D:Takayasu Arteritis

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pChart

Disease Term
Synonyms Aortitis Syndrome, Arteritis Takayasu, Arteritis Takayasu S, Arteritis Takayasus, Pulseless Disease, Syndrome Aortitis, TAKAYASU S ARTERITIS, Takayasu Syndrome, Takayasus Arteritis
Documents 134
Hot Single Events 31
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Takayasu Arteritis. They are ordered first by their relevance to Takayasu Arteritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT346971 Binding of IL4 and IL10 1 0.12 0.16 0 86.24
2 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14 33.28
3 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58 5.00
4 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Takayasu Arteritis. They are ordered first by their pain relevance and then by number of times they were reported in Takayasu Arteritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT114031 Gene_expression of ORM1 3 0.41 6.31 1.18 99.98
2 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91 99.64
3 INT346983 Negative_regulation of ISG15 1 0.19 3.69 0.35 99.64
4 INT140637 Negative_regulation of IFI27 11 0.40 9.48 0.69 99.64
5 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.56
6 INT101739 Gene_expression of CACNA1E 2 0.25 0.43 0.49 99.52
7 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.32
8 INT190337 Negative_regulation of IFI44 2 0.23 2.02 0.18 99.24
9 INT346978 Negative_regulation of IFIT1 1 0.13 1.83 0.17 99.24
10 INT346980 Negative_regulation of IFIT2 1 0.13 1.83 0.17 99.24
11 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 98.88
12 INT315684 Gene_expression of DEFA3 2 0.54 1.46 0 98.32
13 INT339173 Regulation of AREG 2 0.26 1.83 0.2 96.68
14 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 93.64
15 INT264435 Positive_regulation of Gene_expression of IL1R2 2 0.10 2.46 0.69 93.56
16 INT346981 Positive_regulation of Gene_expression of CXCR1 1 0.05 1.18 0.22 93.56
17 INT79883 Positive_regulation of SRSF6 1 0.49 1.12 0.19 93.48
18 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 93.48
19 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69 93.48
20 INT146971 Gene_expression of IL1R2 3 0.67 2.69 0.69 93.20
21 INT66606 Gene_expression of CXCR1 34 0.75 27.79 11.36 93.20
22 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 91.80
23 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 90.08
24 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 89.12
25 INT162531 Binding of Eln 4 0.43 3.8 0.42 87.80
26 INT77146 Binding of IL4 23 0.36 13.69 5.39 86.24
27 INT142162 Binding of IL10 30 0.37 21.9 4.84 86.24
28 INT928 Positive_regulation of Aebp1 2 0.35 1.53 0.8 86.20
29 INT337670 Positive_regulation of DEFA3 7 0.42 10.51 0 82.16
30 INT346982 Positive_regulation of Gene_expression of ORM1 1 0.06 0.2 0 82.16
31 INT337660 Positive_regulation of Positive_regulation of DEFA3 4 0.42 5.4 0 82.16
32 INT39948 Binding of FLNA 45 0.42 58.05 4.27 72.28
33 INT71782 Gene_expression of MAP2K1 7 0.68 3.17 1.37 52.60
34 INT22502 Gene_expression of Hal 21 0.53 9.8 3.32 50.00
35 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 46.52
36 INT346979 Transcription of ORM1 1 0.06 0 0 29.20
37 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
38 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
39 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
40 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
41 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
42 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
43 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
44 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
45 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
46 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
47 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 5.00
48 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 5.00
49 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
50 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 5.00
51 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 5.00
52 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 5.00
53 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
54 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 5.00
55 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 5.00
56 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 5.00
57 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36 5.00
58 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 5.00
59 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 5.00
60 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 5.00
61 INT18872 Negative_regulation of Asap1 18 0.43 8.48 5.42 5.00
62 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 5.00
63 INT6476 Gene_expression of TNFRSF1B 21 0.67 18.22 5.25 5.00
64 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 5.00
65 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81 5.00
66 INT174195 Negative_regulation of HLA-E 31 0.42 11.98 3.88 5.00
67 INT11261 Positive_regulation of PTPLA 3 0.50 4.4 3.74 5.00
68 INT47949 Positive_regulation of ELOVL1 19 0.42 29.78 3.3 5.00
69 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77 5.00
70 INT46646 Localization of FLNA 19 0.73 18.83 2.53 5.00
71 INT8512 Gene_expression of PREP 17 0.65 7.98 2.5 5.00
72 INT56221 Regulation of MPO 8 0.61 8.44 1.84 5.00
73 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58 5.00
74 INT20633 Positive_regulation of Gene_expression of LDHA 15 0.49 15.94 1.42 5.00
75 INT47950 Negative_regulation of ELOVL1 15 0.41 20.33 1.41 5.00
76 INT22235 Gene_expression of Eln 11 0.76 5.4 1.23 5.00
77 INT169363 Negative_regulation of PTGIS 4 0.20 3.35 1.22 5.00
78 INT274219 Positive_regulation of Gene_expression of Eln 4 0.06 2.69 0.22 5.00
79 INT274220 Negative_regulation of Gene_expression of Eln 1 0.05 2.6 0.13 5.00
80 INT197053 Negative_regulation of Binding of HLA-E 1 0.20 1.07 0.12 5.00
81 INT193358 Localization of ST3GAL4 2 0.52 1.65 0.05 5.00
82 INT274221 Regulation of Gene_expression of Eln 1 0.04 0.82 0.04 5.00
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