D:Sulfhemoglobinemia

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pChart

Disease Term
Synonyms Sulfhemoglobinemias
Documents 7
Hot Single Events 0
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Sulfhemoglobinemia. They are ordered first by their relevance to Sulfhemoglobinemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT49397 Binding of SHB and MHB 1 0.27 0.15 0.6 75.00
2 INT49398 Positive_regulation of Binding of SHB and MHB 1 0.36 0.15 0.6 75.00
3 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 0.08 1.14 0.37 5.00
4 INT229332 BAS Negative_regulation of Pck1 1 0.01 0.2 0.28 5.00
5 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16 5.00
6 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13 5.00
7 INT229287 BAS Negative_regulation of CRP 1 0.04 0.36 0.11 5.00
8 INT229274 BAS Positive_regulation of BAS Negative_regulation of FXR1 1 0.00 0.55 0.09 5.00
9 INT229286 BAS Negative_regulation of FXR1 1 0.02 0.55 0.09 5.00
10 INT229330 Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK 1 0.01 0.62 0.07 5.00
11 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07 5.00
12 INT229291 BAS Positive_regulation of HSD11B1 1 0.09 0.22 0.06 5.00
13 INT229275 Binding of FXR1 and BAS Negative_regulation of FXR1 1 0.00 0.59 0.05 5.00
14 INT229285 BAS Negative_regulation of FGF19 1 0.07 0.33 0.05 5.00
15 INT229288 Binding of FXR1 and BAS 1 0.01 0.59 0.05 5.00
16 INT229329 NR0B2 Negative_regulation of Nr1h2 1 0.03 0.58 0.05 5.00
17 INT229331 Binding of FXR1 and Nr1h2 1 0.02 0.61 0.05 5.00
18 INT229293 Positive_regulation of FXR1 Positive_regulation of Gene_expression of NR0B2 1 0.02 0.59 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Sulfhemoglobinemia. They are ordered first by their pain relevance and then by number of times they were reported in Sulfhemoglobinemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT11837 Positive_regulation of MHB 8 0.69 1.07 5.55 75.00
2 INT11838 Gene_expression of MHB 3 0.52 0.38 1.2 75.00
3 INT49400 Gene_expression of SHB 2 0.63 0.38 0.56 75.00
4 INT57728 Regulation of LDLR 25 0.41 13.18 3.46 40.56
5 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
6 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
7 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
8 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 5.00
9 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
10 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 5.00
11 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 5.00
12 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 5.00
13 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 5.00
14 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4 5.00
15 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 5.00
16 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 5.00
17 INT176173 Positive_regulation of Nr1h2 19 0.52 10.95 1.88 5.00
18 INT8667 Localization of HSD11B1 22 0.73 22.74 1.25 5.00
19 INT229302 Positive_regulation of FXR1 1 0.14 3.36 1.15 5.00
20 INT59179 Positive_regulation of GRHPR 5 0.14 2.57 1.09 5.00
21 INT183903 Binding of BAS 2 0.06 2.14 1.06 5.00
22 INT42210 Positive_regulation of TSHB 6 0.49 3.48 1.01 5.00
23 INT183902 Gene_expression of BAS 4 0.31 1.06 0.98 5.00
24 INT229328 Negative_regulation of FXR1 1 0.12 2.67 0.96 5.00
25 INT229278 Positive_regulation of Cby1 5 0.67 8.07 0.85 5.00
26 INT229306 Positive_regulation of BAS 4 0.23 2 0.84 5.00
27 INT197010 Positive_regulation of CYP7A1 4 0.47 1.75 0.7 5.00
28 INT229326 Negative_regulation of CYP7A1 3 0.29 1.03 0.7 5.00
29 INT176180 Negative_regulation of Nr1h2 6 0.16 7.47 0.69 5.00
30 INT229282 Binding of Nr1h2 7 0.17 5.11 0.66 5.00
31 INT229305 Gene_expression of FXR1 1 0.13 3.26 0.63 5.00
32 INT229276 Negative_regulation of Pck1 4 0.54 4.56 0.51 5.00
33 INT229307 Positive_regulation of Negative_regulation of CYP7A1 1 0.31 0.1 0.43 5.00
34 INT229308 Positive_regulation of Gene_expression of FXR1 1 0.10 1.39 0.41 5.00
35 INT229304 Gene_expression of FGF19 1 0.44 1.13 0.36 5.00
36 INT229284 Positive_regulation of Pck1 6 0.43 1.24 0.35 5.00
37 INT229279 Negative_regulation of Cby1 15 0.42 9.4 0.31 5.00
38 INT107752 Negative_regulation of HSD17B1 1 0.32 0.74 0.26 5.00
39 INT229321 Negative_regulation of Gene_expression of FXR1 1 0.08 0.23 0.25 5.00
40 INT229317 Gene_expression of SLC2A4 10 0.69 6.88 0.2 5.00
41 INT229301 Gene_expression of NR0B2 3 0.18 3.49 0.16 5.00
42 INT173171 Gene_expression of CYP7A1 2 0.45 1.02 0.14 5.00
43 INT229327 Positive_regulation of Positive_regulation of FXR1 1 0.10 0.92 0.11 5.00
44 INT229318 Positive_regulation of Gene_expression of NR0B2 1 0.12 1.17 0.09 5.00
45 INT222959 Positive_regulation of Gene_expression of PLIN2 2 0.09 0.67 0.08 5.00
46 INT222962 Gene_expression of PLIN2 2 0.10 0.67 0.08 5.00
47 INT229280 Negative_regulation of Binding of Nr1h2 1 0.10 1.14 0.08 5.00
48 INT229310 Regulation of BAS 1 0.07 0.41 0.08 5.00
49 INT229319 Regulation of Positive_regulation of CYP7A1 1 0.30 0.42 0.08 5.00
50 INT229283 Negative_regulation of Positive_regulation of Cby1 1 0.42 0.18 0.07 5.00
51 INT229314 Positive_regulation of Gene_expression of BAS 2 0.08 0.55 0.07 5.00
52 INT229320 Positive_regulation of Gene_expression of GCK 1 0.05 0.48 0.06 5.00
53 INT229324 Gene_expression of GCK 3 0.35 0.48 0.06 5.00
54 INT229303 Localization of FXR1 1 0.14 0.6 0.05 5.00
55 INT229309 Binding of FXR1 1 0.07 0.58 0.05 5.00
56 INT229311 Negative_regulation of NR0B2 1 0.14 0.58 0.05 5.00
57 INT229316 Negative_regulation of FGF19 1 0.25 0.38 0.05 5.00
58 INT229325 Positive_regulation of Gene_expression of CYP7A1 1 0.34 0.6 0.05 5.00
59 INT229281 Positive_regulation of Binding of Nr1h2 1 0.12 0.56 0.04 5.00
60 INT229312 Negative_regulation of Gene_expression of FGF19 1 0.33 0.39 0.04 5.00
61 INT229315 Regulation of Gene_expression of FGF19 1 0.26 0.39 0.04 5.00
62 INT229277 Positive_regulation of Positive_regulation of Nr1h2 1 0.12 0.54 0.03 5.00
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