D:Thrombocytopenic Purpura

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pChart

Disease Term
Synonyms PURPURA THROMBOCYTOPENIC, Purpura Thrombopenic, Purpuras Thrombocytopenic, PURPURAS THROMBOPENIC, Thrombocytopaenia Purpura, Thrombocytopaenic Purpura, Thrombocytopaenic Purpura Disorder, Thrombocytopenia Purpura, Thrombocytopenic Purpura Disorder, Thrombocytopenic Purpuras, Thrombopenic Purpura
Documents 23
Hot Single Events 4
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Thrombocytopenic Purpura. They are ordered first by their relevance to Thrombocytopenic Purpura and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT61915 Binding of Fcgr1 and Slc3a2 1 0.02 0.43 0.06 95.32
2 INT61916 Binding of Fcgr1 and IgG2a 1 0.47 0.93 0.12 93.96
3 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14 5.00
4 INT232015 SERPING1 Negative_regulation of F12 2 0.24 1.19 0.12 5.00
5 INT232017 F12 Positive_regulation of PLG 1 0.03 0.52 0.11 5.00
6 INT232010 PLG Positive_regulation of TRGC1 1 0.08 0.51 0.09 5.00
7 INT232019 F12 Positive_regulation of TRGC1 1 0.00 0.57 0.09 5.00
8 INT232011 SERPING1 Regulation of Negative_regulation of SERPINE1 1 0.01 0.45 0.07 5.00
9 INT232009 Positive_regulation of F12 Negative_regulation of Localization of KNG1 1 0.01 0.19 0.05 5.00
10 INT232012 SERPING1 Negative_regulation of C1R 1 0.18 0.72 0.04 5.00
11 INT232013 SERPING1 Negative_regulation of C1S 1 0.24 0.72 0.04 5.00
12 INT232016 SERPING1 Regulation of C1S 1 0.15 0.57 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Thrombocytopenic Purpura. They are ordered first by their pain relevance and then by number of times they were reported in Thrombocytopenic Purpura. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 95.12
2 INT61913 Binding of IgG2a 10 0.47 5.04 1.64 93.96
3 INT11488 Negative_regulation of KLK1 15 0.57 9.92 3.06 82.00
4 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 81.56
5 INT61910 Binding of Slc3a2 6 0.01 3 0.7 75.00
6 INT61912 Gene_expression of Fcgr1 3 0.69 1.13 0.41 75.00
7 INT61911 Negative_regulation of Gene_expression of Fcgr1 1 0.38 0.39 0.07 75.00
8 INT48141 Binding of Csf3 18 0.39 9.93 1.71 67.28
9 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 52.88
10 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 48.92
11 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75 33.92
12 INT7134 Localization of KNG1 127 0.79 65.73 67.97 5.00
13 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 5.00
14 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 5.00
15 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
16 INT3076 Regulation of KNG1 52 0.60 20.39 27.89 5.00
17 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 5.00
18 INT3167 Binding of KNG1 48 0.48 23.26 26.77 5.00
19 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
20 INT3364 Binding of SGCG 87 0.47 31.93 17.24 5.00
21 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 5.00
22 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68 5.00
23 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17 5.00
24 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5 5.00
25 INT11493 Positive_regulation of KLK1 21 0.67 9.22 5 5.00
26 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 5.00
27 INT10136 Negative_regulation of PLAT 23 0.42 11.18 3.02 5.00
28 INT134077 Phosphorylation of Vasp 24 0.80 8.38 2.96 5.00
29 INT156130 Binding of SERPING1 29 0.42 26.16 2.52 5.00
30 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14 5.00
31 INT78429 Positive_regulation of TRGC1 11 0.44 4.6 2.1 5.00
32 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98 5.00
33 INT88375 Negative_regulation of Localization of KNG1 4 0.39 1.12 1.91 5.00
34 INT11481 Positive_regulation of F12 11 0.58 5.53 1.8 5.00
35 INT14205 Regulation of KLK1 10 0.60 4.38 1.28 5.00
36 INT156672 Localization of SERPING1 10 0.74 12.15 1.25 5.00
37 INT41893 Negative_regulation of HBS1L 16 0.23 8.98 1.19 5.00
38 INT111681 Regulation of P2ry1 8 0.45 2.64 1.11 5.00
39 INT128609 Gene_expression of C1S 18 0.75 17.36 0.98 5.00
40 INT35141 Regulation of PLG 6 0.44 2.64 0.85 5.00
41 INT234954 Negative_regulation of DSG1 22 0.42 19.5 0.62 5.00
42 INT102578 Gene_expression of HBE1 22 0.47 10.39 0.6 5.00
43 INT145530 Negative_regulation of Positive_regulation of KLK1 2 0.42 1.02 0.57 5.00
44 INT88688 Negative_regulation of HBE1 33 0.26 18.46 0.5 5.00
45 INT221932 Gene_expression of F12 4 0.66 2.61 0.5 5.00
46 INT134074 Negative_regulation of Vasp 2 0.42 0.6 0.42 5.00
47 INT184641 Regulation of TRGC1 4 0.40 2.84 0.34 5.00
48 INT232021 Positive_regulation of Gene_expression of SERPING1 8 0.49 4.99 0.31 5.00
49 INT174519 Gene_expression of C1R 4 0.35 0.51 0.29 5.00
50 INT26453 Binding of KLK1 2 0.47 0.84 0.28 5.00
51 INT232024 Protein_catabolism of KLK1 2 0.64 1.21 0.28 5.00
52 INT228644 Positive_regulation of Negative_regulation of SERPING1 5 0.46 4.21 0.21 5.00
53 INT58589 Regulation of F12 3 0.39 1.9 0.16 5.00
54 INT232025 Regulation of Gene_expression of SERPING1 3 0.56 1.75 0.15 5.00
55 INT232026 Positive_regulation of Gene_expression of F12 1 0.03 0.58 0.11 5.00
56 INT268000 Positive_regulation of Vasp 1 0.10 0.31 0.11 5.00
57 INT232027 Positive_regulation of Positive_regulation of SERPING1 2 0.46 1.48 0.08 5.00
58 INT232022 Positive_regulation of Gene_expression of C1R 1 0.20 0.16 0.07 5.00
59 INT232023 Positive_regulation of Gene_expression of C1S 1 0.27 0.16 0.07 5.00
60 INT268002 Positive_regulation of TIMELESS 1 0.67 0.31 0 5.00
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