D:Synovial Sarcoma

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Disease Term
Synonyms Sarcomas Synovial, Synovial Sarcomas, SYNOVIOMA, Synoviomas
Documents 150
Hot Single Events 119
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Synovial Sarcoma. They are ordered first by their relevance to Synovial Sarcoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT137252 BCL2L11 Regulation of NCAM1 1 0.20 0.99 0.08 99.98
2 INT137254 BCL2L11 Regulation of VIM 1 0.17 0.99 0.08 99.98
3 INT137251 BCL2L11 Regulation of CDH1 1 0.17 0.99 0.08 99.98
4 INT137255 BCL2L11 Regulation of SLC4A3 1 0.10 0.99 0.08 99.98
5 INT137256 BCL2L11 Regulation of SLC4A1 1 0.24 0.99 0.08 99.98
6 INT137253 BCL2L11 Regulation of CD99 1 0.23 0.99 0.08 99.98
7 INT265383 Hsp90aa1 Negative_regulation of HDAC9 1 0.06 0.7 0 99.08
8 INT305038 CD99 Regulation of DES 1 0.12 1.25 0 99.08
9 INT118227 Binding of ACTG2 and CD34 1 0.15 1.17 0.06 91.44
10 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11 63.28
11 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05 62.40
12 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05 61.52
13 INT296684 Binding of CD99 and Bcl2 1 0.01 1.68 0 59.40
14 INT250853 Binding of Fgf1 and Mtpn 1 0.00 0.28 0.21 13.52
15 INT137398 Binding of CD99 and Vim 2 0.02 2.36 0.09 11.24
16 INT296670 Binding of Bcl2 and Vim 1 0.00 1.31 0 11.24
17 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14 5.00
18 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89 5.00
19 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93 5.00
20 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84 5.00
21 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73 5.00
22 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68 5.00
23 INT327992 TRPV1 Positive_regulation of Gene_expression of ROS1 1 0.28 0.35 0.6 5.00
24 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54 5.00
25 INT250858 Mmp3 Regulation of Protein_catabolism of Ecm1 1 0.01 1.11 0.47 5.00
26 INT327995 Positive_regulation of TRPV1 Positive_regulation of Tnfrsf1a 1 0.16 0.63 0.46 5.00
27 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
28 INT327991 Positive_regulation of TRPV1 Positive_regulation of ROS1 1 0.26 0.2 0.4 5.00
29 INT250878 Il1a Positive_regulation of Fgf8 Positive_regulation of Ecm1 1 0.01 0.85 0.38 5.00
30 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38 5.00
31 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3 5.00
32 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28 5.00
33 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28 5.00
34 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23 5.00
35 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
36 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14 5.00
37 INT250857 Gene_expression of Mmp3 Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.17 0.13 5.00
38 INT250869 Mia Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.25 0.12 5.00
39 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1 5.00
40 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1 5.00
41 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09 5.00
42 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09 5.00
43 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0 5.00
44 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0 5.00
45 INT322413 Binding of ATF1 and EWSR1 1 0.26 1.3 0 5.00
46 INT353440 Rnd3 Positive_regulation of Rnd3 Negative_regulation of Rock1 1 0.24 0 0 5.00
47 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0 5.00
48 INT353439 Negative_regulation of Rock1 Negative_regulation of Hc3 1 0.08 0.2 0 5.00
49 INT353436 Rock1 Positive_regulation of Myo1f 1 0.02 0.23 0 5.00
50 INT353434 Binding of Rock1 and Rnd3 1 0.22 0.26 0 5.00
51 INT353435 Binding of Pdpk1 and Rock1 1 0.09 0.27 0 5.00
52 INT263899 Binding of PTPRC and TMED7-TICAM2 1 0.00 0.85 0 5.00
53 INT353438 Rnd3 Negative_regulation of Rock1 1 0.26 2.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Synovial Sarcoma. They are ordered first by their pain relevance and then by number of times they were reported in Synovial Sarcoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT109721 Gene_expression of Syt2 1 0.04 2.42 0.21 100.00
2 INT187793 Gene_expression of Csf1 10 0.77 22.35 0.66 99.92
3 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 99.84
4 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 99.84
5 INT264115 Positive_regulation of Ripk4 2 0.29 3.73 0.17 99.84
6 INT76477 Positive_regulation of CD99 14 0.50 14.77 1.42 99.80
7 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 99.80
8 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 99.80
9 INT15752 Positive_regulation of Ema 15 0.40 14.57 2.34 99.80
10 INT136395 Positive_regulation of Gene_expression of CD99 2 0.23 3.19 0.3 99.78
11 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 99.76
12 INT68269 Gene_expression of CD99 49 0.77 47.38 3.86 99.66
13 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34 99.48
14 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99 99.40
15 INT151343 Gene_expression of UBE2D1 2 0.56 3.48 0.15 99.26
16 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 99.08
17 INT321203 Negative_regulation of Localization of SYT1 1 0.01 1 0 99.00
18 INT321202 Localization of SYT1 1 0.01 1 0 99.00
19 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 98.96
20 INT153298 Localization of Syt2 1 0.00 0.72 0.07 98.96
21 INT93939 Binding of FBN1 4 0.33 4.05 0.67 98.92
22 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15 98.84
23 INT258949 Localization of OFD1 2 0.41 3.87 0 98.68
24 INT265369 Gene_expression of Ss18 1 0.12 3.81 0 98.64
25 INT93941 Gene_expression of SSX2 5 0.75 5.32 0.45 98.48
26 INT49610 Positive_regulation of Gene_expression of CTS 7 0.43 7.45 3.58 98.44
27 INT93938 Gene_expression of Setmar 1 0.02 0.71 0.14 98.36
28 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 98.28
29 INT127480 Negative_regulation of Hsp90aa1 20 0.57 10.67 0.56 98.20
30 INT258053 Positive_regulation of Negative_regulation of HDAC9 8 0.27 7.37 1.23 98.16
31 INT265380 Binding of SSX2 1 0.36 1.07 0 97.72
32 INT29637 Localization of KRT1 6 0.20 5.55 0.4 97.56
33 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 97.52
34 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 97.52
35 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 97.40
36 INT174112 Positive_regulation of Gene_expression of KRT19 4 0.44 4.28 0.31 97.36
37 INT232945 Positive_regulation of Gene_expression of KRT18 2 0.49 3.54 0.23 97.36
38 INT232967 Positive_regulation of Gene_expression of KRT8 2 0.29 3.54 0.23 97.36
39 INT71389 Positive_regulation of KRT19 3 0.38 4.91 0.13 97.36
40 INT220533 Positive_regulation of OFD1 2 0.27 6.58 0.08 97.36
41 INT258948 Positive_regulation of Gene_expression of OFD1 1 0.27 5.05 0 97.36
42 INT93937 Transcription of Setmar 1 0.02 0.75 0.14 97.28
43 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 97.18
44 INT164349 Positive_regulation of KRT8 2 0.10 3.14 0.08 97.00
45 INT258945 Positive_regulation of KRT18 2 0.21 4.52 0 97.00
46 INT191154 Binding of HDAC9 20 0.36 14.12 1.83 96.96
47 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 96.82
48 INT83479 Gene_expression of KRT18 30 0.65 27.29 1 96.66
49 INT258950 Gene_expression of OFD1 1 0.37 7.19 0 96.56
50 INT9473 Binding of MUC1 66 0.48 46.77 2.36 96.48
51 INT96188 Binding of Cd34 11 0.31 10.4 0.82 96.48
52 INT105884 Binding of Bcl2 19 0.35 15.67 3 96.48
53 INT37216 Binding of SMN1 11 0.36 6.66 1.86 96.48
54 INT128376 Binding of KIT 26 0.48 14.24 0.47 96.48
55 INT76479 Binding of CD99 5 0.33 4.66 0.44 96.48
56 INT73976 Gene_expression of Hsp90aa1 18 0.75 7.92 0.45 96.32
57 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2 95.92
58 INT338112 Positive_regulation of Gene_expression of Csf1 1 0.69 4.94 0.04 95.78
59 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36 95.76
60 INT265375 Negative_regulation of Hdac3 1 0.36 0.78 0 95.60
61 INT106097 Localization of pr 20 0.62 12.01 19.46 95.52
62 INT265379 Positive_regulation of Binding of HDAC9 2 0.19 1.06 0 95.08
63 INT265371 Binding of Hdac3 2 0.27 0.94 0 94.32
64 INT96189 Transcription of SS18 1 0.52 0.82 0.07 94.32
65 INT96190 Transcription of SSX2 1 0.52 0.82 0.07 94.32
66 INT272484 Negative_regulation of Myod1 8 0.39 6.77 0.2 94.20
67 INT304773 Negative_regulation of MYOG 1 0.02 2.35 0.07 94.20
68 INT23956 Negative_regulation of DES 12 0.42 10.84 1.82 94.20
69 INT265372 Localization of Hdac3 3 0.55 0.6 0.04 94.12
70 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 94.04
71 INT84894 Gene_expression of Calb2 45 0.73 24.65 7.81 94.04
72 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77 93.52
73 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 93.20
74 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 93.20
75 INT265377 Regulation of Runx1t1 1 0.01 0.89 0 92.16
76 INT83295 Positive_regulation of Cd68 21 0.39 14.55 2.46 91.92
77 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 91.60
78 INT89445 Gene_expression of MEPE 17 0.58 18.07 1.55 91.48
79 INT95636 Gene_expression of ACTG2 23 0.44 19.87 1.75 91.44
80 INT265374 Negative_regulation of Ss18 1 0.11 0.92 0 91.28
81 INT57699 Positive_regulation of CD1A 11 0.50 8.49 2.93 91.20
82 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 91.16
83 INT287298 Regulation of SS18 1 0.26 0.84 0 90.64
84 INT287296 Regulation of SSX2 1 0.26 0.84 0 90.64
85 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 90.48
86 INT86265 Binding of UBE2D1 5 0.38 3.85 0.22 90.44
87 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 89.52
88 INT21682 Binding of CD34 18 0.47 13.19 1.47 89.52
89 INT265376 Gene_expression of Hdac3 4 0.51 1.8 0.13 89.48
90 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 88.88
91 INT90240 Gene_expression of MYOG 19 0.75 10 1.06 88.88
92 INT116314 Gene_expression of Myod1 38 0.70 16.6 0.89 88.88
93 INT162518 Positive_regulation of Localization of Rela 12 0.47 1.96 2.41 88.84
94 INT93482 Localization of Rela 56 0.78 24.52 14.82 88.52
95 INT36200 Gene_expression of S100A1 9 0.77 9.56 0.75 88.40
96 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84 88.04
97 INT29441 Negative_regulation of Gene_expression of Cea 6 0.20 5.97 0.55 87.28
98 INT265373 Regulation of Hdac3 2 0.17 1.1 0.03 87.12
99 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 86.96
100 INT263905 Gene_expression of SLN 33 0.63 23.21 0.74 86.64
101 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 85.64
102 INT265378 Gene_expression of Ripk4 1 0.28 0.74 0 85.48
103 INT27935 Binding of Vim 21 0.36 15.65 2.61 85.44
104 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 85.40
105 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 84.64
106 INT79432 Positive_regulation of Calb2 7 0.23 6.59 0.61 84.56
107 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 84.56
108 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 84.52
109 INT140336 Negative_regulation of Csf1 3 0.43 3.64 0.36 84.20
110 INT181267 Gene_expression of USE1 12 0.32 7.6 2.7 83.88
111 INT250833 Localization of Fgf8 1 0.74 0.46 0.21 83.68
112 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2 83.08
113 INT250844 Localization of Fgf4 1 0.22 0.45 0.21 82.96
114 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17 82.88
115 INT149629 Gene_expression of Setmar 1 0.01 0.5 0.09 81.96
116 INT149630 Localization of Setmar 1 0.01 0.5 0.09 81.96
117 INT88070 Binding of Ema 7 0.18 7.39 0.31 81.68
118 INT131931 Binding of KRT7 13 0.36 19.24 0.5 81.68
119 INT320099 Protein_catabolism of STS 1 0.68 1.84 0 80.72
120 INT202476 Positive_regulation of Gene_expression of Rela 10 0.34 3.65 1.22 79.12
121 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42 78.72
122 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08 78.72
123 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 76.24
124 INT248323 Negative_regulation of Gene_expression of CD163 4 0.30 1.96 0 76.24
125 INT235060 Negative_regulation of Gene_expression of Csf1 1 0.42 2.56 0 76.24
126 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 75.00
127 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 75.00
128 INT156827 Localization of MRI1 25 0.65 16.06 8.33 74.72
129 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 74.64
130 INT302534 Localization of Mest 1 0.28 1.81 0 74.64
131 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 74.04
132 INT288060 Localization of Csf1 2 0.80 10.91 0.31 73.60
133 INT338110 Negative_regulation of Localization of Csf1 1 0.42 3 0 73.60
134 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33 72.80
135 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 70.56
136 INT99290 Positive_regulation of STS 16 0.43 6.96 0.75 69.00
137 INT36354 Localization of CTs 26 0.64 20.84 9.31 65.68
138 INT196188 Negative_regulation of Gene_expression of Mrgpre 2 0.58 3.12 1.34 63.32
139 INT250849 Binding of Fgfr4 1 0.11 0.54 0.19 63.28
140 INT196192 Gene_expression of Mrgpre 21 0.77 14.87 6.53 62.52
141 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 61.96
142 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 59.92
143 INT250836 Binding of Fgf8 3 0.35 0.66 0.24 59.04
144 INT257453 Positive_regulation of USE1 12 0.20 6.7 0.94 58.44
145 INT204924 Negative_regulation of Clta 1 0.01 1.37 0 54.64
146 INT196189 Positive_regulation of Mrgpre 3 0.46 3.34 0.34 54.60
147 INT47311 Gene_expression of Sts 12 0.58 11.02 0.44 51.00
148 INT193822 Regulation of Gene_expression of Sts 1 0.03 1.04 0 51.00
149 INT111143 Regulation of Gene_expression of KRT20 22 0.26 5.65 1.93 50.80
150 INT199308 Gene_expression of Krt8 37 0.75 23.17 1.06 50.72
151 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 50.00
152 INT93942 Gene_expression of SS18 3 0.75 0.44 0.1 50.00
153 INT93940 Positive_regulation of Syt10 3 0.19 0 0.03 50.00
154 INT92916 Gene_expression of Acta2 50 0.74 17.52 6.11 48.08
155 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 48.08
156 INT196190 Positive_regulation of Gene_expression of Mrgpre 2 0.50 1.37 0.36 47.04
157 INT63328 Binding of Fgf1 10 0.37 1.5 1.4 46.64
158 INT258947 Regulation of OFD1 1 0.25 3.47 0 43.76
159 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41 43.20
160 INT23955 Regulation of Vim 16 0.25 14.21 2.04 43.20
161 INT196003 Regulation of Cd34 4 0.30 3.38 0.5 43.20
162 INT96080 Regulation of UBE2D1 2 0.31 1.08 0.11 43.20
163 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21 42.92
164 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11 40.88
165 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 38.32
166 INT277164 Gene_expression of Cdh3 2 0.01 2.88 0.35 37.12
167 INT50077 Gene_expression of Myb 21 0.66 7.68 1.54 35.36
168 INT118124 Binding of USE1 24 0.16 16.64 5.44 32.52
169 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22 30.48
170 INT250851 Binding of Fgfr1 1 0.10 0.19 0.08 30.48
171 INT250839 Binding of Fgfr3 1 0.16 0.19 0.08 30.48
172 INT147796 Gene_expression of Ccndbp1 5 0.05 3.9 0.4 28.64
173 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 26.20
174 INT82686 Gene_expression of Sparc 4 0.75 6.14 2.34 18.40
175 INT139201 Localization of TP63 4 0.32 2.56 0.15 18.08
176 INT44872 Localization of Sts 5 0.64 5.2 0.2 17.08
177 INT141706 Localization of HLA-DRB1 9 0.75 4.87 0.48 13.92
178 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 10.64
179 INT94784 Binding of ROS1 113 0.40 71.57 10.26 10.64
180 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 5.00
181 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 5.00
182 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 5.00
183 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
184 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
185 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45 5.00
186 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
187 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 5.00
188 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
189 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
190 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
191 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 5.00
192 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 5.00
193 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 5.00
194 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
195 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 5.00
196 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 5.00
197 INT9664 Binding of LBP 127 0.48 94.9 63.42 5.00
198 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 5.00
199 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
200 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
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