D:Systemic Vasculitis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Systemic Vasculitides, VASCULITIDES SYSTEMIC, Vasculitis Systemic
Documents 31
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Systemic Vasculitis. They are ordered first by their relevance to Systemic Vasculitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27 31.00
2 INT321602 Binding of C4A and PRTN3 1 0.00 0.99 0.27 31.00
3 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51 19.56
4 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51 19.56
5 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
6 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
7 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26 5.00
8 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66 5.00
9 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48 5.00
10 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
11 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42 5.00
12 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42 5.00
13 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28 5.00
14 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26 5.00
15 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23 5.00
16 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22 5.00
17 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 5.00
18 INT180345 Binding of HLA-DMA and HLA-DRB4 1 0.00 1.51 0.12 5.00
19 INT180344 CYP2A6 Regulation of AMELX 1 0.01 2.01 0.05 5.00
20 INT180373 CYP2A6 Regulation of Cyp2d4 1 0.05 2.01 0.05 5.00
21 INT180372 CYP2A6 Regulation of Cyp1a2 1 0.03 2.02 0.05 5.00
22 INT180348 CYP2A6 Regulation of AIRE 1 0.01 2.01 0.05 5.00
23 INT180351 Binding of TNFRSF25 and ENAM 1 0.01 1.85 0 5.00
24 INT249666 Binding of CD81 and GOPC 1 0.06 1.31 0 5.00
25 INT249664 Binding of CD81 and CHCHD2 1 0.00 2.51 0 5.00
26 INT180349 Binding of AMELX and BTG3 1 0.00 0.56 0 5.00
27 INT180346 Binding of PRTN3 and SMN1 1 0.00 3.22 0 5.00
28 INT180347 Binding of PRTN3 and BTG3 1 0.00 1.9 0 5.00
29 INT214886 Binding of Atcay and FIP1L1 1 0.08 4.06 0 5.00
30 INT214885 Binding of PDGFRA and Atcay 1 0.08 4.05 0 5.00
31 INT180350 Binding of HLA-DMA and ENAM 1 0.00 1.85 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Systemic Vasculitis. They are ordered first by their pain relevance and then by number of times they were reported in Systemic Vasculitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 92.84
2 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 92.00
3 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 91.56
4 INT37122 Gene_expression of Prtn3 3 0.60 3.65 1.04 90.80
5 INT64468 Positive_regulation of Gene_expression of Prtn3 1 0.00 2.33 0.29 90.80
6 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 89.52
7 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 89.44
8 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 89.44
9 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 89.44
10 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 86.52
11 INT129358 Gene_expression of ELOVL1 23 0.66 29.39 2.83 86.40
12 INT24983 Binding of MPO 18 0.42 17.56 3.29 85.68
13 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 84.96
14 INT16992 Binding of Prtn3 2 0.06 1.5 1.12 76.08
15 INT47949 Positive_regulation of ELOVL1 19 0.42 29.78 3.3 64.00
16 INT144885 Gene_expression of AMELX 4 0.11 2.89 0.29 60.72
17 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 56.08
18 INT84700 Positive_regulation of HSP90B2P 34 0.67 30.22 4.07 54.64
19 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 51.24
20 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05 49.68
21 INT254369 Negative_regulation of COL18A1 2 0.16 1.61 0.61 49.04
22 INT37394 Localization of ecs 9 0.34 6.41 2.11 48.64
23 INT5160 Localization of PTAFR 61 0.80 42.6 19.16 48.48
24 INT142006 Positive_regulation of COL18A1 2 0.41 3.01 0.53 46.08
25 INT701 Localization of IGHE 87 0.80 40.5 10.62 44.40
26 INT254370 Gene_expression of THBS2 1 0.06 2.24 1 43.20
27 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 41.60
28 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 38.56
29 INT106807 Binding of Lama5 2 0.08 1.71 0.24 38.52
30 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 38.20
31 INT756 Gene_expression of C3 138 0.75 100.6 19.2 27.96
32 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 27.80
33 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 27.60
34 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 18.24
35 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 16.64
36 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 15.76
37 INT19134 Gene_expression of TPSAB1 16 0.66 11.61 2.48 8.00
38 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
39 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
40 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
41 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
42 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
43 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
44 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
45 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
46 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 5.00
47 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
48 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
49 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
50 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
51 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
52 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
53 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
54 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
55 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 5.00
56 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
57 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
58 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
59 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52 5.00
60 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
61 INT6230 Localization of Ddc 40 0.79 13.11 20.88 5.00
62 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75 5.00
63 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35 5.00
64 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
65 INT143230 Gene_expression of CRYGD 61 0.65 52.11 15.93 5.00
66 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
67 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 5.00
68 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 5.00
69 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9 5.00
70 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 5.00
71 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65 5.00
72 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 5.00
73 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 5.00
74 INT120828 Localization of CXCL10 29 0.68 18.01 12.17 5.00
75 INT92574 Gene_expression of CXCL5 51 0.78 24.87 11.89 5.00
76 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32 5.00
77 INT157466 Gene_expression of CX3CR1 14 0.76 20.6 10.76 5.00
78 INT19428 Gene_expression of MTRF1 42 0.08 27.17 10.43 5.00
79 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 5.00
80 INT94125 Gene_expression of Cd28 38 0.67 21.73 7.75 5.00
81 INT47811 Positive_regulation of Localization of Ddc 11 0.69 4 7.6 5.00
82 INT127691 Gene_expression of CXCL1 23 0.66 18.11 7.04 5.00
83 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 5.00
84 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 5.00
85 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 5.00
86 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 5.00
87 INT177467 Negative_regulation of MTRF1 22 0.05 11.84 5.57 5.00
88 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 5.00
89 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31 5.00
90 INT74447 Gene_expression of Vwf 39 0.76 21.96 4.66 5.00
91 INT133905 Gene_expression of Ncam1 24 0.78 10.2 4.62 5.00
92 INT65514 Gene_expression of Cyp1a2 25 0.77 6.12 4.6 5.00
93 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57 5.00
94 INT67279 Localization of PRTN3 11 0.50 14.18 4.3 5.00
95 INT127667 Positive_regulation of Localization of CXCL10 5 0.59 5.89 4.09 5.00
96 INT180338 Binding of Cyp2d4 12 0.47 6.87 4.09 5.00
97 INT1149 Binding of ecs 19 0.37 13.67 3.9 5.00
98 INT22838 Gene_expression of Fgg 26 0.25 19.9 3.88 5.00
99 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7 5.00
100 INT18920 Binding of Egf 24 0.48 9.43 3.57 5.00
101 INT130351 Positive_regulation of Vwf 18 0.59 5.99 3.48 5.00
102 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47 5.00
103 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
104 INT208588 Binding of CXCR2 11 0.48 6.43 2.68 5.00
105 INT72165 Gene_expression of CXCL6 8 0.52 4.76 2.6 5.00
106 INT180343 Negative_regulation of Negative_regulation of Cyp2d4 2 0.36 0.49 2.38 5.00
107 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36 5.00
108 INT65034 Regulation of Fgf1 7 0.61 2.42 2.34 5.00
109 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13 5.00
110 INT153718 Gene_expression of ANGPT1 15 0.45 10.82 2.13 5.00
111 INT3723 Binding of PON1 9 0.46 5.83 2.13 5.00
112 INT664 Positive_regulation of Fgg 14 0.46 8.75 2.11 5.00
113 INT11390 Gene_expression of PF4 5 0.65 3.09 2.07 5.00
114 INT70878 Gene_expression of CYP2A6 17 0.75 4.25 2.02 5.00
115 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88 5.00
116 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7 5.00
117 INT73816 Positive_regulation of Fgf1 5 0.70 2.31 1.49 5.00
118 INT126334 Gene_expression of Tnfrsf10b 8 0.58 8.68 1.42 5.00
119 INT92245 Negative_regulation of Fgg 13 0.06 9.68 1.35 5.00
120 INT10576 Gene_expression of Cyp21a1 7 0.44 1.62 1.32 5.00
121 INT13674 Gene_expression of Cyp1a1 13 0.65 2.22 1.25 5.00
122 INT207134 Positive_regulation of tryptase 11 0.47 11.16 1.21 5.00
123 INT174557 Negative_regulation of Gene_expression of Cd28 7 0.43 4.42 1.2 5.00
124 INT22770 Regulation of Gene_expression of Egf 5 0.44 2.56 1.12 5.00
125 INT116362 Positive_regulation of C4A 17 0.69 11.53 1.03 5.00
126 INT19431 Positive_regulation of Gene_expression of MTRF1 5 0.05 3.13 0.95 5.00
127 INT130671 Regulation of Gene_expression of Cyp1a2 2 0.43 1.27 0.87 5.00
128 INT15870 Regulation of PSS 6 0.25 3.22 0.85 5.00
129 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81 5.00
130 INT180361 Positive_regulation of AMELX 7 0.12 6.03 0.76 5.00
131 INT246524 Binding of QPCT 4 0.05 3.65 0.72 5.00
132 INT87458 Binding of CD81 4 0.18 6.02 0.59 5.00
133 INT174556 Regulation of Gene_expression of Cd28 3 0.42 2.9 0.57 5.00
134 INT254368 Gene_expression of XCR1 1 0.20 1.03 0.55 5.00
135 INT113219 Binding of TNFRSF25 12 0.35 9.77 0.46 5.00
136 INT212995 Positive_regulation of Gene_expression of Vwf 3 0.27 3.01 0.4 5.00
137 INT180353 Binding of AMELX 10 0.04 15.34 0.4 5.00
138 INT42338 Gene_expression of Amhr2 3 0.65 1.02 0.39 5.00
139 INT254367 Transcription of TEK 1 0.14 1.08 0.36 5.00
140 INT254372 Negative_regulation of TEK 1 0.12 1.05 0.31 5.00
141 INT180362 Negative_regulation of AMELX 2 0.11 1.51 0.27 5.00
142 INT52177 Binding of Cyp2d1 2 0.36 0.57 0.26 5.00
143 INT214883 Binding of Atcay 2 0.10 1.1 0.22 5.00
144 INT180352 Regulation of AMELX 1 0.03 4.02 0.21 5.00
145 INT180332 Gene_expression of Sla 6 0.17 9.77 0.16 5.00
146 INT119103 Gene_expression of FIP1L1 2 0.49 2.95 0.11 5.00
147 INT180336 Regulation of Asgr2 1 0.05 1.41 0.08 5.00
148 INT180369 Binding of ENAM 6 0.24 8.53 0.08 5.00
149 INT180339 Localization of Sla 1 0.16 1.34 0.07 5.00
150 INT180333 Positive_regulation of Asgr2 1 0.08 0.82 0.07 5.00
151 INT180371 Positive_regulation of Binding of ENAM 1 0.08 1.97 0.05 5.00
152 INT180335 Positive_regulation of Binding of Uggt1 1 0.17 2.04 0.05 5.00
153 INT180357 Positive_regulation of Binding of AIRE 1 0.08 1.96 0.05 5.00
154 INT180342 Gene_expression of Asgr2 1 0.09 1.46 0.05 5.00
155 INT180328 Binding of Uggt1 1 0.12 2.03 0.05 5.00
156 INT180329 Positive_regulation of Binding of Cyp2d4 1 0.33 1.97 0.05 5.00
157 INT180355 Binding of AIRE 1 0.06 7.13 0.05 5.00
158 INT176561 Gene_expression of Cyp17a1 3 0.25 1.38 0.04 5.00
159 INT180368 Localization of AMELX 1 0.06 1.9 0.03 5.00
160 INT180359 Localization of AIRE 3 0.54 3.94 0.03 5.00
161 INT214882 Gene_expression of Atcay 2 0.17 0.67 0 5.00
162 INT180365 Negative_regulation of Negative_regulation of ENAM 1 0.06 1.67 0 5.00
163 INT180327 Gene_expression of Bcar3 1 0.01 0.66 0 5.00
164 INT180370 Phosphorylation of AMELX 1 0.06 3.05 0 5.00
165 INT249680 Binding of CHCHD2 1 0.01 2.45 0 5.00
166 INT180340 Binding of Asf1a 1 0.01 0.36 0 5.00
167 INT180358 Positive_regulation of Localization of AIRE 1 0.07 1.17 0 5.00
168 INT180337 Gene_expression of Cyp2b3 1 0.27 0.32 0 5.00
169 INT180330 Positive_regulation of Amhr2 1 0.01 0.57 0 5.00
170 INT180341 Regulation of Ftcd 1 0.01 2.06 0 5.00
171 INT180354 Negative_regulation of ENAM 1 0.06 1.64 0 5.00
172 INT180360 Gene_expression of ENAM 2 0.45 3.58 0 5.00
173 INT180364 Gene_expression of TRNP 1 0.03 1.1 0 5.00
174 INT180334 Gene_expression of Asf1a 1 0.01 1.29 0 5.00
175 INT180356 Binding of SEPSECS 1 0.02 0.71 0 5.00
176 INT180326 Regulation of Gene_expression of Cyp2d4 1 0.18 0.77 0 5.00
177 INT180367 Positive_regulation of ENAM 1 0.07 1.67 0 5.00
178 INT180331 Regulation of Sla 1 0.06 1.44 0 5.00
179 INT180325 Regulation of Secp43 1 0.01 1.6 0 5.00
180 INT180363 Positive_regulation of AIRE 1 0.10 1.18 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox