of Cish 40 0.57 23.01 8.48 5.00
83 INT170504 Positive_regulation of Gene_expression of Car2 60 0.41 19.1 8.45 5.00
84 INT139930 Gene_expression of Slc17a7 35 0.75 6.22 8.33 5.00
85 INT156396 Localization of Tg(CAG-EGFP)D4Nagy 61 0.55 13.63 8.17 5.00
86 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12 5.00
87 INT101189 Transcription of Gtf3a 49 0.17 24.39 7.93 5.00
88 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76 5.00
89 INT18190 Regulation of DRD2 11 0.60 9.01 7.63 5.00
90 INT79502 Gene_expression of Pvalb 26 0.78 2.83 7.46 5.00
91 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 5.00
92 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
93 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55 5.00
94 INT79822 Gene_expression of Htr1b 10 0.65 2.92 6.27 5.00
95 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 5.00
96 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 5.00
97 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93 5.00
98 INT80033 Binding of FAS 37 0.48 41.19 5.67 5.00
99 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29 5.00
100 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23 5.00
101 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 5.00
102 INT1375 Negative_regulation of Pde4dl1 13 0.57 5.54 4.63 5.00
103 INT15001 Localization of Gfap 29 0.75 6.71 4.1 5.00
104 INT199692 Gene_expression of Mkrn1 48 0.75 15.2 3.84 5.00
105 INT229148 Gene_expression of Mtap6 3 0.67 1.92 3.58 5.00
106 INT168003 Localization of Fgf2 24 0.80 12.52 3.31 5.00
107 INT88289 Gene_expression of Hmmr 11 0.08 1.84 3.24 5.00
108 INT25906 Negative_regulation of Cish 6 0.29 5.41 3.17 5.00
109 INT181804 Negative_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 57 0.50 12.54 3 5.00
110 INT83404 Positive_regulation of Gucy1b2 9 0.68 5.18 2.74 5.00
111 INT14447 Localization of F2 20 0.79 12.77 2.67 5.00
112 INT129695 Binding of Sv2a 6 0.47 4.96 2.51 5.00
113 INT49454 Negative_regulation of Gene_expression of Gtf3a 13 0.08 9.99 2.43 5.00
114 INT229151 Negative_regulation of Mtap6 2 0.43 0.98 2.41 5.00
115 INT127293 Positive_regulation of NeuN 9 0.33 2.44 2.36 5.00
116 INT206514 Transcription of Tg(CAG-EGFP)D4Nagy 19 0.59 3.25 2.32 5.00
117 INT257301 Protein_catabolism of Pde5a 5 0.30 1.97 2.26 5.00
118 INT19804 Negative_regulation of Hprt 18 0.59 20.6 2.17 5.00
119 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 5.00
120 INT61686 Positive_regulation of Gene_expression of Slc3a1 5 0.24 1.74 2.13 5.00
121 INT184857 Positive_regulation of Lmo1 4 0.23 4.59 2.03 5.00
122 INT3496 Negative_regulation of HPRT1 7 0.58 25.05 1.92 5.00
123 INT56656 Positive_regulation of Spnb4 3 0.49 1.09 1.92 5.00
124 INT114746 Gene_expression of Sepp1 15 0.60 3.33 1.86 5.00
125 INT67710 Binding of Sepp1 3 0.41 1.77 1.83 5.00
126 INT172961 Localization of Egf 26 0.71 16.74 1.81 5.00
127 INT115850 Localization of Mtap2 10 0.73 3.68 1.76 5.00
128 INT59790 Binding of BCR 16 0.36 15.34 1.75 5.00
129 INT55704 Positive_regulation of Gucy1a2 6 0.50 1.24 1.7 5.00
130 INT184852 Positive_regulation of Gene_expression of ADHD1 6 0.40 5.06 1.66 5.00
131 INT310489 Gene_expression of Fate1 1 0.07 1.49 1.63 5.00
132 INT30039 Negative_regulation of HAL 7 0.42 4.32 1.61 5.00
133 INT108913 Positive_regulation of HAL 10 0.28 5.71 1.59 5.00
134 INT88726 Gene_expression of HPRT1 36 0.78 10.12 1.58 5.00
135 INT229150 Localization of Mtap6 2 0.65 0.42 1.54 5.00
136 INT53008 Gene_expression of Nr4a2 25 0.74 4.89 1.5 5.00
137 INT50010 Negative_regulation of CHR 5 0.42 3.64 1.41 5.00
138 INT294804 Positive_regulation of Gene_expression of Neurog2 3 0.57 2.69 1.26 5.00
139 INT199681 Gene_expression of SERPINA5 13 0.36 15.42 1.25 5.00
140 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 5.00
141 INT77216 Localization of DRD2 3 0.75 0 1.19 5.00
142 INT58211 Gene_expression of FURIN 7 0.57 0.62 1.15 5.00
143 INT305488 Binding of Slc17a7 2 0.32 2.61 1.13 5.00
144 INT123542 Regulation of Sepp1 9 0.59 0.94 1.1 5.00
145 INT229147 Transcription of Mtap6 2 0.46 0.48 1.1 5.00
146 INT11934 Regulation of Sv2a 4 0.44 1.72 1.1 5.00
147 INT264207 Binding of Igh-Lev 1 0.25 4.13 1.07 5.00
148 INT149380 Localization of Cish 3 0.64 3.44 1.06 5.00
149 INT19803 Gene_expression of Hprt 15 0.67 4.81 1.03 5.00
150 INT86160 Regulation of Pvalb 4 0.39 0.53 0.99 5.00
151 INT263912 Positive_regulation of SLN 6 0.39 0.66 0.99 5.00
152 INT202579 Regulation of Gene_expression of DRD2 4 0.41 1.11 0.99 5.00
153 INT30041 Binding of HAL 8 0.35 2.36 0.95 5.00
154 INT264833 Gene_expression of Emx1 3 0.70 0.11 0.88 5.00
155 INT180240 Binding of Gad1 7 0.47 2.99 0.86 5.00
156 INT258745 Binding of Lmo1 3 0.11 5.92 0.84 5.00
157 INT216107 Gene_expression of Imraq1 30 0.08 6.11 0.8 5.00
158 INT57008 Positive_regulation of HPRT1 11 0.50 2.81 0.74 5.00
159 INT117529 Negative_regulation of Pde9a 2 0.06 1.55 0.71 5.00
160 INT258746 Binding of Rends1 1 0.01 1.57 0.68 5.00
161 INT255276 Positive_regulation of Slc17a7 5 0.59 1.88 0.68 5.00
162 INT148564 Localization of HAL 8 0.68 2.46 0.62 5.00
163 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61 5.00
164 INT40343 Negative_regulation of Pde8a 2 0.46 1.11 0.6 5.00
165 INT182677 Gene_expression of Emx2 11 0.78 2.14 0.59 5.00
166 INT263678 Negative_regulation of Igh-Lev 2 0.19 0.81 0.58 5.00
167 INT255313 Positive_regulation of Positive_regulation of AIS 2 0.04 3.83 0.55 5.00
168 INT231296 Gene_expression of Syn1 8 0.23 0.65 0.49 5.00
169 INT156338 Binding of gp 9 0.39 0.15 0.41 5.00
170 INT151940 Positive_regulation of Igh-Lev 2 0.41 4.51 0.41 5.00
171 INT62094 Binding of GNAQ 2 0.36 0.71 0.38 5.00
172 INT264203 Localization of Igh-Lev 1 0.34 0.22 0.33 5.00
173 INT310474 Positive_regulation of Gene_expression of Fate1 1 0.04 0.07 0.33 5.00
174 INT258759 Regulation of Localization of ADHD1 3 0.38 4.71 0.32 5.00
175 INT121087 Gene_expression of Pde7a 3 0.17 2.69 0.31 5.00
176 INT229156 Gene_expression of Rsad2 1 0.02 0 0.28 5.00
177 INT261273 Negative_regulation of Pde6a 5 0.02 1.11 0.28 5.00
178 INT274774 Regulation of RRM1 2 0.16 0.07 0.27 5.00
179 INT129470 Regulation of RRM2 4 0.22 0.36 0.27 5.00
180 INT49311 Binding of Hprt 3 0.26 0.95 0.26 5.00
181 INT183429 Localization of Pde5a 5 0.56 1.61 0.25 5.00
182 INT101742 Regulation of Cacna1c 3 0.22 1.35 0.23 5.00
183 INT202338 Positive_regulation of Mtap2 6 0.32 1.11 0.23 5.00
184 INT172109 Gene_expression of SLC26A3 4 0.53 2.28 0.23 5.00
185 INT310464 Positive_regulation of Fate1 1 0.04 0.1 0.22 5.00
186 INT310476 Negative_regulation of Gene_expression of Neurog2 1 0.40 0.71 0.21 5.00
187 INT261276 Positive_regulation of Positive_regulation of Pde5a 1 0.26 0.07 0.21 5.00
188 INT310478 Positive_regulation of Transcription of Eomes 1 0.23 0.42 0.19 5.00
189 INT310466 Positive_regulation of Positive_regulation of Eomes 1 0.23 0.42 0.19 5.00
190 INT310483 Positive_regulation of Eomes 2 0.38 0.85 0.19 5.00
191 INT216106 Positive_regulation of Gene_expression of Imraq1 6 0.05 2 0.19 5.00
192 INT177609 Negative_regulation of GREM1 4 0.06 1.73 0.19 5.00
193 INT170390 Transcription of Eomes 2 0.31 0.51 0.18 5.00
194 INT302708 Negative_regulation of Spnb4 1 0.19 1 0.18 5.00
195 INT310492 Transcription of Dlx2 1 0.63 0.09 0.18 5.00
196 INT310468 Regulation of Gene_expression of Dlx2 1 0.42 0.1 0.18 5.00
197 INT261275 Negative_regulation of Localization of Pde5a 2 0.31 1.11 0.18 5.00
198 INT310462 Positive_regulation of Gene_expression of Ascl1 1 0.37 0.52 0.17 5.00
199 INT229143 Positive_regulation of Transcription of Tg(CAG-EGFP)D4Nagy 1 0.19 0.1 0.17 5.00
200 INT310480 Gene_expression of Tbr1 1 0.44 0.43 0.17 5.00
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