D:Synovitis

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Disease Term
Synonyms Synovitides
Documents 1455
Hot Single Events 200
Hot Interactions 41

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Synovitis. They are ordered first by their relevance to Synovitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181899 TNF Regulation of ANGPT1 1 0.03 1.22 0.33 100.00
2 INT181893 TNF Regulation of ANGPT2 1 0.04 1.22 0.33 100.00
3 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33 100.00
4 INT224582 Binding of IL1B and Positive_regulation of Gene_expression of TNF 1 0.05 1.33 0.37 100.00
5 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28 99.36
6 INT227910 TNF Positive_regulation of Gene_expression of IL10 1 0.22 0.68 0.29 99.00
7 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24 98.60
8 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19 98.60
9 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 98.24
10 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8 97.80
11 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13 96.76
12 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15 96.72
13 INT258339 Binding of Aicda and Scara3 1 0.05 0.67 0.32 93.84
14 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15 93.12
15 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61 92.64
16 INT289246 Il6 Positive_regulation of Gopc 1 0.06 1 0.22 92.64
17 INT171874 Binding of SQLE and MRAP 1 0.00 1.29 0.35 92.44
18 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26 90.64
19 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25 90.16
20 INT182348 Binding of Cd3e and Crp 1 0.15 2.33 0.56 90.16
21 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25 89.96
22 INT182350 Binding of Ms4a1 and Crp 1 0.10 1.25 0.25 89.96
23 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74 89.04
24 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37 89.04
25 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37 89.04
26 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23 88.96
27 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36 88.84
28 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38 88.56
29 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15 88.56
30 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 88.28
31 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88 87.76
32 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88 87.76
33 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66 87.52
34 INT228497 Il4 Regulation of Ncoa5 1 0.01 1.24 0.57 87.20
35 INT289254 Il6 Regulation of Gene_expression of VEGFA 1 0.05 1.32 0.09 87.00
36 INT289257 Il6 Regulation of VEGFA 1 0.03 1.27 0.09 87.00
37 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15 84.32
38 INT250858 Mmp3 Regulation of Protein_catabolism of Ecm1 1 0.01 1.11 0.47 83.40
39 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19 82.72
40 INT299745 Binding of Masp1 and IgG 1 0.03 0.69 0.26 80.60
41 INT194595 Binding of TNFSF10 and TNFRSF10B 4 0.15 9.3 0.53 80.56
42 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48 79.80
43 INT194598 Binding of TNF and TNFRSF10B 1 0.02 1.52 0.08 79.56
44 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22 79.44
45 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26 78.32
46 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48 77.56
47 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 76.48
48 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 75.88
49 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 75.88
50 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 75.88
51 INT249624 Negative_regulation of Binding of CD86 and CTLA4 1 0.47 0.57 0.55 75.88
52 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 75.60
53 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 75.60
54 INT181560 Binding of Cd4 and Cd86 1 0.32 0.38 0.12 73.84
55 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44 73.68
56 INT224730 Fgf2 Positive_regulation of Gm2458 1 0.01 0.39 0.17 72.72
57 INT224732 VEGFA Positive_regulation of Gm2458 1 0.02 0.39 0.17 72.72
58 INT252296 TNF Regulation of Gene_expression of Il1 2 0.03 1.28 0.49 72.36
59 INT252294 TNF Regulation of Gene_expression of Il6 2 0.16 1.28 0.49 72.36
60 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35 71.76
61 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17 71.76
62 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 71.36
63 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52 71.08
64 INT171912 MAPK8IP3 Positive_regulation of MAPK9 1 0.06 0.78 0.26 71.08
65 INT171913 MAPK8 Positive_regulation of MAPK9 1 0.07 0.78 0.26 71.08
66 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52 69.92
67 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52 69.92
68 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52 69.92
69 INT171907 MAPK8 Positive_regulation of Gene_expression of MAPK14 1 0.06 0.77 0.26 69.92
70 INT171911 MAPK8IP3 Positive_regulation of Gene_expression of MAPK14 1 0.05 0.77 0.26 69.92
71 INT172140 CSF2 Positive_regulation of Gene_expression of TIMP1 1 0.07 0.72 0.27 69.20
72 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7 68.56
73 INT289255 Il6 Positive_regulation of Gene_expression of VEGFA 1 0.06 1.3 0.15 68.48
74 INT289256 Il6 Positive_regulation of VEGFA 1 0.05 1.3 0.15 68.48
75 INT252289 Il17a Positive_regulation of Gene_expression of Il1 1 0.02 0.75 0.34 68.00
76 INT252295 Il17a Positive_regulation of Gene_expression of TNF 1 0.03 0.75 0.34 68.00
77 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 65.72
78 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51 65.08
79 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51 65.08
80 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42 64.64
81 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98 64.44
82 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94 64.44
83 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 64.32
84 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 63.80
85 INT252326 Binding of Cx3cl1 and Klrk1 1 0.01 0.23 0.16 61.68
86 INT289250 Il6 Positive_regulation of Gene_expression of Timp1 1 0.11 0.64 0.03 58.56
87 INT323774 Binding of Il6 and OPA6 1 0.01 0.85 0.37 56.72
88 INT334061 Negative_regulation of Binding of TNFRSF11A and Tnfsf11 1 0.01 0.52 0.08 55.56
89 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 55.20
90 INT258343 Binding of Aicda and Kit 1 0.06 0.57 0.26 52.36
91 INT316713 Binding of Ddx41 and Pain1 1 0.00 0.94 0.28 51.44
92 INT328223 Mmp14 Regulation of Positive_regulation of Mmp13 1 0.07 0.69 0.29 44.64
93 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28 44.64
94 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 44.52
95 INT316676 Binding of CRX and SFTPD 1 0.05 0.65 0.33 42.88
96 INT172011 IgG Regulation of Ighm 1 0.00 0.77 0 42.12
97 INT352163 SNRPA Positive_regulation of Localization of IL10 1 0.06 0.87 0.23 41.88
98 INT250853 Binding of Fgf1 and Mtpn 1 0.00 0.28 0.21 41.56
99 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32 39.68
100 INT302818 Gcat Negative_regulation of Syk 1 0.00 0.53 0.24 39.52
101 INT329432 Binding of CCR6 and TH 1 0.00 0.47 0.23 39.40
102 INT329431 Binding of CCL20 and TH 1 0.00 0.47 0.23 39.40
103 INT312693 Binding of CCR6 and CCL20 2 0.34 2.33 0.53 37.12
104 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 36.12
105 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 35.12
106 INT260821 NRP2 Positive_regulation of Gene_expression of TNF 1 0.01 1.48 0.56 34.96
107 INT260830 Binding of NRP2 and Flt1 Positive_regulation of Gene_expression of TNF 1 0.01 1.5 0.56 34.96
108 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56 34.96
109 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65 34.92
110 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77 34.48
111 INT289245 Binding of Il6ra and Positive_regulation of Gene_expression of Ptger2 1 0.00 0.82 0.15 34.48
112 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76 34.44
113 INT178581 CNTN2 Positive_regulation of PTHLH 1 0.24 2.16 0.75 34.44
114 INT178577 CNTN2 Positive_regulation of IL2RA 1 0.03 2.16 0.75 34.44
115 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75 34.44
116 INT178575 CNTN2 Positive_regulation of PTHLH Positive_regulation of Positive_regulation of PTHLH 1 0.26 2.16 0.75 34.44
117 INT289247 Ptger2 Positive_regulation of Gene_expression of Tnfrsf11a 1 0.00 0.76 0.14 31.36
118 INT289242 Il6 Positive_regulation of Gene_expression of Prtn3 1 0.00 0.5 0.09 29.84
119 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22 29.36
120 INT289243 Il6 Positive_regulation of Prtn3 1 0.00 0.5 0.09 28.96
121 INT299787 Binding of IL2 and ISG20 1 0.04 0.82 0.21 28.16
122 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72 26.00
123 INT171976 Il18 Positive_regulation of Gene_expression of IFNA1 1 0.01 1.37 0.64 25.96
124 INT231750 LOC690550 Negative_regulation of Jak3 1 0.02 1.3 0.52 25.48
125 INT353020 Binding of CD80 and Positive_regulation of Gene_expression of CD28 1 0.13 0.35 0.34 24.76
126 INT355704 Binding of Cia1 and Aia1 1 0.00 1.85 0.77 23.52
127 INT231751 Binding of Il2rg and Jak3 1 0.03 1.56 0.67 22.96
128 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 22.24
129 INT248240 SDC3 Positive_regulation of Localization of CD68 1 0.05 0 0 19.68
130 INT182044 Binding of Proc and IgG 1 0.00 2.38 0.74 19.48
131 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11 16.08
132 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05 16.08
133 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05 16.08
134 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26 15.12
135 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07 14.72
136 INT289244 Binding of Il11ra1 and Il6ra 1 0.01 0.33 0.07 14.72
137 INT149121 Binding of CD80 and Cd28 2 0.04 0.95 0.46 9.40
138 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85 6.72
139 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
140 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
141 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
142 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
143 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
144 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
145 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
146 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
147 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
148 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49 5.00
149 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
150 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17 5.00
151 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14 5.00
152 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
153 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
154 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 5.00
155 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
156 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92 5.00
157 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
158 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
159 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69 5.00
160 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63 5.00
161 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61 5.00
162 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
163 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54 5.00
164 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
165 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53 5.00
166 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53 5.00
167 INT174450 Positive_regulation of Binding of Cxcr3 and Smcp 1 0.18 2.83 1.49 5.00
168 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
169 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
170 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
171 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
172 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 5.00
173 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33 5.00
174 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3 5.00
175 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27 5.00
176 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25 5.00
177 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
178 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 5.00
179 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21 5.00
180 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2 5.00
181 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2 5.00
182 INT184402 Binding of HLA-DRB4 and HLA-E 1 0.00 3.1 1.19 5.00
183 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18 5.00
184 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14 5.00
185 INT224728 Col7a1 Positive_regulation of Cia1 1 0.00 2.9 1.12 5.00
186 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 5.00
187 INT176474 Binding of CXCR3 and CXCL9 3 0.22 1.9 1.05 5.00
188 INT264324 Olr614 Regulation of IL-17 1 0.02 2.3 1.03 5.00
189 INT174451 Trav6-3 Regulation of Transcription of Cxcr3 1 0.06 1.86 1 5.00
190 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99 5.00
191 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99 5.00
192 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98 5.00
193 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98 5.00
194 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98 5.00
195 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97 5.00
196 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96 5.00
197 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94 5.00
198 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93 5.00
199 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93 5.00
200 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Synovitis. They are ordered first by their pain relevance and then by number of times they were reported in Synovitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
2 INT105021 Binding of GOPC 187 0.40 60.39 20.38 100.00
3 INT182338 Gene_expression of Glrb 11 0.51 14.26 5.1 100.00
4 INT171879 Binding of ENOX1 9 0.03 3.37 0.77 100.00
5 INT94744 Regulation of Transcription of Il1b 3 0.44 2.83 1.26 100.00
6 INT182344 Positive_regulation of Gene_expression of Glrb 1 0.38 2.92 0.74 100.00
7 INT128045 Positive_regulation of Per1 29 0.69 5.32 5.5 100.00
8 INT209567 Gene_expression of Ncoa5 4 0.05 4.81 1.78 100.00
9 INT209562 Negative_regulation of Gene_expression of Ncoa5 2 0.03 1.75 0.79 100.00
10 INT264336 Protein_catabolism of NCOA5 1 0.03 0.9 0.24 100.00
11 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 99.96
12 INT137049 Positive_regulation of Glrb 7 0.46 9.24 3.22 99.96
13 INT114873 Phosphorylation of Stat3 63 0.82 30.19 8.23 99.96
14 INT114871 Positive_regulation of Phosphorylation of Stat3 20 0.69 12.34 4.6 99.96
15 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 99.92
16 INT98131 Regulation of TNFRSF1A 5 0.31 5.28 0.76 99.92
17 INT98128 Positive_regulation of Regulation of TNFRSF1A 2 0.30 1.95 0.07 99.92
18 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 99.88
19 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 99.88
20 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.84
21 INT184065 Phosphorylation of Socs3 2 0.81 2.67 0.53 99.84
22 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 99.80
23 INT58449 Binding of Mthfd1 47 0.47 22.02 10.29 99.80
24 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 99.78
25 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93 99.76
26 INT73479 Positive_regulation of Hrec 21 0.04 16.16 6.87 99.76
27 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 99.72
28 INT188588 Localization of Mthfd1 20 0.49 9.19 4.37 99.72
29 INT153718 Gene_expression of ANGPT1 15 0.45 10.82 2.13 99.72
30 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88 99.72
31 INT58766 Gene_expression of ANGPT2 41 0.67 21.65 4.82 99.72
32 INT1901 Binding of Mefv 24 0.48 32.26 4.5 99.70
33 INT182337 Positive_regulation of Cd163 3 0.32 2.22 0.62 99.68
34 INT102549 Positive_regulation of Gene_expression of Cd68 3 0.49 2.72 1.96 99.68
35 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.64
36 INT96037 Positive_regulation of Localization of Nos2 2 0.49 0.78 0.52 99.64
37 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.62
38 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 99.54
39 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.54
40 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 99.52
41 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.52
42 INT142462 Positive_regulation of Gene_expression of Socs3 23 0.68 23.27 8.27 99.52
43 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 99.48
44 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34 99.48
45 INT258348 Positive_regulation of ANP32B 3 0.10 1.21 0.42 99.48
46 INT13170 Gene_expression of Comp 25 0.74 8.68 5.62 99.40
47 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 99.36
48 INT151160 Regulation of Mefv 2 0.39 1.36 0.25 99.36
49 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.34
50 INT142464 Gene_expression of Socs3 58 0.77 52.04 15.34 99.34
51 INT176445 Protein_catabolism of Gopc 23 0.76 7.57 0.75 99.34
52 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05 99.32
53 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 99.32
54 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58 99.28
55 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 99.20
56 INT2919 Negative_regulation of F8 47 0.59 23.48 5.1 99.18
57 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.16
58 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.10
59 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.10
60 INT102547 Gene_expression of Cd68 25 0.75 14.47 5.22 99.08
61 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 99.06
62 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 99.04
63 INT171134 Gene_expression of CD28 67 0.65 32.55 13.61 99.04
64 INT6484 Binding of IL1B 122 0.47 75.84 35.07 99.04
65 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99 99.04
66 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.00
67 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 99.00
68 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 99.00
69 INT49610 Positive_regulation of Gene_expression of CTS 7 0.43 7.45 3.58 99.00
70 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 98.96
71 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 98.92
72 INT181270 Protein_catabolism of GPSM2 1 0.31 0.42 0.19 98.92
73 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 98.88
74 INT69313 Regulation of Scn10a 5 0.60 4.45 3.14 98.88
75 INT29833 Binding of Spna1 39 0.27 19.4 1.74 98.88
76 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17 98.84
77 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 98.84
78 INT125884 Positive_regulation of CHI3L1 15 0.62 34.04 4.43 98.84
79 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 98.82
80 INT58632 Negative_regulation of Il1f5 3 0.13 3.5 0.96 98.82
81 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 98.80
82 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84 98.72
83 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 98.68
84 INT66926 Transcription of Il1b 15 0.69 13.16 7.81 98.68
85 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 98.68
86 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 98.68
87 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97 98.56
88 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 98.54
89 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 98.52
90 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5 98.52
91 INT22482 Negative_regulation of Gene_expression of CADM1 6 0.49 3.2 1.8 98.52
92 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 98.48
93 INT53590 Gene_expression of PRF1 33 0.58 23.46 10.02 98.48
94 INT258316 Binding of Aicda 1 0.30 2.24 1.08 98.48
95 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 98.44
96 INT120901 Positive_regulation of Gene_expression of Il13 36 0.57 31.63 13.36 98.44
97 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 98.44
98 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 98.44
99 INT181921 Binding of TEK 2 0.09 1.88 0.32 98.44
100 INT160080 Localization of Ecm1 6 0.15 4.86 2.36 98.34
101 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 98.32
102 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 98.32
103 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 98.32
104 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61 98.28
105 INT117519 Positive_regulation of Transcription of Ccl2 5 0.49 6.01 2.54 98.28
106 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 98.28
107 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 98.28
108 INT17049 Localization of CD4 57 0.75 35.33 6.89 98.20
109 INT133422 Binding of IL6ST 10 0.40 4.9 1.49 98.20
110 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 98.16
111 INT76581 Regulation of Negative_regulation of NOS1 14 0.45 7.49 4.4 98.16
112 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 98.12
113 INT132187 Gene_expression of Ecm1 14 0.21 8.12 3.52 98.12
114 INT174653 Localization of MEFV 15 0.70 12.06 1.93 98.08
115 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 98.04
116 INT302775 Negative_regulation of Gene_expression of Syk 1 0.27 0.84 0.48 98.04
117 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 98.00
118 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37 97.92
119 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25 97.92
120 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53 97.92
121 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.88
122 INT174517 Localization of AHI1 2 0.24 1.62 0.68 97.88
123 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 97.84
124 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45 97.80
125 INT220276 Negative_regulation of Msu 2 0.16 1.67 0.58 97.80
126 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49 97.78
127 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84 97.78
128 INT18856 Protein_catabolism of HBG1 3 0.50 2.57 0.21 97.76
129 INT69311 Gene_expression of Scn10a 31 0.78 15.54 14.64 97.72
130 INT278340 Gene_expression of Syk 7 0.51 4.92 2.09 97.72
131 INT220695 Positive_regulation of Gene_expression of Scn10a 2 0.10 2.06 0.7 97.72
132 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 97.64
133 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 97.64
134 INT22804 Positive_regulation of ALDOC 8 0.41 8.07 1.02 97.60
135 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 97.60
136 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16 97.60
137 INT22092 Gene_expression of SERPINA3 17 0.75 11.57 3.16 97.60
138 INT83887 Gene_expression of HMOX2 10 0.77 7.99 3.85 97.60
139 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9 97.56
140 INT207384 Gene_expression of Pgia1 3 0.14 18.55 6.87 97.52
141 INT316708 Positive_regulation of Gene_expression of Pgia1 1 0.12 11.52 4.19 97.52
142 INT73608 Localization of Nos2 21 0.75 9.58 5.05 97.44
143 INT11807 Gene_expression of Il2 266 0.78 112 64.97 97.32
144 INT160814 Gene_expression of Il6ra 15 0.07 9.61 1.73 97.28
145 INT289237 Positive_regulation of Il6ra 1 0.05 3.84 0.59 97.28
146 INT37208 Gene_expression of BW62 1 0.65 1.25 0.51 97.28
147 INT171878 Binding of SQLE 8 0.04 4 0.63 97.24
148 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 97.12
149 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 97.12
150 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 97.12
151 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 97.08
152 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 97.08
153 INT21610 Positive_regulation of ANGPT2 23 0.41 13.28 3.03 97.08
154 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 97.08
155 INT117080 Localization of Csrp1 6 0.42 7.23 3.09 97.04
156 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 97.04
157 INT2038 Localization of Esr1 104 0.79 40.12 13.27 97.04
158 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 97.00
159 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 96.96
160 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36 96.88
161 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 96.88
162 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 96.88
163 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 96.84
164 INT109078 Positive_regulation of ANGPT1 7 0.22 3.08 1.21 96.72
165 INT275940 Negative_regulation of Syk 3 0.39 2.08 0.95 96.72
166 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 96.68
167 INT14823 Gene_expression of MET 103 0.75 51.92 32.48 96.68
168 INT228465 Positive_regulation of Timp2 4 0.64 6.29 3.54 96.68
169 INT69395 Gene_expression of CNTN2 28 0.68 13.29 4.37 96.64
170 INT69392 Positive_regulation of Gene_expression of CNTN2 3 0.44 2.43 0.58 96.64
171 INT133549 Gene_expression of Il15 42 0.69 27.84 14.74 96.56
172 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 96.48
173 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 96.48
174 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01 96.48
175 INT123910 Gene_expression of CXCL16 5 0.49 3.81 2.82 96.48
176 INT183808 Regulation of Gene_expression of IL17A 6 0.42 4.12 2.01 96.44
177 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 96.40
178 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 96.40
179 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 96.32
180 INT264318 Gene_expression of Olr614 1 0.03 4.2 1.71 96.32
181 INT264314 Positive_regulation of Gene_expression of Olr614 1 0.02 1.44 0.43 96.32
182 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36 96.24
183 INT162792 Gene_expression of NOD1 19 0.71 6.11 2.71 96.24
184 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94 96.16
185 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 96.12
186 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 96.00
187 INT61949 Regulation of Nos2 74 0.58 34.08 16.7 95.96
188 INT11696 Gene_expression of HLA-A 50 0.78 41.25 14.1 95.96
189 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94 95.92
190 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 95.88
191 INT39262 Negative_regulation of Olr1735 2 0.57 1.12 0.82 95.84
192 INT258328 Gene_expression of Aicda 76 0.71 58.29 16.86 95.68
193 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 95.68
194 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 95.68
195 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 95.68
196 INT61547 Regulation of Fgf2 21 0.47 7.23 3.24 95.64
197 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 95.60
198 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5 95.60
199 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23 95.52
200 INT105694 Binding of SFTPD 11 0.46 8.47 2.45 95.52
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