D:Taste Disorders

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Disease Term
Synonyms Metallic Taste, Metallic Tastes, Primary Taste Disorder, Primary Taste Disorders, Secondary Taste Disorder, Secondary Taste Disorders, TASTE DISORDER, Taste Disorder Anterior Tongue, Taste Disorder Posterior Tongue, Taste Disorder Primary, Taste Disorder Primary Bitter
Documents 79
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Taste Disorders. They are ordered first by their relevance to Taste Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT116892 Binding of TRPV1 and Phax 4 0.00 0.1 1.24 5.00
2 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97 5.00
3 INT245920 Binding of GLA and TRPV1 1 0.09 0.36 0.26 5.00
4 INT245926 Binding of ABCC1 and TRPV1 1 0.17 0.36 0.26 5.00
5 INT199595 FGF7 Positive_regulation of Transcription of TNF 1 0.40 0.58 0.11 5.00
6 INT245918 MRPS7 Negative_regulation of TRPV1 1 0.41 0.06 0.1 5.00
7 INT245952 Phax Negative_regulation of TRPV1 1 0.00 0.06 0.1 5.00
8 INT245927 CAP1 Negative_regulation of TRPV1 1 0.02 0.06 0.1 5.00
9 INT164925 GIP Positive_regulation of Localization of INS 2 0.59 0.86 0.09 5.00
10 INT245951 Binding of FIBP and Phax 1 0.00 0 0.09 5.00
11 INT245921 Binding of FIBP and CAP1 1 0.00 0 0.09 5.00
12 INT199594 FGF7 Positive_regulation of NFE2L2 1 0.01 0.52 0.09 5.00
13 INT199604 Binding of FGF7 and Fgf1 1 0.03 0.21 0.08 5.00
14 INT199603 Positive_regulation of Binding of FGF7 and Fgf1 1 0.04 0.21 0.08 5.00
15 INT245919 Binding of TRPV1 and MRPS7 1 0.47 0 0.06 5.00
16 INT245922 Binding of GLA and FIBP 1 0.00 0 0.03 5.00
17 INT245917 Binding of GLA and ABCC1 1 0.05 0 0.03 5.00
18 INT245923 Binding of ABCC1 and FIBP 1 0.00 0 0.03 5.00
19 INT245925 GLA Regulation of TRPV1 1 0.07 0 0 5.00
20 INT255024 DPP4 Negative_regulation of Protein_catabolism of GLP1R 1 0.14 0.78 0 5.00
21 INT245924 ABCC1 Regulation of TRPV1 1 0.11 0 0 5.00
22 INT303469 CDH3 Negative_regulation of Dpyd 1 0.01 0 0 5.00
23 INT255021 DPP4 Negative_regulation of Protein_catabolism of GIP 1 0.32 0.78 0 5.00
24 INT255025 Positive_regulation of GLP1R Positive_regulation of Localization of INS 1 0.17 0.12 0 5.00
25 INT255023 Negative_regulation of DPP4 Positive_regulation of GIP 1 0.35 0.27 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Taste Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Taste Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 99.78
2 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 98.56
3 INT166105 Binding of ptd 1 0.32 0.95 0.12 97.90
4 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 95.28
5 INT28985 Regulation of epi 5 0.44 0.81 1.67 94.92
6 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 91.04
7 INT158269 Gene_expression of Trpm5 18 0.76 2.06 1.2 90.24
8 INT172664 Gene_expression of ZBTB22 2 0.58 0.22 0.22 89.04
9 INT166106 Localization of ptd 1 0.60 0.94 0.14 88.88
10 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19 81.60
11 INT18088 Binding of Tspo 26 0.48 9.12 10.2 77.60
12 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 77.12
13 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67 75.20
14 INT5401 Gene_expression of DBH 17 0.78 1.92 8.01 75.20
15 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 75.20
16 INT61449 Gene_expression of NPFF 9 0.78 2.67 6.5 75.20
17 INT96234 Localization of Il13 11 0.62 10.94 5.48 75.12
18 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 72.72
19 INT62441 Gene_expression of ABCC1 56 0.78 21.01 12.93 71.92
20 INT78913 Positive_regulation of Gene_expression of ABCC1 22 0.67 5.95 5.82 71.92
21 INT158270 Negative_regulation of Trpm5 10 0.57 2.49 0.52 66.24
22 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 65.36
23 INT154303 Negative_regulation of DCPS 27 0.36 33.83 5.45 61.28
24 INT135729 Gene_expression of Zap70 5 0.75 6.86 0.75 59.00
25 INT135731 Gene_expression of NAE1 4 0.29 5.05 0.3 45.56
26 INT114446 Gene_expression of CAMK2D 2 0.01 0.59 0.36 40.28
27 INT23994 Positive_regulation of epi 5 0.64 1.65 2.15 29.36
28 INT172307 Binding of TAS2R14 3 0.37 2.66 0.58 21.32
29 INT284058 Negative_regulation of Vsnl1 2 0.21 1.95 0.09 20.96
30 INT39415 Gene_expression of HBN1 33 0.43 19.31 0.93 16.64
31 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 11.80
32 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
33 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
34 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
35 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
36 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 5.00
37 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
38 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
39 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 5.00
40 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 5.00
41 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
42 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 5.00
43 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
44 INT19488 Localization of ABAT 56 0.69 21.51 50.56 5.00
45 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
46 INT13354 Transcription of TNF 108 0.72 85.81 42.32 5.00
47 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
48 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
49 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 5.00
50 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 5.00
51 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
52 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 5.00
53 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
54 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
55 INT22066 Gene_expression of Phax 40 0.78 22.51 25.91 5.00
56 INT17625 Localization of GCG 210 0.80 55.69 24.97 5.00
57 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
58 INT101501 Phosphorylation of TRPV1 31 0.82 9.26 17.27 5.00
59 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87 5.00
60 INT81087 Gene_expression of ASIC3 30 0.75 13.62 16.54 5.00
61 INT81088 Gene_expression of ASIC1 26 0.77 17.8 15.07 5.00
62 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
63 INT64225 Positive_regulation of Localization of ABAT 15 0.60 4.46 11.28 5.00
64 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
65 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
66 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94 5.00
67 INT4494 Regulation of GCG 41 0.45 18.38 9.68 5.00
68 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
69 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 5.00
70 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48 5.00
71 INT92777 Positive_regulation of Gene_expression of ABAT 13 0.44 7.49 9.27 5.00
72 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
73 INT93310 Gene_expression of CAP1 14 0.58 3.07 8.55 5.00
74 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35 5.00
75 INT156827 Localization of MRI1 25 0.65 16.06 8.33 5.00
76 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 5.00
77 INT159632 Localization of DCPS 24 0.21 18.24 6.8 5.00
78 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 5.00
79 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88 5.00
80 INT52904 Positive_regulation of LTF 21 0.67 15.58 5.78 5.00
81 INT31227 Regulation of Localization of GCG 28 0.48 4.86 5.72 5.00
82 INT177584 Gene_expression of MR1 80 0.58 46.48 5.48 5.00
83 INT78914 Positive_regulation of ABCC1 19 0.67 7.99 5.18 5.00
84 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 5.00
85 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26 5.00
86 INT144 Positive_regulation of H1 10 0.64 2.77 4.13 5.00
87 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83 5.00
88 INT81089 Positive_regulation of ASIC1 14 0.65 4.42 3.82 5.00
89 INT143494 Binding of DCPS 24 0.29 24.41 3.67 5.00
90 INT158843 Regulation of NALCN 6 0.04 2.89 3.63 5.00
91 INT84473 Gene_expression of SARDH 5 0.77 1.21 3.37 5.00
92 INT16236 Negative_regulation of CFH 31 0.57 19.59 3.36 5.00
93 INT66191 Gene_expression of DBP 42 0.66 22.25 3.18 5.00
94 INT101368 Positive_regulation of Gene_expression of ASIC3 6 0.32 2.61 3.06 5.00
95 INT109061 Gene_expression of PRKD1 5 0.58 1.8 3.04 5.00
96 INT93198 Transcription of ASIC1 7 0.62 1.96 3.04 5.00
97 INT120490 Regulation of Regulation of TRPV1 4 0.45 2.36 3.02 5.00
98 INT177586 Positive_regulation of Gene_expression of MRI1 9 0.33 4.97 2.91 5.00
99 INT74983 Transcription of NA 9 0.41 1.71 2.79 5.00
100 INT83374 Gene_expression of FGF7 83 0.78 44.18 2.6 5.00
101 INT39518 Negative_regulation of HBN1 66 0.09 37.54 2.58 5.00
102 INT1829 Gene_expression of CFH 71 0.75 64.24 2.49 5.00
103 INT87360 Binding of ABCC1 6 0.47 1.71 2.38 5.00
104 INT84465 Localization of DPP4 8 0.75 7.28 2.29 5.00
105 INT93009 Regulation of HBN1 24 0.17 17.6 2.03 5.00
106 INT173851 Localization of FN1 20 0.76 13.95 1.97 5.00
107 INT245945 Localization of CAP1 4 0.69 1.63 1.95 5.00
108 INT198568 Regulation of DCPS 17 0.34 16.26 1.86 5.00
109 INT166819 Gene_expression of IMPA1 12 0.65 3.85 1.77 5.00
110 INT77415 Localization of GLP1R 23 0.63 11.1 1.69 5.00
111 INT19214 Gene_expression of Msg 3 0.51 0.79 1.52 5.00
112 INT114080 Negative_regulation of Negative_regulation of ABAT 3 0.38 1.53 1.47 5.00
113 INT199601 Positive_regulation of FGF7 9 0.50 6.13 1.22 5.00
114 INT145960 Positive_regulation of GLP1R 19 0.58 7.25 1.19 5.00
115 INT162064 Gene_expression of PKD2L1 12 0.63 2.71 1.1 5.00
116 INT91106 Negative_regulation of LTF 9 0.51 5.73 1.09 5.00
117 INT166818 Positive_regulation of Gene_expression of IMPA1 3 0.36 0.99 1.06 5.00
118 INT29372 Localization of GIP 18 0.69 7.23 1.01 5.00
119 INT177587 Regulation of Gene_expression of MRI1 4 0.22 0.88 0.97 5.00
120 INT19084 Negative_regulation of NRG1 5 0.42 4.9 0.96 5.00
121 INT199598 Binding of FGF7 4 0.48 2.83 0.9 5.00
122 INT29455 Regulation of Msg 2 0.22 0.12 0.87 5.00
123 INT84462 Positive_regulation of Localization of DPP4 2 0.32 1.27 0.85 5.00
124 INT57560 Positive_regulation of GLA 14 0.54 5.01 0.83 5.00
125 INT70744 Regulation of CFH 12 0.41 7.38 0.8 5.00
126 INT93908 Negative_regulation of Dpyd 9 0.45 3.19 0.78 5.00
127 INT233921 Binding of PDR 6 0.14 7.03 0.75 5.00
128 INT245941 Regulation of ABCC1 3 0.26 1.61 0.69 5.00
129 INT164258 Positive_regulation of Gene_expression of GLA 6 0.47 0.55 0.65 5.00
130 INT211008 Transcription of PKD1L3 2 0.60 0 0.61 5.00
131 INT145957 Positive_regulation of Localization of GLP1R 5 0.43 2.12 0.61 5.00
132 INT212293 Gene_expression of Vsnl1 14 0.29 8.1 0.61 5.00
133 INT212292 Binding of Vsnl1 2 0.18 5.18 0.61 5.00
134 INT283141 Transcription of PKD2L1 1 0.65 0 0.58 5.00
135 INT283142 Gene_expression of PKD1L3 1 0.59 0 0.58 5.00
136 INT124042 Localization of FGF7 10 0.80 4.13 0.57 5.00
137 INT218223 Gene_expression of TAS1R3 2 0.58 0.34 0.56 5.00
138 INT245929 Positive_regulation of Msg 1 0.05 0.38 0.56 5.00
139 INT199602 Positive_regulation of Gene_expression of FGF7 12 0.70 7.47 0.55 5.00
140 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53 5.00
141 INT602 Positive_regulation of TAS1R3 2 0.25 0.5 0.52 5.00
142 INT245930 Regulation of Gene_expression of Msg 1 0.04 0.22 0.47 5.00
143 INT148882 Regulation of LTF 9 0.12 4.8 0.44 5.00
144 INT145928 Negative_regulation of SERPINA4 5 0.07 2.05 0.43 5.00
145 INT245928 Regulation of Regulation of Msg 1 0.04 0.12 0.42 5.00
146 INT284059 Positive_regulation of Vsnl1 4 0.22 5.18 0.38 5.00
147 INT245944 Binding of MRPS7 1 0.47 0.06 0.31 5.00
148 INT283147 Gene_expression of SCNN1B 1 0.09 0.26 0.3 5.00
149 INT283143 Binding of PKD2L1 1 0.35 0 0.28 5.00
150 INT242211 Negative_regulation of GLP1R 9 0.36 3.4 0.26 5.00
151 INT92990 Binding of Mthfr 2 0.37 2.42 0.25 5.00
152 INT245946 Regulation of Regulation of MRPS7 1 0.44 0.06 0.24 5.00
153 INT245947 Regulation of MRPS7 1 0.44 0.06 0.24 5.00
154 INT245931 Regulation of Positive_regulation of Msg 1 0.04 0.36 0.24 5.00
155 INT117050 Binding of GLA 8 0.47 2.41 0.22 5.00
156 INT199599 Negative_regulation of Gene_expression of FGF7 3 0.48 0.78 0.19 5.00
157 INT213275 Positive_regulation of Gene_expression of SHBG 6 0.46 4.24 0.19 5.00
158 INT283146 Positive_regulation of TAS2R14 2 0.50 0.64 0.18 5.00
159 INT245948 Regulation of TAS1R3 1 0.14 0.13 0.17 5.00
160 INT199600 Negative_regulation of Localization of FGF7 1 0.35 1.09 0.16 5.00
161 INT39917 Negative_regulation of GIP 3 0.46 1.08 0.15 5.00
162 INT255030 Protein_catabolism of GLP1R 5 0.84 2.39 0.14 5.00
163 INT57561 Regulation of Gene_expression of GLA 2 0.60 0.49 0.13 5.00
164 INT346054 Positive_regulation of Gene_expression of Vsnl1 1 0.22 1.13 0.11 5.00
165 INT177588 Localization of SARDH 2 0.18 0.46 0.09 5.00
166 INT223375 Localization of TSPAN31 3 0.73 1.3 0.09 5.00
167 INT177585 Positive_regulation of Gene_expression of SARDH 1 0.12 0 0.09 5.00
168 INT346055 Negative_regulation of Gene_expression of Vsnl1 1 0.18 0.99 0.06 5.00
169 INT255032 Negative_regulation of Localization of DPP4 1 0.30 0.24 0.04 5.00
170 INT255034 Positive_regulation of Negative_regulation of DPP4 2 0.37 0.83 0.03 5.00
171 INT245942 Regulation of Positive_regulation of ABCC1 1 0.18 0.4 0.03 5.00
172 INT303110 Positive_regulation of Positive_regulation of LTF 1 0.04 0.45 0.03 5.00
173 INT283144 Binding of PKD1L3 1 0.31 0 0.03 5.00
174 INT245940 Regulation of Positive_regulation of GLA 1 0.11 0.4 0.03 5.00
175 INT255035 Gene_expression of SCAND1 1 0.05 0.24 0 5.00
176 INT340485 Positive_regulation of Map2k1ip1 1 0.38 0.12 0 5.00
177 INT80782 Positive_regulation of PSD 5 0.18 0.72 0 5.00
178 INT245943 Binding of ZBTB22 1 0.04 0 0 5.00
179 INT303111 Negative_regulation of Positive_regulation of LTF 1 0.03 0.13 0 5.00
180 INT340487 Localization of Map2k1ip1 1 0.50 0 0 5.00
181 INT340486 Gene_expression of Map2k1ip1 1 0.51 0 0 5.00
182 INT303113 Negative_regulation of Positive_regulation of PSD 1 0.03 0.58 0 5.00
183 INT255031 Protein_catabolism of GIP 1 0.83 0.32 0 5.00
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