D:Thrombocytosis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms ELEVATED PLATELET COUNT, INCREASED PLATELETS, Platelet Count Increased, PLATELETS ELEVATED, Thrombocyte Count Increased, Thrombocythaemia, Thrombocythemia, Thrombocythemias, THROMBOCYTOSES
Documents 77
Hot Single Events 29
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Thrombocytosis. They are ordered first by their relevance to Thrombocytosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT106486 Gene_expression of CD177 Negative_regulation of Gene_expression of Bcl2l1 1 0.01 1.87 0.04 93.76
2 INT106487 Gene_expression of CD177 Negative_regulation of Gene_expression of Mpl 1 0.02 1.74 0.04 89.36
3 INT177899 Crp Positive_regulation of Positive_regulation of Crp 1 0.01 1.69 0.6 5.00
4 INT177901 Binding of IL6 and Wbc1 1 0.00 1.05 0.31 5.00
5 INT177897 Binding of Il1 and Wbc1 1 0.00 0.74 0.25 5.00
6 INT177895 Binding of Crp and Wbc1 1 0.00 0.45 0.22 5.00
7 INT177898 Binding of Crp and Wbc1 1 0.00 0.49 0.09 5.00
8 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0 5.00
9 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0 5.00
10 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Thrombocytosis. They are ordered first by their pain relevance and then by number of times they were reported in Thrombocytosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 99.82
2 INT57424 Positive_regulation of TNNT1 42 0.67 31.84 9.7 99.70
3 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 99.40
4 INT106483 Negative_regulation of Gene_expression of Mpl 6 0.43 5.87 0.27 99.08
5 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 98.92
6 INT106484 Gene_expression of Mpl 7 0.78 20.2 16.48 98.60
7 INT11071 Positive_regulation of PPBP 43 0.68 26.85 13.43 98.24
8 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96 98.24
9 INT19941 Negative_regulation of Pf4 13 0.42 10.35 5.97 96.68
10 INT16460 Negative_regulation of PPBP 21 0.57 13.86 8.54 96.68
11 INT19107 Positive_regulation of Tbxa2r 23 0.62 12.54 8.44 96.16
12 INT14962 Gene_expression of Pf4 27 0.76 22.48 10.88 96.14
13 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52 96.14
14 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 93.76
15 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28 93.76
16 INT11897 Gene_expression of Atp7b 25 0.13 7.85 12.5 93.20
17 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 92.96
18 INT60685 Positive_regulation of Gene_expression of Epo 21 0.53 15.86 1.25 92.96
19 INT106482 Negative_regulation of Gene_expression of Epo 3 0.07 10.96 0.31 89.36
20 INT94934 Negative_regulation of COX1 3 0.57 3.27 1.75 88.40
21 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 88.40
22 INT97157 Gene_expression of CD177 7 0.75 5.14 1.35 87.04
23 INT106485 Positive_regulation of Gene_expression of CD177 1 0.14 1.72 0.03 87.04
24 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 85.16
25 INT25283 Negative_regulation of Positive_regulation of Vwf 2 0.21 2.7 0.69 85.16
26 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 84.80
27 INT30209 Localization of SCN5A 24 0.72 7.95 5.35 83.68
28 INT36703 Negative_regulation of CEACAM3 2 0.43 4.11 0.53 83.24
29 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81 80.24
30 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 74.76
31 INT83646 Binding of Il1rn 12 0.37 4.41 3.51 73.12
32 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 70.48
33 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41 68.64
34 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16 56.40
35 INT38362 Positive_regulation of Wbc1 19 0.06 13.24 2.95 38.72
36 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 27.96
37 INT55114 Gene_expression of CRS 42 0.58 26.86 4.69 27.36
38 INT177896 Binding of Wbc1 1 0.01 6.06 1.7 7.72
39 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
40 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
41 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
42 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
43 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
44 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
45 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
46 INT22454 Regulation of Crp 213 0.62 160.67 49.24 5.00
47 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
48 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
49 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
50 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
51 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
52 INT25607 Binding of Il1 82 0.47 64.4 23.9 5.00
53 INT20129 Regulation of Il1 53 0.53 44.14 19.89 5.00
54 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 5.00
55 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 5.00
56 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 5.00
57 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 5.00
58 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 5.00
59 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21 5.00
60 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82 5.00
61 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
62 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 5.00
63 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 5.00
64 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
65 INT37390 Regulation of Crp 39 0.46 28.74 11.45 5.00
66 INT18412 Binding of PLEK 49 0.47 17.82 10.72 5.00
67 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 5.00
68 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 5.00
69 INT10969 Positive_regulation of PLEK 33 0.67 16.96 8.35 5.00
70 INT63401 Gene_expression of Il5 33 0.72 18.66 8.2 5.00
71 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
72 INT17996 Binding of Crp 40 0.37 31.4 7.8 5.00
73 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 5.00
74 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36 5.00
75 INT126481 Gene_expression of Cxcr4 69 0.77 34.99 6 5.00
76 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 5.00
77 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23 5.00
78 INT102547 Gene_expression of Cd68 25 0.75 14.47 5.22 5.00
79 INT153189 Gene_expression of Sema3a 19 0.75 14.37 4.21 5.00
80 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37 5.00
81 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
82 INT4873 Positive_regulation of FCGR3A 21 0.49 14.35 2.89 5.00
83 INT31450 Binding of HIST1H1B 20 0.37 10.21 2.84 5.00
84 INT98686 Gene_expression of Calb2 28 0.51 12.07 2.84 5.00
85 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83 5.00
86 INT188255 Gene_expression of DKK1 19 0.60 12.69 2.39 5.00
87 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36 5.00
88 INT83236 Localization of PGR 14 0.73 8.26 2.23 5.00
89 INT133648 Regulation of HDAC9 14 0.60 10.01 2.18 5.00
90 INT191154 Binding of HDAC9 20 0.36 14.12 1.83 5.00
91 INT139475 Negative_regulation of DKK1 14 0.52 9.2 1.76 5.00
92 INT33393 Positive_regulation of Gene_expression of PLEK 9 0.67 7.35 1.65 5.00
93 INT133904 Positive_regulation of Ncam1 7 0.50 4.01 1.57 5.00
94 INT76477 Positive_regulation of CD99 14 0.50 14.77 1.42 5.00
95 INT85402 Transcription of Calb2 4 0.61 2.73 1.17 5.00
96 INT133898 Binding of HSP90AA1 17 0.30 8.83 1.12 5.00
97 INT59010 Positive_regulation of Regulation of Crp 2 0.27 2.11 1.09 5.00
98 INT95028 Gene_expression of Chrm4 8 0.39 2.66 0.99 5.00
99 INT23359 Negative_regulation of PF4 6 0.58 3.54 0.97 5.00
100 INT200738 Gene_expression of HIST2H4A 7 0.18 4.65 0.91 5.00
101 INT252313 Positive_regulation of Cd47 4 0.22 3.95 0.87 5.00
102 INT28096 Regulation of Wbc1 4 0.06 2.79 0.82 5.00
103 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82 5.00
104 INT161471 Gene_expression of Bmi1 9 0.76 11.47 0.72 5.00
105 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7 5.00
106 INT185258 Gene_expression of Pou5f1 33 0.60 11.28 0.7 5.00
107 INT190229 Gene_expression of Cd55 7 0.64 5 0.64 5.00
108 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61 5.00
109 INT64977 Gene_expression of TFF3 9 0.75 3.54 0.39 5.00
110 INT207105 Positive_regulation of Cd63 2 0.57 1.82 0.39 5.00
111 INT297626 Gene_expression of RLN3 3 0.11 5.07 0.3 5.00
112 INT256540 Regulation of Gene_expression of TSC1 4 0.07 4.74 0.3 5.00
113 INT265661 Positive_regulation of Gene_expression of HIST2H4A 2 0.09 2.69 0.28 5.00
114 INT190665 Gene_expression of Mixl1 4 0.35 2.54 0.2 5.00
115 INT122740 Positive_regulation of Cd55 4 0.58 2.68 0.18 5.00
116 INT120615 Negative_regulation of TFF3 2 0.42 1.5 0.13 5.00
117 INT159505 Gene_expression of Tnfrsf8 2 0.12 1.35 0.11 5.00
118 INT304939 Gene_expression of Pdgfd 1 0.35 2.71 0.1 5.00
119 INT304933 Gene_expression of Ncam2 1 0.27 1.13 0.1 5.00
120 INT154423 Regulation of CDAN1 2 0.60 1.55 0.09 5.00
121 INT297627 Positive_regulation of Gene_expression of RLN3 3 0.08 3.06 0.08 5.00
122 INT304934 Gene_expression of Abca6 1 0.29 0.56 0.05 5.00
123 INT304935 Transcription of Bmi1 1 0.08 0.65 0.05 5.00
124 INT304940 Positive_regulation of Gene_expression of Pdgfd 1 0.23 0.56 0.05 5.00
125 INT304937 Transcription of Wnt1 1 0.22 0.65 0.05 5.00
126 INT145370 Transcription of DKK1 3 0.53 1.07 0.05 5.00
127 INT284979 Binding of HIST2H4A 2 0.05 2 0.04 5.00
128 INT201549 Regulation of CD99 3 0.23 3.6 0.03 5.00
129 INT275245 Positive_regulation of HIST2H2BE 2 0.15 1.94 0 5.00
130 INT297621 Positive_regulation of RLN3 1 0.05 2.79 0 5.00
131 INT304936 Negative_regulation of Cd46 1 0.28 1.04 0 5.00
132 INT274683 Localization of HIST2H4A 5 0.12 1.54 0 5.00
133 INT297623 Localization of HDAC11 1 0.29 0.26 0 5.00
134 INT297619 Binding of RLN3 1 0.02 1.4 0 5.00
135 INT276530 Negative_regulation of Wt1 5 0.53 2.97 0 5.00
136 INT297620 Negative_regulation of Positive_regulation of RLN3 1 0.03 1.04 0 5.00
137 INT202420 Transcription of Jak2 1 0.56 0.91 0 5.00
138 INT297625 Positive_regulation of Binding of RLN3 1 0.03 1.42 0 5.00
139 INT304938 Positive_regulation of Cd46 1 0.23 0.86 0 5.00
140 INT297628 Negative_regulation of ZNF275 1 0.00 3.2 0 5.00
141 INT297622 Positive_regulation of Binding of HIST2H4A 1 0.06 1.42 0 5.00
142 INT297624 Localization of RLN3 1 0.05 1 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox