D:Trismus

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Lock Jaw, LOCKJAW, Masseter Muscle Spasm, Masseter Muscle Spasms, Masseter Spasm, MASSETER SPASMS, Muscle Spasm Masseter, Muscle Spasms Masseter, SPASM MASSETER, Spasm Masseter Muscle, Spasms Masseter
Documents 429
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Trismus. They are ordered first by their relevance to Trismus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT346412 Binding of Tesc and Sv2a 1 0.02 0.6 0.59 5.00
2 INT346416 Binding of Tesc and Svs1 1 0.00 0.07 0.42 5.00
3 INT346409 Negative_regulation of Binding of mn and Tesc 1 0.00 0.29 0.22 5.00
4 INT346408 Binding of mn and Tesc 1 0.00 0.29 0.22 5.00
5 INT346414 Thy1 Positive_regulation of Binding of Tesc 1 0.00 0.16 0.15 5.00
6 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15 5.00
7 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15 5.00
8 INT346411 Binding of Caprin1 and Mtus1 1 0.00 0.17 0.14 5.00
9 INT346410 Binding of Caprin1 and Tesc 1 0.00 0.17 0.14 5.00
10 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14 5.00
11 INT346415 Binding of Mns1 and Sv2a 1 0.03 0.14 0.07 5.00
12 INT204246 ETFA Regulation of CD68 1 0.37 1.05 0.04 5.00
13 INT346418 Sv2a Positive_regulation of Binding of Tesc 1 0.02 0.1 0.04 5.00
14 INT204247 S100B Regulation of CD68 1 0.03 1.05 0.04 5.00
15 INT346407 Negative_regulation of Binding of Tesc and Sv2a 1 0.02 0 0.03 5.00
16 INT265964 TNNI2 Regulation of CA2 1 0.22 0.09 0 5.00
17 INT332136 POGLUT1 Negative_regulation of HJURP 1 0.00 0.06 0 5.00
18 INT332135 POGLUT1 Negative_regulation of NLRP5 1 0.00 0.06 0 5.00
19 INT332069 POGLUT1 Negative_regulation of fd 1 0.00 0.06 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Trismus. They are ordered first by their pain relevance and then by number of times they were reported in Trismus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 99.66
2 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 98.50
3 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 97.28
4 INT206795 Localization of VAMP7 1 0.57 1.17 0 96.12
5 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 94.00
6 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 93.36
7 INT10799 Localization of ENG 63 0.78 18.67 27.28 91.32
8 INT51869 Negative_regulation of Dmd 24 0.52 10.4 2.18 89.24
9 INT234 Binding of Alb 151 0.48 52.34 32.97 85.56
10 INT76227 Binding of NPC1 30 0.41 32.31 4.05 84.72
11 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 82.24
12 INT5489 Localization of CA2 172 0.80 39.46 33.56 77.84
13 INT346404 Gene_expression of Sv2a 1 0.72 3.2 1.62 76.16
14 INT346396 Positive_regulation of Gene_expression of Sv2a 1 0.43 1.09 0.26 76.16
15 INT206797 Negative_regulation of VAMP7 1 0.35 1.68 0.22 73.24
16 INT332059 Negative_regulation of NLRP5 1 0.00 0.57 0 71.12
17 INT88195 Gene_expression of ZAK 15 0.74 4.79 1.55 70.24
18 INT111770 Regulation of PMEL 2 0.44 0.4 0.12 68.88
19 INT18114 Gene_expression of NPC1 45 0.66 57.85 1.44 67.24
20 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 65.24
21 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 65.24
22 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 64.64
23 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 62.92
24 INT346381 Localization of Sv2a 1 0.69 1.12 0.61 62.64
25 INT265969 Regulation of TNNI2 1 0.45 1.35 0.09 60.56
26 INT265966 Regulation of MYH3 1 0.44 1.35 0.09 60.56
27 INT959 Regulation of ATRX 5 0.47 5.04 0.89 60.24
28 INT346400 Localization of Sv2b 1 0.49 1.15 0.48 59.76
29 INT962 Gene_expression of ATRX 2 0.59 1.72 0.27 58.00
30 INT265972 Positive_regulation of Gene_expression of ATRX 1 0.38 1.72 0 58.00
31 INT332064 Gene_expression of NLRP5 1 0.01 0.54 0 34.64
32 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 33.16
33 INT346375 Protein_catabolism of Vamp2 1 0.33 1.56 2.46 25.00
34 INT208874 Gene_expression of Sv2b 6 0.54 0.98 1.65 25.00
35 INT265968 Gene_expression of TNNT3 1 0.65 1.39 0 19.76
36 INT265967 Gene_expression of TNNI2 1 0.67 1.39 0 18.96
37 INT265971 Gene_expression of MYH3 1 0.66 1.2 0 18.40
38 INT147793 Localization of COPD 70 0.64 89.01 7.3 18.36
39 INT177586 Positive_regulation of Gene_expression of MRI1 9 0.33 4.97 2.91 17.24
40 INT5789 Gene_expression of PMEL 23 0.75 13.18 2.67 13.60
41 INT106952 Positive_regulation of NPC1 23 0.43 22.9 0.94 7.72
42 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
43 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
44 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
45 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
46 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
47 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
48 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 5.00
49 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
50 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
51 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
52 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
53 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
54 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 5.00
55 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 5.00
56 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
57 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
58 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
59 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 5.00
60 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
61 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
62 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 5.00
63 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 5.00
64 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
65 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
66 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 5.00
67 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
68 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 5.00
69 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
70 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
71 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
72 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 5.00
73 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 5.00
74 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 5.00
75 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
76 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48 5.00
77 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
78 INT18621 Binding of ABAT 28 0.36 9.88 18.04 5.00
79 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 5.00
80 INT72564 Localization of Il10 41 0.78 28.62 17.6 5.00
81 INT22068 Binding of CALCRL 53 0.41 6.14 17.32 5.00
82 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 5.00
83 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 5.00
84 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
85 INT19071 Localization of Ache 66 0.81 5.1 16.27 5.00
86 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
87 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 5.00
88 INT40478 Negative_regulation of NCOR2 23 0.48 12.77 14.56 5.00
89 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 5.00
90 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 5.00
91 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
92 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02 5.00
93 INT30961 Binding of HTR2A 33 0.47 11.44 12.86 5.00
94 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
95 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 5.00
96 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
97 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
98 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91 5.00
99 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 5.00
100 INT10019 Binding of CD8A 57 0.36 31.49 10.08 5.00
101 INT5465 Positive_regulation of CALCRL 25 0.49 7.24 9.8 5.00
102 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
103 INT26795 Gene_expression of Mtpn 44 0.62 27.66 8.62 5.00
104 INT61585 Gene_expression of NALCN 25 0.52 6.52 8.18 5.00
105 INT29229 Regulation of NCOR2 20 0.42 5.75 8.08 5.00
106 INT25585 Positive_regulation of DNAH8 39 0.70 17.96 7.85 5.00
107 INT1150 Gene_expression of ecs 42 0.59 29.38 7.73 5.00
108 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 5.00
109 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
110 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 5.00
111 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
112 INT64689 Positive_regulation of Gene_expression of Fgf2 30 0.70 12.05 6.2 5.00
113 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 5.00
114 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
115 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16 5.00
116 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 5.00
117 INT17489 Regulation of F13A1 28 0.45 15.79 4.93 5.00
118 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
119 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 5.00
120 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22 5.00
121 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 5.00
122 INT68269 Gene_expression of CD99 49 0.77 47.38 3.86 5.00
123 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 5.00
124 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47 5.00
125 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 5.00
126 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 5.00
127 INT170606 Regulation of Gene_expression of GOPC 31 0.37 6.08 3.31 5.00
128 INT40165 Binding of Fbxo23 7 0.30 1.18 3.26 5.00
129 INT346398 Binding of Tesc 1 0.02 1.88 3.14 5.00
130 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79 5.00
131 INT133144 Localization of Mtpn 18 0.24 7.88 2.77 5.00
132 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 5.00
133 INT24895 Positive_regulation of LYZ 25 0.70 17.92 2.64 5.00
134 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 5.00
135 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 5.00
136 INT249378 Negative_regulation of Vamp2 3 0.20 0.27 2.4 5.00
137 INT156373 Binding of Sv2a 4 0.39 1.54 2.3 5.00
138 INT37394 Localization of ecs 9 0.34 6.41 2.11 5.00
139 INT83896 Gene_expression of CD1A 19 0.68 15.58 2.1 5.00
140 INT20388 Binding of LYZ 8 0.39 5.65 1.93 5.00
141 INT106153 Gene_expression of HJURP 5 0.04 2.33 1.85 5.00
142 INT169862 Regulation of NPC1 13 0.53 13.61 1.84 5.00
143 INT38201 Negative_regulation of Localization of Ache 8 0.59 2.35 1.82 5.00
144 INT114490 Gene_expression of PDLIM7 17 0.78 11.35 1.42 5.00
145 INT153757 Positive_regulation of Mitf 10 0.46 8.38 1.22 5.00
146 INT139261 Positive_regulation of Gene_expression of Mtpn 8 0.05 5.95 1.22 5.00
147 INT122988 Gene_expression of CLU 28 0.75 24.07 1.21 5.00
148 INT177492 Positive_regulation of Slc32a1 3 0.45 1.25 1.09 5.00
149 INT184841 Localization of Snap25 12 0.81 1.45 1.09 5.00
150 INT183933 Binding of CD68 8 0.31 8.74 1.06 5.00
151 INT90240 Gene_expression of MYOG 19 0.75 10 1.06 5.00
152 INT249383 Binding of Vamp2 5 0.23 0.33 1.03 5.00
153 INT177615 Gene_expression of PAX7 20 0.65 13.5 1.03 5.00
154 INT41315 Localization of Fbxo23 4 0.66 0.78 1.01 5.00
155 INT140497 Positive_regulation of NALCN 4 0.31 1.03 1 5.00
156 INT161591 Positive_regulation of CD163 5 0.48 3.9 0.98 5.00
157 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 5.00
158 INT234081 Gene_expression of Vamp2 9 0.51 0.71 0.94 5.00
159 INT55566 Gene_expression of Dct 5 0.36 1.13 0.94 5.00
160 INT249377 Localization of Vamp2 4 0.51 0.4 0.93 5.00
161 INT246311 Protein_catabolism of Snap25 6 0.66 1.15 0.89 5.00
162 INT68228 Positive_regulation of TNFRSF8 5 0.56 6.26 0.84 5.00
163 INT125627 Gene_expression of TTF1 11 0.78 12.68 0.78 5.00
164 INT227255 Gene_expression of fd 3 0.07 1.58 0.77 5.00
165 INT167381 Localization of DES 4 0.73 4.15 0.77 5.00
166 INT190781 Binding of Acsl1 6 0.36 9.12 0.76 5.00
167 INT248378 Localization of GRK4 3 0.00 0.69 0.69 5.00
168 INT346390 Binding of Svs1 1 0.05 0.42 0.65 5.00
169 INT177611 Binding of EGOT 2 0.23 1.72 0.62 5.00
170 INT204254 Localization of KIT 8 0.73 6.78 0.61 5.00
171 INT346389 Negative_regulation of Sv2a 1 0.47 0.41 0.61 5.00
172 INT346406 Gene_expression of Mns1 2 0.12 0.27 0.6 5.00
173 INT91209 Binding of VIM 15 0.36 12.02 0.53 5.00
174 INT346370 Regulation of Localization of Vamp2 1 0.15 0.08 0.53 5.00
175 INT346393 Regulation of Protein_catabolism of Vamp2 1 0.09 0.08 0.53 5.00
176 INT107118 Positive_regulation of ALK 4 0.49 3.64 0.52 5.00
177 INT177610 Positive_regulation of Localization of Fbxo23 3 0.04 0.91 0.47 5.00
178 INT336690 Negative_regulation of Gene_expression of Vamp2 2 0.16 0.28 0.46 5.00
179 INT228320 Gene_expression of POGLUT1 6 0.07 1.95 0.45 5.00
180 INT156997 Localization of NPC1 19 0.64 30 0.42 5.00
181 INT204258 Binding of NSMCE1 4 0.36 6.41 0.42 5.00
182 INT346391 Localization of Svs1 1 0.10 0 0.41 5.00
183 INT97450 Gene_expression of Mitf 36 0.75 17.22 0.39 5.00
184 INT153260 Gene_expression of CD22 19 0.70 8.35 0.39 5.00
185 INT961 Positive_regulation of ATRX 3 0.53 1.99 0.36 5.00
186 INT346378 Positive_regulation of Svs1 1 0.06 0 0.31 5.00
187 INT346405 Localization of Mns1 1 0.05 0.44 0.29 5.00
188 INT346373 Negative_regulation of Binding of Sv2b 1 0.26 0.21 0.27 5.00
189 INT206798 Binding of VAMP7 1 0.30 2.23 0.26 5.00
190 INT346374 Binding of Sv2b 1 0.22 0.31 0.26 5.00
191 INT191072 Gene_expression of Dtc1 3 0.01 0.77 0.25 5.00
192 INT201570 Gene_expression of CR2 11 0.48 14.21 0.22 5.00
193 INT346376 Localization of Tesc 1 0.03 1 0.22 5.00
194 INT68056 Gene_expression of NSMCE1 2 0.14 0.49 0.2 5.00
195 INT346369 Gene_expression of Tesc 1 0.03 1.37 0.18 5.00
196 INT346382 Regulation of Sv2a 1 0.36 0 0.17 5.00
197 INT346383 Gene_expression of Sv2c 1 0.23 0.21 0.17 5.00
198 INT134223 Localization of CD99 4 0.73 4.42 0.16 5.00
199 INT346392 Regulation of Tesc 1 0.01 0.27 0.16 5.00
200 INT213794 Phosphorylation of Mitf 2 0.42 2.56 0.15 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox