D:Tick Infestations

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Disease Term
Synonyms INFESTATION TICK, Infestations Tick, Tick Infestation
Documents 13
Hot Single Events 32
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Tick Infestations. They are ordered first by their relevance to Tick Infestations and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT347021 Cd86 Positive_regulation of Gene_expression of IGHE 1 0.03 0.18 0.05 97.04
2 INT347020 Hand2 Regulation of Gene_expression of Cd86 1 0.08 0.19 0.04 90.92
3 INT347009 Hand2 Regulation of Gene_expression of Il4 1 0.01 0.19 0.04 90.92
4 INT347016 Cd86 Regulation of Gene_expression of Il4 1 0.03 0.19 0.04 90.76
5 INT347018 Cd80 Regulation of Hand2 1 0.03 0.05 0.13 26.08
6 INT347019 Cd80 Regulation of Hand1 1 0.01 0.05 0.13 26.08
7 INT347007 Cd86 Regulation of Hand2 1 0.06 0.05 0.13 25.72
8 INT347014 Cd86 Regulation of Hand1 1 0.02 0.05 0.13 25.72
9 INT347017 Cd86 Positive_regulation of Gene_expression of Il4 1 0.03 0 0.13 20.60
10 INT347015 Hand2 Regulation of Cd86 1 0.06 0 0.14 17.40
11 INT347012 Hand2 Positive_regulation of Il4 1 0.01 0 0.14 14.32
12 INT230584 Positive_regulation of Trpv1 Positive_regulation of Trpm8 1 0.28 0.16 0.37 5.00
13 INT230585 Trpv1 Positive_regulation of Trpm8 1 0.28 0.15 0.36 5.00
14 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27 5.00
15 INT284889 Gene_expression of Hand1 Positive_regulation of Gene_expression of Il4 1 0.21 0.4 0.18 5.00
16 INT347006 Tlr4 Positive_regulation of Cd86 1 0.17 0 0.09 5.00
17 INT347011 Negative_regulation of Mdk Negative_regulation of Regulation of Cd86 1 0.05 0 0.04 5.00
18 INT347013 Il4 Regulation of Gene_expression of Cd86 1 0.02 0.07 0 5.00
19 INT347008 Tlr4 Positive_regulation of Phosphorylation of Mapk14 1 0.02 0.06 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Tick Infestations. They are ordered first by their pain relevance and then by number of times they were reported in Tick Infestations. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT128477 Regulation of Gene_expression of Itga4 1 0.30 0.55 0.09 100.00
2 INT128476 Gene_expression of Itga4 8 0.44 5.61 1.4 99.84
3 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 99.80
4 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 99.58
5 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 99.28
6 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 99.08
7 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 97.04
8 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 94.04
9 INT263492 Positive_regulation of Regulation of Hand2 3 0.19 4.76 0.21 91.24
10 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 90.92
11 INT49405 Gene_expression of Itgal 40 0.75 27.3 4.8 89.92
12 INT117043 Gene_expression of Itga1 4 0.37 3.3 0.77 89.92
13 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 88.88
14 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 88.72
15 INT7561 Positive_regulation of gr 70 0.57 31.92 20.22 88.72
16 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 88.20
17 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 88.16
18 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 88.16
19 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02 87.60
20 INT128478 Positive_regulation of Ptprc 26 0.44 8.1 1.45 87.60
21 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21 87.12
22 INT25386 Positive_regulation of Cd3e 30 0.62 13.91 3.41 87.12
23 INT49406 Positive_regulation of Itgal 7 0.43 8.58 0.95 86.48
24 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 86.36
25 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 86.36
26 INT71766 Transcription of Il10 31 0.69 24.66 10.78 85.96
27 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 85.24
28 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 84.16
29 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 82.44
30 INT120432 Regulation of Trpa1 22 0.61 9.65 12.36 82.44
31 INT134381 Regulation of Trpm8 25 0.54 8.31 8.25 82.44
32 INT60700 Gene_expression of Itgax 93 0.71 51.89 6.57 81.36
33 INT97435 Regulation of Transcription of Il4 2 0.45 0.32 0.18 79.84
34 INT284888 Regulation of Transcription of Hand2 1 0.16 0.32 0.18 79.84
35 INT97438 Transcription of Il4 17 0.67 9.17 3.4 78.48
36 INT100672 Transcription of Hand2 9 0.42 2.84 1.47 76.56
37 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 75.64
38 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 71.08
39 INT96157 Gene_expression of Cd80 74 0.77 31.19 9.78 66.64
40 INT75841 Binding of Trav6-3 66 0.47 29.14 7.63 57.40
41 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 46.40
42 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14 46.40
43 INT111416 Positive_regulation of Trpm8 65 0.70 14.62 17.13 46.40
44 INT230576 Positive_regulation of Trpv3 8 0.46 0.83 2.35 46.40
45 INT3818 Regulation of Apc 13 0.39 12.52 1.68 46.00
46 INT48412 Gene_expression of Apcs 26 0.54 7.16 1.53 43.24
47 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 43.20
48 INT188355 Binding of Cd28 25 0.34 8.29 3.38 38.40
49 INT81249 Positive_regulation of Trpv2 21 0.70 8.13 12.36 37.60
50 INT135990 Positive_regulation of Gene_expression of Cd86 34 0.69 12.02 4.53 37.56
51 INT135991 Positive_regulation of Gene_expression of Cd80 19 0.54 6.9 1.71 37.56
52 INT49996 Regulation of PRDX1 2 0.03 0.64 0.09 29.84
53 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 14.48
54 INT191668 Gene_expression of Phc2 5 0.32 3.25 0.85 14.36
55 INT129240 Positive_regulation of Stat6 6 0.67 1.96 1.92 13.36
56 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
57 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 5.00
58 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
59 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
60 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
61 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
62 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
63 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 5.00
64 INT4830 Binding of Trpv1 158 0.48 45.11 84.2 5.00
65 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 5.00
66 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
67 INT11807 Gene_expression of Il2 266 0.78 112 64.97 5.00
68 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
69 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98 5.00
70 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
71 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 5.00
72 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
73 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76 5.00
74 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
75 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72 5.00
76 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28 5.00
77 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
78 INT117632 Gene_expression of Trpm8 99 0.78 29.41 30.9 5.00
79 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 5.00
80 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
81 INT134651 Binding of TLR4 89 0.48 66.96 23.19 5.00
82 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
83 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 5.00
84 INT171820 Localization of Fig4 144 0.65 27.38 20.88 5.00
85 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09 5.00
86 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 5.00
87 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68 5.00
88 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96 5.00
89 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
90 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67 5.00
91 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59 5.00
92 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21 5.00
93 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
94 INT97848 Positive_regulation of Localization of Trpv1 18 0.50 7.66 13.36 5.00
95 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 5.00
96 INT174844 Binding of Fig4 81 0.41 18.03 12.87 5.00
97 INT96406 Regulation of Trpv2 14 0.62 7.45 12.04 5.00
98 INT55886 Negative_regulation of Gene_expression of Il4 47 0.57 26.04 11.42 5.00
99 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
100 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
101 INT79693 Regulation of Il4 30 0.51 21.96 8.6 5.00
102 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2 5.00
103 INT130502 Negative_regulation of Trpa1 17 0.59 5.75 8.06 5.00
104 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53 5.00
105 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41 5.00
106 INT51741 Regulation of Gene_expression of Il4 23 0.36 12.7 7.39 5.00
107 INT14732 Positive_regulation of FN1 46 0.69 31.17 7.33 5.00
108 INT134379 Binding of Trpa1 13 0.48 7.16 7.27 5.00
109 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 5.00
110 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97 5.00
111 INT218698 Negative_regulation of Positive_regulation of Fig4 11 0.20 6.01 6.32 5.00
112 INT139580 Negative_regulation of Trpm8 19 0.58 3.8 6.26 5.00
113 INT142607 Positive_regulation of Gene_expression of Cd40 41 0.62 13.85 5.51 5.00
114 INT141275 Negative_regulation of Gene_expression of Hand1 18 0.34 15.83 5.05 5.00
115 INT142162 Binding of IL10 30 0.37 21.9 4.84 5.00
116 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 5.00
117 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46 5.00
118 INT102850 Gene_expression of Trpv3 12 0.56 2.06 4.01 5.00
119 INT59836 Positive_regulation of Upf1 24 0.02 4.42 3.99 5.00
120 INT43931 Binding of CFH 49 0.48 31.85 3.96 5.00
121 INT124028 Localization of Trpv2 6 0.80 2.04 3.96 5.00
122 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87 5.00
123 INT36892 Positive_regulation of Trav6-3 57 0.68 12.15 3.8 5.00
124 INT187505 Positive_regulation of Localization of Fig4 16 0.24 1.21 3.17 5.00
125 INT61500 Binding of FN1 39 0.48 27.33 3.13 5.00
126 INT134378 Binding of Trpm8 8 0.48 1.74 2.95 5.00
127 INT221097 Negative_regulation of Atp8a1 15 0.57 10.52 2.65 5.00
128 INT96154 Negative_regulation of Gene_expression of Cd86 10 0.48 3.76 2.35 5.00
129 INT92542 Negative_regulation of Trpv2 8 0.59 1.54 2.15 5.00
130 INT228401 Positive_regulation of Cd86 24 0.53 6.46 1.8 5.00
131 INT124639 Localization of Trpv3 4 0.49 0.69 1.74 5.00
132 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74 5.00
133 INT165213 Regulation of Gene_expression of Cd4 12 0.40 9.14 1.57 5.00
134 INT237377 Regulation of Gene_expression of Cd86 10 0.47 3.64 1.52 5.00
135 INT199144 Regulation of Trpv3 2 0.30 0.79 1.48 5.00
136 INT130241 Positive_regulation of Positive_regulation of Trpm8 5 0.69 0.15 1.45 5.00
137 INT59837 Regulation of Upf1 5 0.03 1.37 1.45 5.00
138 INT127323 Positive_regulation of Positive_regulation of Trpa1 8 0.69 0.96 1.42 5.00
139 INT141131 Positive_regulation of Gene_expression of PRNP 12 0.61 16.6 1.36 5.00
140 INT181526 Positive_regulation of Apcs 13 0.49 4.09 1.3 5.00
141 INT204772 Negative_regulation of Gene_expression of Mthfd1 10 0.15 3.48 1.29 5.00
142 INT223121 Positive_regulation of Positive_regulation of Mdk 6 0.20 2.7 1.27 5.00
143 INT151513 Negative_regulation of Gene_expression of Pecam1 8 0.37 4.73 1.22 5.00
144 INT189836 Regulation of Cd40 10 0.40 3.02 1.1 5.00
145 INT135527 Negative_regulation of Gene_expression of Cd4 17 0.43 6.72 1.09 5.00
146 INT230575 Negative_regulation of Gene_expression of Trpv3 2 0.28 0.57 0.73 5.00
147 INT302544 Regulation of Cd86 10 0.34 1.89 0.62 5.00
148 INT230581 Positive_regulation of Regulation of Trpv3 1 0.31 0 0.55 5.00
149 INT230579 Positive_regulation of Localization of Trpv2 1 0.32 0 0.55 5.00
150 INT230573 Positive_regulation of Localization of Trpv3 1 0.33 0 0.55 5.00
151 INT230574 Binding of Trpv3 1 0.25 0 0.53 5.00
152 INT183164 Regulation of Cd80 6 0.33 2.69 0.52 5.00
153 INT230577 Negative_regulation of Trpv3 1 0.28 0 0.46 5.00
154 INT230572 Negative_regulation of Gene_expression of Trpv2 1 0.28 0.28 0.43 5.00
155 INT59838 Positive_regulation of Positive_regulation of Upf1 3 0.01 0.64 0.37 5.00
156 INT278194 Protein_catabolism of Il4 2 0.57 1.12 0.3 5.00
157 INT331559 Positive_regulation of Positive_regulation of Apcs 1 0.21 0.8 0.22 5.00
158 INT230578 Regulation of Negative_regulation of Trpv1 1 0.32 0 0.2 5.00
159 INT284541 Positive_regulation of Positive_regulation of Cd86 2 0.33 1.44 0.19 5.00
160 INT146898 Positive_regulation of Binding of CFH 3 0.44 2.01 0.17 5.00
161 INT230580 Negative_regulation of Positive_regulation of Trpv2 1 0.28 0 0.1 5.00
162 INT274290 Binding of Fhl1 3 0.03 1.16 0.1 5.00
163 INT346994 Regulation of Regulation of Cd86 1 0.28 0.29 0.07 5.00
164 INT196391 Transcription of Cd86 2 0.44 0.78 0.05 5.00
165 INT196394 Positive_regulation of Transcription of Cd86 2 0.43 0.79 0.05 5.00
166 INT280115 Transcription of Cd80 3 0.30 2.63 0.05 5.00
167 INT346995 Negative_regulation of Positive_regulation of Cd86 1 0.26 0.09 0.03 5.00
168 INT230181 Binding of Aurka 2 0.35 0.63 0.03 5.00
169 INT230194 Negative_regulation of Gene_expression of PISRT1 1 0.30 0.81 0 5.00
170 INT230198 Gene_expression of LDLRAP1 1 0.06 0.87 0 5.00
171 INT230195 Negative_regulation of LDLRAP1 1 0.04 0.88 0 5.00
172 INT230196 Positive_regulation of Transcription of PISRT1 1 0.34 0.4 0 5.00
173 INT230193 Transcription of PISRT1 1 0.49 0.4 0 5.00
174 INT230199 Regulation of Transcription of PISRT1 1 0.19 0.4 0 5.00
175 INT230200 Gene_expression of PISRT1 1 0.53 0.8 0 5.00
176 INT230197 Binding of LDLRAP1 1 0.03 0.63 0 5.00
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