D:Treatment-resistant Depression (TRD)

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Treatment Resistant Depression
Documents 23
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Treatment-resistant Depression (TRD). They are ordered first by their relevance to Treatment-resistant Depression (TRD) and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT301166 LRP2 Regulation of TRD@ 1 0.12 1.93 1.21 5.00
2 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48 5.00
3 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48 5.00
4 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47 5.00
5 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47 5.00
6 INT179689 Binding of CYP4F3 and DAK 1 0.00 1.23 0.2 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Treatment-resistant Depression (TRD). They are ordered first by their pain relevance and then by number of times they were reported in Treatment-resistant Depression (TRD). Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT64505 Localization of Htr2c 3 0.78 0.87 2.24 100.00
2 INT101340 Localization of MTNR1A 3 0.55 2.07 1.04 100.00
3 INT288625 Localization of MT2A 1 0.46 0.46 0.95 100.00
4 INT145425 Positive_regulation of NLRP1 19 0.47 6.93 12.09 98.40
5 INT242110 Regulation of IGKV1-22 2 0.06 2.02 0.52 96.80
6 INT14132 Negative_regulation of HTR1A 25 0.57 4.93 10.91 95.48
7 INT288626 Localization of HTR2B 1 0.05 0.4 0.9 90.64
8 INT139662 Gene_expression of FGF9 7 0.65 2.26 0.17 87.92
9 INT224814 Regulation of EGOT 2 0.17 0.79 0.39 86.40
10 INT4682 Positive_regulation of EGOT 2 0.42 2.32 1.28 85.68
11 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 81.92
12 INT91991 Negative_regulation of IGKV1-22 2 0.57 2.55 1.67 76.68
13 INT7439 Positive_regulation of CFP 52 0.67 19.97 17.87 63.20
14 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13 52.48
15 INT177611 Binding of EGOT 2 0.23 1.72 0.62 45.20
16 INT179101 Gene_expression of CYP4F3 14 0.65 6.89 1.98 41.12
17 INT145937 Regulation of PCS 32 0.39 19.25 1.97 38.64
18 INT170768 Regulation of Gene_expression of NR3C1 3 0.42 2.61 0.58 32.88
19 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55 31.64
20 INT173916 Regulation of LRP2 6 0.44 7.96 1.14 30.84
21 INT52402 Negative_regulation of Htr2c 7 0.42 1.46 4.21 26.96
22 INT179695 Negative_regulation of CYP4F3 4 0.45 4.94 1.38 22.08
23 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 9.68
24 INT103477 Negative_regulation of Gene_expression of BDNF 23 0.52 10.63 6.26 9.68
25 INT242113 Gene_expression of EGOT 1 0.41 3.06 0.71 5.12
26 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 5.00
27 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
28 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
29 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 5.00
30 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
31 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 5.00
32 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 5.00
33 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 5.00
34 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 5.00
35 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35 5.00
36 INT164366 Localization of NLRP1 26 0.71 5.9 16.54 5.00
37 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
38 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
39 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 5.00
40 INT94545 Positive_regulation of C7orf49 37 0.69 12.91 11.19 5.00
41 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 5.00
42 INT179696 Negative_regulation of DAK 5 0.02 16.79 9.42 5.00
43 INT27785 Regulation of HTR2A 11 0.44 8 8.18 5.00
44 INT7813 Regulation of SRI 25 0.61 6.18 8.13 5.00
45 INT36678 Binding of TIMP1 33 0.36 14.99 7.87 5.00
46 INT9032 Regulation of Htr2c 11 0.60 2.77 7.81 5.00
47 INT126314 Positive_regulation of OFC1 25 0.54 7.65 7.39 5.00
48 INT20331 Positive_regulation of CYP1A2 31 0.69 8.6 5.92 5.00
49 INT77955 Negative_regulation of PCS 55 0.43 39.32 5.76 5.00
50 INT102836 Binding of LRP2 12 0.38 11.27 5.58 5.00
51 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75 5.00
52 INT31810 Binding of HTR2B 6 0.47 2.75 4.36 5.00
53 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09 5.00
54 INT7437 Gene_expression of CFP 21 0.65 4.93 3.89 5.00
55 INT125622 Regulation of NLRP1 7 0.44 1.84 3.62 5.00
56 INT27660 Binding of CFP 21 0.40 12.47 3.51 5.00
57 INT66617 Localization of HTR2A 6 0.80 1.35 3.32 5.00
58 INT28852 Negative_regulation of OFC1 11 0.42 4.23 3.24 5.00
59 INT18148 Binding of Htr1f 4 0.47 2.05 3.23 5.00
60 INT54369 Regulation of VTA1 4 0.38 3.03 3.18 5.00
61 INT52403 Negative_regulation of HTR2B 5 0.42 1.79 3.15 5.00
62 INT39344 Gene_expression of DNASE1L3 12 0.54 2.25 2.88 5.00
63 INT8112 Regulation of EPO 38 0.58 22.04 2.76 5.00
64 INT242107 Positive_regulation of SYNM 8 0.38 2.82 2.39 5.00
65 INT262364 Positive_regulation of LRP2 6 0.39 4.44 1.97 5.00
66 INT221127 Positive_regulation of IGKV1-22 2 0.17 4.7 1.93 5.00
67 INT134673 Gene_expression of SYNM 16 0.75 2.72 1.62 5.00
68 INT238317 Gene_expression of TRD@ 5 0.16 1.65 1.61 5.00
69 INT193405 Gene_expression of OFC1 14 0.53 3.33 1.42 5.00
70 INT179693 Positive_regulation of DAK 14 0.04 6.02 1.4 5.00
71 INT242105 Positive_regulation of Positive_regulation of CFP 5 0.49 1.93 1.32 5.00
72 INT109255 Gene_expression of IFNW1 4 0.02 2.72 1.3 5.00
73 INT94532 Regulation of MT2A 5 0.36 4.25 0.98 5.00
74 INT179698 Positive_regulation of CYP4F3 5 0.54 3.86 0.91 5.00
75 INT179697 Regulation of CYP4F3 4 0.47 4.36 0.83 5.00
76 INT221129 Gene_expression of IGKV1-22 5 0.22 1.73 0.78 5.00
77 INT122657 Positive_regulation of MTNR1A 9 0.49 4.14 0.76 5.00
78 INT238316 Positive_regulation of Gene_expression of TRD@ 2 0.11 0.77 0.64 5.00
79 INT301167 Localization of TRD@ 1 0.17 1.37 0.59 5.00
80 INT242112 Positive_regulation of Gene_expression of IGKV1-22 1 0.08 0.99 0.47 5.00
81 INT179102 Binding of CYP4F3 4 0.29 1.75 0.41 5.00
82 INT301168 Localization of LRP2 1 0.59 0.83 0.36 5.00
83 INT275327 Binding of TRD@ 1 0.02 0.99 0.34 5.00
84 INT242104 Transcription of CFP 2 0.44 0.86 0.32 5.00
85 INT144387 Positive_regulation of Negative_regulation of CYP1A2 2 0.39 0.64 0.28 5.00
86 INT242109 Transcription of OFC1 1 0.33 0.61 0.28 5.00
87 INT288627 Positive_regulation of MT2A 1 0.33 0.3 0.23 5.00
88 INT179692 Positive_regulation of IFNW1 1 0.01 0.52 0.22 5.00
89 INT179694 Positive_regulation of Positive_regulation of IFNW1 1 0.01 0.57 0.22 5.00
90 INT242111 Binding of IGKV1-22 2 0.06 1.47 0.2 5.00
91 INT242103 Negative_regulation of Positive_regulation of IGKV1-22 1 0.06 0.85 0.16 5.00
92 INT242108 Positive_regulation of Positive_regulation of IGKV1-22 1 0.08 0.87 0.16 5.00
93 INT242106 Positive_regulation of Positive_regulation of SYNM 1 0.24 0.54 0.12 5.00
94 INT221128 Localization of IGKV1-22 2 0.25 0.1 0.06 5.00
95 INT269274 Regulation of MTNR1A 3 0.60 1.47 0.05 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox