D:Syndactyly
From wiki-pain
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Molecular Interactions
The table below shows the top 200 pain related interactions that have been reported for Syndactyly. They are ordered first by their relevance to Syndactyly and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.
Int No | Page link | Interaction String | Documents | TM Confidence | Disease Relevance | Overall Pain Relevance | Term Relevance |
---|---|---|---|---|---|---|---|
1 | INT335887 | Akt1 Regulation of Lrp6 | 1 | 0.06 | 0.15 | 0 | 51.84 |
2 | INT335884 | Akt1 Regulation of Positive_regulation of Wnt5a | 1 | 0.03 | 0.15 | 0 | 50.64 |
3 | INT254433 | Binding of Lrp5 and Sost | 2 | 0.39 | 1.51 | 0.03 | 40.36 |
4 | INT335883 | Binding of Lrp6 and Wnt5a | 1 | 0.27 | 0.08 | 0 | 34.88 |
5 | INT335888 | Lrp5 Negative_regulation of Gene_expression of Tph1 | 1 | 0.22 | 0.15 | 0.21 | 5.00 |
6 | INT335886 | Binding of Sost and Lrp4 | 1 | 0.28 | 0.65 | 0.07 | 5.00 |
7 | INT335890 | Binding of Dkk1 and Lrp4 | 1 | 0.37 | 0.64 | 0.07 | 5.00 |
8 | INT335882 | Dkk1 Negative_regulation of Wnt2 | 1 | 0.02 | 0.15 | 0 | 5.00 |
9 | INT335891 | Binding of Dkk1 and Lrp5 | 1 | 0.39 | 0.57 | 0 | 5.00 |
Single Events
The table below shows the top 200 pain related interactions that have been reported for Syndactyly. They are ordered first by their pain relevance and then by number of times they were reported in Syndactyly. Please click on the 'INT' link to display more detailed information on each interaction.
Int No | Page link | Event String | Documents | TM Confidence | Disease Relevance | Overall Pain Relevance | Term Relevance |
---|---|---|---|---|---|---|---|
1 | INT297757 | Transcription of Lrp5 | 2 | 0.68 | 0.82 | 0 | 89.88 |
2 | INT297820 | Regulation of Transcription of Lrp5 | 2 | 0.44 | 0.83 | 0 | 89.88 |
3 | INT335866 | Regulation of Transcription of Lrp6 | 1 | 0.42 | 0.25 | 0 | 89.88 |
4 | INT335873 | Transcription of Lrp6 | 1 | 0.64 | 0.25 | 0 | 89.88 |
5 | INT335878 | Localization of Sost | 3 | 0.69 | 1.11 | 0.22 | 86.08 |
6 | INT213503 | Regulation of Wnt2 | 9 | 0.37 | 3.54 | 0.56 | 83.12 |
7 | INT297804 | Regulation of Lrp5 | 6 | 0.60 | 2.31 | 0.27 | 79.28 |
8 | INT335875 | Regulation of Lrp6 | 1 | 0.57 | 0.43 | 0.27 | 79.28 |
9 | INT111156 | Negative_regulation of Dkk1 | 21 | 0.58 | 20.08 | 4.27 | 74.32 |
10 | INT335876 | Negative_regulation of Sost | 11 | 0.51 | 6.77 | 0.67 | 69.92 |
11 | INT335868 | Negative_regulation of Gene_expression of Sost | 2 | 0.58 | 1.12 | 0.04 | 62.60 |
12 | INT335864 | Gene_expression of Sost | 4 | 0.77 | 2.36 | 0.2 | 61.88 |
13 | INT87022 | Gene_expression of Apc | 68 | 0.67 | 46.98 | 5.22 | 59.16 |
14 | INT335870 | Regulation of Gene_expression of Tnfrsf11b | 1 | 0.13 | 0.11 | 0 | 55.60 |
15 | INT123459 | Gene_expression of Tnfrsf11b | 35 | 0.58 | 24.16 | 7.26 | 55.04 |
16 | INT254426 | Gene_expression of Lrp5 | 5 | 0.67 | 3.28 | 0.06 | 51.92 |
17 | INT108519 | Binding of Lrp6 | 8 | 0.44 | 1.47 | 1.19 | 50.72 |
18 | INT254427 | Binding of Lrp5 | 10 | 0.48 | 5.43 | 0.26 | 50.72 |
19 | INT162576 | Positive_regulation of Wnt5a | 3 | 0.48 | 0.71 | 0.08 | 47.28 |
20 | INT335872 | Positive_regulation of Gene_expression of Lrp6 | 1 | 0.46 | 0.18 | 0 | 46.24 |
21 | INT335881 | Gene_expression of Lrp6 | 1 | 0.62 | 0.09 | 0 | 44.80 |
22 | INT335861 | Localization of Lrp6 | 1 | 0.69 | 0.54 | 0.17 | 41.76 |
23 | INT188047 | Positive_regulation of Wnt2 | 51 | 0.58 | 31.41 | 2.94 | 41.36 |
24 | INT201777 | Phosphorylation of Wnt2 | 2 | 0.03 | 1.31 | 0.05 | 41.36 |
25 | INT335865 | Positive_regulation of Phosphorylation of Lrp6 | 1 | 0.64 | 0.46 | 0.05 | 40.48 |
26 | INT335869 | Binding of Sost | 6 | 0.32 | 1.79 | 0.18 | 40.36 |
27 | INT335862 | Phosphorylation of Lrp6 | 1 | 0.76 | 0.37 | 0.05 | 39.36 |
28 | INT335880 | Regulation of Wnt5a | 1 | 0.32 | 0.07 | 0 | 27.12 |
29 | INT254429 | Negative_regulation of Lrp5 | 4 | 0.57 | 1.95 | 0.18 | 9.72 |
30 | INT124371 | Negative_regulation of Gsk3b | 170 | 0.55 | 87.92 | 15.51 | 5.00 |
31 | INT129883 | Gene_expression of Dkk1 | 56 | 0.77 | 45.42 | 12.52 | 5.00 |
32 | INT135372 | Positive_regulation of Gsk3b | 72 | 0.70 | 50.03 | 9.28 | 5.00 |
33 | INT167284 | Phosphorylation of Gsk3b | 88 | 0.82 | 36.03 | 4.21 | 5.00 |
34 | INT126659 | Gene_expression of Tph1 | 22 | 0.78 | 2.04 | 4.04 | 5.00 |
35 | INT198885 | Gene_expression of Lrp1 | 33 | 0.57 | 10.2 | 1.91 | 5.00 |
36 | INT242153 | Negative_regulation of Wnt2 | 19 | 0.49 | 11.87 | 1.37 | 5.00 |
37 | INT208536 | Positive_regulation of Positive_regulation of Gsk3b | 6 | 0.30 | 4.83 | 1.11 | 5.00 |
38 | INT165338 | Binding of Dkk1 | 4 | 0.37 | 3.64 | 1.04 | 5.00 |
39 | INT124374 | Binding of Wnt2 | 21 | 0.31 | 10.16 | 0.99 | 5.00 |
40 | INT182010 | Regulation of Tnfrsf11b | 2 | 0.18 | 1.13 | 0.67 | 5.00 |
41 | INT242137 | Negative_regulation of Positive_regulation of Gsk3b | 7 | 0.39 | 2.99 | 0.67 | 5.00 |
42 | INT245721 | Localization of FRZB | 6 | 0.78 | 4.3 | 0.6 | 5.00 |
43 | INT201524 | Localization of Wnt2 | 14 | 0.62 | 9.24 | 0.46 | 5.00 |
44 | INT277463 | Localization of Sfrp1 | 2 | 0.23 | 0.64 | 0.36 | 5.00 |
45 | INT335874 | Regulation of Lrp4 | 1 | 0.18 | 0 | 0.23 | 5.00 |
46 | INT312604 | Gene_expression of Lrp4 | 2 | 0.71 | 1.48 | 0.21 | 5.00 |
47 | INT335879 | Negative_regulation of Gene_expression of Tph1 | 1 | 0.19 | 0.15 | 0.21 | 5.00 |
48 | INT254428 | Binding of Lrp4 | 4 | 0.44 | 1.52 | 0.11 | 5.00 |
49 | INT335860 | Negative_regulation of Sfrp1 | 1 | 0.18 | 0.91 | 0.06 | 5.00 |
50 | INT335871 | Negative_regulation of Sfrp2 | 1 | 0.18 | 0.91 | 0.06 | 5.00 |
51 | INT335859 | Regulation of Sfrp1 | 1 | 0.08 | 0.43 | 0.03 | 5.00 |
52 | INT335867 | Positive_regulation of Negative_regulation of Sfrp2 | 1 | 0.14 | 0.49 | 0.03 | 5.00 |
53 | INT198907 | Positive_regulation of Gene_expression of Lrp1 | 7 | 0.49 | 3.2 | 0 | 5.00 |