D:Vesicoureteral Reflux

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Reflux Vesico Ureteral, REFLUX VESICOURETERAL, Vesico Ureteral Reflux
Documents 156
Hot Single Events 27
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Vesicoureteral Reflux. They are ordered first by their relevance to Vesicoureteral Reflux and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT323043 Binding of CYP21A1P and HLA-DOA 1 0.04 1.48 0.06 50.08
2 INT323042 Binding of CYP21A2 and HLA-DOA 1 0.04 1.49 0.06 50.08
3 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16 5.00
4 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92 5.00
5 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64 5.00
6 INT213809 F2 Positive_regulation of F2rl3 2 0.12 0.61 0.5 5.00
7 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46 5.00
8 INT207110 Adam3 Regulation of Gene_expression of Eef1a1 1 0.01 1 0.41 5.00
9 INT207113 Nfkbia Negative_regulation of Nfkb1 1 0.11 0.96 0.4 5.00
10 INT207143 tryptase Positive_regulation of Par2 2 0.09 0.71 0.3 5.00
11 INT207114 Binding of Plau and Plaur 1 0.19 0.7 0.29 5.00
12 INT213802 Il4 Regulation of Gene_expression of Insrr 1 0.00 0.76 0.29 5.00
13 INT213808 Il12a Regulation of Gene_expression of Insrr 1 0.00 0.76 0.28 5.00
14 INT213816 Binding of Tcf12 and Tfeb 1 0.01 1.91 0.27 5.00
15 INT213798 Sh2b2 Regulation of tf 1 0.12 0.53 0.27 5.00
16 INT213799 Sh2b2 Regulation of Tfeb 1 0.26 0.54 0.27 5.00
17 INT213804 Binding of Mitf and Tfeb 1 0.24 0.81 0.24 5.00
18 INT213813 Binding of Tcf4 and Tfeb 1 0.14 0.81 0.24 5.00
19 INT213805 Binding of Tcf12 and Tcf4 1 0.00 0.79 0.23 5.00
20 INT213814 F3 Positive_regulation of Pars2 1 0.01 0.58 0.21 5.00
21 INT213812 Sh2b2 Positive_regulation of Tfeb 1 0.44 0.45 0.2 5.00
22 INT207151 PLA2G6 Positive_regulation of Localization of F2rl1 1 0.16 0.73 0.18 5.00
23 INT207147 Pla2g1b Positive_regulation of Localization of F2rl1 1 0.03 0.73 0.18 5.00
24 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17 5.00
25 INT190637 Negative_regulation of Binding of Rab7 and Rnf115 1 0.25 0.68 0.17 5.00
26 INT207142 Spg21 Positive_regulation of Par2 1 0.02 0.48 0.17 5.00
27 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17 5.00
28 INT190630 Binding of Rab7 and Rnf115 1 0.22 0.68 0.17 5.00
29 INT190635 Binding of Lmo2 and Nr1h2 1 0.09 0.59 0.16 5.00
30 INT190629 Binding of Lmo2 and Usf1 1 0.11 0.6 0.16 5.00
31 INT207144 F2r Positive_regulation of Pawr 1 0.14 0.51 0.16 5.00
32 INT190634 Binding of Lmo2 and Maz 1 0.14 0.59 0.16 5.00
33 INT190633 Binding of Lmo2 and Deaf1 1 0.18 0.59 0.16 5.00
34 INT213817 Phosphorylation of Tfe3 Positive_regulation of Mitf 1 0.22 1.22 0.15 5.00
35 INT207117 Binding of VEGFA and F2r 1 0.02 0.56 0.15 5.00
36 INT213800 Kit Positive_regulation of Mitf 1 0.30 1.24 0.15 5.00
37 INT213807 Mitf Positive_regulation of Spg21 1 0.05 1.2 0.15 5.00
38 INT213811 Tfe3 Positive_regulation of Spg21 1 0.05 1.21 0.15 5.00
39 INT213797 Kit Positive_regulation of Tfe3 1 0.28 1.24 0.14 5.00
40 INT207109 F2 Positive_regulation of Phosphorylation of Akt2 1 0.08 0.25 0.12 5.00
41 INT207112 Sh2b2 Positive_regulation of Phosphorylation of Akt2 1 0.68 0.24 0.12 5.00
42 INT207115 Sh2b2 Positive_regulation of Akt2 1 0.49 0.24 0.12 5.00
43 INT190631 Gusb Positive_regulation of Tlr4 1 0.08 0.44 0.11 5.00
44 INT190529 IFNA1 Positive_regulation of Transcription of TRIM63 1 0.00 0.39 0.08 5.00
45 INT190636 Nr1h2 Positive_regulation of Rnf115 1 0.20 0.71 0.08 5.00
46 INT213815 Binding of Tfeb and Stub1 1 0.13 0.09 0.04 5.00
47 INT213803 Binding of Foxm1 and Tfe3 1 0.00 1.09 0.03 5.00
48 INT213810 Binding of Foxm1 and Tfeb 1 0.00 1.09 0.03 5.00
49 INT213801 Binding of Tcf12 and Tfe3 1 0.01 1.11 0.03 5.00
50 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0 5.00
51 INT287088 Binding of EEC1 and Vamp3 1 0.09 1.02 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Vesicoureteral Reflux. They are ordered first by their pain relevance and then by number of times they were reported in Vesicoureteral Reflux. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT152060 Gene_expression of VUR 75 0.67 83.83 2.34 100.00
2 INT17817 Binding of VUR 41 0.48 46.85 0.95 100.00
3 INT38379 Positive_regulation of VUR 15 0.58 15 0.71 100.00
4 INT117313 Negative_regulation of VUR 11 0.42 12.14 0.39 100.00
5 INT237382 Localization of VUR 11 0.72 14.58 0.11 100.00
6 INT57070 Protein_catabolism of VUR 19 0.99 18.75 0.76 100.00
7 INT161749 Regulation of VUR 9 0.39 9.3 0.46 100.00
8 INT263006 Phosphorylation of VUR 1 0.71 6.13 0 100.00
9 INT237383 Positive_regulation of Protein_catabolism of VUR 3 0.50 4.25 0.04 100.00
10 INT237385 Negative_regulation of Binding of VUR 3 0.37 4.5 0.05 100.00
11 INT237384 Positive_regulation of Localization of VUR 2 0.43 2.85 0 100.00
12 INT240748 Positive_regulation of Gene_expression of VUR 2 0.41 6.74 0.32 100.00
13 INT263949 Negative_regulation of Protein_catabolism of VUR 1 0.37 1.73 0.07 100.00
14 INT263950 Regulation of Negative_regulation of VUR 1 0.39 1.36 0 100.00
15 INT263948 Positive_regulation of Binding of VUR 1 0.43 0.61 0.06 100.00
16 INT240747 Regulation of Localization of VUR 1 0.20 1.42 0 100.00
17 INT240746 Negative_regulation of Localization of VUR 1 0.19 1.41 0 100.00
18 INT238385 Regulation of Binding of VUR 2 0.39 0.63 0.14 100.00
19 INT263947 Positive_regulation of Negative_regulation of VUR 1 0.49 0.98 0 100.00
20 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98 99.46
21 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 90.72
22 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95 90.72
23 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59 89.52
24 INT56375 Positive_regulation of AMBP 25 0.60 21.24 2.22 86.96
25 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 85.52
26 INT312398 Positive_regulation of PCNT 3 0.40 0.75 0.53 84.24
27 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 80.88
28 INT165727 Positive_regulation of spc 3 0.21 3.24 0.25 79.40
29 INT228916 Transcription of spc 2 0.30 1.62 0.18 79.40
30 INT251 Regulation of INS 398 0.62 232.47 55.04 75.92
31 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9 75.92
32 INT190579 Negative_regulation of Localization of Ssh1 1 0.16 0.46 0 69.80
33 INT190589 Localization of Ssh1 1 0.28 0.68 0 68.84
34 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26 66.44
35 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 65.72
36 INT323052 Gene_expression of TNXB 1 0.70 1.43 0.07 64.40
37 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 61.60
38 INT323050 Positive_regulation of TNXB 1 0.45 1.43 0.07 58.16
39 INT192951 Negative_regulation of AES 15 0.38 6.38 3.5 53.92
40 INT14572 Binding of INS 205 0.48 175.43 13.38 51.12
41 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 50.00
42 INT230645 Binding of PLEC 3 0.47 0.8 0.12 41.40
43 INT70450 Binding of KRT5 6 0.47 5.72 0.08 41.40
44 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 37.16
45 INT323049 Positive_regulation of IGKV2-30 1 0.00 3.44 0.07 32.16
46 INT117496 Gene_expression of Par2 18 0.61 9.2 8.61 31.84
47 INT207108 Gene_expression of Pawr 5 0.40 1.61 0.77 31.32
48 INT180626 Gene_expression of spc 6 0.34 6.83 0.15 30.72
49 INT287082 Gene_expression of Vamp3 1 0.18 0.99 0.11 28.32
50 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
51 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
52 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
53 INT695 Binding of POMC 304 0.48 56.66 126.85 5.00
54 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
55 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 5.00
56 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 5.00
57 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 5.00
58 INT920 Localization of PLOD1 223 0.81 42.25 78.7 5.00
59 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 5.00
60 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 5.00
61 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 5.00
62 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
63 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 5.00
64 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 5.00
65 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97 5.00
66 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
67 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 5.00
68 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 5.00
69 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 5.00
70 INT917 Positive_regulation of Localization of PLOD1 51 0.69 8.53 22.87 5.00
71 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
72 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 5.00
73 INT23224 Gene_expression of tf 99 0.56 60.22 22.03 5.00
74 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 5.00
75 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89 5.00
76 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 5.00
77 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 5.00
78 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33 5.00
79 INT23226 Positive_regulation of tf 23 0.43 15.55 14.37 5.00
80 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16 5.00
81 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67 5.00
82 INT3597 Positive_regulation of Pla2g1b 37 0.63 17.94 11.41 5.00
83 INT17584 Regulation of tf 12 0.50 4.69 10.39 5.00
84 INT181488 Positive_regulation of Spg21 13 0.12 15.52 10.03 5.00
85 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32 5.00
86 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21 5.00
87 INT109005 Gene_expression of Proc 61 0.75 37.86 8.49 5.00
88 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13 5.00
89 INT49488 Gene_expression of mMCP-7 37 0.75 26.11 7.68 5.00
90 INT63365 Gene_expression of Spg21 21 0.65 12.9 7.37 5.00
91 INT73181 Gene_expression of Hspb1 24 0.78 15.84 7.31 5.00
92 INT111398 Localization of Mmp2 37 0.76 23.78 7.17 5.00
93 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13 5.00
94 INT181489 Localization of Spg21 16 0.12 10.89 6.84 5.00
95 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 5.00
96 INT213769 Binding of Spg21 18 0.03 7.96 6.77 5.00
97 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 5.00
98 INT108260 Positive_regulation of Par2 20 0.54 10.77 5.94 5.00
99 INT128406 Gene_expression of Pax1 11 0.60 7.18 5.91 5.00
100 INT118388 Localization of Nfe2l2 40 0.81 9.59 5.89 5.00
101 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 5.00
102 INT126177 Positive_regulation of Atf3 14 0.70 14.34 5.56 5.00
103 INT22839 Gene_expression of F2 31 0.74 15.53 5.56 5.00
104 INT111470 Positive_regulation of EPRS 18 0.44 11.42 5.29 5.00
105 INT159819 Gene_expression of F2rl3 5 0.45 5.53 5.24 5.00
106 INT111100 Gene_expression of Dusp1 18 0.76 14.81 5.21 5.00
107 INT20650 Positive_regulation of F2 26 0.69 15.49 5.08 5.00
108 INT10504 Localization of Pla2g1b 18 0.65 8.19 5.05 5.00
109 INT143234 Gene_expression of Nfkbia 10 0.62 5.2 5.02 5.00
110 INT94103 Gene_expression of EPRS 13 0.54 11.47 4.99 5.00
111 INT181350 Gene_expression of Ccl7 12 0.61 14.25 4.87 5.00
112 INT4146 Binding of SHBG 49 0.47 31 4.71 5.00
113 INT87210 Positive_regulation of Nfkbia 9 0.61 3.89 4.35 5.00
114 INT117495 Gene_expression of Pars2 13 0.38 7.93 4.24 5.00
115 INT149259 Gene_expression of RCT 38 0.67 15.73 3.87 5.00
116 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84 5.00
117 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83 5.00
118 INT98944 Gene_expression of ACTA2 14 0.59 11 3.7 5.00
119 INT170182 Negative_regulation of SULT2A1 14 0.34 11.47 3.63 5.00
120 INT1683 Gene_expression of Cux1 20 0.58 6.29 3.59 5.00
121 INT25990 Positive_regulation of Pla2g5 11 0.69 4.93 3.32 5.00
122 INT111099 Positive_regulation of Dusp1 11 0.68 7.62 3.18 5.00
123 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16 5.00
124 INT47011 Positive_regulation of Gusb 14 0.44 8.93 2.87 5.00
125 INT60339 Gene_expression of CYP21A2 8 0.66 4.04 2.77 5.00
126 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68 5.00
127 INT49808 Localization of tryptase 11 0.78 8.74 2.67 5.00
128 INT82653 Regulation of F2r 8 0.36 3.78 2.62 5.00
129 INT1586 Regulation of Binding of POMC 7 0.45 1.14 2.61 5.00
130 INT15606 Localization of FSHB 24 0.78 9.16 2.49 5.00
131 INT15604 Gene_expression of FSHB 30 0.56 9.7 2.45 5.00
132 INT127549 Gene_expression of Marcksl1 6 0.70 1.95 2.42 5.00
133 INT9188 Localization of HBG1 12 0.75 8.14 2.24 5.00
134 INT207082 Positive_regulation of Pars2 10 0.14 5.45 2.22 5.00
135 INT92316 Gene_expression of Plaur 30 0.61 22.06 2.21 5.00
136 INT82652 Negative_regulation of F2r 4 0.37 3.5 2.19 5.00
137 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17 5.00
138 INT213788 Gene_expression of Tfeb 18 0.66 7.9 2.07 5.00
139 INT145650 Localization of PLA2G6 15 0.76 8.87 2.06 5.00
140 INT47303 Regulation of Ctsl 10 0.56 2.64 2.04 5.00
141 INT155833 Gene_expression of Cma1 9 0.58 15.28 2.04 5.00
142 INT176173 Positive_regulation of Nr1h2 19 0.52 10.95 1.88 5.00
143 INT122378 Positive_regulation of Pla2g6 7 0.41 3.02 1.85 5.00
144 INT55924 Negative_regulation of IGKV2-30 3 0.07 2.26 1.8 5.00
145 INT99444 Positive_regulation of Proc 15 0.45 9.18 1.75 5.00
146 INT157762 Localization of EPRS 6 0.60 5.29 1.73 5.00
147 INT82918 Binding of AMBP 23 0.39 23.31 1.71 5.00
148 INT100375 Gene_expression of Vhl 14 0.15 22.3 1.69 5.00
149 INT207100 Gene_expression of Ptpn1 13 0.73 8.13 1.68 5.00
150 INT129053 Regulation of EPRS 3 0.17 2.79 1.6 5.00
151 INT156231 Binding of F2r 9 0.23 3.78 1.57 5.00
152 INT50077 Gene_expression of Myb 21 0.66 7.68 1.54 5.00
153 INT64233 Regulation of Trp53 35 0.62 27.11 1.53 5.00
154 INT207092 Localization of Dusp1 6 0.70 4.7 1.51 5.00
155 INT22836 Regulation of F2 9 0.59 2.3 1.49 5.00
156 INT190610 Gene_expression of Tceanc 19 0.07 15.24 1.48 5.00
157 INT136459 Gene_expression of Sp3 6 0.64 1.97 1.47 5.00
158 INT158311 Positive_regulation of F2rl3 7 0.51 1.77 1.44 5.00
159 INT117148 Gene_expression of Eef1a1 6 0.07 2.32 1.42 5.00
160 INT87215 Localization of Nfkbia 5 0.69 1.64 1.39 5.00
161 INT213772 Positive_regulation of Tfeb 1 0.39 3.5 1.35 5.00
162 INT119880 Binding of Usf1 5 0.20 2.55 1.28 5.00
163 INT153757 Positive_regulation of Mitf 10 0.46 8.38 1.22 5.00
164 INT81776 Positive_regulation of F3 8 0.07 3.77 1.21 5.00
165 INT207134 Positive_regulation of tryptase 11 0.47 11.16 1.21 5.00
166 INT171848 Positive_regulation of Ctsa 8 0.27 5.24 1.13 5.00
167 INT16172 Protein_catabolism of Insrr 5 0.18 1.39 1.11 5.00
168 INT207091 Positive_regulation of Pawr 2 0.36 1.95 1.1 5.00
169 INT46734 Positive_regulation of Stub1 6 0.16 1.44 1.09 5.00
170 INT54137 Positive_regulation of Positive_regulation of Serpine1 4 0.70 0.79 1.06 5.00
171 INT71499 Localization of Hspb1 4 0.72 1.38 1.05 5.00
172 INT181401 Localization of Ccl7 2 0.59 1.33 1.04 5.00
173 INT207094 Localization of Par2 3 0.52 1.48 1.04 5.00
174 INT179583 Gene_expression of Lmo4 5 0.41 1.97 1.03 5.00
175 INT80305 Gene_expression of IGKV2-30 6 0.04 3.68 1.01 5.00
176 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
177 INT124198 Negative_regulation of Nfkbia 4 0.37 2.58 0.97 5.00
178 INT207080 Regulation of Pard3b 2 0.05 1.62 0.95 5.00
179 INT66673 Regulation of Pdia3 5 0.42 2.14 0.93 5.00
180 INT190591 Positive_regulation of Rest 3 0.37 2.52 0.92 5.00
181 INT195105 Negative_regulation of Gene_expression of F2r 3 0.37 1.41 0.91 5.00
182 INT166379 Gene_expression of Araf 11 0.49 5.2 0.9 5.00
183 INT174442 Positive_regulation of Gene_expression of tryptase 3 0.17 1.63 0.87 5.00
184 INT297531 Negative_regulation of Ece1 5 0.32 5.49 0.87 5.00
185 INT207070 Positive_regulation of Pard3b 2 0.03 1.48 0.86 5.00
186 INT109007 Positive_regulation of Ccnd1 23 0.53 9.5 0.86 5.00
187 INT207103 Positive_regulation of Positive_regulation of Pawr 2 0.36 1.45 0.85 5.00
188 INT196322 Binding of F2 18 0.15 7.74 0.83 5.00
189 INT37747 Localization of Gusb 4 0.69 1.91 0.82 5.00
190 INT190611 Gene_expression of Cnn1 13 0.56 5.87 0.75 5.00
191 INT184694 Gene_expression of Usf1 10 0.55 4.27 0.72 5.00
192 INT287087 Localization of EEC1 2 0.61 1.6 0.72 5.00
193 INT213782 Regulation of Spg21 2 0.03 1.41 0.66 5.00
194 INT160961 Gene_expression of Fth1 4 0.28 3.89 0.63 5.00
195 INT207075 Positive_regulation of Upk2 4 0.60 2.95 0.63 5.00
196 INT207089 Regulation of Negative_regulation of F2r 1 0.17 1.49 0.62 5.00
197 INT207098 Positive_regulation of Tnfaip3 2 0.39 2.49 0.59 5.00
198 INT103888 Gene_expression of Atf2 7 0.58 1.69 0.59 5.00
199 INT213774 Positive_regulation of Positive_regulation of Mitf 1 0.31 1.53 0.58 5.00
200 INT178222 Gene_expression of Yy1 5 0.57 2.06 0.56 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox