D:Sweet's Syndrome

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pChart

Disease Term
Synonyms Acute Febrile Neutrophilic Dermatosis, Dermatosis Neutrophilic Febrile Acute, Neutrophilic Dermatosis Acute Febrile, SWEET S SYNDROME, Sweet Syndrome, Sweets Syndrome, SYNDROME SWEET S
Documents 66
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Sweet's Syndrome. They are ordered first by their relevance to Sweet's Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05 37.60
2 INT342887 Binding of IFNG and IFNGR1 1 0.02 0.65 0.05 32.92
3 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5 5.00
4 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04 5.00
5 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0 5.00
6 INT241537 Negative_regulation of Binding of Abl1 and Src 1 0.04 0.14 0 5.00
7 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0 5.00
8 INT241534 Binding of Abl1 and Src 1 0.04 0.14 0 5.00
9 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Sweet's Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Sweet's Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 91.68
2 INT22094 Negative_regulation of CTSG 2 0.42 0.95 1.04 90.40
3 INT22091 Negative_regulation of SERPINA3 3 0.26 2.51 0.46 90.40
4 INT22093 Gene_expression of CTSG 1 0.75 0.66 0.16 87.84
5 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 87.32
6 INT22092 Gene_expression of SERPINA3 17 0.75 11.57 3.16 86.64
7 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 76.32
8 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 75.00
9 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 75.00
10 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 67.92
11 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 50.00
12 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 50.00
13 INT14690 Localization of CSF2 124 0.80 85.17 27.26 50.00
14 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 50.00
15 INT72747 Localization of IgG 55 0.53 30.88 4.19 50.00
16 INT329699 Positive_regulation of HMHA1 1 0.04 1.56 0.09 50.00
17 INT756 Gene_expression of C3 138 0.75 100.6 19.2 38.84
18 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 38.84
19 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48 33.52
20 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 33.48
21 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 33.48
22 INT342889 Gene_expression of IFNGR1 1 0.28 0.65 0.05 33.48
23 INT83735 Gene_expression of Foxm1 41 0.77 22.9 5.07 23.04
24 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 16.60
25 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
26 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
27 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
28 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
29 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 5.00
30 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
31 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
32 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
33 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
34 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
35 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
36 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
37 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
38 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 5.00
39 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
40 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
41 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
42 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
43 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
44 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
45 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 5.00
46 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
47 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
48 INT6993 Negative_regulation of Mpo 72 0.59 61.83 19.51 5.00
49 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22 5.00
50 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97 5.00
51 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
52 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82 5.00
53 INT25613 Gene_expression of Il1f5 32 0.77 13.29 10.44 5.00
54 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 5.00
55 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
56 INT149138 Binding of PDX1 27 0.37 32.62 9.33 5.00
57 INT51530 Negative_regulation of Adk 11 0.56 3.83 9.07 5.00
58 INT25381 Localization of Csf2 62 0.76 47.48 9.03 5.00
59 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 5.00
60 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12 5.00
61 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 5.00
62 INT55513 Binding of Foxm1 19 0.37 2.37 5.54 5.00
63 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
64 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06 5.00
65 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 5.00
66 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
67 INT130295 Gene_expression of Abcg2 21 0.75 9.75 3.42 5.00
68 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
69 INT569 Negative_regulation of C4a 13 0.42 9.48 2.85 5.00
70 INT50335 Positive_regulation of Foxm1 20 0.69 5.11 2.81 5.00
71 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57 5.00
72 INT191017 Localization of Cd79a 28 0.56 13.94 2.55 5.00
73 INT102659 Gene_expression of CSF3 32 0.77 21.93 2.39 5.00
74 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38 5.00
75 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37 5.00
76 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23 5.00
77 INT34644 Binding of HLA-C 19 0.47 9.41 2.2 5.00
78 INT99572 Localization of Kit 13 0.75 5.23 1.95 5.00
79 INT146943 Gene_expression of Src 13 0.49 6.65 1.65 5.00
80 INT25384 Positive_regulation of Localization of Csf2 11 0.66 7.81 1.62 5.00
81 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 5.00
82 INT164325 Negative_regulation of Abcg2 6 0.39 1.88 1.2 5.00
83 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1 5.00
84 INT118054 Regulation of ARMC9 23 0.34 11.32 1.06 5.00
85 INT164324 Negative_regulation of Gene_expression of Abcg2 4 0.45 1.03 0.99 5.00
86 INT274238 Positive_regulation of AIP 2 0.42 8.14 0.97 5.00
87 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 5.00
88 INT193019 Positive_regulation of Positive_regulation of SMUG1 6 0.39 4.7 0.83 5.00
89 INT206007 Positive_regulation of Localization of Cd79a 5 0.35 3.32 0.81 5.00
90 INT241499 Binding of Abl1 23 0.47 8.86 0.75 5.00
91 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75 5.00
92 INT148291 Positive_regulation of CSF3 9 0.61 6.37 0.7 5.00
93 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68 5.00
94 INT25602 Positive_regulation of THPO 5 0.69 4.55 0.57 5.00
95 INT206006 Negative_regulation of Gene_expression of Foxm1 4 0.43 2.63 0.56 5.00
96 INT159864 Localization of CYP3A5 2 0.73 0.33 0.52 5.00
97 INT206009 Transcription of Foxm1 2 0.68 1.49 0.51 5.00
98 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43 5.00
99 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42 5.00
100 INT144021 Binding of Pdgfrb 9 0.37 5.53 0.28 5.00
101 INT212362 Positive_regulation of Gene_expression of CSF3 3 0.32 4.85 0.26 5.00
102 INT241498 Regulation of Abl1 8 0.32 6.46 0.22 5.00
103 INT140680 Negative_regulation of DYNLT1 1 0.29 0.93 0.18 5.00
104 INT199561 Positive_regulation of Gene_expression of Abl1 8 0.36 4.77 0.16 5.00
105 INT200802 Regulation of Jak2 5 0.61 2.86 0.16 5.00
106 INT241504 Negative_regulation of Aurka 2 0.09 1.54 0.11 5.00
107 INT241512 Phosphorylation of Abl1 4 0.59 2.68 0.09 5.00
108 INT241515 Negative_regulation of Phosphorylation of Abl1 3 0.30 1.36 0.09 5.00
109 INT175415 Negative_regulation of COX10 5 0.07 3.33 0.08 5.00
110 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05 5.00
111 INT241507 Positive_regulation of Abl1 5 0.40 2.69 0.05 5.00
112 INT241506 Localization of Abl1 2 0.54 2.37 0.04 5.00
113 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03 5.00
114 INT225256 Positive_regulation of Gene_expression of Src 3 0.20 0.75 0 5.00
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