D:Variegate Porphyria

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pChart

Disease Term
Synonyms DEFICIENCIES PROTOPORPHYRINOGEN OXIDASE, Protoporphyrinogen Oxidase Deficiency
Documents 27
Hot Single Events 21
Hot Interactions 0

Single Events

The table below shows the top 200 pain related interactions that have been reported for Variegate Porphyria. They are ordered first by their pain relevance and then by number of times they were reported in Variegate Porphyria. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT196375 Negative_regulation of Ppox 2 0.08 2.73 0 99.96
2 INT158690 Negative_regulation of 3.8-1.4 2 0.07 2.77 0.13 99.96
3 INT62689 Negative_regulation of PPOX 7 0.58 4.66 0.28 99.60
4 INT62690 Gene_expression of PPOX 7 0.77 3.3 0.13 99.20
5 INT50291 Positive_regulation of HMBS 10 0.67 8.89 0.73 99.20
6 INT63178 Positive_regulation of Rhox10 1 0.01 0.74 0.25 99.08
7 INT239435 Regulation of PPOX 1 0.18 0.26 0 98.76
8 INT40216 Positive_regulation of Alas1 11 0.65 6.08 1.8 97.24
9 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 96.88
10 INT8047 Positive_regulation of Nts 20 0.67 7.96 10.35 96.88
11 INT8724 Positive_regulation of Mln 21 0.66 14.12 6.17 96.88
12 INT22591 Negative_regulation of Hmbs 6 0.51 5.04 1.74 95.92
13 INT239436 Localization of PPOX 3 0.54 0.67 0 95.20
14 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 95.00
15 INT120656 Localization of HMBS 3 0.16 2.6 0.23 94.52
16 INT239437 Transcription of PPOX 1 0.42 0.62 0 93.12
17 INT40215 Negative_regulation of Fech 9 0.57 8.39 1.85 90.16
18 INT22592 Positive_regulation of Hmbs 2 0.48 2.27 0.87 86.80
19 INT196373 Negative_regulation of Vmn2r81 1 0.02 1.96 0 86.16
20 INT151791 Binding of Ppox 2 0.14 0.57 0 85.24
21 INT35990 Negative_regulation of Sds 8 0.49 4.47 4.96 85.12
22 INT50290 Binding of Cpox 29 0.27 17.19 8.01 66.80
23 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06 47.04
24 INT196372 Positive_regulation of Alas1 1 0.19 1.91 0.22 42.68
25 INT127038 Gene_expression of Alas1 6 0.72 3.94 1.48 34.28
26 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 34.08
27 INT196374 Negative_regulation of Positive_regulation of Alas1 1 0.16 0.67 0.12 21.00
28 INT127040 Negative_regulation of Alas1 2 0.35 0.72 0.54 16.32
29 INT196376 Positive_regulation of Gene_expression of Alas1 1 0.19 1.01 0.25 8.80
30 INT196377 Gene_expression of Nrf1 4 0.68 5.97 2.63 6.32
31 INT84130 Gene_expression of Foxo1 1 0.26 0.97 1.22 6.32
32 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 5.00
33 INT102746 Negative_regulation of Hmbs 11 0.59 8.35 0.77 5.00
34 INT196371 Gene_expression of Ireb2 1 0.41 1.95 0 5.00
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