D:Visna

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Disease Term
Synonyms Encephalomyelitides Ovine, ENCEPHALOMYELITIS OVINE, Ovine Encephalomyelitides, Ovine Encephalomyelitis, Visnas
Documents 7
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Visna. They are ordered first by their relevance to Visna and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT228501 Binding of AAVS1 and Fgfr1 1 0.01 0.57 0.07 42.20
2 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99 5.00
3 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99 5.00
4 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98 5.00
5 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73 5.00
6 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72 5.00
7 INT228497 Il4 Regulation of Ncoa5 1 0.01 1.24 0.57 5.00
8 INT228500 Fadd Positive_regulation of FAS 1 0.14 1.12 0.28 5.00
9 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0 5.00
10 INT211779 Binding of EIF4G1 and NTSR1 1 0.02 0 0 5.00
11 INT211781 Binding of NTSR1 and RDBP 1 0.00 0.42 0 5.00
12 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0 5.00
13 INT211777 Binding of NTSR1 and PTBP1 1 0.03 0.82 0 5.00
14 INT353799 Binding of Cd320 and Hdl1 1 0.03 0.83 0 5.00
15 INT211780 Binding of AHSA1 and PLVAP 1 0.01 0 0 5.00
16 INT353802 Binding of APOE and Apob 1 0.05 0.83 0 5.00
17 INT211776 Binding of PTBP2 and PLVAP 1 0.05 0.43 0 5.00
18 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0 5.00
19 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0 5.00
20 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0 5.00
21 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0 5.00
22 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0 5.00
23 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0 5.00
24 INT211778 Binding of PCBP1 and PLVAP 1 0.07 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Visna. They are ordered first by their pain relevance and then by number of times they were reported in Visna. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT193582 Gene_expression of PVR 21 0.58 14 2.39 98.24
2 INT189923 Binding of Pol 5 0.20 2.09 0.04 91.16
3 INT192841 Binding of Mela 9 0.43 4.29 0.58 90.80
4 INT68285 Gene_expression of SERPINB3 24 0.75 25.4 0.45 90.08
5 INT68288 Positive_regulation of SERPINB3 14 0.51 16.87 0.41 89.60
6 INT353774 Protein_catabolism of Lvs 1 0.12 0.92 0.04 82.76
7 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74 75.20
8 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 72.96
9 INT314619 Gene_expression of ZGLP1 4 0.29 3.75 0.1 72.76
10 INT345482 Positive_regulation of Gene_expression of ZGLP1 1 0.03 1.01 0 72.76
11 INT88390 Gene_expression of LGALS4 27 0.69 12.28 4.15 72.24
12 INT237179 Positive_regulation of Gene_expression of LGALS4 6 0.44 2.46 0.97 72.24
13 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 64.32
14 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 60.96
15 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 59.60
16 INT105669 Positive_regulation of Gene_expression of AAVS1 20 0.49 9.02 2.06 54.08
17 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 54.08
18 INT136831 Gene_expression of Nodal 6 0.22 5.68 0.97 54.08
19 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 49.00
20 INT345480 Binding of CYP7A1 1 0.29 0 0.03 18.08
21 INT195817 Gene_expression of ipv 28 0.58 31.04 1.86 17.88
22 INT68286 Regulation of SERPINB3 10 0.60 3.07 0.06 13.88
23 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
24 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
25 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
26 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
27 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
28 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
29 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
30 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
31 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 5.00
32 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 5.00
33 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
34 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 5.00
35 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
36 INT97596 Localization of S100a8 94 0.78 90.69 40.41 5.00
37 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 5.00
38 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 5.00
39 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 5.00
40 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 5.00
41 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
42 INT90792 Localization of Il10 144 0.80 87.88 30.03 5.00
43 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
44 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 5.00
45 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 5.00
46 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 5.00
47 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 5.00
48 INT170313 Gene_expression of Mmp1a 50 0.65 38.53 21.36 5.00
49 INT20379 Localization of Il4 85 0.73 51.22 20.55 5.00
50 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 5.00
51 INT33542 Gene_expression of Il1rn 41 0.76 32.47 18.08 5.00
52 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87 5.00
53 INT103757 Negative_regulation of Il12a 37 0.55 21.62 16.38 5.00
54 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 5.00
55 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 5.00
56 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4 5.00
57 INT142464 Gene_expression of Socs3 58 0.77 52.04 15.34 5.00
58 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
59 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
60 INT25076 Negative_regulation of Gene_expression of Il1 41 0.52 30.58 13.85 5.00
61 INT34904 Negative_regulation of Gtf3a 48 0.15 38.88 13.73 5.00
62 INT173505 Localization of Hand2 63 0.57 45.32 13.66 5.00
63 INT152729 Negative_regulation of Gene_expression of S100a8 33 0.42 32.25 13.64 5.00
64 INT20378 Localization of Hand1 53 0.71 41.96 13.31 5.00
65 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3 5.00
66 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 5.00
67 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 5.00
68 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39 5.00
69 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5 5.00
70 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76 5.00
71 INT140338 Negative_regulation of Gene_expression of Il17a 34 0.46 23.82 9.87 5.00
72 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75 5.00
73 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32 5.00
74 INT156874 Positive_regulation of Gene_expression of S100a8 26 0.49 32.8 8.99 5.00
75 INT178174 Gene_expression of Tnfsf10 78 0.76 56.83 8.64 5.00
76 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51 5.00
77 INT142462 Positive_regulation of Gene_expression of Socs3 23 0.68 23.27 8.27 5.00
78 INT177759 Negative_regulation of IFN1@ 51 0.57 31.81 7.76 5.00
79 INT153794 Gene_expression of Ctsk 51 0.77 24.99 7.28 5.00
80 INT228469 Negative_regulation of Il17a 19 0.54 18.76 6.43 5.00
81 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 5.00
82 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23 5.00
83 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 5.00
84 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 5.00
85 INT104547 Negative_regulation of Il18 24 0.59 17.89 6.01 5.00
86 INT115947 Regulation of Il17a 17 0.37 14.26 5.97 5.00
87 INT68661 Positive_regulation of NTSR1 11 0.69 9.6 5.91 5.00
88 INT80033 Binding of FAS 37 0.48 41.19 5.67 5.00
89 INT96234 Localization of Il13 11 0.62 10.94 5.48 5.00
90 INT120511 Positive_regulation of Gene_expression of Cat 26 0.69 19.82 5.2 5.00
91 INT156850 Binding of VDR 40 0.47 24.86 4.87 5.00
92 INT104549 Localization of Il18 16 0.78 13.01 4.64 5.00
93 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54 5.00
94 INT47298 Localization of Ctsl 13 0.79 3.77 4.08 5.00
95 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 5.00
96 INT228465 Positive_regulation of Timp2 4 0.64 6.29 3.54 5.00
97 INT188406 Binding of Fasl 19 0.44 24.67 3.17 5.00
98 INT209561 Negative_regulation of Ncoa5 2 0.05 6.88 3.14 5.00
99 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 5.00
100 INT170324 Negative_regulation of Gene_expression of Mmp1a 8 0.13 6.28 2.94 5.00
101 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91 5.00
102 INT157188 Positive_regulation of Gene_expression of Il13 3 0.05 4.94 2.79 5.00
103 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77 5.00
104 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73 5.00
105 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
106 INT104476 Protein_catabolism of Timp1 6 0.41 5.75 2.61 5.00
107 INT68781 Negative_regulation of TFAM 15 0.58 10.01 2.42 5.00
108 INT192541 Gene_expression of Tg(Foxn1)E1Hon 20 0.20 8.98 2.4 5.00
109 INT68658 Gene_expression of NTSR1 17 0.77 7.88 2.32 5.00
110 INT146660 Negative_regulation of Ctsk 9 0.43 6.01 2.07 5.00
111 INT209559 Regulation of Ncoa5 1 0.03 4.37 2 5.00
112 INT122924 Binding of ipv 27 0.42 31.81 1.99 5.00
113 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97 5.00
114 INT90219 Gene_expression of Lgals1 6 0.20 3.47 1.94 5.00
115 INT209564 Positive_regulation of Ncoa5 6 0.05 4.72 1.89 5.00
116 INT209567 Gene_expression of Ncoa5 4 0.05 4.81 1.78 5.00
117 INT36529 Gene_expression of Mela 39 0.69 12.05 1.73 5.00
118 INT204763 Transcription of S100a8 8 0.69 6.22 1.69 5.00
119 INT98788 Negative_regulation of EPHB1 11 0.37 3.65 1.64 5.00
120 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57 5.00
121 INT164410 Negative_regulation of Col2a1 4 0.39 3.75 1.53 5.00
122 INT95226 Gene_expression of AHSA1 5 0.49 3.62 1.52 5.00
123 INT90218 Localization of Lgals1 3 0.18 1.77 1.51 5.00
124 INT79357 Binding of ERVW-1 32 0.43 16.06 1.35 5.00
125 INT154098 Binding of NTSR1 3 0.47 1.18 1.28 5.00
126 INT53261 Gene_expression of exf 5 0.07 4.93 1.24 5.00
127 INT108559 Gene_expression of Pol 46 0.45 30.07 1.14 5.00
128 INT47305 Positive_regulation of Gene_expression of Ctsl 5 0.59 2.06 1.12 5.00
129 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07 5.00
130 INT139064 Binding of Cd80 3 0.35 1.64 1.07 5.00
131 INT184020 Localization of Socs3 3 0.75 4.05 1.06 5.00
132 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97 5.00
133 INT124975 Gene_expression of Tnfrsf22 2 0.41 3.57 0.97 5.00
134 INT209423 Negative_regulation of Gene_expression of Ctsk 4 0.41 2.4 0.96 5.00
135 INT139176 Gene_expression of Fadd 5 0.51 5.26 0.92 5.00
136 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9 5.00
137 INT182968 Positive_regulation of Gene_expression of VDR 22 0.58 15.22 0.89 5.00
138 INT10828 Regulation of Apob 7 0.39 7.55 0.83 5.00
139 INT209562 Negative_regulation of Gene_expression of Ncoa5 2 0.03 1.75 0.79 5.00
140 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78 5.00
141 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76 5.00
142 INT228474 Regulation of Gene_expression of Tnfsf10 3 0.44 3.81 0.75 5.00
143 INT228470 Phosphorylation of Il1rap 1 0.11 1.34 0.7 5.00
144 INT209563 Negative_regulation of Positive_regulation of Ncoa5 2 0.03 1.88 0.68 5.00
145 INT142802 Binding of Ldlr 8 0.47 5.08 0.65 5.00
146 INT211782 Localization of Ambp 2 0.26 2.12 0.64 5.00
147 INT164957 Regulation of Gene_expression of Hras1 8 0.04 4.4 0.64 5.00
148 INT228476 Binding of Ctla4 4 0.36 3.03 0.62 5.00
149 INT17810 Localization of Fn1 4 0.55 2.3 0.62 5.00
150 INT133589 Negative_regulation of Pol 6 0.25 2.84 0.61 5.00
151 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6 5.00
152 INT211808 Localization of NFKB2 4 0.19 4.17 0.58 5.00
153 INT61972 Negative_regulation of TBP 5 0.32 3.56 0.53 5.00
154 INT144701 Gene_expression of Cdkn2a 15 0.75 8.42 0.53 5.00
155 INT212966 Negative_regulation of Gene_expression of Hdl1 8 0.27 10.98 0.49 5.00
156 INT211807 Binding of PTBP1 11 0.31 6.09 0.45 5.00
157 INT198884 Gene_expression of Vldlr 13 0.70 2.41 0.44 5.00
158 INT238793 Gene_expression of Cbl 6 0.03 3.01 0.43 5.00
159 INT115212 Gene_expression of PLVAP 2 0.30 1.1 0.38 5.00
160 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37 5.00
161 INT46843 Binding of Trf 10 0.47 3.45 0.35 5.00
162 INT228475 Regulation of Gene_expression of Tnfrsf22 1 0.01 0.95 0.34 5.00
163 INT1626 Binding of Cog1 8 0.21 7.86 0.34 5.00
164 INT232235 Negative_regulation of Gene_expression of Ldlr 3 0.42 3.13 0.34 5.00
165 INT211814 Transcription of polymerase 3 0.04 0.97 0.33 5.00
166 INT196323 Localization of Cdkn2a 8 0.73 9.1 0.32 5.00
167 INT187410 Localization of Cd320 14 0.78 9.03 0.31 5.00
168 INT211815 Gene_expression of CSDE1 4 0.27 2.34 0.29 5.00
169 INT228468 Localization of Csk 1 0.12 0.79 0.29 5.00
170 INT228467 Positive_regulation of Gene_expression of Csk 1 0.08 0.79 0.29 5.00
171 INT228466 Positive_regulation of Gene_expression of Igkv1-117 1 0.04 0.78 0.29 5.00
172 INT228473 Positive_regulation of Localization of Csk 1 0.08 0.79 0.29 5.00
173 INT228472 Gene_expression of Igkv1-117 1 0.05 0.78 0.29 5.00
174 INT228477 Positive_regulation of Gene_expression of Cdkn2a 2 0.11 1.3 0.29 5.00
175 INT228471 Gene_expression of Csk 1 0.11 0.79 0.29 5.00
176 INT9054 Negative_regulation of Positive_regulation of Cog1 3 0.08 1.38 0.28 5.00
177 INT198492 Localization of Sumo1 3 0.24 0 0.21 5.00
178 INT333881 Gene_expression of GAG 2 0.75 0.4 0.2 5.00
179 INT274731 Binding of EPHB1 3 0.22 0.76 0.2 5.00
180 INT252222 Regulation of Ldlr 5 0.34 4.3 0.19 5.00
181 INT211839 Binding of EIF4E 8 0.36 0.79 0.18 5.00
182 INT211827 Localization of PVR 3 0.61 1.33 0.13 5.00
183 INT203827 Localization of Apob 3 0.32 1.81 0.13 5.00
184 INT198900 Positive_regulation of Vldlr 3 0.26 1.44 0.12 5.00
185 INT114901 Binding of TBP 6 0.17 2.45 0.11 5.00
186 INT211821 Binding of PLXNC1 2 0.01 0.57 0.09 5.00
187 INT261601 Binding of Emr1 2 0.02 1.34 0.08 5.00
188 INT211806 Gene_expression of PLXNC1 4 0.63 2.95 0.07 5.00
189 INT211835 Binding of SRSF3 1 0.19 0.14 0.07 5.00
190 INT211809 Localization of NTSR1 1 0.10 0.63 0.07 5.00
191 INT293307 Regulation of Gene_expression of Ldlr 3 0.19 2.77 0.07 5.00
192 INT314131 Positive_regulation of Prdm16 2 0.67 1.56 0.06 5.00
193 INT240615 Binding of Apob 2 0.07 0.85 0.04 5.00
194 INT211830 Binding of PVR 3 0.32 2.26 0.03 5.00
195 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03 5.00
196 INT353783 Positive_regulation of Gene_expression of Vldlr 1 0.28 0.51 0 5.00
197 INT211829 Protein_catabolism of TBP 1 0.17 0.09 0 5.00
198 INT211820 Negative_regulation of PLVAP 1 0.17 0.8 0 5.00
199 INT353785 Negative_regulation of Gene_expression of Gag protein 1 0.57 0 0 5.00
200 INT211826 Binding of PCBP1 1 0.21 0 0 5.00
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