D:Vascular Dementia

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Disease Term
Synonyms Acute Onset Vascular Dementia, Arteriosclerotic Dementia, Arteriosclerotic Dementias, Arteriosclerotic Encephalopathies Subcortical, Arteriosclerotic Encephalopathy Subcortical, BINSWANGER DISEASE, Binswanger Encephalopathy, Binswanger S Encephalopathy, CHRONIC PROGRESSIVE SUBCORTICAL ENCEPHALOPATHY, Dementia Arteriosclerotic, Dementia Subcortical Vascular
Documents 171
Hot Single Events 104
Hot Interactions 11

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Vascular Dementia. They are ordered first by their relevance to Vascular Dementia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT308648 Binding of sps and Gopc 1 0.01 2.71 0 100.00
2 INT325429 Mapt Positive_regulation of Csf2 1 0.13 1.29 0 98.48
3 INT308643 Binding of Proc and Renbp 1 0.00 1.61 0 98.28
4 INT161086 NOTCH3 Regulation of Notch3 1 0.51 1.06 0.14 87.68
5 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13 82.56
6 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13 82.40
7 INT325431 Positive_regulation of Binding of Csf2 and Mapt 1 0.18 1.49 0 81.96
8 INT312550 DAK Positive_regulation of Rxra 1 0.00 1.48 0.18 81.72
9 INT312519 DAK Positive_regulation of PPARA 1 0.00 1.46 0.18 81.72
10 INT325433 Binding of Csf2 and Mapt 1 0.12 4.41 0 81.56
11 INT273047 Binding of Aqp4 and Sct 1 0.04 1.41 0 80.16
12 INT209400 Binding of F13A1 and FGG 1 0.01 1.72 0.09 78.24
13 INT337118 MCRS1 Negative_regulation of C7orf49 1 0.00 0.66 0.04 75.76
14 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 75.68
15 INT325428 Csf2 Regulation of Mapt 1 0.08 1.47 0 73.92
16 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29 71.36
17 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29 71.36
18 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29 71.04
19 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29 71.04
20 INT312547 Akt1 Positive_regulation of Phosphorylation of Ide 1 0.01 0.6 0.08 60.80
21 INT325432 Vsnl1 Positive_regulation of Csf2 1 0.19 1.07 0 54.96
22 INT325430 Vsnl1 Positive_regulation of Vhl-ps1 1 0.03 1.01 0 54.08
23 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46 43.72
24 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51 33.00
25 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36 27.80
26 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19 27.80
27 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21 16.76
28 INT340742 Positive_regulation of CSF2 Regulation of BDNF 1 0.22 1.46 0.14 12.12
29 INT340744 CSF2 Regulation of BDNF 1 0.13 1.45 0.14 11.76
30 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
31 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
32 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 5.00
33 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
34 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69 5.00
35 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65 5.00
36 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58 5.00
37 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5 5.00
38 INT298999 Binding of Il18bp and Il18 1 0.02 0 0.45 5.00
39 INT316063 Ps Positive_regulation of IL8 1 0.09 1.33 0.41 5.00
40 INT316065 Eif1 Positive_regulation of IL8 1 0.01 1.34 0.41 5.00
41 INT273045 Vip Regulation of Adcyap1 1 0.17 0.5 0.38 5.00
42 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36 5.00
43 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36 5.00
44 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35 5.00
45 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34 5.00
46 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34 5.00
47 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34 5.00
48 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34 5.00
49 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34 5.00
50 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34 5.00
51 INT298472 LPA Positive_regulation of Gene_expression of CXCL16 1 0.05 0.41 0.32 5.00
52 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32 5.00
53 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 5.00
54 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29 5.00
55 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25 5.00
56 INT299013 Il18 Regulation of Ltp 1 0.05 0.39 0.25 5.00
57 INT312546 Ros1 Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.87 0.25 5.00
58 INT298993 Il2 Positive_regulation of Gene_expression of Il13 1 0.01 0.73 0.24 5.00
59 INT299003 Il18 Positive_regulation of Gene_expression of Il13 1 0.11 0.73 0.24 5.00
60 INT308670 Positive_regulation of CYBB Positive_regulation of Gene_expression of Ros1 1 0.00 0.68 0.23 5.00
61 INT328228 Binding of Cpox and Hmox1 1 0.03 0.83 0.23 5.00
62 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 5.00
63 INT308650 Binding of nt and Ntrk2 1 0.01 0.41 0.21 5.00
64 INT316054 Eif1 Positive_regulation of Il6 1 0.00 0.78 0.21 5.00
65 INT316062 Ps Positive_regulation of Il6 1 0.04 0.77 0.21 5.00
66 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21 5.00
67 INT308654 Binding of Ngfr and Nts 1 0.06 0.39 0.21 5.00
68 INT299000 Positive_regulation of Il18 Regulation of Ltp 1 0.05 0.35 0.2 5.00
69 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2 5.00
70 INT316064 Binding of RBPJ and Csl 1 0.16 0.33 0.2 5.00
71 INT308646 Car2 Regulation of Gene_expression of Ins1 1 0.00 0 0.19 5.00
72 INT308669 CREB1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19 5.00
73 INT308657 Creb1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19 5.00
74 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18 5.00
75 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17 5.00
76 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17 5.00
77 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15 5.00
78 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 0.00 0.48 0.15 5.00
79 INT298475 LPA Positive_regulation of Gene_expression of IL8 1 0.07 0.38 0.15 5.00
80 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15 5.00
81 INT298500 Alb Positive_regulation of Paf 1 0.01 0.34 0.15 5.00
82 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15 5.00
83 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15 5.00
84 INT299012 Binding of Il18bp and Il1f5 1 0.00 0 0.14 5.00
85 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
86 INT257937 Binding of CSF2 and INVS 1 0.04 1.1 0.14 5.00
87 INT316059 Ps Regulation of Binding of Cd4 1 0.06 0.86 0.13 5.00
88 INT316058 Ps Regulation of Binding of Cd8a 1 0.02 0.86 0.13 5.00
89 INT308659 Binding of Ager and ecs 1 0.01 1.14 0.12 5.00
90 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 5.00
91 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12 5.00
92 INT298479 CD40LG Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.00 0.33 0.12 5.00
93 INT298474 IL4 Positive_regulation of HLA-DRB1 1 0.02 0.33 0.12 5.00
94 INT308647 Ager Positive_regulation of Gene_expression of Bace1 1 0.09 1.01 0.12 5.00
95 INT298478 IL4 Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 5.00
96 INT298473 IL4 Positive_regulation of CD80 1 0.06 0.33 0.12 5.00
97 INT308660 Binding of Ager and App 1 0.08 1.22 0.12 5.00
98 INT308651 Binding of Igf1 and Ins1 1 0.02 0.22 0.11 5.00
99 INT299015 Binding of FAS and Il18 1 0.38 0.83 0.11 5.00
100 INT298497 CTSC Positive_regulation of F10 Positive_regulation of F2 1 0.00 0.12 0.1 5.00
101 INT298994 Binding of Il18 and Il1f5 1 0.01 0 0.1 5.00
102 INT264085 CYP2C19 Regulation of CYP3A4 1 0.02 0 0.09 5.00
103 INT264103 Cyp2e1 Regulation of CYP2C9 1 0.04 0 0.09 5.00
104 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09 5.00
105 INT308662 Binding of Esr1 and Fdft1 1 0.00 0.05 0.09 5.00
106 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09 5.00
107 INT264083 CYP2C19 Regulation of CYP2D6 1 0.05 0 0.09 5.00
108 INT298502 F10 Positive_regulation of F2 1 0.00 0.12 0.09 5.00
109 INT264084 CYP2C19 Regulation of CYP2C9 1 0.03 0 0.09 5.00
110 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09 5.00
111 INT308666 Binding of Lrp1 and Chol1 1 0.10 0.69 0.09 5.00
112 INT264107 Cyp2e1 Regulation of CYP2D6 1 0.05 0 0.09 5.00
113 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09 5.00
114 INT308652 Binding of Renbp and Nps 1 0.01 1.38 0.09 5.00
115 INT299002 Negative_regulation of Binding of Il18bp and Il18 1 0.02 0 0.08 5.00
116 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07 5.00
117 INT308655 Binding of Lrp1 and Gopc 1 0.01 0.49 0.07 5.00
118 INT299009 Il1f5 Negative_regulation of Il18 1 0.01 0 0.07 5.00
119 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07 5.00
120 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07 5.00
121 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06 5.00
122 INT288099 Binding of APP and App 1 0.01 1.04 0.05 5.00
123 INT308649 Binding of Ppp1r13b and Iars 1 0.01 0.29 0.04 5.00
124 INT316060 Binding of Erbb4 and Ncor2 1 0.12 0.41 0.03 5.00
125 INT316061 Positive_regulation of Binding of Erbb4 and Nrg1 1 0.03 0.38 0.03 5.00
126 INT316057 Binding of Erbb4 and Nrg1 2 0.03 0.38 0.03 5.00
127 INT316056 Binding of Ncor2 and Tab2 1 0.12 0.41 0.03 5.00
128 INT270432 Lhb Positive_regulation of APP 1 0.03 0.51 0.03 5.00
129 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03 5.00
130 INT316055 Binding of Erbb4 and Tab2 1 0.23 0.4 0.03 5.00
131 INT270431 Gnrh1 Positive_regulation of APP 1 0.06 0.51 0.03 5.00
132 INT299006 Binding of Il18 and Myd88 1 0.21 0.19 0.03 5.00
133 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
134 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0 5.00
135 INT340743 Negative_regulation of CSF2 Positive_regulation of ZNF807 1 0.00 1.77 0 5.00
136 INT340745 CSF2 Positive_regulation of ZNF807 1 0.00 1.76 0 5.00
137 INT308664 Akt1 Positive_regulation of Phosphorylation of Insr 1 0.02 0.43 0 5.00
138 INT273287 Binding of Atp2a2 and Pln 1 0.08 0.26 0 5.00
139 INT273290 Binding of Atp2a2 and Tlx2 1 0.05 0.26 0 5.00
140 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0 5.00
141 INT273291 Atp2a2 Regulation of Car2 1 0.10 0.31 0 5.00
142 INT273286 Tlx2 Regulation of Car2 1 0.06 0.31 0 5.00
143 INT121225 Positive_regulation of Ngf Positive_regulation of Ntrk1 2 0.49 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Vascular Dementia. They are ordered first by their pain relevance and then by number of times they were reported in Vascular Dementia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT241191 Positive_regulation of Kctd1 2 0.06 4.28 0.16 100.00
2 INT267653 Gene_expression of Kctd1 3 0.09 3.56 0.16 100.00
3 INT272837 Phosphorylation of Kctd1 1 0.11 1.56 0.07 100.00
4 INT109613 Regulation of Kctd1 3 0.23 1.59 0.37 100.00
5 INT105722 Binding of Kctd1 4 0.35 4.4 0.43 100.00
6 INT81043 Negative_regulation of Kctd1 9 0.57 7.68 1.06 100.00
7 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 100.00
8 INT203311 Positive_regulation of Gene_expression of Igfals 5 0.16 6.87 0.8 100.00
9 INT225227 Gene_expression of NF2 4 0.65 4.49 0.03 99.96
10 INT164205 Binding of Proc 12 0.36 12.31 1.19 99.48
11 INT101450 Positive_regulation of DLEU1 2 0.22 2.65 0.12 99.32
12 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3 99.12
13 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48 99.12
14 INT20205 Binding of IgG 108 0.46 66.68 8.57 99.08
15 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.04
16 INT106745 Localization of CRP 65 0.81 66.44 15.21 99.04
17 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 98.88
18 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 98.84
19 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 98.84
20 INT324672 Negative_regulation of Gene_expression of CEBPZ 2 0.36 2.75 0.48 98.64
21 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 98.48
22 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 98.44
23 INT16395 Gene_expression of CEBPZ 30 0.57 11.02 6.66 98.42
24 INT263689 Positive_regulation of Mapt 6 0.49 5.15 0.36 98.20
25 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 98.00
26 INT259536 Transcription of Psd 2 0.38 1.25 0.16 97.64
27 INT9660 Regulation of TNF 363 0.62 312.94 139.99 96.84
28 INT100655 Regulation of BDNF 51 0.60 21.49 13.14 96.84
29 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 96.64
30 INT144273 Negative_regulation of Binding of Bche 2 0.59 2.21 0.89 96.64
31 INT80597 Negative_regulation of Ptcra 4 0.37 2.54 1.01 96.64
32 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 96.56
33 INT166776 Localization of HMGN4 2 0.32 1.14 0.12 96.16
34 INT10694 Binding of Bche 19 0.48 8.03 4.85 96.12
35 INT48390 Negative_regulation of Localization of CSF2 10 0.51 7.39 3.28 95.96
36 INT169628 Binding of SNCA 4 0.47 3.53 0.36 95.92
37 INT58581 Binding of RPA1 8 0.44 1.68 1.44 95.92
38 INT14690 Localization of CSF2 124 0.80 85.17 27.26 95.72
39 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 95.32
40 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 95.16
41 INT17295 Regulation of Gene_expression of CEBPZ 2 0.33 0.57 0.04 94.72
42 INT200206 Negative_regulation of Gene_expression of Igfals 4 0.21 3.83 0.5 94.52
43 INT3463 Gene_expression of Igfals 21 0.39 21.1 2.93 94.30
44 INT50080 Binding of APOE 38 0.45 29.61 2.67 93.40
45 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 93.40
46 INT210522 Protein_catabolism of Ide 16 0.79 7.73 0.55 93.04
47 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 92.64
48 INT204124 Transcription of CRP 14 0.69 20.79 2.71 92.24
49 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73 92.16
50 INT170554 Binding of Renbp 17 0.17 12.36 0.45 91.76
51 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 91.68
52 INT33735 Binding of ANGPTL5 39 0.32 14.23 3.66 91.64
53 INT166777 Regulation of HMGN4 1 0.19 1.01 0.14 91.60
54 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 91.20
55 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 90.88
56 INT15310 Gene_expression of DLEU1 8 0.67 20.57 0.96 90.40
57 INT63133 Gene_expression of Pd 13 0.18 5.31 0.61 90.40
58 INT111820 Positive_regulation of Fdps 10 0.42 10.63 3.01 90.16
59 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 90.00
60 INT97254 Positive_regulation of Gap43 22 0.46 7.36 4.48 89.88
61 INT207165 Gene_expression of DAK 18 0.08 9.41 2.69 89.44
62 INT14301 Binding of CSF2 82 0.48 67.95 8.98 89.28
63 INT252286 Phosphorylation of Il18 2 0.79 2.22 0.86 89.20
64 INT209405 Regulation of Binding of CSF2 2 0.28 1.17 0.04 89.08
65 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 88.12
66 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 87.84
67 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 87.60
68 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68 87.60
69 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 87.48
70 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 87.36
71 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 87.36
72 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96 87.36
73 INT213154 Positive_regulation of Binding of TIMP1 2 0.41 1.33 0.55 87.36
74 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72 87.16
75 INT106952 Positive_regulation of NPC1 23 0.43 22.9 0.94 86.92
76 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 86.80
77 INT1114 Localization of Ins1 748 0.80 192.95 165.48 86.24
78 INT100861 Binding of CRP 179 0.48 175.2 26.45 86.12
79 INT209403 Positive_regulation of MYL10 1 0.01 6.28 0.07 86.04
80 INT15148 Gene_expression of Vip 51 0.77 25.61 18.33 85.68
81 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14 85.68
82 INT337121 Negative_regulation of Regulation of CEBPZ 1 0.31 0.81 0.15 85.56
83 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 85.56
84 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 85.56
85 INT242259 Negative_regulation of Positive_regulation of CEBPZ 4 0.48 1.44 0.59 85.56
86 INT242260 Regulation of Positive_regulation of CEBPZ 2 0.35 0.55 0.07 85.56
87 INT340751 Binding of DLEU1 1 0.20 12.05 0.49 85.08
88 INT36678 Binding of TIMP1 33 0.36 14.99 7.87 84.88
89 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52 84.60
90 INT107068 Negative_regulation of BACE1 5 0.42 1.81 2.2 84.60
91 INT15149 Positive_regulation of Gene_expression of Vip 2 0.44 3.53 1.25 83.12
92 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22 83.12
93 INT139982 Positive_regulation of BACE2 6 0.42 4.33 1.48 83.04
94 INT8757 Binding of ACHE 10 0.48 5.84 1.72 82.92
95 INT137795 Positive_regulation of BACE1 3 0.68 4.74 4.31 82.76
96 INT315626 Localization of DLEU1 2 0.35 4.17 0.07 82.72
97 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 81.80
98 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 81.80
99 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 81.40
100 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 81.40
101 INT23775 Regulation of S100B 24 0.62 16.75 2.57 81.36
102 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77 81.36
103 INT145929 Regulation of Bax 20 0.60 18.12 5.35 80.36
104 INT134443 Binding of Bax 10 0.47 5.62 1.84 80.36
105 INT167182 Binding of Psd 9 0.41 13.08 1.06 79.88
106 INT4012 Negative_regulation of Psd 23 0.52 14.12 3.81 79.84
107 INT101726 Gene_expression of Notch3 4 0.77 4.87 0.64 79.68
108 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 78.80
109 INT75627 Gene_expression of Mapt 41 0.75 22.1 4.58 78.44
110 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 78.40
111 INT161085 Positive_regulation of Notch3 4 0.41 4.36 0.27 78.28
112 INT261215 Localization of Sct 2 0.44 1.01 0.17 77.76
113 INT219329 Transcription of NOTCH3 1 0.69 0.48 0.03 77.60
114 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68 77.36
115 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 77.04
116 INT136921 Gene_expression of NOTCH3 5 0.67 4.27 0.16 76.96
117 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 76.44
118 INT270425 Binding of NEGR1 1 0.04 0.94 0.09 76.16
119 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 76.08
120 INT169862 Regulation of NPC1 13 0.53 13.61 1.84 75.76
121 INT2910 Regulation of Abat 169 0.62 36.95 153.53 75.44
122 INT334212 Negative_regulation of DLEU1 2 0.28 8.84 0.53 75.00
123 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 74.88
124 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 74.56
125 INT6666 Negative_regulation of PENK 30 0.58 9.16 17.91 74.40
126 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 74.16
127 INT21833 Positive_regulation of C1QL1 4 0.67 3.39 2.15 74.16
128 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84 74.00
129 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 74.00
130 INT111047 Negative_regulation of Gene_expression of Aqp2 3 0.34 3.56 0.09 73.08
131 INT39374 Gene_expression of Sct 5 0.68 1.42 3.89 72.92
132 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 72.64
133 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 72.64
134 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23 72.52
135 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03 71.68
136 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2 71.36
137 INT298974 Transcription of Cdk5r1 1 0.04 1.64 0.28 71.36
138 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64 71.12
139 INT99538 Gene_expression of Slc1a1 26 0.75 9.3 21.57 71.08
140 INT298972 Transcription of Cdk5 1 0.15 1.63 0.28 71.04
141 INT175580 Localization of APOE 10 0.76 18.84 0.65 70.24
142 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92 70.00
143 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 69.48
144 INT2570 Negative_regulation of Gene_expression of Ache 13 0.43 2.88 2.18 69.48
145 INT118005 Regulation of Apoc4 2 0.02 1.42 0.89 69.20
146 INT169318 Positive_regulation of Rxra 15 0.42 4.35 2.12 69.08
147 INT337123 Phosphorylation of CEBPZ 1 0.59 0.64 0.04 68.80
148 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73 68.60
149 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 68.36
150 INT126751 Regulation of Gene_expression of IL10 16 0.44 10.84 5.22 68.36
151 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1 68.36
152 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 67.48
153 INT76467 Regulation of Gene_expression of Car2 41 0.37 12.88 4.21 67.48
154 INT17561 Localization of Car2 303 0.79 60.95 44.52 67.48
155 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 67.40
156 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 67.40
157 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 65.80
158 INT272256 Protein_catabolism of Psd 3 0.49 2.66 0.19 64.64
159 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 63.44
160 INT304218 Regulation of skt 1 0.03 0.73 0 63.24
161 INT123752 Regulation of Bax 19 0.60 16.45 4 63.12
162 INT25989 Localization of Vip 31 0.68 10.53 10.35 62.92
163 INT264054 Negative_regulation of Negative_regulation of Bche 6 0.41 2.49 0.04 62.72
164 INT326522 Positive_regulation of Gene_expression of HGS 1 0.07 2.62 0.08 61.00
165 INT139896 Phosphorylation of Ins1 29 0.77 24.03 2.35 60.60
166 INT136927 Gene_expression of HGS 18 0.70 14.42 0.6 60.56
167 INT326523 Negative_regulation of Gene_expression of HGS 1 0.06 2.64 0.08 60.56
168 INT286615 Phosphorylation of Ide 7 0.31 5.22 0.7 60.48
169 INT176242 Binding of Bax 10 0.42 10.18 0.52 60.40
170 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 60.32
171 INT32826 Positive_regulation of Gene_expression of Ltp 52 0.45 10.34 26.8 59.84
172 INT54466 Negative_regulation of Gene_expression of Ltp 19 0.38 5.44 10.91 59.48
173 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 59.48
174 INT334211 Positive_regulation of Gene_expression of TARDBP 1 0.32 3.03 0 59.40
175 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 58.96
176 INT264685 Gene_expression of TARDBP 4 0.61 8.8 0.31 58.84
177 INT334213 Transcription of TARDBP 1 0.24 0.98 0 58.84
178 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 58.56
179 INT2578 Binding of Ins1 74 0.48 33.57 12.92 58.36
180 INT183761 Phosphorylation of Csf2 6 0.80 4.04 1.58 58.24
181 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 57.80
182 INT40771 Positive_regulation of Iars 6 0.36 2.1 1.33 57.76
183 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 57.40
184 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 57.40
185 INT273454 Gene_expression of Fat1 21 0.76 6.6 0.18 57.36
186 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 57.12
187 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 56.92
188 INT209407 Positive_regulation of FGG 1 0.24 1.59 0.03 56.84
189 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06 56.56
190 INT6063 Positive_regulation of Bche 17 0.66 6.07 3.08 56.40
191 INT272956 Positive_regulation of Binding of Psd 1 0.28 2.66 0 56.16
192 INT97216 Positive_regulation of Psd 13 0.45 7.04 1.25 55.44
193 INT179693 Positive_regulation of DAK 14 0.04 6.02 1.4 54.80
194 INT210533 Negative_regulation of Binding of Ide 3 0.25 1.93 0.16 53.84
195 INT226594 Positive_regulation of Phosphorylation of Ins1 6 0.22 6.42 0.48 53.40
196 INT210539 Binding of Ide 11 0.29 6.09 0.52 53.28
197 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 53.12
198 INT326524 Negative_regulation of Transcription of APOE 1 0.30 1.71 0 52.96
199 INT326073 Transcription of APOE 2 0.51 1.94 0 52.96
200 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14 52.08
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