D:Vasoplegia

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pChart

Disease Term
Synonyms Post Operative Vasoplegic Syndrome, Post Operative Vasoplegic Syndromes, Postoperative Vasoplegic Syndrome, Syndrome Post Operative Vasoplegic, SYNDROMES POST OPERATIVE VASOPLEGIC, Vasoplegias, VASOPLEGIC SYNDROME, VASOPLEGIC SYNDROME POST OPERATIVE, Vasoplegic Syndromes Post Operative
Documents 20
Hot Single Events 25
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Vasoplegia. They are ordered first by their relevance to Vasoplegia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT330598 Binding of Il6 and Fig4 1 0.11 1.78 0.4 86.08
2 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26 84.72
3 INT353041 IL4 Positive_regulation of Localization of IL1B 1 0.02 0.99 0.16 84.72
4 INT353036 IL4 Positive_regulation of Localization of IL10 1 0.03 0.99 0.16 84.72
5 INT353038 IL4 Positive_regulation of Localization of IL2 1 0.02 0.99 0.16 84.72
6 INT353039 IL4 Positive_regulation of Localization of IL8 1 0.02 0.99 0.16 84.72
7 INT353037 IL4 Positive_regulation of IL2 1 0.02 0.99 0.16 84.04
8 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 83.80
9 INT353040 IL4 Positive_regulation of IL8 1 0.02 0.99 0.16 83.80
10 INT177661 Binding of Trib3 and Myo1f 1 0.00 0.54 0.24 5.00
11 INT177675 Binding of CALM1 and Positive_regulation of Trib3 1 0.00 0.27 0.12 5.00
12 INT177674 CALM1 Positive_regulation of Trib3 1 0.00 0.27 0.12 5.00
13 INT177676 Binding of Trib3 and Myo1f Positive_regulation of Trib3 1 0.00 0.3 0.1 5.00
14 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07 5.00
15 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05 5.00
16 INT254161 Epo Positive_regulation of Nos2 1 0.37 0.54 0.05 5.00
17 INT254162 Epo Positive_regulation of NOS1 1 0.01 0.53 0.05 5.00
18 INT191214 Cotl1 Positive_regulation of Prkcg 1 0.10 1.35 0.04 5.00
19 INT191217 Cotl1 Positive_regulation of Amigo2 1 0.02 0.61 0.03 5.00
20 INT177672 Vmn1r51 Positive_regulation of Localization of Ptgis 1 0.00 0.24 0.03 5.00
21 INT158391 Oxt Positive_regulation of Localization of Nppa 2 0.27 0.64 0.03 5.00
22 INT177671 Vmn1r51 Positive_regulation of Localization of Nppa 1 0.01 0.24 0.03 5.00
23 INT191220 Cotl1 Positive_regulation of Edn1 1 0.19 0.69 0 5.00
24 INT191218 Edn1 Regulation of Positive_regulation of Prkcg 1 0.14 0.32 0 5.00
25 INT177673 Avp Positive_regulation of Vmn1r51 1 0.04 0.53 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Vasoplegia. They are ordered first by their pain relevance and then by number of times they were reported in Vasoplegia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.50
2 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 99.50
3 INT49768 Positive_regulation of Kcnj5 58 0.41 11.89 16.02 97.52
4 INT6852 Localization of TNF 883 0.81 705.95 270.84 84.72
5 INT6849 Localization of IL1B 229 0.81 112.56 69.63 84.72
6 INT12339 Localization of IL8 437 0.81 251.87 117.39 84.72
7 INT12082 Localization of IL6 365 0.81 241.78 105.78 84.72
8 INT10763 Localization of IL2 157 0.80 81.11 33.21 84.72
9 INT74423 Localization of IL10 91 0.80 61.6 22.95 84.72
10 INT69158 Localization of IL4 48 0.71 31.3 11.98 84.72
11 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 84.28
12 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 84.04
13 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 84.04
14 INT22383 Binding of IL2 59 0.48 39.06 8.56 84.04
15 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 83.80
16 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 83.80
17 INT77146 Binding of IL4 23 0.36 13.69 5.39 83.80
18 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 83.56
19 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 83.56
20 INT86437 Binding of IL6 154 0.48 121.22 29.3 83.56
21 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 83.32
22 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 83.32
23 INT10834 Binding of IL8 65 0.48 41.66 16.53 83.32
24 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 83.08
25 INT142162 Binding of IL10 30 0.37 21.9 4.84 83.08
26 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06 76.24
27 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 75.68
28 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49 70.28
29 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 68.72
30 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 65.76
31 INT35501 Positive_regulation of Myo1f 5 0.69 1.73 0.39 64.68
32 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69 64.24
33 INT95338 Positive_regulation of Positive_regulation of CASP1 9 0.49 4.61 1.43 64.24
34 INT26172 Gene_expression of C10orf10 6 0.65 1.11 2.75 50.00
35 INT306224 Positive_regulation of C10orf10 1 0.67 0.96 0.07 50.00
36 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 46.64
37 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 46.04
38 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 45.52
39 INT119195 Binding of Cotl1 11 0.14 6.77 2.21 33.76
40 INT68529 Negative_regulation of ADRA2B 3 0.14 0.79 0.47 28.20
41 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 20.32
42 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 16.88
43 INT78032 Regulation of Oxtr 12 0.62 0.72 1.09 7.08
44 INT177651 Regulation of Vmn1r51 1 0.04 0.43 0.03 7.08
45 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
46 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
47 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
48 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 5.00
49 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 5.00
50 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
51 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 5.00
52 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
53 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
54 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 5.00
55 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
56 INT4207 Regulation of Avp 267 0.62 63.72 115.33 5.00
57 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
58 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44 5.00
59 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 5.00
60 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
61 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
62 INT5617 Localization of Nppa 266 0.81 83.51 83.89 5.00
63 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 5.00
64 INT12536 Localization of Prkcg 101 0.80 36.37 73.81 5.00
65 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
66 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17 5.00
67 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
68 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
69 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
70 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 5.00
71 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 5.00
72 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 5.00
73 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
74 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 5.00
75 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
76 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
77 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45 5.00
78 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21 5.00
79 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81 5.00
80 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67 5.00
81 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 5.00
82 INT894 Binding of Avp 84 0.48 29.16 29.63 5.00
83 INT32165 Binding of CALM1 92 0.48 24.19 29.57 5.00
84 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 5.00
85 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 5.00
86 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 5.00
87 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 5.00
88 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 5.00
89 INT7827 Binding of Cck 32 0.48 4.66 23.73 5.00
90 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 5.00
91 INT171820 Localization of Fig4 144 0.65 27.38 20.88 5.00
92 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96 5.00
93 INT5048 Binding of Edn1 55 0.47 18.86 19.16 5.00
94 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78 5.00
95 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 5.00
96 INT170033 Positive_regulation of Gene_expression of Fig4 59 0.43 20.99 16.69 5.00
97 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18 5.00
98 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15 5.00
99 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 5.00
100 INT6365 Localization of Edn1 56 0.81 18.84 13.83 5.00
101 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 5.00
102 INT22213 Localization of Gpt 52 0.78 34.05 12.94 5.00
103 INT55343 Localization of Ros1 39 0.60 34.51 12.5 5.00
104 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36 5.00
105 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
106 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 5.00
107 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 5.00
108 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2 5.00
109 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13 5.00
110 INT5249 Gene_expression of Hrasls 8 0.58 10.39 6.27 5.00
111 INT69974 Positive_regulation of Oxtr 30 0.70 2.44 5.73 5.00
112 INT31762 Gene_expression of Itpr3 22 0.74 1.6 4.15 5.00
113 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36 5.00
114 INT130616 Positive_regulation of Negative_regulation of Prkcg 5 0.48 1.6 3.08 5.00
115 INT50272 Positive_regulation of Cotl1 24 0.40 6.57 2.77 5.00
116 INT79609 Positive_regulation of Negative_regulation of Nos2 5 0.49 3.6 2.43 5.00
117 INT191221 Positive_regulation of Amigo2 20 0.12 24.24 2.31 5.00
118 INT63081 Localization of Itpr3 13 0.67 1.08 2.12 5.00
119 INT66240 Localization of Ptgis 9 0.58 1.36 1.95 5.00
120 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79 5.00
121 INT42065 Phosphorylation of Myo1f 13 0.38 2.05 1.71 5.00
122 INT178023 Regulation of Epo 11 0.45 3.87 1.22 5.00
123 INT119196 Gene_expression of Cotl1 13 0.24 12.2 1.15 5.00
124 INT185929 Regulation of Gene_expression of IRF6 9 0.20 1.66 0.99 5.00
125 INT191222 Binding of Amigo2 4 0.05 5.42 0.87 5.00
126 INT187508 Positive_regulation of Localization of Ros1 7 0.15 3.85 0.71 5.00
127 INT191225 Regulation of Hspg2 3 0.06 1.04 0.68 5.00
128 INT330597 Positive_regulation of Hcuc4 1 0.02 1.43 0.6 5.00
129 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35 5.00
130 INT330595 Regulation of Localization of Gpt 1 0.02 1.05 0.25 5.00
131 INT152680 Negative_regulation of THBD 3 0.29 1.87 0.21 5.00
132 INT224349 Gene_expression of RELT 2 0.07 1.48 0.21 5.00
133 INT177664 Gene_expression of Avpr2 3 0.35 0.49 0.2 5.00
134 INT177652 Positive_regulation of Vmn1r51 1 0.07 0.92 0.09 5.00
135 INT191224 Positive_regulation of Positive_regulation of Amigo2 2 0.06 1.62 0.07 5.00
136 INT330596 Protein_catabolism of Gpt 1 0.05 0.13 0.07 5.00
137 INT220284 Phosphorylation of Epo 2 0.63 1.2 0.03 5.00
138 INT177667 Positive_regulation of Gene_expression of Avpr2 1 0.31 0.27 0 5.00
139 INT191223 Phosphorylation of Cotl1 1 0.29 0.58 0 5.00
140 INT177668 Regulation of Gene_expression of Avpr2 1 0.20 0.39 0 5.00
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