D:Thyroid Crisis

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pChart

Disease Term
Synonyms Crisis Thyroid, CRISIS THYROTOXIC, Storm Thyroid, STORM THYROTOXIC, Thyroid Storm, Thyrotoxic Crisis, Thyrotoxic Storm
Documents 51
Hot Single Events 9
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Thyroid Crisis. They are ordered first by their relevance to Thyroid Crisis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
2 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
3 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
4 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 5.00
5 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Thyroid Crisis. They are ordered first by their pain relevance and then by number of times they were reported in Thyroid Crisis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT107407 Regulation of KCNE1 3 0.39 2.18 0.88 94.88
2 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 94.32
3 INT15229 Positive_regulation of CNDP1 21 0.69 15.86 4.06 93.20
4 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 91.68
5 INT24712 Positive_regulation of Ap3d1 18 0.54 8.58 2.71 91.36
6 INT82404 Negative_regulation of SAA4 3 0.09 3.03 0.38 86.08
7 INT22557 Gene_expression of BMP1 3 0.59 20.18 4.73 82.72
8 INT181636 Positive_regulation of Gene_expression of BMP1 2 0.44 4.46 0.68 82.00
9 INT219392 Positive_regulation of SLC5A8 1 0.41 2.4 0.23 80.96
10 INT219391 Positive_regulation of AIH3 1 0.13 1.26 0.23 79.40
11 INT307632 Regulation of Binding of BMP1 1 0.34 1.53 0.12 75.92
12 INT307631 Positive_regulation of Binding of BMP1 1 0.38 2.99 0.24 75.60
13 INT307634 Binding of BMP1 1 0.36 3.12 3.26 75.20
14 INT142708 Gene_expression of CTSH 1 0.75 1.51 0.18 75.00
15 INT1793 Localization of CGA 379 0.81 67.38 114.69 74.96
16 INT83288 Negative_regulation of NEU4 12 0.51 3.58 0.28 69.56
17 INT307630 Negative_regulation of Localization of BMP1 1 0.32 1.41 0.21 68.24
18 INT307635 Positive_regulation of Localization of BMP1 1 0.38 1.35 0.36 67.36
19 INT282596 Localization of BMP1 2 0.61 4.04 1.97 67.12
20 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 61.84
21 INT207780 Positive_regulation of NMS 2 0.28 3.2 0.61 43.76
22 INT59555 Binding of RYR1 39 0.42 8.65 4.92 34.88
23 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 33.04
24 INT219390 Negative_regulation of DIO1 1 0.19 0.39 0.08 29.36
25 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 29.12
26 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 26.80
27 INT42210 Positive_regulation of TSHB 6 0.49 3.48 1.01 25.00
28 INT2395 Binding of MB 18 0.36 7.53 0.68 24.48
29 INT207781 Gene_expression of CACNA1S 3 0.63 0.9 0.03 20.96
30 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 19.40
31 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 15.04
32 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
33 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
34 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 5.00
35 INT20071 Positive_regulation of HTR2A 33 0.67 10.89 14 5.00
36 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 5.00
37 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 5.00
38 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21 5.00
39 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 5.00
40 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 5.00
41 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66 5.00
42 INT50595 Positive_regulation of HRASLS 16 0.49 9.65 4.24 5.00
43 INT14397 Gene_expression of Serpinc1 27 0.46 14.54 3.32 5.00
44 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
45 INT9549 Regulation of CHKB 25 0.47 13.61 3.2 5.00
46 INT21853 Regulation of Ap3d1 3 0.10 1.4 2.95 5.00
47 INT39463 Positive_regulation of Tg 15 0.69 11.49 2.46 5.00
48 INT4210 Gene_expression of MB 24 0.78 11.74 2.32 5.00
49 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 5.00
50 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98 5.00
51 INT11713 Localization of RYR1 22 0.76 10.42 1.64 5.00
52 INT21852 Regulation of Gene_expression of Ap3d1 2 0.18 1.34 1.54 5.00
53 INT93956 Binding of HBM 20 0.35 8.86 1.48 5.00
54 INT55305 Regulation of RYR1 14 0.45 5.27 1.33 5.00
55 INT11367 Localization of MB 9 0.78 9.34 1.24 5.00
56 INT102231 Localization of HBM 8 0.60 6.14 0.88 5.00
57 INT307628 Negative_regulation of Binding of BMP1 1 0.32 0.05 0.72 5.00
58 INT202715 Binding of NMS 3 0.27 6.92 0.65 5.00
59 INT98609 Negative_regulation of PYGM 11 0.43 6.21 0.6 5.00
60 INT202716 Gene_expression of NMS 4 0.49 4.56 0.57 5.00
61 INT58571 Positive_regulation of ALDOB 6 0.49 5.63 0.53 5.00
62 INT207778 Positive_regulation of Binding of Ap3d1 1 0.06 1.26 0.52 5.00
63 INT45981 Negative_regulation of HRASLS 5 0.13 3.83 0.45 5.00
64 INT135720 Gene_expression of War 7 0.34 3.99 0.28 5.00
65 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25 5.00
66 INT10060 Negative_regulation of MB 7 0.42 2.51 0.22 5.00
67 INT224353 Localization of NMS 1 0.30 1.83 0.2 5.00
68 INT49908 Regulation of Gene_expression of RYR1 3 0.45 0.32 0.19 5.00
69 INT207779 Localization of Ap3d1 1 0.11 3.16 0.14 5.00
70 INT224352 Positive_regulation of Protein_catabolism of SPTB 1 0.01 1.12 0.14 5.00
71 INT224351 Protein_catabolism of SPTB 1 0.01 1.12 0.14 5.00
72 INT307633 Positive_regulation of Positive_regulation of BMP1 1 0.38 0.33 0.11 5.00
73 INT307629 Positive_regulation of BMP1 1 0.53 0.33 0.11 5.00
74 INT307636 Regulation of BMP1 1 0.21 0.32 0.1 5.00
75 INT1571 Negative_regulation of Tshr 2 0.27 2.42 0.07 5.00
76 INT207782 Binding of CACNA1S 1 0.30 0.53 0.03 5.00
77 INT184623 Positive_regulation of Localization of CDKN2A 1 0.04 0.86 0 5.00
78 INT184621 Regulation of ALDOB 1 0.01 1.15 0 5.00
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