D:Suppuration

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pChart

Disease Term
Synonyms PUS
Documents 908
Hot Single Events 44
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Suppuration. They are ordered first by their relevance to Suppuration and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 82.80
2 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05 5.00
3 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72 5.00
4 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72 5.00
5 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66 5.00
6 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34 5.00
7 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22 5.00
8 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22 5.00
9 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21 5.00
10 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 0.00 0.87 0.2 5.00
11 INT175909 Binding of ROS1 and CNBP 1 0.01 1.78 0.19 5.00
12 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19 5.00
13 INT174901 Binding of GSPT2 and GTSE1 1 0.01 1.28 0.07 5.00
14 INT270330 Binding of HYAL1 and TIMP1 1 0.00 0.2 0.04 5.00
15 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03 5.00
16 INT208152 Binding of CDK4 and MDM2 1 0.01 1.11 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Suppuration. They are ordered first by their pain relevance and then by number of times they were reported in Suppuration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4396 Negative_regulation of LGALS1 2 0.51 6.32 0.14 98.88
2 INT103655 Positive_regulation of TBC1D1 1 0.40 2.1 0.08 98.32
3 INT259688 Positive_regulation of Localization of TNFAIP8L2 1 0.04 1.14 0.19 98.04
4 INT18114 Gene_expression of NPC1 45 0.66 57.85 1.44 97.84
5 INT49235 Localization of DNASE1 7 0.81 1.69 1.04 97.46
6 INT49233 Regulation of Localization of DNASE1 2 0.44 0.99 0.27 97.46
7 INT289338 Gene_expression of Rnd1 1 0.10 0.34 0.3 97.20
8 INT40007 Regulation of DNASE1 4 0.44 2.98 0.53 97.02
9 INT150395 Binding of MEFV 55 0.44 31.18 3.42 96.92
10 INT149669 Positive_regulation of MEFV 12 0.46 14.17 2.07 96.82
11 INT322217 Negative_regulation of Gene_expression of SCGB1D4 1 0.06 0.5 0.05 96.64
12 INT259690 Localization of TNFAIP8L2 2 0.06 1.94 0.51 96.48
13 INT92235 Gene_expression of SCGB1D4 2 0.29 2.03 0.79 96.16
14 INT129227 Binding of DNASE1 4 0.14 2.54 0.54 95.20
15 INT103585 Gene_expression of MANEA 4 0.75 2.12 0.31 95.16
16 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 94.16
17 INT36132 Negative_regulation of pid 12 0.43 15.15 1.73 94.16
18 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 93.60
19 INT14515 Positive_regulation of Lrrc23 8 0.28 8.51 0.97 93.60
20 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 92.88
21 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 92.84
22 INT546 Binding of ALB 311 0.48 85.98 60.14 92.64
23 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 91.52
24 INT70654 Gene_expression of Actg2 27 0.67 18.62 4.79 91.24
25 INT70760 Positive_regulation of Actg2 8 0.48 6.23 0.61 91.24
26 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 89.08
27 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 89.08
28 INT3811 Negative_regulation of PAEP 36 0.50 23.7 5.18 88.36
29 INT76227 Binding of NPC1 30 0.41 32.31 4.05 85.64
30 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 83.60
31 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 83.60
32 INT83911 Negative_regulation of Gene_expression of SERPINA1 3 0.43 5.2 2.07 83.60
33 INT39413 Negative_regulation of SNRPB 7 0.31 2.57 2.36 83.44
34 INT192674 Positive_regulation of Gene_expression of Dync1h1 1 0.32 1.67 0 82.80
35 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 82.64
36 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 82.40
37 INT177586 Positive_regulation of Gene_expression of MRI1 9 0.33 4.97 2.91 82.40
38 INT282011 Transcription of LGALS1 1 0.67 2.47 0 82.28
39 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 81.84
40 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 81.76
41 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 81.32
42 INT27660 Binding of CFP 21 0.40 12.47 3.51 81.20
43 INT94668 Negative_regulation of Binding of FN1 5 0.58 4.44 0.18 80.80
44 INT61500 Binding of FN1 39 0.48 27.33 3.13 80.32
45 INT89925 Gene_expression of NR1I2 22 0.75 9.63 4.21 78.36
46 INT175997 Localization of HEPACAM 6 0.31 5.91 0.39 76.28
47 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 75.08
48 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 74.96
49 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 74.60
50 INT180035 Positive_regulation of Gene_expression of Chdh 2 0.22 8.21 5.78 74.60
51 INT2116 Negative_regulation of VSX1 29 0.36 10.67 1.89 74.32
52 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 73.88
53 INT56221 Regulation of MPO 8 0.61 8.44 1.84 73.88
54 INT179169 Transcription of IL13 11 0.15 4.22 1.37 72.48
55 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66 72.08
56 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 71.84
57 INT56299 Transcription of IL4 15 0.64 10.2 5.44 71.68
58 INT4047 Binding of F13A1 105 0.43 66.54 11.81 70.96
59 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 70.60
60 INT73330 Positive_regulation of SERPINB2 6 0.47 5.33 1.57 70.16
61 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 70.00
62 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 69.84
63 INT18773 Localization of ALB 117 0.80 69.18 13.8 68.48
64 INT263636 Binding of FAM83H 1 0.01 0.27 0 68.48
65 INT63177 Regulation of HP 71 0.44 39.48 5.86 68.24
66 INT17052 Binding of SERPINB2 4 0.43 4.89 1.32 65.20
67 INT153297 Regulation of MEFV 6 0.40 11.09 0.71 65.08
68 INT251 Regulation of INS 398 0.62 232.47 55.04 64.72
69 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 64.40
70 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 64.12
71 INT5345 Positive_regulation of BRD2 14 0.67 6.72 3.43 64.12
72 INT53594 Binding of Csrp1 5 0.32 11.87 3.84 62.32
73 INT183148 Regulation of Binding of HEY 1 0.26 1.73 0.42 62.32
74 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88 61.44
75 INT100861 Binding of CRP 179 0.48 175.2 26.45 59.12
76 INT183146 Binding of HEY 1 0.21 1.67 0.41 58.52
77 INT16214 Localization of F13A1 36 0.74 21.8 4.87 56.60
78 INT174653 Localization of MEFV 15 0.70 12.06 1.93 54.72
79 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 53.20
80 INT19590 Localization of cod 2 0.17 0.27 0.09 52.84
81 INT37480 Binding of BTS1 2 0.36 0.8 0.19 52.40
82 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 50.24
83 INT154706 Gene_expression of Tg 9 0.38 4.95 0.64 48.24
84 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 47.52
85 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 47.20
86 INT76125 Transcription of CD40LG 5 0.55 2.66 0.18 47.20
87 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 44.96
88 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 41.88
89 INT260738 Gene_expression of Ugt1a2 2 0.02 2.22 0.5 40.72
90 INT266625 Positive_regulation of Gene_expression of Ugt1a2 1 0.01 0.97 0.25 40.72
91 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 40.20
92 INT263637 Gene_expression of FAM83H 1 0.01 0 0 39.84
93 INT266626 Binding of Ugt1a2 1 0.00 1.35 0.04 33.88
94 INT24815 Binding of LDHA 9 0.36 6.73 0.89 33.52
95 INT342587 Regulation of Binding of LDHA 1 0.44 1.12 0.04 33.52
96 INT266627 Positive_regulation of Ugt1a2 3 0.04 5.54 0.56 33.24
97 INT93789 Gene_expression of Tnnc1 28 0.76 17.3 1.99 31.84
98 INT8518 Localization of Ifng 53 0.81 36.68 24.13 31.76
99 INT2117 Regulation of VSX1 15 0.30 3.38 3.38 30.20
100 INT61366 Positive_regulation of NFASC 16 0.26 13.75 4.11 27.20
101 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 25.00
102 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 25.00
103 INT25608 Regulation of Gene_expression of Il1 37 0.44 27.76 10.1 25.00
104 INT241081 Localization of PUJO 1 0.60 0.52 0.03 21.60
105 INT83607 Positive_regulation of CSAD 13 0.59 14.24 8.07 19.60
106 INT163489 Binding of CDH1 13 0.19 8.63 0.35 17.48
107 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 16.88
108 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 15.52
109 INT155590 Gene_expression of ARIH1 8 0.58 10.76 0.24 15.00
110 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 14.60
111 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 14.12
112 INT113676 Gene_expression of NRP1 22 0.72 10.81 1.71 12.60
113 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 11.92
114 INT156997 Localization of NPC1 19 0.64 30 0.42 11.28
115 INT183144 Positive_regulation of Localization of MEFV 2 0.42 2.61 0.51 9.76
116 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 8.04
117 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 6.64
118 INT158 Localization of Prl 2431 0.81 378.96 952.2 5.00
119 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
120 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
121 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
122 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
123 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
124 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
125 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
126 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 5.00
127 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
128 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
129 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 5.00
130 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 5.00
131 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
132 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
133 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 5.00
134 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
135 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
136 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
137 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
138 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
139 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
140 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
141 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 5.00
142 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
143 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 5.00
144 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
145 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
146 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 5.00
147 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
148 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
149 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
150 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
151 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
152 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 5.00
153 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 5.00
154 INT19775 Localization of Il1 183 0.78 145.5 50.91 5.00
155 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 5.00
156 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
157 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
158 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
159 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
160 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
161 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
162 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
163 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
164 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 5.00
165 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84 5.00
166 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
167 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
168 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
169 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
170 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
171 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 5.00
172 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
173 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
174 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
175 INT90792 Localization of Il10 144 0.80 87.88 30.03 5.00
176 INT894 Binding of Avp 84 0.48 29.16 29.63 5.00
177 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
178 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
179 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
180 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 5.00
181 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
182 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
183 INT36428 Binding of Chdh 42 0.47 48.04 26.54 5.00
184 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
185 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 5.00
186 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
187 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 5.00
188 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27 5.00
189 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 5.00
190 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7 5.00
191 INT134651 Binding of TLR4 89 0.48 66.96 23.19 5.00
192 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
193 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 5.00
194 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 5.00
195 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
196 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79 5.00
197 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 5.00
198 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 5.00
199 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 5.00
200 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
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