D:Ventricular Tachycardia

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pChart

Disease Term
Synonyms Tachycardia Ventricular, TACHYCARDIAS VENTRICULAR, Ventricular Tachyarrhythmia, VENTRICULAR TACHYCARDIA DISORDER, VENTRICULAR TACHYCARDIAS, Vt Ventricular Tachycardia
Documents 135
Hot Single Events 30
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Ventricular Tachycardia. They are ordered first by their relevance to Ventricular Tachycardia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT138469 Cpb2 Negative_regulation of Gene_expression of Ryr2 1 0.04 0.25 0.32 99.52
2 INT194101 MKLN1 Positive_regulation of Binding of SCD 1 0.08 1.16 0 75.00
3 INT194102 MKLN1 Regulation of Positive_regulation of SCD 1 0.07 1.13 0 75.00
4 INT194100 Binding of MKLN1 and HELT 1 0.01 1.23 0.21 50.00
5 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
6 INT213144 TIMP1 Negative_regulation of THBD 1 0.04 1.16 0.12 5.00
7 INT213147 DAK Negative_regulation of THBD 1 0.00 1.16 0.12 5.00
8 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11 5.00
9 INT213145 DAK Positive_regulation of TIMP1 1 0.02 0.36 0.09 5.00
10 INT213149 DAK Regulation of HSD11B1 1 0.00 1.42 0 5.00
11 INT213148 TIMP1 Regulation of DAK 1 0.01 0.73 0 5.00
12 INT213146 TIMP1 Regulation of HSD11B1 1 0.02 0.7 0 5.00
13 INT213143 DAK Regulation of TIMP1 1 0.01 0.73 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Ventricular Tachycardia. They are ordered first by their pain relevance and then by number of times they were reported in Ventricular Tachycardia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT40476 Negative_regulation of RFC1 5 0.18 2.85 0.72 99.82
2 INT182074 Negative_regulation of Gene_expression of RFC1 1 0.03 0.76 0.08 99.82
3 INT163359 Gene_expression of RFC1 9 0.65 3.34 2.64 99.34
4 INT14954 Gene_expression of COLQ 7 0.52 2.59 1.39 99.12
5 INT138468 Negative_regulation of Gene_expression of Ryr2 1 0.17 0.25 0.32 99.04
6 INT221865 Positive_regulation of Localization of RYR2 2 0.15 4.56 0.05 98.92
7 INT192016 Localization of RYR2 5 0.25 4.18 0.05 98.92
8 INT101687 Positive_regulation of AVPR1B 6 0.40 2.95 0.95 98.48
9 INT138467 Gene_expression of Ryr2 5 0.55 2.36 0.98 97.68
10 INT138466 Regulation of Gene_expression of Ryr2 3 0.28 1.62 0.39 97.68
11 INT327421 Localization of UBN1 1 0.02 0.72 0.27 97.60
12 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 97.12
13 INT284872 Localization of Scn3b 1 0.65 1.28 0.08 97.04
14 INT214 Localization of AVP 370 0.81 208.51 91.09 96.92
15 INT193624 Binding of ARVD4 1 0.31 1.14 0.08 96.00
16 INT8799 Negative_regulation of Csrp1 24 0.58 11.01 6.86 93.88
17 INT194104 Regulation of MKLN1 1 0.22 1.81 0 91.76
18 INT192006 Gene_expression of RYR2 5 0.23 7.69 0.44 91.12
19 INT193632 Positive_regulation of ARVD4 2 0.01 2.73 0.11 90.96
20 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96 89.92
21 INT207165 Gene_expression of DAK 18 0.08 9.41 2.69 87.12
22 INT179693 Positive_regulation of DAK 14 0.04 6.02 1.4 87.12
23 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 86.48
24 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 86.48
25 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 86.48
26 INT16923 Positive_regulation of Tnni3 32 0.50 25.01 5.44 86.24
27 INT193271 Gene_expression of Brs3 8 0.05 1.25 5.87 83.96
28 INT8475 Positive_regulation of COLQ 14 0.45 1.36 3.37 82.40
29 INT300722 Positive_regulation of Ptrf 1 0.40 2.58 0 80.64
30 INT4711 Regulation of ELK3 17 0.62 2.36 4.26 80.64
31 INT193623 Transcription of ARVD4 1 0.58 1.63 0 77.08
32 INT188993 Gene_expression of MKLN1 2 0.38 9.71 1.43 75.00
33 INT3915 Gene_expression of SCD 25 0.57 13.94 6 75.00
34 INT73611 Negative_regulation of SCD 15 0.37 26.67 3.71 75.00
35 INT3854 Binding of SCD 16 0.41 11.14 3.7 75.00
36 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 75.00
37 INT24472 Positive_regulation of Brs3 5 0.28 1 1.73 71.08
38 INT8541 Gene_expression of Csrp1 42 0.76 23.72 6.9 68.96
39 INT284877 Transcription of Scn5a 3 0.72 1.41 0.3 68.40
40 INT226836 Transcription of Scn1b 2 0.50 0.91 0.07 68.40
41 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 66.36
42 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 66.16
43 INT300718 Negative_regulation of Ptrf 1 0.34 4.1 0.18 64.84
44 INT300715 Regulation of Localization of Ptrf 1 0.36 1.18 0.03 64.84
45 INT300720 Localization of Ptrf 1 0.59 1.57 0.03 64.84
46 INT300719 Regulation of Binding of Cav3 1 0.25 1.17 0.04 63.64
47 INT300713 Regulation of Localization of Cav1 2 0.42 1.37 0.04 63.64
48 INT300721 Regulation of Localization of Cav3 1 0.41 1.17 0.04 63.64
49 INT214975 Localization of Cav1 7 0.75 2.7 0.13 63.24
50 INT300711 Localization of Cav3 1 0.69 1.17 0.04 63.24
51 INT220506 Binding of Cav1 13 0.45 5.46 0.38 62.56
52 INT237337 Binding of Cav3 3 0.44 2.63 0.11 62.56
53 INT284882 Positive_regulation of Scn5a 3 0.50 1.73 0.44 60.48
54 INT284871 Positive_regulation of Scn1b 1 0.44 0.27 0.04 57.76
55 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 57.08
56 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95 56.24
57 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11 56.08
58 INT300717 Gene_expression of Ptrf 1 0.61 3.64 0.18 54.48
59 INT300714 Positive_regulation of Gene_expression of Ptrf 1 0.55 1.16 0.04 54.48
60 INT9764 Gene_expression of Adrb3 10 0.62 4.14 2.33 51.92
61 INT284870 Regulation of Scn3b 1 0.45 0.45 0.34 50.68
62 INT107135 Positive_regulation of KCNJ5 4 0.09 2.78 1.3 50.00
63 INT194106 Positive_regulation of MKLN1 1 0.25 4.34 0.64 50.00
64 INT189002 Binding of MKLN1 2 0.24 0.97 0.38 50.00
65 INT194105 Localization of MKLN1 1 0.37 0.37 0.18 50.00
66 INT194103 Negative_regulation of MKLN1 1 0.21 1.57 0.08 50.00
67 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11 48.04
68 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 47.00
69 INT193268 Binding of Brs3 3 0.03 1.56 2.67 45.60
70 INT217952 Negative_regulation of MYH7 2 0.01 1.85 0.09 41.36
71 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85 40.24
72 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 40.16
73 INT213155 Positive_regulation of Regulation of HSD11B1 1 0.04 0.41 0 40.16
74 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 39.36
75 INT284873 Negative_regulation of Scn3b 1 0.43 0.35 0.06 34.56
76 INT62992 Regulation of COLQ 1 0.26 0.6 0.3 34.32
77 INT284875 Transcription of Scn3b 1 0.53 0.4 0 24.88
78 INT148384 Positive_regulation of HEY1 19 0.43 29.76 5.89 10.80
79 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 5.00
80 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
81 INT162 Regulation of Prl 794 0.62 165.01 322.24 5.00
82 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 5.00
83 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
84 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
85 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 5.00
86 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
87 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
88 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
89 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
90 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
91 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
92 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 5.00
93 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
94 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 5.00
95 INT921 Regulation of GH1 172 0.60 52.88 51.04 5.00
96 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 5.00
97 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 5.00
98 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 5.00
99 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 5.00
100 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
101 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 5.00
102 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
103 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 5.00
104 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
105 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 5.00
106 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
107 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31 5.00
108 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52 5.00
109 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 5.00
110 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 5.00
111 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46 5.00
112 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 5.00
113 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
114 INT106745 Localization of CRP 65 0.81 66.44 15.21 5.00
115 INT75908 Regulation of LEP 77 0.60 60.16 15.19 5.00
116 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 5.00
117 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
118 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55 5.00
119 INT55687 Localization of TIMP1 47 0.74 30.24 12.31 5.00
120 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65 5.00
121 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
122 INT43009 Gene_expression of Scn7a 45 0.68 7.85 10.29 5.00
123 INT110110 Gene_expression of ACCS 85 0.58 75.88 10.2 5.00
124 INT57424 Positive_regulation of TNNT1 42 0.67 31.84 9.7 5.00
125 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 5.00
126 INT36678 Binding of TIMP1 33 0.36 14.99 7.87 5.00
127 INT17028 Positive_regulation of Scn7a 35 0.41 9.83 7.44 5.00
128 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 5.00
129 INT17029 Regulation of Scn7a 23 0.45 3.89 7.02 5.00
130 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14 5.00
131 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14 5.00
132 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06 5.00
133 INT34232 Regulation of TIMP1 37 0.61 18.76 6.05 5.00
134 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71 5.00
135 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
136 INT23598 Binding of SCN5A 32 0.40 16 5.35 5.00
137 INT151387 Gene_expression of Cav3 14 0.78 4 5.31 5.00
138 INT58060 Negative_regulation of HMI 30 0.44 11.9 5.06 5.00
139 INT14502 Gene_expression of BCHE 40 0.67 18.52 4.6 5.00
140 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
141 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75 5.00
142 INT185246 Gene_expression of Psmd1 26 0.50 8.89 3.73 5.00
143 INT84925 Transcription of NGF 11 0.65 4.13 3.65 5.00
144 INT29832 Negative_regulation of Scn7a 20 0.37 5.91 3.63 5.00
145 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49 5.00
146 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47 5.00
147 INT136266 Gene_expression of KCNQ1 23 0.64 8.34 3.11 5.00
148 INT115250 Positive_regulation of Slc2a4 16 0.67 8.13 2.64 5.00
149 INT86602 Binding of KCNH2 14 0.36 4.65 2.58 5.00
150 INT12485 Binding of DNAH8 17 0.48 4.24 2.54 5.00
151 INT24471 Regulation of Brs3 3 0.17 1.56 2.19 5.00
152 INT17688 Positive_regulation of IKZF1 5 0.50 0.48 2.11 5.00
153 INT68865 Gene_expression of ACOX1 13 0.52 5.49 2.09 5.00
154 INT83744 Gene_expression of SULT1E1 9 0.75 3.12 2.07 5.00
155 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97 5.00
156 INT17890 Negative_regulation of HMGCR 26 0.42 12.05 1.94 5.00
157 INT59194 Gene_expression of STS 18 0.59 6.74 1.89 5.00
158 INT91550 Gene_expression of PPM1D 7 0.10 0.68 1.81 5.00
159 INT151743 Binding of Gusb 11 0.24 8.73 1.63 5.00
160 INT139254 Negative_regulation of Per1 12 0.56 3.17 1.62 5.00
161 INT42250 Binding of Scn7a 7 0.33 0.51 1.48 5.00
162 INT67133 Gene_expression of Gusb 14 0.75 18.57 1.37 5.00
163 INT163747 Negative_regulation of Cav3 3 0.54 0.56 1.16 5.00
164 INT210571 Gene_expression of KCNE2 7 0.61 2.7 0.97 5.00
165 INT207496 Regulation of Gene_expression of Scn7a 8 0.04 1.1 0.89 5.00
166 INT143450 Negative_regulation of Scn5a 3 0.43 2.71 0.88 5.00
167 INT182077 Positive_regulation of RFC1 3 0.07 1.65 0.81 5.00
168 INT193269 Negative_regulation of Brs3 1 0.03 0.26 0.79 5.00
169 INT117570 Positive_regulation of Gene_expression of Scn7a 7 0.43 1.4 0.77 5.00
170 INT132662 Binding of Hcm 11 0.31 14.41 0.73 5.00
171 INT74484 Negative_regulation of WASF1 5 0.57 2.01 0.71 5.00
172 INT185647 Binding of WASF1 5 0.05 2.46 0.67 5.00
173 INT52590 Transcription of SCN5A 4 0.55 0.91 0.65 5.00
174 INT161807 Phosphorylation of ROS1 10 0.43 4.86 0.62 5.00
175 INT86246 Binding of Bcl2l1 8 0.37 6.67 0.57 5.00
176 INT213154 Positive_regulation of Binding of TIMP1 2 0.41 1.33 0.55 5.00
177 INT86601 Positive_regulation of KCNH2 7 0.49 1.56 0.52 5.00
178 INT172066 Binding of Mtpn 3 0.02 1.51 0.52 5.00
179 INT200401 Gene_expression of KCNE1 14 0.57 6.42 0.45 5.00
180 INT299511 Negative_regulation of Elpt 2 0.07 1.79 0.4 5.00
181 INT21631 Positive_regulation of Gene_expression of Adh1 4 0.70 12.56 0.39 5.00
182 INT182073 Binding of APEX1 4 0.12 1.72 0.32 5.00
183 INT290576 Positive_regulation of NPTX2 1 0.06 3.32 0.31 5.00
184 INT38330 Binding of Adh1 4 0.41 3.98 0.3 5.00
185 INT136267 Binding of KCNQ1 3 0.36 3.28 0.28 5.00
186 INT226826 Gene_expression of Scn1b 5 0.57 0.52 0.22 5.00
187 INT230722 Regulation of Hcm 4 0.37 3 0.21 5.00
188 INT193376 Gene_expression of WASF1 7 0.75 1.6 0.2 5.00
189 INT89772 Positive_regulation of APEX1 4 0.21 2.29 0.19 5.00
190 INT204348 Gene_expression of PPARGC1A 10 0.75 2.73 0.19 5.00
191 INT231220 Localization of ANK2 1 0.40 0.91 0.17 5.00
192 INT158033 Gene_expression of CEACAMP1 3 0.07 3.11 0.17 5.00
193 INT286439 Regulation of Myl3 3 0.26 1.43 0.16 5.00
194 INT193622 Positive_regulation of ICA1L 1 0.07 1.51 0.14 5.00
195 INT231217 Positive_regulation of ANK2 1 0.26 0.67 0.12 5.00
196 INT182078 Gene_expression of APEX1 3 0.59 4.77 0.12 5.00
197 INT300712 Negative_regulation of Gene_expression of Elpt 1 0.07 1.02 0.09 5.00
198 INT300716 Gene_expression of Elpt 1 0.11 1.02 0.09 5.00
199 INT212172 Binding of Adrm1 7 0.36 1.38 0.09 5.00
200 INT284878 Regulation of Scn5a 2 0.27 1.15 0.09 5.00
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