D:Vohwinkel Syndrome

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Disease Term
Synonyms Disease Meleda, Hyperkeratosis Palmaris Et Plantaris, Keratoderma Hereditaria Mutilans, Keratoderma Palmoplantar, KERATODERMAS PALMOPLANTAR, Keratoses Palmoplantar, KERATOSIS PALMARIS ET PLANTARIS, Keratosis Palmoplantar, Meleda Disease, PALMOPLANTAR KERATODERMA, Palmoplantar Keratoderma Mutilans
Documents 26
Hot Single Events 9
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Vohwinkel Syndrome. They are ordered first by their relevance to Vohwinkel Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26 5.00
2 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26 5.00
3 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2 5.00
4 INT235014 Car2 Positive_regulation of DSP 1 0.06 0.28 0.2 5.00
5 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06 5.00
6 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05 5.00
7 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05 5.00
8 INT234990 Binding of Cish and Dsp 1 0.01 0.24 0.04 5.00
9 INT235003 Binding of NKS1 and Rdh2 1 0.00 0.18 0.04 5.00
10 INT234986 Binding of Rdh2 and Dsp 1 0.00 0.24 0.04 5.00
11 INT234994 Binding of NKS1 and Dsg3 1 0.00 0.5 0.04 5.00
12 INT235012 Binding of NKS1 and Dsp 1 0.00 0.24 0.04 5.00
13 INT234998 Binding of NKS1 and Cish 1 0.00 0.18 0.04 5.00
14 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03 5.00
15 INT234981 Binding of Dsg3 and Negative_regulation of Gsk3b 1 0.07 0.3 0.03 5.00
16 INT234984 Binding of Dsg3 and Positive_regulation of Akt1 1 0.03 0.32 0.03 5.00
17 INT234978 Binding of Dsg3 and Positive_regulation of Inppl1 1 0.00 0.32 0.03 5.00
18 INT234975 Binding of Dsg3 and Negative_regulation of Gsk3a 1 0.03 0.3 0.03 5.00
19 INT235004 Binding of PKP1 and Dsp 1 0.00 0.14 0 5.00
20 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0 5.00
21 INT234972 IgG Positive_regulation of Gene_expression of Dsg3 1 0.05 0.8 0 5.00
22 INT235002 Negative_regulation of Binding of DSG1 and Dsg3 1 0.13 1.08 0 5.00
23 INT235011 Ctnnd1 Positive_regulation of RAC1 1 0.00 0.07 0 5.00
24 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0 5.00
25 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0 5.00
26 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0 5.00
27 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0 5.00
28 INT234985 Binding of Dsg3 and Pitx3 1 0.00 0.3 0 5.00
29 INT234979 IgG Negative_regulation of Binding of Dsg3 1 0.06 1.59 0 5.00
30 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0 5.00
31 INT234970 Binding of Jup and Lat 1 0.01 0 0 5.00
32 INT235019 Binding of DSC1 and DSP 1 0.39 0.07 0 5.00
33 INT235018 Binding of DSP and GOPC 1 0.02 0.19 0 5.00
34 INT234997 Binding of DSG1 and Car2 1 0.03 0.1 0 5.00
35 INT235000 IgG Negative_regulation of DSG1 1 0.04 0.86 0 5.00
36 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0 5.00
37 INT234999 IgG Positive_regulation of Gene_expression of DSG1 1 0.05 0.8 0 5.00
38 INT235015 Binding of DSP and Dsp 1 0.02 0.25 0 5.00
39 INT192044 Binding of DSP and Jup 2 0.24 2.39 0 5.00
40 INT235008 Binding of DSG1 and Dsg3 1 0.11 4.82 0 5.00
41 INT234974 Binding of Lat and Dsp 1 0.00 0 0 5.00
42 INT234988 Negative_regulation of Binding of Dsg3 and IgG 1 0.04 0.83 0 5.00
43 INT234989 IgG Positive_regulation of Positive_regulation of Car2 1 0.01 0.98 0 5.00
44 INT234993 Binding of Car2 and Dsp 1 0.00 0 0 5.00
45 INT234966 Phosphorylation of Jup Regulation of Binding of DSP and Jup 1 0.03 0.49 0 5.00
46 INT234982 Binding of Jup and Pkp1 1 0.00 0 0 5.00
47 INT235001 Binding of PKP1 and Sergef 1 0.01 0.06 0 5.00
48 INT235021 PKP1 Regulation of CDC42EP5 1 0.00 0.06 0 5.00
49 INT234967 Binding of Dsg3 and IgG 1 0.03 0.83 0 5.00
50 INT235016 IgG Negative_regulation of Binding of DSG1 1 0.04 2.89 0 5.00
51 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Vohwinkel Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Vohwinkel Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT85624 Gene_expression of GJB1 5 0.78 3.03 0.93 96.28
2 INT98160 Binding of Slurp1 4 0.41 0.52 0.94 95.84
3 INT159758 Gene_expression of Slurp1 1 0.60 0.46 1.59 91.36
4 INT159759 Binding of Slurp1 1 0.35 0.15 0.15 90.16
5 INT159757 Binding of Pvrl1 1 0.07 0.15 0.15 90.16
6 INT159762 Localization of Slurp1 1 0.70 0.29 0.71 86.56
7 INT234867 Localization of Jup 1 0.24 2.84 0.03 86.16
8 INT159760 Localization of Pvrl1 1 0.13 0.14 0.09 85.84
9 INT161702 Gene_expression of GJB2 3 0.65 2.19 0.14 83.76
10 INT159756 Transcription of Slurp1 1 0.53 0.34 1.13 78.92
11 INT159761 Regulation of Slurp1 1 0.27 0.17 0.55 78.92
12 INT234864 Gene_expression of Dsp 30 0.47 17.72 0.37 76.56
13 INT234898 Negative_regulation of Gene_expression of Dsp 1 0.02 3.92 0.03 76.56
14 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 76.08
15 INT234952 Protein_catabolism of DSG1 3 0.96 5.86 0.98 64.64
16 INT213672 Positive_regulation of LRFN2 1 0.01 0.59 0.03 57.72
17 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 57.12
18 INT213671 Positive_regulation of COX4I1 1 0.00 0.58 0.03 56.60
19 INT175651 Gene_expression of CDH2 5 0.36 2.59 0 56.16
20 INT213669 Positive_regulation of COL4A3 2 0.00 1.24 0.23 56.12
21 INT140647 Gene_expression of DSG1 45 0.75 27.95 1.33 55.32
22 INT221864 Binding of JUP 2 0.36 1.05 0 48.88
23 INT228409 Localization of DSP 5 0.73 2.39 0.11 10.56
24 INT234856 Localization of Dsc2 1 0.21 1.28 0 10.56
25 INT234914 Localization of Pkp2 1 0.06 1.47 0 10.56
26 INT234937 Localization of DSG1 5 0.66 4.14 0 10.56
27 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
28 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 5.00
29 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 5.00
30 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
31 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
32 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
33 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 5.00
34 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 5.00
35 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
36 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 5.00
37 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 5.00
38 INT17561 Localization of Car2 303 0.79 60.95 44.52 5.00
39 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 5.00
40 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
41 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
42 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
43 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43 5.00
44 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 5.00
45 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 5.00
46 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
47 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
48 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68 5.00
49 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 5.00
50 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
51 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 5.00
52 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15 5.00
53 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 5.00
54 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 5.00
55 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
56 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32 5.00
57 INT25170 Positive_regulation of Localization of Car2 78 0.67 15.25 11.24 5.00
58 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64 5.00
59 INT1129 Binding of Car2 69 0.35 14.01 9.2 5.00
60 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
61 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 5.00
62 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 5.00
63 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74 5.00
64 INT29556 Negative_regulation of CALM1 26 0.57 9.08 6.04 5.00
65 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82 5.00
66 INT127276 Gene_expression of Slurp1 12 0.59 4.99 5.73 5.00
67 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61 5.00
68 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56 5.00
69 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54 5.00
70 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32 5.00
71 INT176524 Binding of Mapk14 19 0.43 12.54 5.21 5.00
72 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
73 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06 5.00
74 INT115927 Negative_regulation of Hspg2 27 0.57 4.16 4.53 5.00
75 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 5.00
76 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07 5.00
77 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 5.00
78 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75 5.00
79 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 5.00
80 INT1653 Positive_regulation of DSP 8 0.49 3.3 2.93 5.00
81 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61 5.00
82 INT165841 Gene_expression of BPIFA4P 17 0.65 6.48 2.38 5.00
83 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26 5.00
84 INT92316 Gene_expression of Plaur 30 0.61 22.06 2.21 5.00
85 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19 5.00
86 INT88464 Negative_regulation of CST7 11 0.31 5.33 2.17 5.00
87 INT70987 Binding of RAC1 14 0.37 12.14 2.13 5.00
88 INT152771 Gene_expression of TJP1 19 0.75 14.95 1.98 5.00
89 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88 5.00
90 INT112131 Positive_regulation of Positive_regulation of Egfr 10 0.49 9.95 1.85 5.00
91 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66 5.00
92 INT146566 Transcription of Car2 8 0.56 1.51 1.6 5.00
93 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4 5.00
94 INT41381 Positive_regulation of Gene_expression of Plg 8 0.44 3.29 1.3 5.00
95 INT234893 Positive_regulation of Adam17 4 0.38 3.78 1.22 5.00
96 INT9205 Binding of DSP 12 0.44 9.9 1.21 5.00
97 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19 5.00
98 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16 5.00
99 INT140052 Binding of Cish 12 0.39 1.63 1.1 5.00
100 INT71498 Binding of Hspb1 7 0.42 7.38 1.05 5.00
101 INT101889 Negative_regulation of DSP 3 0.42 1.61 1.05 5.00
102 INT95577 Gene_expression of Afm 2 0.20 1.76 0.97 5.00
103 INT178391 Localization of Mapk14 9 0.68 5.27 0.97 5.00
104 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96 5.00
105 INT80498 Gene_expression of DSP 15 0.75 7.06 0.79 5.00
106 INT131286 Binding of Egfr 26 0.44 13.58 0.78 5.00
107 INT234950 Binding of DSG1 29 0.36 23.67 0.69 5.00
108 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67 5.00
109 INT234928 Phosphorylation of Hspb1 3 0.72 17.04 0.65 5.00
110 INT234954 Negative_regulation of DSG1 22 0.42 19.5 0.62 5.00
111 INT200797 Positive_regulation of Ptprv 4 0.14 3.19 0.58 5.00
112 INT234872 Phosphorylation of Hspb2 4 0.24 3.12 0.49 5.00
113 INT234930 Binding of Dsg3 25 0.48 20.73 0.44 5.00
114 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42 5.00
115 INT51148 Gene_expression of CDH16 6 0.34 2.42 0.42 5.00
116 INT234876 Negative_regulation of Dsg3 29 0.59 25.47 0.4 5.00
117 INT90354 Negative_regulation of Myc 6 0.57 4.24 0.4 5.00
118 INT151662 Negative_regulation of Gsk3a 3 0.15 0.55 0.37 5.00
119 INT234962 Positive_regulation of Gene_expression of DSG1 5 0.48 5.41 0.37 5.00
120 INT226835 Gene_expression of Cdh2 14 0.22 8.04 0.31 5.00
121 INT234949 Phosphorylation of CTNND1 1 0.61 1.9 0.28 5.00
122 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26 5.00
123 INT234865 Binding of Dsp 1 0.02 2.48 0.25 5.00
124 INT106733 Regulation of CDK2 6 0.44 4.76 0.23 5.00
125 INT102071 Negative_regulation of Gene_expression of Myc 8 0.57 3.5 0.22 5.00
126 INT234858 Binding of Cdh1 11 0.47 4.58 0.22 5.00
127 INT234855 Localization of Dsp 1 0.03 1.65 0.22 5.00
128 INT186734 Protein_catabolism of IgG 3 0.26 2.36 0.21 5.00
129 INT234933 Gene_expression of Dsg2 3 0.71 38.52 0.2 5.00
130 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2 5.00
131 INT234908 Negative_regulation of Binding of Dsg3 1 0.31 7.18 0.19 5.00
132 INT234925 Positive_regulation of Phosphorylation of Hspb2 1 0.11 3.52 0.19 5.00
133 INT164682 Gene_expression of PKP1 3 0.78 3.04 0.17 5.00
134 INT234929 Negative_regulation of Negative_regulation of Dsg3 1 0.31 3.12 0.16 5.00
135 INT234895 Positive_regulation of Binding of Dsp 1 0.02 0.13 0.15 5.00
136 INT234857 Gene_expression of Dsg3 42 0.78 27.75 0.14 5.00
137 INT84750 Negative_regulation of Gene_expression of DSP 2 0.42 0.41 0.11 5.00
138 INT234888 Binding of Dsg2 9 0.34 11.73 0.11 5.00
139 INT234869 Negative_regulation of Binding of Dsg2 1 0.12 5.34 0.11 5.00
140 INT234958 Gene_expression of DSC3 1 0.10 2.75 0.11 5.00
141 INT234909 Phosphorylation of Dnajc27 1 0.01 1.47 0.11 5.00
142 INT234932 Negative_regulation of Phosphorylation of Hspb2 1 0.09 1.43 0.1 5.00
143 INT234907 Protein_catabolism of Dsg2 1 0.13 1.82 0.1 5.00
144 INT201460 Positive_regulation of Gene_expression of CDK2 5 0.52 2.8 0.09 5.00
145 INT234917 Negative_regulation of Gene_expression of Dsg3 1 0.31 3.16 0.09 5.00
146 INT231161 Gene_expression of Vcl 3 0.26 0.77 0.08 5.00
147 INT234922 Negative_regulation of Dsp 1 0.02 6.01 0.08 5.00
148 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08 5.00
149 INT234887 Positive_regulation of Binding of Dsg3 1 0.26 0.8 0.08 5.00
150 INT234926 Protein_catabolism of Gsk3b 2 0.58 1.33 0.08 5.00
151 INT234906 Positive_regulation of Protein_catabolism of Gsk3b 2 0.33 1.33 0.08 5.00
152 INT234955 Positive_regulation of Gene_expression of DSC3 1 0.06 0.1 0.07 5.00
153 INT178721 Positive_regulation of DSG1 2 0.34 0.1 0.06 5.00
154 INT234866 Regulation of Jup 2 0.08 0.58 0.06 5.00
155 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06 5.00
156 INT17893 Positive_regulation of Myc 4 0.67 3.28 0.06 5.00
157 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06 5.00
158 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06 5.00
159 INT234959 Negative_regulation of DSC3 1 0.05 0.14 0.05 5.00
160 INT192016 Localization of RYR2 5 0.25 4.18 0.05 5.00
161 INT232850 Phosphorylation of Krt8 7 0.52 3.8 0.05 5.00
162 INT221865 Positive_regulation of Localization of RYR2 2 0.15 4.56 0.05 5.00
163 INT234920 Negative_regulation of Positive_regulation of IgG 3 0.16 2.17 0.04 5.00
164 INT234905 Positive_regulation of Dsg3 1 0.26 0.73 0.04 5.00
165 INT234919 Negative_regulation of Dsg2 5 0.39 6.76 0.04 5.00
166 INT234884 Negative_regulation of Binding of Dsp 1 0.03 1.49 0.04 5.00
167 INT213670 Negative_regulation of GJB1 1 0.58 0.65 0.04 5.00
168 INT234961 Binding of NKS1 1 0.01 0.5 0.04 5.00
169 INT201426 Phosphorylation of IgG 2 0.10 0.56 0.04 5.00
170 INT234951 Negative_regulation of Binding of DSG1 1 0.29 11.2 0.03 5.00
171 INT234890 Phosphorylation of Jup 1 0.24 1.56 0.03 5.00
172 INT234880 Regulation of Gene_expression of Dsp 1 0.02 4.75 0.03 5.00
173 INT234944 Positive_regulation of Binding of DSG1 1 0.23 0.84 0 5.00
174 INT234860 Protein_catabolism of Dsg3 1 0.52 0.85 0 5.00
175 INT234936 Regulation of CCND2 1 0.04 1.15 0 5.00
176 INT234927 Positive_regulation of Protein_catabolism of Dsg3 1 0.36 0.25 0 5.00
177 INT234859 Negative_regulation of Positive_regulation of Dsp 1 0.02 0.85 0 5.00
178 INT234886 Regulation of Dsg2 1 0.09 0.67 0 5.00
179 INT234912 Protein_catabolism of Dsp 1 0.05 2.04 0 5.00
180 INT234885 Localization of Dsg3 1 0.39 0.33 0 5.00
181 INT175216 Negative_regulation of Binding of GOPC 5 0.10 2.05 0 5.00
182 INT234923 Binding of Dsc2 2 0.34 1.8 0 5.00
183 INT234956 Localization of PKP1 1 0.14 0.2 0 5.00
184 INT213673 Negative_regulation of ATP6V1A 1 0.02 0.49 0 5.00
185 INT234901 Positive_regulation of Gene_expression of Dsg3 1 0.36 1.94 0 5.00
186 INT234877 Positive_regulation of Binding of Jup 1 0.21 0.24 0 5.00
187 INT234916 Gene_expression of Lef1 1 0.04 0.25 0 5.00
188 INT199086 Binding of Sergef 2 0.08 0.28 0 5.00
189 INT89582 Binding of PKP1 3 0.36 0.85 0 5.00
190 INT234939 Positive_regulation of Negative_regulation of DSG1 1 0.23 0.74 0 5.00
191 INT234945 Negative_regulation of PKP3 1 0.04 1.22 0 5.00
192 INT234938 Regulation of Negative_regulation of DSG1 1 0.22 1.21 0 5.00
193 INT234941 Gene_expression of DSC1 1 0.28 0.67 0 5.00
194 INT234942 Negative_regulation of CDH16 1 0.01 1.14 0 5.00
195 INT234879 Binding of Pitx3 2 0.11 1.21 0 5.00
196 INT234948 Negative_regulation of DSC1 1 0.07 0.07 0 5.00
197 INT234868 Regulation of Dsp 1 0.02 0.83 0 5.00
198 INT234957 Positive_regulation of Phosphorylation of DSG1 1 0.34 0.53 0 5.00
199 INT234873 Regulation of Dsc2 1 0.08 1.2 0 5.00
200 INT234940 Regulation of DSG1 2 0.21 2.29 0 5.00
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