D:Vascular Neoplasms

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Disease Term
Synonyms NEOPLASM VASCULAR, Neoplasms Vascular, VASCULAR NEOPLASM
Documents 44
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Vascular Neoplasms. They are ordered first by their relevance to Vascular Neoplasms and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32 44.48
2 INT295725 PTGER2 Positive_regulation of RAC2 1 0.05 1.92 0.32 44.48
3 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74 5.00
4 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7 5.00
5 INT295705 Binding of IK and TNF 1 0.00 0.27 0.64 5.00
6 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6 5.00
7 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6 5.00
8 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49 5.00
9 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 5.00
10 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41 5.00
11 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33 5.00
12 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33 5.00
13 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21 5.00
14 INT295715 PTGER2 Regulation of Localization of FGF2 1 0.02 0.6 0.05 5.00
15 INT295719 VEGFA Regulation of Localization of PTGER2 1 0.02 0.6 0.05 5.00
16 INT295723 VEGFA Regulation of Localization of FGF2 1 0.07 0.6 0.05 5.00
17 INT295718 Binding of PTGER2 and Positive_regulation of Positive_regulation of SP1 1 0.02 0.58 0.04 5.00
18 INT295702 PTGER2 Positive_regulation of Racgap1 1 0.05 0.22 0 5.00
19 INT295710 PTGER2 Regulation of Positive_regulation of RAC1 1 0.01 1.62 0 5.00
20 INT295701 Positive_regulation of Binding of RAC1 and Racgap1 1 0.28 0.16 0 5.00
21 INT295704 Positive_regulation of Binding of RHOA and Racgap1 1 0.15 0.16 0 5.00
22 INT295706 PTGER2 Regulation of Regulation of RHOA 1 0.01 0.61 0 5.00
23 INT295714 PTGER2 Positive_regulation of RHOA 1 0.01 0.34 0 5.00
24 INT295700 Binding of RAC1 and Racgap1 1 0.21 0.16 0 5.00
25 INT295703 Binding of RHOA and Racgap1 1 0.11 0.16 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Vascular Neoplasms. They are ordered first by their pain relevance and then by number of times they were reported in Vascular Neoplasms. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT23598 Binding of SCN5A 32 0.40 16 5.35 98.52
2 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 93.32
3 INT166312 Negative_regulation of Vim 7 0.22 5.9 0.46 90.08
4 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 80.52
5 INT147464 Binding of Ptprc 13 0.36 15.18 0.98 80.40
6 INT167735 Positive_regulation of DNAI1 2 0.49 2.88 0.52 75.40
7 INT51445 Binding of B3GAT1 9 0.47 4.64 3.95 75.00
8 INT82374 Binding of SYP 13 0.36 13.69 0.85 75.00
9 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67 63.84
10 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 63.84
11 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 63.84
12 INT21502 Gene_expression of Scn4a 22 0.78 4.47 7.97 63.84
13 INT20705 Positive_regulation of Scn4a 18 0.68 4.34 7.85 63.44
14 INT91417 Positive_regulation of PTGES 36 0.68 18.45 7.64 63.44
15 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59 62.24
16 INT35487 Localization of PTGER2 103 0.46 51.24 17.45 61.40
17 INT103238 Localization of PTGES 7 0.68 4.16 2.59 60.80
18 INT58283 Localization of ABCC1 8 0.23 6.07 2.08 56.60
19 INT55687 Localization of TIMP1 47 0.74 30.24 12.31 56.20
20 INT295694 Localization of DNAI1 4 0.15 3.28 1.09 56.20
21 INT295682 Regulation of Localization of DNAI1 1 0.08 1.87 0.37 56.20
22 INT295679 Regulation of Localization of TIMP1 1 0.17 2.7 0.93 55.76
23 INT189852 Localization of H2-Q13 4 0.06 4.1 0.47 54.96
24 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75 39.36
25 INT295683 Positive_regulation of RAC2 1 0.49 1.72 0.3 39.36
26 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 31.16
27 INT69952 Positive_regulation of IK 45 0.32 16.08 14.59 25.00
28 INT1762 Negative_regulation of PTGER2 64 0.43 28.21 11.27 25.00
29 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 25.00
30 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
31 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
32 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
33 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
34 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
35 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 5.00
36 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
37 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
38 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
39 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
40 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
41 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
42 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06 5.00
43 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
44 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
45 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 5.00
46 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 5.00
47 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
48 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 5.00
49 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
50 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
51 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
52 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23 5.00
53 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 5.00
54 INT65698 Localization of CCL2 118 0.81 77.54 32.69 5.00
55 INT99610 Localization of MMP9 126 0.79 48.46 32.67 5.00
56 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 5.00
57 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
58 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
59 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 5.00
60 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
61 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 5.00
62 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
63 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 5.00
64 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 5.00
65 INT34487 Localization of MMP2 56 0.81 31.41 23.61 5.00
66 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 5.00
67 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 5.00
68 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
69 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
70 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
71 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 5.00
72 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
73 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 5.00
74 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 5.00
75 INT66857 Regulation of CCL2 39 0.53 28.55 18.35 5.00
76 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 5.00
77 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 5.00
78 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16 5.00
79 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 5.00
80 INT50671 Regulation of Gene_expression of CPOX 45 0.54 30.99 13.83 5.00
81 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 5.00
82 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 5.00
83 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
84 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 5.00
85 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95 5.00
86 INT34485 Negative_regulation of Localization of MMP2 17 0.50 9.96 10.49 5.00
87 INT89282 Regulation of MMP9 39 0.60 25.45 10.34 5.00
88 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 5.00
89 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 5.00
90 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
91 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 5.00
92 INT68133 Localization of Fgf2 36 0.81 15.37 9.14 5.00
93 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
94 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93 5.00
95 INT66213 Localization of RELA 63 0.78 14.71 8.77 5.00
96 INT73558 Regulation of IK 23 0.23 12.02 8.73 5.00
97 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 5.00
98 INT113987 Localization of IK 29 0.23 16.73 8.25 5.00
99 INT81777 Negative_regulation of Gene_expression of IK 22 0.08 11.55 8.09 5.00
100 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79 5.00
101 INT108628 Regulation of MMP2 27 0.60 14.85 6.06 5.00
102 INT58393 Positive_regulation of Localization of PTGER2 37 0.25 16.8 6 5.00
103 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86 5.00
104 INT32155 Gene_expression of TNFRSF10B 36 0.67 30.32 5.74 5.00
105 INT150853 Negative_regulation of Cxcl1 22 0.49 12.61 5.72 5.00
106 INT98685 Positive_regulation of Gene_expression of PTGES 28 0.68 9.46 5.55 5.00
107 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47 5.00
108 INT150856 Localization of Cxcl1 14 0.78 6.97 4.91 5.00
109 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
110 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7 5.00
111 INT107605 Gene_expression of MMP14 26 0.64 25.88 4.49 5.00
112 INT1209 Binding of Kitl 14 0.37 6.72 4.3 5.00
113 INT58390 Negative_regulation of Localization of PTGER2 25 0.21 14.4 4.25 5.00
114 INT113282 Negative_regulation of TNFRSF11B 17 0.57 13.71 4.17 5.00
115 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17 5.00
116 INT174195 Negative_regulation of HLA-E 31 0.42 11.98 3.88 5.00
117 INT121661 Binding of CXCL12 25 0.37 11.27 3.82 5.00
118 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48 5.00
119 INT100400 Localization of CCL17 3 0.61 3.42 3.46 5.00
120 INT121967 Regulation of RAC1 9 0.45 6.14 3.41 5.00
121 INT55690 Positive_regulation of Localization of TIMP1 8 0.50 4.77 3.28 5.00
122 INT61500 Binding of FN1 39 0.48 27.33 3.13 5.00
123 INT25122 Binding of PTGER2 31 0.31 13.83 3.12 5.00
124 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09 5.00
125 INT234717 Regulation of Cxcl1 10 0.41 6.14 2.9 5.00
126 INT234716 Negative_regulation of Gene_expression of Cxcl1 10 0.48 9.31 2.86 5.00
127 INT194661 Binding of CCL5 9 0.46 6.07 2.73 5.00
128 INT32153 Positive_regulation of Gene_expression of TNFRSF10B 14 0.49 10.81 2.61 5.00
129 INT232510 Negative_regulation of Gene_expression of CXCR4 18 0.58 20.27 2.54 5.00
130 INT97902 Gene_expression of AGGF1 17 0.11 13.45 2.51 5.00
131 INT24672 Localization of FGF2 27 0.71 14.59 2.48 5.00
132 INT59784 Binding of DES 22 0.47 19.48 2.27 5.00
133 INT118791 Binding of AKT1 32 0.48 15.51 2.25 5.00
134 INT58392 Regulation of Localization of PTGER2 10 0.25 5.18 2.19 5.00
135 INT70987 Binding of RAC1 14 0.37 12.14 2.13 5.00
136 INT295676 Localization of CCL8 3 0.49 6.05 2.11 5.00
137 INT99636 Negative_regulation of Localization of Fgf2 4 0.41 1.32 1.97 5.00
138 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92 5.00
139 INT284521 Negative_regulation of CX3CL1 11 0.27 13.86 1.87 5.00
140 INT85348 Localization of RHOA 12 0.59 4.81 1.83 5.00
141 INT150852 Positive_regulation of Localization of Cxcl1 5 0.51 2.82 1.72 5.00
142 INT113110 Negative_regulation of CXCL12 8 0.43 6.01 1.63 5.00
143 INT181422 Localization of CCL15 2 0.22 1.76 1.62 5.00
144 INT88726 Gene_expression of HPRT1 36 0.78 10.12 1.58 5.00
145 INT34486 Regulation of Localization of MMP2 4 0.35 2.19 1.54 5.00
146 INT295688 Positive_regulation of Regulation of MMP9 1 0.14 0.67 1.51 5.00
147 INT82292 Negative_regulation of ABCC1 8 0.59 1.55 1.39 5.00
148 INT130647 Regulation of Gene_expression of CXCL12 6 0.39 5.01 1.38 5.00
149 INT245089 Localization of CXCL12 8 0.65 10.17 1.28 5.00
150 INT66852 Gene_expression of Fcer2 15 0.14 9.74 1.27 5.00
151 INT74254 Binding of PTPRC 16 0.36 8.37 1.27 5.00
152 INT128176 Regulation of RHOA 13 0.44 4.35 1.26 5.00
153 INT48554 Positive_regulation of SP1 12 0.49 3.64 1.2 5.00
154 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12 5.00
155 INT173589 Localization of OSM 4 0.58 1.65 1.07 5.00
156 INT78354 Positive_regulation of Positive_regulation of CPOX 8 0.19 2.82 1.06 5.00
157 INT13817 Protein_catabolism of EGF 3 1.00 1.44 1.06 5.00
158 INT34234 Positive_regulation of Positive_regulation of PTGER2 8 0.28 3.69 1.04 5.00
159 INT96581 Negative_regulation of Negative_regulation of MMP2 4 0.57 3.1 1.04 5.00
160 INT279394 Positive_regulation of Localization of IK 5 0.09 2.67 1.03 5.00
161 INT86559 Negative_regulation of KITLG 8 0.41 3.54 0.99 5.00
162 INT295685 Positive_regulation of Localization of CCL15 1 0.05 1.31 0.91 5.00
163 INT153327 Gene_expression of Aspscr1 5 0.57 3.28 0.91 5.00
164 INT295692 Localization of CCL7 1 0.06 1.22 0.89 5.00
165 INT295611 Regulation of DNAI1 5 0.23 2.41 0.87 5.00
166 INT273180 Negative_regulation of Localization of IK 3 0.03 1.51 0.85 5.00
167 INT237971 Regulation of Gene_expression of TNFRSF10B 3 0.23 3.52 0.76 5.00
168 INT193261 Positive_regulation of Regulation of PTGER2 3 0.28 2.14 0.76 5.00
169 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72 5.00
170 INT245941 Regulation of ABCC1 3 0.26 1.61 0.69 5.00
171 INT291371 Positive_regulation of Localization of CXCL12 2 0.35 2.8 0.65 5.00
172 INT166024 Protein_catabolism of AKT1 5 0.46 2.6 0.64 5.00
173 INT260422 Positive_regulation of Localization of EGF 3 0.10 1.58 0.56 5.00
174 INT142907 Regulation of Localization of Fgf2 1 0.44 1.16 0.53 5.00
175 INT198048 Protein_catabolism of PDGFA 2 0.28 2.05 0.5 5.00
176 INT291367 Negative_regulation of Gene_expression of CXCL12 3 0.32 4.15 0.47 5.00
177 INT92592 Transcription of PTGER2 6 0.32 4.52 0.47 5.00
178 INT199077 Localization of Racgap1 7 0.73 2.43 0.42 5.00
179 INT47651 Gene_expression of DERL2 7 0.68 7.85 0.38 5.00
180 INT82817 Localization of FGF1 2 0.60 2.12 0.36 5.00
181 INT295671 Protein_catabolism of AGGF1 1 0.01 0.59 0.35 5.00
182 INT295690 Negative_regulation of Regulation of MMP9 1 0.11 0.99 0.33 5.00
183 INT183879 Binding of RHOA 6 0.34 2.1 0.31 5.00
184 INT295677 Negative_regulation of FSD1 1 0.09 1.19 0.27 5.00
185 INT159362 Binding of Pecam1 2 0.23 0.89 0.27 5.00
186 INT152681 Gene_expression of PDPN 29 0.65 23.06 0.18 5.00
187 INT295673 Regulation of FGF4 1 0.05 0.83 0.17 5.00
188 INT295674 Regulation of Regulation of ABCC1 1 0.00 1.03 0.14 5.00
189 INT206158 Regulation of CDC42EP1 3 0.01 1.44 0.14 5.00
190 INT80643 Regulation of Binding of FN1 2 0.09 1.27 0.11 5.00
191 INT347444 Gene_expression of KRTAP5-2 1 0.16 1.4 0.09 5.00
192 INT162478 Gene_expression of KRT6B 2 0.75 1.39 0.08 5.00
193 INT295681 Positive_regulation of CDC42EP1 1 0.01 2.63 0 5.00
194 INT295672 Regulation of Positive_regulation of CDC42EP1 1 0.00 1.07 0 5.00
195 INT295675 Protein_catabolism of RHOA 2 0.24 0.21 0 5.00
196 INT295687 Positive_regulation of Binding of RAC1 1 0.25 0 0 5.00
197 INT295678 Regulation of Positive_regulation of RAC1 1 0.23 1.55 0 5.00
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