D:Urticaria

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Disease Term
Synonyms Acute Urticaria, Angioneurotic Edema, Angioneurotic Oedema, CHRONIC URTICARIA, Giant Hives, Hives, Superficial Dermal Urticaria, Urticarias
Documents 1020
Hot Single Events 197
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Urticaria. They are ordered first by their relevance to Urticaria and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT133391 Positive_regulation of Binding of IGHE and IgG 1 0.03 2.88 0.27 99.90
2 INT133393 Binding of IGHE and IgG 1 0.03 2.86 0.27 99.58
3 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44 99.32
4 INT133392 Binding of SGCG and IgG 1 0.05 1.45 0.21 98.24
5 INT10739 IL3 Positive_regulation of CRP 1 0.18 1.14 0.09 97.76
6 INT10740 IL3 Positive_regulation of TNF 1 0.29 1.14 0.09 97.76
7 INT163918 Ntp Negative_regulation of Gene_expression of Tacr1 1 0.04 0.74 0.38 97.24
8 INT194537 Binding of PAEP and Uox 1 0.10 1.12 0.14 90.60
9 INT251864 Binding of HLA-DRB1 and IGHE 1 0.04 0.23 0 90.24
10 INT271000 Binding of HLA-DPB1 and Aia1 1 0.01 1.7 0.18 86.64
11 INT5217 Binding of GRDX and Tas2r124 1 0.11 0.37 0.05 83.60
12 INT5216 Binding of GRDX and Ighg3 1 0.42 0.37 0.05 83.60
13 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 82.88
14 INT270995 Binding of CYSLTR2 and OR6B1 1 0.01 2.14 0.15 80.68
15 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18 75.84
16 INT16444 IGHG3 Negative_regulation of Binding of IL1A 1 0.11 0.42 0.09 75.00
17 INT16442 Binding of IGHG3 and IL1A 1 0.10 0.36 0.05 75.00
18 INT252033 Binding of HLA-DQA2 and KLRD1 1 0.00 0.54 0.29 72.28
19 INT271003 Binding of TBXA2R and Aia1 1 0.01 1.81 0.14 71.20
20 INT304102 Il13 Positive_regulation of Gene_expression of IGHE 1 0.25 2.65 0.4 71.16
21 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 60.16
22 INT336835 Binding of CACNG6 and Aia1 1 0.01 3.41 0.75 56.24
23 INT304099 Binding of IGHE and Il13 1 0.17 4.13 0.38 55.56
24 INT304098 Binding of Il13 and Aia1 1 0.01 5.78 0.41 53.28
25 INT61824 Binding of SERPINH1 and CRP 1 0.24 0.63 0.08 50.88
26 INT327162 Binding of SERPING1 and F12 1 0.05 0.29 0.04 47.88
27 INT271002 Binding of LTC4S and Aia1 1 0.00 0.98 0.12 40.20
28 INT184192 IL1B Positive_regulation of SPAM1 1 0.04 0.49 0.24 30.08
29 INT194538 Binding of PAEP and Negative_regulation of Uox 1 0.13 0.31 0 23.88
30 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13 12.28
31 INT304094 Binding of AHR and SNRNP70 1 0.00 2.64 0.14 9.08
32 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
33 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
34 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
35 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
36 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
37 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
38 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 5.00
39 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 5.00
40 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 5.00
41 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
42 INT353741 Binding of IGHE and Aia1 1 0.00 1.16 1.06 5.00
43 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
44 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91 5.00
45 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
46 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78 5.00
47 INT209957 Binding of CD8A and RDBP Positive_regulation of CD8A 1 0.01 0.3 0.71 5.00
48 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 5.00
49 INT209956 Binding of CD8A and RDBP 1 0.01 0.3 0.7 5.00
50 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 5.00
51 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66 5.00
52 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66 5.00
53 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65 5.00
54 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 5.00
55 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 5.00
56 INT334500 Binding of IGHE and SPARCL1 1 0.01 1.47 0.55 5.00
57 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
58 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 5.00
59 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 5.00
60 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45 5.00
61 INT327090 Negative_regulation of F12 Negative_regulation of Gene_expression of KNG1 1 0.00 0.51 0.45 5.00
62 INT353730 Binding of FCGR2A and FCGR3A 1 0.33 0.5 0.41 5.00
63 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37 5.00
64 INT340850 Binding of IGHE and Baat 1 0.07 0.27 0.37 5.00
65 INT310934 Positive_regulation of Tgm2 Positive_regulation of Binding of IGHE 1 0.14 1.33 0.34 5.00
66 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
67 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
68 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
69 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
70 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
71 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 5.00
72 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
73 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
74 INT254287 Binding of TNFSF13B and TNFRSF13B 1 0.01 1.33 0.3 5.00
75 INT254288 Binding of ZNF623 and TNFSF13B 1 0.00 1.33 0.3 5.00
76 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29 5.00
77 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 5.00
78 INT279266 CADPS Positive_regulation of Regulation of IL1B 1 0.22 1.43 0.28 5.00
79 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26 5.00
80 INT177957 CCL11 Regulation of Binding of IL5 and CCL11 1 0.01 0.71 0.25 5.00
81 INT319229 Binding of SNRNP70 and Aia1 2 0.00 2.92 0.25 5.00
82 INT177960 Binding of IL5 and CCL11 1 0.03 0.71 0.25 5.00
83 INT320153 Negative_regulation of Binding of IL6 and IL6R 1 0.02 0.37 0.24 5.00
84 INT261842 Pla2g6 Positive_regulation of Trpm8 1 0.03 0 0.23 5.00
85 INT271001 Binding of PTGER2 and Aia1 1 0.00 1.28 0.23 5.00
86 INT184191 IL1B Positive_regulation of Gene_expression of SPAM1 1 0.03 0.59 0.23 5.00
87 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22 5.00
88 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
89 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
90 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21 5.00
91 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 5.00
92 INT177962 IL4 Positive_regulation of VCAM1 1 0.02 0.97 0.2 5.00
93 INT304104 Il13 Positive_regulation of Positive_regulation of AHR 1 0.14 2.6 0.19 5.00
94 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19 5.00
95 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19 5.00
96 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18 5.00
97 INT312819 IL5 Regulation of Il13 1 0.00 1.55 0.18 5.00
98 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
99 INT310932 Binding of Tgm2 and Serpinb1a 1 0.04 0.87 0.17 5.00
100 INT184194 Binding of HRAS and SPAM1 1 0.00 0.26 0.17 5.00
101 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
102 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16 5.00
103 INT269758 Negative_regulation of IGF1 Negative_regulation of Positive_regulation of IGFBP2 1 0.10 2.15 0.16 5.00
104 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15 5.00
105 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14 5.00
106 INT270996 TBXA2R Regulation of LTC4S 1 0.24 0.83 0.13 5.00
107 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
108 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11 5.00
109 INT319735 Positive_regulation of Binding of IL6 and IL8 1 0.01 1.35 0.11 5.00
110 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 5.00
111 INT199436 Binding of Capns1 and Cysltr1 1 0.00 0.79 0.1 5.00
112 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 5.00
113 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 5.00
114 INT353070 ADAM17 Positive_regulation of TNF 1 0.19 1.66 0.08 5.00
115 INT254286 Binding of TNFSF13B and TNFRSF13C 1 0.07 1.26 0.08 5.00
116 INT270682 Binding of OLR1 and RENBP 1 0.00 0.76 0.08 5.00
117 INT304100 Binding of CCL11 and Il13 1 0.05 0.86 0.08 5.00
118 INT310933 Il6 Positive_regulation of Tgm2 1 0.00 0.55 0.07 5.00
119 INT320160 Binding of FCER2 and IGHG3 1 0.00 0.35 0.06 5.00
120 INT320161 Binding of IGHE and IGHG3 1 0.02 0.35 0.06 5.00
121 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05 5.00
122 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05 5.00
123 INT304103 Il13 Positive_regulation of Gene_expression of CCL11 1 0.64 0.69 0.04 5.00
124 INT319973 App Regulation of Gene_expression of Mapk12 1 0.02 0.98 0.04 5.00
125 INT304101 Il13 Positive_regulation of CCL11 1 0.43 0.69 0.04 5.00
126 INT334497 Positive_regulation of IGHG3 Positive_regulation of IGHE 1 0.01 0.81 0.04 5.00
127 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 5.00
128 INT334496 IGHG3 Positive_regulation of IGHE 1 0.01 0.75 0.04 5.00
129 INT195195 IL4 Regulation of Gene_expression of IGHE 1 0.10 0.68 0.04 5.00
130 INT185756 Binding of ITIH4 and Cd4 2 0.05 1.22 0.04 5.00
131 INT269759 PTH Positive_regulation of DMD 2 0.06 0.37 0.03 5.00
132 INT311870 Positive_regulation of Binding of Cd8a and Mthfd1 1 0.00 0.32 0.03 5.00
133 INT274384 AGRP Negative_regulation of HIVEP1 1 0.00 0.77 0.03 5.00
134 INT351090 Phosphorylation of TXK Positive_regulation of EGFR 1 0.04 0.33 0 5.00
135 INT195199 Gene_expression of IL4 Positive_regulation of Gene_expression of IGHE 1 0.08 1.76 0 5.00
136 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
137 INT334498 Binding of IL13 and KLF1 1 0.00 0.63 0 5.00
138 INT195198 Gene_expression of IL5 Positive_regulation of Gene_expression of IGHE 1 0.09 1.76 0 5.00
139 INT270683 Binding of OXA1L and RENBP 1 0.00 0 0 5.00
140 INT195197 Gene_expression of IL9 Positive_regulation of Gene_expression of IGHE 1 0.05 1.77 0 5.00
141 INT195196 IL13 Positive_regulation of Gene_expression of IGHE 1 0.06 1.79 0 5.00
142 INT279268 CARD8 Positive_regulation of CASP1 1 0.32 0.3 0 5.00
143 INT294088 Binding of ERBB2 and ERBB4 2 0.13 0.88 0 5.00
144 INT261833 Binding of Add3 and Trpv4 1 0.00 0.12 0 5.00
145 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0 5.00
146 INT313572 GLP1R Negative_regulation of GCG 1 0.29 0.54 0 5.00
147 INT256400 GLP1R Positive_regulation of Localization of GCG 1 0.02 0.15 0 5.00
148 INT184196 GOPC Negative_regulation of HYAL1 1 0.02 0 0 5.00
149 INT239239 Binding of PPARA and RXRB 1 0.12 0.63 0 5.00
150 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0 5.00
151 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0 5.00
152 INT274385 Binding of ABAT and CDIPT 1 0.00 1.21 0 5.00
153 INT311816 CD79A Positive_regulation of RAB27A 1 0.01 0.47 0 5.00
154 INT255041 DPP4 Positive_regulation of GIP 1 0.49 0.32 0 5.00
155 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0 5.00
156 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0 5.00
157 INT184195 IL1B Regulation of Gene_expression of SPAM1 1 0.02 0 0 5.00
158 INT194516 UOX Positive_regulation of Gene_expression of PAEP 1 0.12 0.21 0 5.00
159 INT336836 Binding of RS1 and Aia1 1 0.00 0.33 0 5.00
160 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 5.00
161 INT255043 DPP4 Positive_regulation of GLP1R 1 0.35 0.32 0 5.00
162 INT195200 IL10 Positive_regulation of Gene_expression of IGHE 1 0.07 1.78 0 5.00
163 INT261844 Lyn Positive_regulation of Lyn Regulation of Trpv4 1 0.01 0.19 0 5.00
164 INT287268 Binding of ERBB2 and ERBB3 5 0.16 2.74 0 5.00
165 INT277766 EGFR Regulation of Gene_expression of VEGFA 1 0.54 0.14 0 5.00
166 INT306764 Binding of Aes and ZMYND10 1 0.04 0.21 0 5.00
167 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 5.00
168 INT194539 UOX Positive_regulation of Gene_expression of Uox 1 0.39 0.21 0 5.00
169 INT351085 Binding of EGFR and Positive_regulation of Phosphorylation of TXK 1 0.04 0.35 0 5.00
170 INT277772 Binding of EGFR and fc 1 0.01 0.57 0 5.00
171 INT304093 Binding of IL10 and TGFB1 1 0.02 1.21 0 5.00
172 INT255042 Negative_regulation of DPP4 Positive_regulation of GLP1R 1 0.33 0.34 0 5.00
173 INT336829 RS1 Regulation of CACNG6 1 0.15 0.15 0 5.00
174 INT261837 Binding of Aqp5 and Trpv4 1 0.05 0.17 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Urticaria. They are ordered first by their pain relevance and then by number of times they were reported in Urticaria. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT701 Localization of IGHE 87 0.80 40.5 10.62 100.00
2 INT122209 Positive_regulation of SIT1 1 0.50 0.57 0.13 100.00
3 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 100.00
4 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 100.00
5 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03 100.00
6 INT269370 Negative_regulation of Gene_expression of HSPG2 2 0.07 0.93 0.29 100.00
7 INT46384 Binding of TRGC1 16 0.41 4.87 1.28 99.98
8 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 99.96
9 INT817 Negative_regulation of Abp1 15 0.49 4.25 3.56 99.90
10 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59 99.84
11 INT74260 Positive_regulation of Serping1 5 0.64 6.05 0.8 99.84
12 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 99.84
13 INT15481 Positive_regulation of asa 13 0.39 6.12 8.24 99.82
14 INT50740 Positive_regulation of SPG21 18 0.67 8.3 1.65 99.74
15 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 99.66
16 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 99.64
17 INT21248 Localization of Lta 15 0.59 5.16 2.5 99.62
18 INT25022 Binding of PAEP 66 0.42 22.83 6.59 99.60
19 INT145384 Binding of LTA 10 0.32 4.4 0.66 99.52
20 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 99.34
21 INT4808 Gene_expression of LTC4S 37 0.73 18.36 9.62 99.32
22 INT135762 Binding of Ear1 2 0.41 1.6 0.18 99.30
23 INT117316 Positive_regulation of GZMA 3 0.59 3.11 0.15 99.28
24 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 99.26
25 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 99.16
26 INT245115 Positive_regulation of Gene_expression of ELF3 8 0.40 2.23 0.06 99.16
27 INT28424 Regulation of Cysltr1 17 0.41 7.33 6.34 99.12
28 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 99.00
29 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 98.90
30 INT213434 Gene_expression of HNMT 4 0.64 4.33 0.46 98.80
31 INT191288 Gene_expression of ABP1 7 0.52 6.61 0.4 98.80
32 INT304095 Binding of Aia1 2 0.03 3.93 1.5 98.80
33 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 98.64
34 INT271855 Gene_expression of PR@ 11 0.06 11.07 0.61 98.64
35 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 98.58
36 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 98.36
37 INT14600 Positive_regulation of Tpsab1 51 0.68 22.1 7.7 98.24
38 INT95917 Gene_expression of CYSLTR2 10 0.64 6.1 0.82 98.12
39 INT14103 Regulation of Hrh1 6 0.44 2.67 2.74 98.12
40 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 98.06
41 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 98.06
42 INT69160 Positive_regulation of IL5 41 0.65 36.04 7.75 98.06
43 INT78995 Negative_regulation of Agtr2 26 0.42 13.05 4.56 97.88
44 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43 97.64
45 INT288249 Localization of MS4A2 1 0.74 1.44 0.17 97.56
46 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 97.48
47 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 97.12
48 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68 97.12
49 INT63977 Positive_regulation of Sele 28 0.68 18.49 4.17 97.12
50 INT63979 Regulation of Sele 13 0.54 10.64 3.7 97.12
51 INT8775 Binding of IGHE 167 0.48 102.61 23.54 97.08
52 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 97.04
53 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 97.02
54 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52 96.88
55 INT18843 Binding of H1 10 0.47 5.44 2.4 96.76
56 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14 96.72
57 INT193251 Binding of CYSLTR1 13 0.32 8.32 2.57 96.64
58 INT171832 Positive_regulation of Nrl 2 0.43 1.7 0 96.56
59 INT37076 Negative_regulation of Binding of KNG1 3 0.14 1.77 1.32 96.48
60 INT54701 Localization of Ptafr 19 0.49 18.68 3.82 96.44
61 INT27758 Positive_regulation of PTGDS 20 0.67 10.74 4.22 96.44
62 INT60423 Positive_regulation of TPSG1 11 0.57 11.02 2.55 96.32
63 INT23178 Gene_expression of H1 38 0.68 13.37 9.09 96.24
64 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 96.24
65 INT66792 Binding of TPSAB1 7 0.16 4.93 1.45 96.00
66 INT15186 Negative_regulation of HRH2 8 0.51 2.26 0.99 96.00
67 INT100861 Binding of CRP 179 0.48 175.2 26.45 95.84
68 INT20462 Binding of ESR1 210 0.44 102.7 26.34 95.84
69 INT3167 Binding of KNG1 48 0.48 23.26 26.77 95.44
70 INT7743 Binding of Hrh2 19 0.47 7.75 7.11 95.24
71 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 95.16
72 INT35866 Transcription of IGHE 9 0.60 12.83 2.19 95.16
73 INT21840 Positive_regulation of IL3 20 0.70 14.44 2.86 94.84
74 INT25503 Gene_expression of C5AR1 22 0.75 21.88 4.16 94.64
75 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 94.52
76 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 94.44
77 INT326468 Regulation of Negative_regulation of TRGC1 1 0.19 2.8 0.17 94.44
78 INT94026 Regulation of SERPING1 12 0.61 10.28 0.37 94.32
79 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19 94.20
80 INT16446 Transcription of IL1A 4 0.69 1.76 0.96 94.20
81 INT1283 Positive_regulation of CD79B 1 0.67 0.69 0.14 94.00
82 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 93.92
83 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 93.92
84 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 93.92
85 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78 93.92
86 INT5789 Gene_expression of PMEL 23 0.75 13.18 2.67 93.92
87 INT22004 Positive_regulation of Binding of IGHE 7 0.49 3.29 0.96 93.80
88 INT169525 Positive_regulation of Serpinb1a 4 0.44 6.48 1.24 93.56
89 INT194530 Gene_expression of UOX 17 0.65 11.78 0.17 93.36
90 INT194533 Binding of UOX 2 0.47 3.86 0.2 93.36
91 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 93.28
92 INT23620 Negative_regulation of C4A 24 0.57 15.1 2.23 93.28
93 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 93.04
94 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 92.92
95 INT9210 Regulation of IL6 166 0.62 125.61 49.95 92.92
96 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 92.92
97 INT244159 Transcription of NLRP3 3 0.64 5.61 0.39 92.88
98 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 92.88
99 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 92.88
100 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 92.88
101 INT80656 Regulation of SLC17A5 15 0.26 6.89 3.19 92.88
102 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17 92.84
103 INT62044 Binding of Lta 16 0.30 7.49 1.01 92.56
104 INT25130 Positive_regulation of Negative_regulation of Ptgs1 14 0.50 5.07 6.29 92.40
105 INT19430 Positive_regulation of IGHA1 10 0.67 6.42 2.58 92.40
106 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 92.12
107 INT14598 Gene_expression of Tpsab1 40 0.73 14.55 5.4 92.00
108 INT313894 Transcription of CADPS 1 0.44 2.72 0.19 91.64
109 INT64676 Gene_expression of ANXA5 11 0.75 13.48 2.11 91.52
110 INT127607 Gene_expression of EID1 4 0.63 5.57 1.6 91.52
111 INT14572 Binding of INS 205 0.48 175.43 13.38 91.28
112 INT181525 Localization of Il13 24 0.66 21.51 6.55 91.16
113 INT5298 Negative_regulation of MTHFS 70 0.57 27.07 28.11 91.00
114 INT14599 Localization of Tpsab1 36 0.79 14.58 7.18 90.88
115 INT26239 Positive_regulation of Gene_expression of Lta 12 0.36 8.86 4.22 90.60
116 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 90.60
117 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 90.04
118 INT328286 Positive_regulation of C1orf38 1 0.01 2.93 0.33 90.00
119 INT105216 Positive_regulation of Trpv2 9 0.61 4.12 4.93 89.80
120 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 89.80
121 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 88.96
122 INT6852 Localization of TNF 883 0.81 705.95 270.84 88.64
123 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 88.48
124 INT143621 Negative_regulation of Negative_regulation of TPSG1 1 0.00 0.65 0.26 88.44
125 INT143622 Negative_regulation of TPSG1 2 0.41 1.8 0.26 88.44
126 INT115370 Gene_expression of PSIP1 22 0.65 9.45 5.68 88.32
127 INT183979 Localization of PSIP1 2 0.73 1.37 0.59 88.32
128 INT19134 Gene_expression of TPSAB1 16 0.66 11.61 2.48 88.24
129 INT74777 Positive_regulation of Gene_expression of TPSAB1 4 0.50 3.7 0.92 88.24
130 INT310935 Negative_regulation of Gene_expression of TPSAB1 1 0.13 1.08 0 88.24
131 INT6481 Binding of TNF 624 0.48 510.2 214.82 88.16
132 INT39417 Gene_expression of Fcer2a 65 0.76 32.1 7.37 88.16
133 INT72890 Positive_regulation of Gene_expression of Fcer2a 12 0.17 6.81 2.25 88.16
134 INT67183 Binding of Serpinb1a 4 0.37 4 1.77 88.08
135 INT3034 Localization of Ngf 126 0.81 50.81 72.84 88.08
136 INT75997 Positive_regulation of Localization of Ngf 14 0.69 7.78 9.41 88.08
137 INT14477 Positive_regulation of TPSAB1 10 0.69 5.88 1.46 87.68
138 INT62800 Regulation of BAK1 7 0.41 10.12 1.47 87.52
139 INT334504 Regulation of Transcription of IGHE 1 0.29 7.97 0.57 87.44
140 INT158998 Negative_regulation of PTPLA 4 0.41 4.33 0 87.36
141 INT270999 Positive_regulation of Gene_expression of CYSLTR2 1 0.44 2.81 0.27 87.28
142 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 87.12
143 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82 87.12
144 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25 87.12
145 INT32130 Gene_expression of TPSG1 12 0.51 6.59 1.88 87.04
146 INT13634 Gene_expression of CYSLTR1 19 0.75 11.24 2.88 86.88
147 INT156672 Localization of SERPING1 10 0.74 12.15 1.25 86.80
148 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 86.52
149 INT125711 Negative_regulation of TSS 6 0.51 3.64 0.12 86.24
150 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 86.08
151 INT7134 Localization of KNG1 127 0.79 65.73 67.97 86.08
152 INT9660 Regulation of TNF 363 0.62 312.94 139.99 85.92
153 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 85.72
154 INT279225 Positive_regulation of Gene_expression of UOX 1 0.02 0.52 0 85.72
155 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 85.60
156 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 85.44
157 INT39866 Gene_expression of RUNX1T1 2 0.65 1.75 0.1 85.00
158 INT158999 Gene_expression of VN1R7P 1 0.00 1.06 0.08 84.92
159 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 84.84
160 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41 84.64
161 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 84.60
162 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 84.56
163 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 84.56
164 INT159000 Gene_expression of OR4R3P 1 0.00 1.06 0.08 84.52
165 INT57780 Gene_expression of RNASE2 1 0.03 1.49 0.13 84.48
166 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 84.44
167 INT17442 Gene_expression of ALOX5 110 0.75 51.55 18.29 84.44
168 INT5215 Gene_expression of GRDX 2 0.75 1.7 0.05 84.40
169 INT96092 Binding of ANXA5 24 0.36 14.51 2.6 84.40
170 INT269716 Binding of HPD 3 0.31 1.42 0.08 84.24
171 INT35359 Negative_regulation of LCT 23 0.59 9.13 2.29 84.16
172 INT158997 Gene_expression of RPL4P4 1 0.01 1 0.08 83.96
173 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 83.84
174 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 83.36
175 INT152720 Localization of Trpv2 6 0.69 2.71 1.54 82.88
176 INT3811 Negative_regulation of PAEP 36 0.50 23.7 5.18 82.48
177 INT185738 Binding of Cd14 28 0.45 14.41 3.25 82.40
178 INT194521 Negative_regulation of Uox 7 0.52 4.93 0.41 82.32
179 INT234422 Gene_expression of PML 14 0.75 15.93 1.14 82.28
180 INT20228 Negative_regulation of Gene_expression of Lta 8 0.22 3.81 1.03 82.08
181 INT70049 Positive_regulation of Gene_expression of LTA 7 0.32 4.66 3.25 82.08
182 INT67594 Protein_catabolism of Abp1 1 0.23 0.99 0.12 82.00
183 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 81.92
184 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11 81.76
185 INT13539 Gene_expression of LTA 39 0.62 22.55 8.07 81.72
186 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 81.68
187 INT109097 Positive_regulation of Gene_expression of GGT5 2 0.05 2.19 0.24 81.64
188 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 81.60
189 INT107385 Regulation of Negative_regulation of AGTR1 2 0.15 1.26 0.42 81.60
190 INT19044 Positive_regulation of GGT5 10 0.65 7.7 1.11 81.56
191 INT87211 Positive_regulation of Localization of Nfkb1 27 0.59 15.84 5.25 81.36
192 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94 81.36
193 INT25607 Binding of Il1 82 0.47 64.4 23.9 81.32
194 INT19188 Binding of Igh-6 11 0.48 2.97 4.88 80.96
195 INT273471 Negative_regulation of PTBP1 7 0.34 9.2 1.1 80.72
196 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 80.32
197 INT84946 Gene_expression of GGT5 5 0.06 2.31 0.31 80.24
198 INT195 Gene_expression of C4a 16 0.48 15.55 6.1 80.00
199 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 79.96
200 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 79.80
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