D:Vitamin Deficiency

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Disease Term
Synonyms AVITAMINOSES, Avitaminosis, DEFICIENCIES VITAMIN, Deficiency Vitamin, Vitamin A Deficiency, Vitamin B Deficiency, Vitamin B12 Deficiency, VITAMIN C DEFICIENCY, VITAMIN D DEFICIENCY, Vitamin Deficiencies, Vitamin Deficient
Documents 109
Hot Single Events 23
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Vitamin Deficiency. They are ordered first by their relevance to Vitamin Deficiency and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78 5.00
2 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55 5.00
3 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 0.08 1.14 0.37 5.00
4 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35 5.00
5 INT229332 BAS Negative_regulation of Pck1 1 0.01 0.2 0.28 5.00
6 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22 5.00
7 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22 5.00
8 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16 5.00
9 INT214480 SELPLG Negative_regulation of Positive_regulation of NFKB1 1 0.00 0.6 0.14 5.00
10 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13 5.00
11 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
12 INT229287 BAS Negative_regulation of CRP 1 0.04 0.36 0.11 5.00
13 INT352555 DKK1 Positive_regulation of Wnt2 1 0.01 0.25 0.1 5.00
14 INT229286 BAS Negative_regulation of FXR1 1 0.02 0.55 0.09 5.00
15 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
16 INT229274 BAS Positive_regulation of BAS Negative_regulation of FXR1 1 0.00 0.55 0.09 5.00
17 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
18 INT321867 TNFRSF11B Negative_regulation of TNFSF11 1 0.00 0.85 0.08 5.00
19 INT321868 Binding of TNFRSF11B and Negative_regulation of TNFSF11 1 0.00 0.91 0.08 5.00
20 INT229330 Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK 1 0.01 0.62 0.07 5.00
21 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07 5.00
22 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
23 INT229291 BAS Positive_regulation of HSD11B1 1 0.09 0.22 0.06 5.00
24 INT229288 Binding of FXR1 and BAS 1 0.01 0.59 0.05 5.00
25 INT229329 NR0B2 Negative_regulation of Nr1h2 1 0.03 0.58 0.05 5.00
26 INT229285 BAS Negative_regulation of FGF19 1 0.07 0.33 0.05 5.00
27 INT229275 Binding of FXR1 and BAS Negative_regulation of FXR1 1 0.00 0.59 0.05 5.00
28 INT229331 Binding of FXR1 and Nr1h2 1 0.02 0.61 0.05 5.00
29 INT229293 Positive_regulation of FXR1 Positive_regulation of Gene_expression of NR0B2 1 0.02 0.59 0.04 5.00
30 INT269759 PTH Positive_regulation of DMD 2 0.06 0.37 0.03 5.00
31 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
32 INT144761 Binding of INSR and Insr 1 0.05 0 0 5.00
33 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
34 INT144754 Negative_regulation of Binding of Insr and Slc2a2 1 0.01 0 0 5.00
35 INT273482 Binding of CYSLTR1 and USE1 1 0.00 0.77 0 5.00
36 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0 5.00
37 INT273480 Binding of EPO and RNASEL 1 0.08 0.77 0 5.00
38 INT239407 Binding of MTTP and PADI1 1 0.23 0.5 0 5.00
39 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0 5.00
40 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0 5.00
41 INT144753 Binding of Insr and Slc2a2 1 0.01 0 0 5.00
42 INT144762 Negative_regulation of Binding of INSR and Insr 1 0.06 0 0 5.00
43 INT273481 Binding of RNASEL and USE1 1 0.02 0.76 0 5.00
44 INT273483 Binding of RNASEL and CYSLTR1 1 0.00 0.78 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Vitamin Deficiency. They are ordered first by their pain relevance and then by number of times they were reported in Vitamin Deficiency. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT194794 Binding of TTPA 7 0.08 2.56 0.57 100.00
2 INT199661 Negative_regulation of TTPA 2 0.04 1.84 0 100.00
3 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 99.12
4 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.00
5 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5 98.60
6 INT156850 Binding of VDR 40 0.47 24.86 4.87 97.36
7 INT70860 Binding of SNRPB 17 0.35 7 1.46 97.24
8 INT228977 Binding of SERPINA2 1 0.25 5.42 0.35 96.80
9 INT106020 Transcription of EPO 8 0.71 9.34 0.6 95.16
10 INT273491 Negative_regulation of Transcription of EPO 1 0.58 4.29 0.2 95.16
11 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 95.04
12 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 94.92
13 INT661 Gene_expression of REN 100 0.78 48.21 11.36 94.92
14 INT320987 Transcription of Gc 1 0.07 0.36 0 91.12
15 INT294932 Negative_regulation of Gc 6 0.17 3.38 0.71 87.36
16 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 85.12
17 INT287118 Negative_regulation of Gene_expression of VDR 3 0.36 3.53 0.66 85.04
18 INT189390 Positive_regulation of MT1F 5 0.08 0.85 0.14 84.00
19 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 83.92
20 INT50080 Binding of APOE 38 0.45 29.61 2.67 83.52
21 INT22083 Regulation of Pth 55 0.62 22.32 8.9 81.36
22 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 81.36
23 INT239411 Localization of APOB 10 0.76 5.71 0.04 80.48
24 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 77.92
25 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39 76.84
26 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95 76.84
27 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 76.84
28 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 73.68
29 INT177832 Positive_regulation of Gene_expression of MT1F 5 0.28 2.75 1.05 73.68
30 INT109594 Positive_regulation of ABL1 10 0.49 7.19 0.05 65.40
31 INT308240 Gene_expression of Prm3 1 0.06 3.69 0.09 64.88
32 INT308239 Negative_regulation of Gene_expression of Prm3 1 0.04 1.12 0 64.88
33 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 63.56
34 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17 63.48
35 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 61.32
36 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 59.72
37 INT63505 Negative_regulation of F2 18 0.57 7.4 2.2 57.56
38 INT14486 Localization of Mbp 23 0.74 11.24 6.14 54.60
39 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 52.32
40 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 51.84
41 INT102638 Regulation of VDR 21 0.44 9.92 2.54 50.80
42 INT119892 Gene_expression of Cftr 54 0.77 23.76 9.73 50.00
43 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4 50.00
44 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59 50.00
45 INT67138 Gene_expression of Gc 19 0.31 17.11 4.1 50.00
46 INT89113 Regulation of Cftr 11 0.62 6.83 4.01 50.00
47 INT147213 Negative_regulation of Gene_expression of Dbp 5 0.34 2.88 1.16 50.00
48 INT13826 Positive_regulation of Negative_regulation of Dbp 5 0.42 2.19 0.74 50.00
49 INT294931 Positive_regulation of Negative_regulation of Gc 1 0.05 0.62 0.26 50.00
50 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 48.76
51 INT126734 Positive_regulation of MDM2 8 0.49 5.56 0 48.76
52 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 46.20
53 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 45.88
54 INT140637 Negative_regulation of IFI27 11 0.40 9.48 0.69 45.88
55 INT150165 Gene_expression of MTTP 21 0.75 10.1 0.73 45.44
56 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 40.24
57 INT7678 Localization of Alb 142 0.81 80.93 22.49 39.68
58 INT19847 Positive_regulation of Localization of Alb 21 0.70 13.89 4.16 39.68
59 INT11567 Negative_regulation of Localization of Alb 17 0.48 7.69 1.56 39.68
60 INT246552 Transcription of Fmr1 11 0.72 6.72 0.71 39.60
61 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 33.44
62 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 30.12
63 INT251 Regulation of INS 398 0.62 232.47 55.04 28.36
64 INT22500 Negative_regulation of Pth 6 0.43 3.41 2.83 27.52
65 INT188754 Localization of AGRP 15 0.74 8.88 0.6 26.24
66 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 25.84
67 INT101693 Gene_expression of Ggt1 2 0.65 4.92 0.81 25.12
68 INT246551 Negative_regulation of Serpinb12 1 0.01 2.57 0.17 23.52
69 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 20.88
70 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 20.32
71 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 17.08
72 INT50444 Negative_regulation of Gene_expression of Alb 11 0.39 7.63 1.06 9.84
73 INT196321 Negative_regulation of Gene_expression of F2 2 0.17 1.48 0.04 9.84
74 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 8.96
75 INT22839 Gene_expression of F2 31 0.74 15.53 5.56 8.64
76 INT227413 Gene_expression of DLAT 12 0.44 13.21 1.36 8.32
77 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
78 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
79 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
80 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
81 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
82 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
83 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
84 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
85 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 5.00
86 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
87 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
88 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
89 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5 5.00
90 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 5.00
91 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
92 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23 5.00
93 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59 5.00
94 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
95 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
96 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
97 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 5.00
98 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 5.00
99 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
100 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
101 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 5.00
102 INT8691 Localization of Insr 85 0.80 9.27 30.32 5.00
103 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 5.00
104 INT5300 Regulation of Insr 54 0.60 11.33 29.26 5.00
105 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
106 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
107 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
108 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
109 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
110 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
111 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
112 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 5.00
113 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
114 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 5.00
115 INT14306 Positive_regulation of Gal 36 0.70 21.66 18.51 5.00
116 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 5.00
117 INT7580 Positive_regulation of Mbp 54 0.70 23.37 17.14 5.00
118 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
119 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
120 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
121 INT106745 Localization of CRP 65 0.81 66.44 15.21 5.00
122 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
123 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 5.00
124 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
125 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
126 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
127 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
128 INT7465 Negative_regulation of Mbp 53 0.58 19.12 13.27 5.00
129 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
130 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 5.00
131 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 5.00
132 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 5.00
133 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
134 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 5.00
135 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
136 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
137 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
138 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
139 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 5.00
140 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34 5.00
141 INT16404 Regulation of CD4 54 0.61 33.05 10.29 5.00
142 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
143 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 5.00
144 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 5.00
145 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14 5.00
146 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 5.00
147 INT17701 Gene_expression of PTHLH 103 0.78 64.23 8.85 5.00
148 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
149 INT51165 Binding of Gal 10 0.48 2.56 8.41 5.00
150 INT78320 Gene_expression of EPCAM 57 0.75 50.34 7.53 5.00
151 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 5.00
152 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 5.00
153 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02 5.00
154 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 5.00
155 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 5.00
156 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 5.00
157 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
158 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 5.00
159 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45 5.00
160 INT7464 Regulation of Mbp 25 0.62 6.62 6.43 5.00
161 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 5.00
162 INT11814 Positive_regulation of Alb 43 0.63 31.71 6.28 5.00
163 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 5.00
164 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 5.00
165 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 5.00
166 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 5.00
167 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 5.00
168 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 5.00
169 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 5.00
170 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 5.00
171 INT118124 Binding of USE1 24 0.16 16.64 5.44 5.00
172 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
173 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 5.00
174 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 5.00
175 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25 5.00
176 INT65135 Binding of CYP2C19 17 0.48 1.82 5.2 5.00
177 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 5.00
178 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 5.00
179 INT151102 Positive_regulation of CFTR 22 0.61 15.27 5.12 5.00
180 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 5.00
181 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86 5.00
182 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 5.00
183 INT2848 Localization of ABCA1 23 0.70 10.64 4.73 5.00
184 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61 5.00
185 INT169756 Binding of CFTR 9 0.35 9.65 4.55 5.00
186 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 5.00
187 INT108306 Positive_regulation of TNFRSF11B 28 0.60 12.74 4.46 5.00
188 INT8743 Positive_regulation of Gcg 19 0.65 10.63 4.43 5.00
189 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4 5.00
190 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 5.00
191 INT22145 Binding of Sugt1 16 0.13 8.31 4.37 5.00
192 INT24278 Gene_expression of FUT4 33 0.75 26.7 4.29 5.00
193 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 5.00
194 INT64157 Positive_regulation of EPCAM 11 0.44 9.09 4.24 5.00
195 INT51084 Binding of Insr 13 0.30 4.25 4.23 5.00
196 INT113282 Negative_regulation of TNFRSF11B 17 0.57 13.71 4.17 5.00
197 INT93016 Binding of TNFRSF11A 29 0.47 19.67 4.17 5.00
198 INT83035 Binding of INSR 16 0.47 9.29 4.11 5.00
199 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 5.00
200 INT151099 Negative_regulation of CFTR 12 0.59 10.28 3.79 5.00
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