D:Urinary Tract Cancer

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pChart

Disease Term
Synonyms CANCER OF THE URINARY TRACT, Cancer Of Urinary Tract, Cancer Urinary Tract, Cancer Urologic, CANCER UROLOGICAL, Cancers Urinary Tract, Cancers Urologic, Cancers Urological, Neoplasm Urinary Tract, Neoplasm Urologic, Neoplasm Urological
Documents 104
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Urinary Tract Cancer. They are ordered first by their relevance to Urinary Tract Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56 5.00
2 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
3 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15 5.00
4 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 5.00
5 INT276141 Binding of Gh and Igf1 2 0.34 0.66 0.08 5.00
6 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05 5.00
7 INT331172 Binding of IFNA1 and IL2 1 0.00 0.46 0.04 5.00
8 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0 5.00
9 INT290556 Binding of MLH1 and MSH2 3 0.34 2.74 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Urinary Tract Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Urinary Tract Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 99.76
2 INT74018 Binding of XRCC1 19 0.31 24.78 1.24 99.32
3 INT89603 Regulation of Negative_regulation of Cpox 11 0.30 10.59 6.28 98.00
4 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 97.78
5 INT179043 Negative_regulation of Cdkn1b 7 0.36 5.99 0.22 94.64
6 INT92139 Binding of MLH1 12 0.42 15.62 1 94.32
7 INT323131 Negative_regulation of TRDV1 1 0.01 0.65 0 91.04
8 INT92142 Binding of MSH2 5 0.46 5.64 0.75 90.60
9 INT163828 Localization of Cdkn1b 4 0.66 5.2 0.48 88.16
10 INT86910 Negative_regulation of MRC1 6 0.20 6.52 0.8 86.24
11 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 85.40
12 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18 77.68
13 INT179033 Negative_regulation of Regulation of Cdkn1b 1 0.36 1.34 0.05 77.68
14 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 75.04
15 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 74.68
16 INT1893 Localization of Gh 1041 0.79 340.23 256.58 74.04
17 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 74.04
18 INT78990 Regulation of Cpox 72 0.57 35.22 18.16 74.00
19 INT146546 Gene_expression of MSI1 22 0.48 22.91 1.15 71.68
20 INT97973 Positive_regulation of XRCC1 24 0.40 30.95 2.26 70.52
21 INT339094 Gene_expression of Ezh2 1 0.78 67.79 0.05 70.40
22 INT339091 Positive_regulation of Gene_expression of Ezh2 1 0.70 11.65 0 70.40
23 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 67.40
24 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71 67.40
25 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 67.00
26 INT339095 Negative_regulation of Gene_expression of Ezh2 1 0.59 4.48 0 63.88
27 INT179038 Positive_regulation of Regulation of Bcl2 1 0.39 3.49 0.12 63.12
28 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 62.76
29 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 54.08
30 INT339088 Negative_regulation of Gene_expression of Rcc1 1 0.02 1.37 0 52.44
31 INT339092 Gene_expression of Rcc1 1 0.04 6.37 0 51.24
32 INT179036 Gene_expression of Fez1 1 0.70 13.28 0.11 48.84
33 INT323133 Negative_regulation of Phosphorylation of CD8A 1 0.04 0.27 0 47.32
34 INT253647 Phosphorylation of CD8A 3 0.25 0.7 0.29 46.80
35 INT120519 Localization of XRCC1 15 0.78 17.03 1.51 43.20
36 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 25.92
37 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 16.40
38 INT50290 Binding of Cpox 29 0.27 17.19 8.01 12.32
39 INT339089 Regulation of Gene_expression of Ezh2 1 0.45 3.76 0 12.32
40 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 8.92
41 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24 7.04
42 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
43 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
44 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
45 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
46 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
47 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 5.00
48 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
49 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
50 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
51 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
52 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
53 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
54 INT403 Localization of Trh 241 0.81 28.55 81.45 5.00
55 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
56 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83 5.00
57 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
58 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 5.00
59 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
60 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
61 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
62 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5 5.00
63 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
64 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 5.00
65 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 5.00
66 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
67 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 5.00
68 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 5.00
69 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
70 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 5.00
71 INT10763 Localization of IL2 157 0.80 81.11 33.21 5.00
72 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
73 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 5.00
74 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
75 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
76 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76 5.00
77 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
78 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
79 INT1327 Regulation of Localization of Trh 45 0.62 6.05 22.09 5.00
80 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 5.00
81 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 5.00
82 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
83 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 5.00
84 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 5.00
85 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
86 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 5.00
87 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
88 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
89 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
90 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 5.00
91 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
92 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
93 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07 5.00
94 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 5.00
95 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 5.00
96 INT28861 Binding of Gh 61 0.46 25.61 6.38 5.00
97 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26 5.00
98 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 5.00
99 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 5.00
100 INT26585 Gene_expression of Vim 117 0.77 39.97 6 5.00
101 INT39047 Gene_expression of PGF 34 0.78 17.48 6 5.00
102 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
103 INT38556 Gene_expression of DBT 47 0.50 12.52 5.6 5.00
104 INT11062 Positive_regulation of MME 24 0.63 14.37 5.26 5.00
105 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 5.00
106 INT174193 Gene_expression of LILRA3 20 0.28 12.65 5.1 5.00
107 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 5.00
108 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 5.00
109 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05 5.00
110 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 5.00
111 INT149259 Gene_expression of RCT 38 0.67 15.73 3.87 5.00
112 INT117614 Positive_regulation of PAPPA 18 0.67 11.9 3.76 5.00
113 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 5.00
114 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 5.00
115 INT10188 Positive_regulation of Il2ra 19 0.45 11.6 3.37 5.00
116 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76 5.00
117 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62 5.00
118 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59 5.00
119 INT102036 Positive_regulation of Dre 12 0.59 4.41 2.4 5.00
120 INT38871 Binding of TFPI 12 0.32 5.9 2.36 5.00
121 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92 5.00
122 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9 5.00
123 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6 5.00
124 INT89445 Gene_expression of MEPE 17 0.58 18.07 1.55 5.00
125 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46 5.00
126 INT90491 Binding of Igf1 25 0.44 9.75 1.36 5.00
127 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15 5.00
128 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14 5.00
129 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12 5.00
130 INT58347 Positive_regulation of BAG1 4 0.45 3.42 0.93 5.00
131 INT120693 Positive_regulation of MEPE 7 0.50 8.22 0.79 5.00
132 INT20765 Negative_regulation of INHBA 6 0.34 1.91 0.77 5.00
133 INT140637 Negative_regulation of IFI27 11 0.40 9.48 0.69 5.00
134 INT106613 Regulation of IFI27 6 0.57 3.12 0.66 5.00
135 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 5.00
136 INT211714 Regulation of Gene_expression of VIM 4 0.43 3.77 0.52 5.00
137 INT20766 Positive_regulation of INHBA 4 0.66 5.66 0.48 5.00
138 INT96864 Localization of Plg 7 0.67 2.07 0.48 5.00
139 INT7067 Negative_regulation of Gene_expression of SHBG 7 0.41 5.08 0.48 5.00
140 INT158019 Positive_regulation of Gene_expression of FLT1 20 0.68 9.73 0.44 5.00
141 INT96816 Regulation of APOE 8 0.45 6.62 0.44 5.00
142 INT111489 Gene_expression of HAS3 3 0.61 1.91 0.39 5.00
143 INT158641 Positive_regulation of CHEK2 5 0.35 4.15 0.37 5.00
144 INT39715 Negative_regulation of PGF 3 0.41 1.22 0.31 5.00
145 INT103446 Gene_expression of Krt10 4 0.39 2.21 0.29 5.00
146 INT107983 Gene_expression of MSH6 6 0.51 5.57 0.27 5.00
147 INT123733 Gene_expression of Fhit 5 0.78 12.34 0.26 5.00
148 INT204721 Localization of FLT1 30 0.73 4.64 0.15 5.00
149 INT179034 Binding of Cdkn1b 7 0.31 5.12 0.12 5.00
150 INT211717 Gene_expression of CHEK2 13 0.37 2.13 0.1 5.00
151 INT153294 Binding of FIP1L1 1 0.36 0.7 0.08 5.00
152 INT124011 Negative_regulation of Fhit 2 0.57 1.57 0.07 5.00
153 INT179039 Negative_regulation of Gene_expression of Fez1 1 0.52 6.07 0.07 5.00
154 INT124007 Regulation of Fhit 2 0.48 2.43 0.07 5.00
155 INT264172 Positive_regulation of Gene_expression of RCT 5 0.40 0.56 0.06 5.00
156 INT323132 Negative_regulation of ZNF77 1 0.42 1.05 0.06 5.00
157 INT179032 Negative_regulation of Cdcs1 1 0.04 1.39 0.06 5.00
158 INT179037 Negative_regulation of Fez1 1 0.39 3.52 0.06 5.00
159 INT199551 Regulation of Rcc1 2 0.01 2.63 0.05 5.00
160 INT170852 Negative_regulation of Gene_expression of IFI27 16 0.55 8.62 0.05 5.00
161 INT251463 Negative_regulation of Inha 1 0.41 0.68 0.03 5.00
162 INT331173 Negative_regulation of Localization of Plg 1 0.02 0.67 0 5.00
163 INT107988 Regulation of MRC1 2 0.40 0.56 0 5.00
164 INT179045 Gene_expression of BLZF1 4 0.04 2.42 0 5.00
165 INT331174 Localization of Pdgfc 1 0.03 0.54 0 5.00
166 INT339087 Binding of Ezh2 1 0.37 1.14 0 5.00
167 INT251465 Positive_regulation of Inha 1 0.67 1.8 0 5.00
168 INT278080 Regulation of Gene_expression of RCT 1 0.12 0 0 5.00
169 INT211716 Gene_expression of BAG1 2 0.52 0.92 0 5.00
170 INT179035 Gene_expression of Cdcs1 1 0.06 1.18 0 5.00
171 INT179040 Positive_regulation of Fez1 1 0.45 1.04 0 5.00
172 INT211715 Negative_regulation of Gene_expression of MSH6 1 0.06 1.09 0 5.00
173 INT339093 Positive_regulation of Gene_expression of Rcc1 1 0.02 1.21 0 5.00
174 INT251471 Gene_expression of LGALS13 1 0.10 1.02 0 5.00
175 INT179041 Positive_regulation of Cdcs1 1 0.04 0.64 0 5.00
176 INT339090 Positive_regulation of Ezh2 1 0.47 0.82 0 5.00
177 INT179042 Negative_regulation of Gene_expression of Fhit 1 0.45 4.21 0 5.00
178 INT251472 Positive_regulation of Gene_expression of LGALS13 1 0.08 0.48 0 5.00
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