D:Virilism

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Androgenization, Virilization
Documents 67
Hot Single Events 34
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Virilism. They are ordered first by their relevance to Virilism and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT277803 Regulation of GNRH1 Regulation of CGA 1 0.00 0.61 0 83.56
2 INT25248 GNRH1 Regulation of CGA 4 0.30 1.22 0.62 82.36
3 INT270758 GNRHR Positive_regulation of Localization of FSHR 1 0.08 0.68 0 77.24
4 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 0.15 0.86 0.26 75.96
5 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 69.84
6 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
7 INT312726 AASS Positive_regulation of FGD1 1 0.02 0.08 0.24 5.00
8 INT232015 SERPING1 Negative_regulation of F12 2 0.24 1.19 0.12 5.00
9 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1 5.00
10 INT323043 Binding of CYP21A1P and HLA-DOA 1 0.04 1.48 0.06 5.00
11 INT323042 Binding of CYP21A2 and HLA-DOA 1 0.04 1.49 0.06 5.00
12 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05 5.00
13 INT327162 Binding of SERPING1 and F12 1 0.05 0.29 0.04 5.00
14 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0 5.00
15 INT294922 GH1 Positive_regulation of Gene_expression of GHRH 1 0.02 0.2 0 5.00
16 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0 5.00
17 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Virilism. They are ordered first by their pain relevance and then by number of times they were reported in Virilism. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT75678 Regulation of Gene_expression of Gnrh1 6 0.44 1.21 0.54 100.00
2 INT17621 Positive_regulation of Gene_expression of Gnrh1 5 0.70 2.59 0.24 99.74
3 INT10787 Gene_expression of Gnrh1 64 0.78 23.06 6.76 99.42
4 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 99.20
5 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 98.66
6 INT44942 Positive_regulation of Localization of HSD11B1 5 0.49 4.18 0.31 98.18
7 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 97.92
8 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 97.82
9 INT8667 Localization of HSD11B1 22 0.73 22.74 1.25 97.82
10 INT17620 Positive_regulation of Gnrh1 23 0.70 9.77 3.79 97.80
11 INT105914 Negative_regulation of Positive_regulation of Gnrh1 2 0.43 0.1 0.33 97.80
12 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98 95.96
13 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 95.96
14 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1 95.96
15 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 94.80
16 INT62061 Gene_expression of TRGC1 32 0.69 17.43 3.37 94.80
17 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 94.76
18 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 93.96
19 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57 93.76
20 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 93.40
21 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 92.48
22 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 90.80
23 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 90.52
24 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 90.52
25 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58 90.52
26 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 90.36
27 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 90.12
28 INT228507 Positive_regulation of Gene_expression of Krt7 2 0.63 2.82 0 88.76
29 INT78281 Gene_expression of Krt7 28 0.70 26.77 0.97 88.48
30 INT4146 Binding of SHBG 49 0.47 31 4.71 86.96
31 INT99091 Regulation of AR 70 0.45 31.68 5.05 84.96
32 INT416 Regulation of LH 253 0.62 31.48 125.55 84.24
33 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 83.44
34 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 80.40
35 INT63238 Gene_expression of Mt1 27 0.65 10.86 2.53 79.96
36 INT43489 Gene_expression of Mtnr1a 5 0.20 0.97 0.73 79.96
37 INT32962 Positive_regulation of Localization of GNRHR 3 0.41 0.59 0.49 78.32
38 INT661 Gene_expression of REN 100 0.78 48.21 11.36 77.84
39 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 77.76
40 INT15607 Localization of GNRHR 14 0.62 7.56 2.3 77.76
41 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 77.52
42 INT1045 Localization of LH 1211 0.81 87.04 456.25 76.40
43 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 76.40
44 INT2159 Regulation of Localization of Gnrh1 200 0.62 13.28 99.07 76.40
45 INT546 Binding of ALB 311 0.48 85.98 60.14 75.28
46 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 75.00
47 INT1044 Negative_regulation of Localization of LH 358 0.59 25.95 151.31 75.00
48 INT1046 Gene_expression of LH 180 0.77 29.75 66.87 75.00
49 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 75.00
50 INT167717 Gene_expression of Gnrhr 5 0.55 2.49 0.69 75.00
51 INT91420 Negative_regulation of Gene_expression of Gnrh1 5 0.43 0.07 0.32 75.00
52 INT912 Localization of FSHR 91 0.79 23.61 15.58 74.56
53 INT1793 Localization of CGA 379 0.81 67.38 114.69 74.56
54 INT920 Localization of PLOD1 223 0.81 42.25 78.7 74.56
55 INT127273 Gene_expression of AMH 24 0.78 9.53 0.47 71.92
56 INT74871 Negative_regulation of Gene_expression of Mt1 3 0.26 1.8 0.48 69.88
57 INT425 Localization of PRL 455 0.81 189.64 144.8 68.24
58 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 66.44
59 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 65.64
60 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21 65.56
61 INT231587 Regulation of SBDS 5 0.16 1.1 0.93 65.56
62 INT35366 Binding of AR 87 0.47 30.52 8.9 65.52
63 INT312735 Localization of AASS 1 0.24 0.73 0 63.72
64 INT1530 Regulation of Gh 382 0.61 115.96 112.47 62.40
65 INT8916 Regulation of Igf1 45 0.60 13.06 5.81 61.20
66 INT19635 Localization of SHBG 7 0.78 2.83 1.29 60.16
67 INT115423 Gene_expression of Men1 4 0.47 14.08 0.64 60.00
68 INT156130 Binding of SERPING1 29 0.42 26.16 2.52 57.28
69 INT55924 Negative_regulation of IGKV2-30 3 0.07 2.26 1.8 56.96
70 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 55.76
71 INT319126 Negative_regulation of Gene_expression of STS 7 0.07 0.83 0.03 54.16
72 INT59194 Gene_expression of STS 18 0.59 6.74 1.89 53.60
73 INT70021 Localization of BCL2 23 0.74 21.6 1.09 50.64
74 INT106459 Negative_regulation of SLC10A4 4 0.24 1.08 1.06 50.64
75 INT161382 Localization of KRT20 25 0.61 12.97 2.13 50.12
76 INT186142 Gene_expression of Ghrh 45 0.66 34.04 6.94 50.00
77 INT34306 Localization of Gnrh1 43 0.81 4.86 6 50.00
78 INT187005 Positive_regulation of Gene_expression of Ghrh 9 0.48 8.02 0.29 50.00
79 INT308431 Gene_expression of CNC 1 0.01 2.84 0.18 46.08
80 INT11488 Negative_regulation of KLK1 15 0.57 9.92 3.06 44.92
81 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 43.76
82 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 43.56
83 INT316318 Phosphorylation of SERPING1 2 0.81 1.7 0.13 43.28
84 INT314336 Positive_regulation of Negative_regulation of TRGC1 2 0.41 2.23 0.21 33.52
85 INT78429 Positive_regulation of TRGC1 11 0.44 4.6 2.1 32.72
86 INT114091 Negative_regulation of Aip 6 0.48 4.16 1.3 32.48
87 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 31.20
88 INT316316 Negative_regulation of Binding of F12 1 0.18 1.1 0.12 29.16
89 INT77164 Binding of F12 8 0.47 2.66 1.48 28.68
90 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 25.76
91 INT316317 Negative_regulation of Gene_expression of KLK1 1 0.41 1.04 0.12 25.76
92 INT26451 Gene_expression of KLK1 14 0.75 5.79 1.66 25.20
93 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 24.60
94 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 23.36
95 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 20.96
96 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 18.04
97 INT170182 Negative_regulation of SULT2A1 14 0.34 11.47 3.63 16.00
98 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 14.68
99 INT179300 Negative_regulation of TGFB1I1 1 0.06 1.92 0 14.28
100 INT252 Localization of GH1 529 0.80 227.4 122.05 13.72
101 INT7413 Positive_regulation of Localization of SST 37 0.69 5.64 13.94 11.92
102 INT397 Localization of SST 232 0.81 58.05 101.19 11.00
103 INT1893 Localization of Gh 1041 0.79 340.23 256.58 10.96
104 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 6.04
105 INT58571 Positive_regulation of ALDOB 6 0.49 5.63 0.53 6.04
106 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
107 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 5.00
108 INT695 Binding of POMC 304 0.48 56.66 126.85 5.00
109 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
110 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
111 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
112 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
113 INT7134 Localization of KNG1 127 0.79 65.73 67.97 5.00
114 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
115 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 5.00
116 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 5.00
117 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
118 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
119 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 5.00
120 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02 5.00
121 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 5.00
122 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
123 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 5.00
124 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
125 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
126 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
127 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 5.00
128 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3 5.00
129 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
130 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72 5.00
131 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 5.00
132 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 5.00
133 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
134 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 5.00
135 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
136 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 5.00
137 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
138 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 5.00
139 INT7113 Negative_regulation of Localization of CGA 71 0.51 17.7 23.42 5.00
140 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 5.00
141 INT917 Positive_regulation of Localization of PLOD1 51 0.69 8.53 22.87 5.00
142 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
143 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
144 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 5.00
145 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
146 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
147 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 5.00
148 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 5.00
149 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
150 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
151 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 5.00
152 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 5.00
153 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14 5.00
154 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
155 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 5.00
156 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 5.00
157 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
158 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
159 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
160 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47 5.00
161 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 5.00
162 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 5.00
163 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
164 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
165 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
166 INT1647 Negative_regulation of FSHR 54 0.45 13.44 8.87 5.00
167 INT34777 Localization of IGF1 82 0.80 42.68 8.62 5.00
168 INT13435 Positive_regulation of RTCA 31 0.60 7.19 8.5 5.00
169 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34 5.00
170 INT12292 Negative_regulation of Positive_regulation of GH1 22 0.58 5.02 8.28 5.00
171 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17 5.00
172 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13 5.00
173 INT26181 Positive_regulation of Negative_regulation of POMC 12 0.70 1.03 6.14 5.00
174 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 5.00
175 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
176 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92 5.00
177 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 5.00
178 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5 5.00
179 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 5.00
180 INT118124 Binding of USE1 24 0.16 16.64 5.44 5.00
181 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 5.00
182 INT121801 Binding of Aip 18 0.36 24.1 5.26 5.00
183 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75 5.00
184 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 5.00
185 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91 5.00
186 INT78023 Gene_expression of DDX41 13 0.65 23.55 3.84 5.00
187 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83 5.00
188 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 5.00
189 INT545 Binding of GC 15 0.45 10.74 3.47 5.00
190 INT15609 Positive_regulation of Gene_expression of GNRH1 17 0.49 5.15 3.34 5.00
191 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 5.00
192 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99 5.00
193 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9 5.00
194 INT25031 Negative_regulation of Gene_expression of PLOD1 14 0.54 3.86 2.89 5.00
195 INT158083 Gene_expression of FGD1 24 0.67 6.82 2.83 5.00
196 INT60339 Gene_expression of CYP21A2 8 0.66 4.04 2.77 5.00
197 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65 5.00
198 INT1586 Regulation of Binding of POMC 7 0.45 1.14 2.61 5.00
199 INT39518 Negative_regulation of HBN1 66 0.09 37.54 2.58 5.00
200 INT15606 Localization of FSHB 24 0.78 9.16 2.49 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox