D:Volume Depletion And Dehydration

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Disease Term
Synonyms DEHYDRATION, Depletion Of Volume Of Extracellular Fluid, Depletion Of Volume Of Plasma, Fluid Depletion, FLUID VOLUME DEPLETION, Hypovolaemia, Hypovolemia, Sodium Water Depletion, Volume Dehydration, Volume Depletion
Documents 1523
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Volume Depletion And Dehydration. They are ordered first by their relevance to Volume Depletion And Dehydration and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09 99.84
2 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15 99.20
3 INT227556 Ptgds Positive_regulation of Ppara 1 0.18 0.62 0.13 98.38
4 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36 96.36
5 INT290861 MNT Positive_regulation of INS 1 0.03 1.78 0 94.72
6 INT126766 Binding of PTGDS and PTGDR2 4 0.40 1.62 0.93 94.28
7 INT264522 Binding of GPER and PTGDS 1 0.03 1.22 0.4 94.28
8 INT264525 Binding of PTGDS and PTGFR 1 0.02 1.22 0.39 94.28
9 INT75126 Pnoc Regulation of Localization of Avp 2 0.26 0.24 1.18 91.84
10 INT250913 Col7a1 Regulation of Thbs2 Regulation of Col7a1 1 0.00 0.35 0.13 83.28
11 INT250912 Thbs2 Regulation of Thbs2 Regulation of Col7a1 1 0.03 0.35 0.13 83.28
12 INT250907 Thbs2 Regulation of Col7a1 1 0.03 0.35 0.13 83.28
13 INT111151 Tip39 Regulation of Localization of Avp 1 0.27 0.15 0.12 82.08
14 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17 80.32
15 INT177714 Binding of GALNT3 and REN 1 0.01 2.36 0.12 79.20
16 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63 78.64
17 INT246710 Salc1 Regulation of Cebpz 1 0.04 1.67 0 78.28
18 INT246709 Ins1 Regulation of Cebpz 1 0.05 1.67 0 78.28
19 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45 75.00
20 INT111152 Pthlh Positive_regulation of Localization of Avp 1 0.53 0.26 0.18 73.44
21 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13 72.64
22 INT250910 Thbs2 Regulation of Tgm2 1 0.04 0.3 0.13 72.64
23 INT280826 Il6 Positive_regulation of Localization of Avp 1 0.01 0.64 0.47 70.88
24 INT322207 CCL18 Regulation of Gene_expression of COL7A1 1 0.07 0.88 0.09 67.28
25 INT265344 sb Negative_regulation of Tgfbr1 1 0.00 0.06 0 63.12
26 INT319786 Ccbp2 Positive_regulation of Negative_regulation of Dio1 1 0.09 0.94 0.05 61.32
27 INT196606 IFNG Positive_regulation of CFTR 1 0.16 0.45 0.16 60.88
28 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 56.88
29 INT232174 GAN Positive_regulation of ODT 1 0.01 0.98 0.14 54.76
30 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19 53.76
31 INT184209 IL1B Negative_regulation of Gene_expression of SOX6 1 0.46 0.05 0.03 53.08
32 INT263248 Binding of ADD1 and RAPGEF5 1 0.01 0.84 0 52.80
33 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03 48.40
34 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35 46.24
35 INT196614 TNF Positive_regulation of Positive_regulation of NA 1 0.03 0.88 0.24 39.32
36 INT196615 TNF Positive_regulation of Negative_regulation of DNAH8 1 0.02 0.88 0.24 39.32
37 INT196620 TNF Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.88 0.24 39.32
38 INT196609 IFNG Positive_regulation of Positive_regulation of NA 1 0.03 0.87 0.24 38.84
39 INT196622 IFNG Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.87 0.24 38.84
40 INT196646 IFNG Positive_regulation of Negative_regulation of DNAH8 1 0.03 0.87 0.24 38.84
41 INT280839 Il6 Positive_regulation of Gene_expression of Crh 1 0.09 0.1 0.19 35.68
42 INT162241 Binding of COL7A1 and MMP13 2 0.03 0.86 0.73 34.16
43 INT28863 Mtr Negative_regulation of Dhfr 1 0.04 0.87 0.45 31.60
44 INT28864 Mtx1 Negative_regulation of Dhfr 1 0.19 0.87 0.44 31.60
45 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47 31.12
46 INT184210 IL1B Negative_regulation of Gene_expression of COL1A2 1 0.04 0 0 27.16
47 INT263249 Binding of ADD1 and REN 1 0.03 0.82 0 24.24
48 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08 23.36
49 INT254640 CGA Positive_regulation of REN 1 0.07 1.51 0.08 23.36
50 INT254639 CGA Positive_regulation of Gene_expression of AGT 1 0.18 1.51 0.08 23.36
51 INT319787 Binding of Dio1 and Ccbp2 1 0.06 0.92 0.03 22.32
52 INT280833 Il1 Positive_regulation of Gene_expression of Crh 1 0.05 0.09 0.17 21.20
53 INT196647 IFNG Negative_regulation of NA 1 0.04 0.79 0.24 18.28
54 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3 14.64
55 INT322206 CCL18 Positive_regulation of Gene_expression of COL7A1 1 0.05 0.28 0.05 14.12
56 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
57 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
58 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
59 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49 5.00
60 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
61 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64 5.00
62 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
63 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5 5.00
64 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 5.00
65 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37 5.00
66 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 5.00
67 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06 5.00
68 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 5.00
69 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98 5.00
70 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
71 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91 5.00
72 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 5.00
73 INT204552 Sult2a2 Regulation of Cia1 1 0.01 2.75 1.75 5.00
74 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
75 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26 5.00
76 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 5.00
77 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11 5.00
78 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07 5.00
79 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06 5.00
80 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04 5.00
81 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
82 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03 5.00
83 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98 5.00
84 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94 5.00
85 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93 5.00
86 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93 5.00
87 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87 5.00
88 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85 5.00
89 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84 5.00
90 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84 5.00
91 INT186567 Negative_regulation of Hpcl1 Positive_regulation of Fos 1 0.11 0.07 0.82 5.00
92 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82 5.00
93 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8 5.00
94 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79 5.00
95 INT351322 Nts Regulation of Localization of Napa 1 0.01 0.56 0.77 5.00
96 INT73776 Regulation of Binding of GH1 and GHR 2 0.26 0.16 0.75 5.00
97 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
98 INT307754 Ik Negative_regulation of Trpa1 1 0.07 0.08 0.71 5.00
99 INT190527 TNF Positive_regulation of Gene_expression of Ros1 1 0.01 1.02 0.68 5.00
100 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68 5.00
101 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67 5.00
102 INT171825 Binding of Prkcg and Ncs1 1 0.00 0.07 0.66 5.00
103 INT171824 Binding of Ncs1 and Aspm 1 0.00 0.07 0.65 5.00
104 INT186569 Regulation of Hpcl1 Positive_regulation of Fos 1 0.07 0 0.65 5.00
105 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64 5.00
106 INT190525 Acot1 Positive_regulation of Localization of S100a8 1 0.00 0.86 0.63 5.00
107 INT190526 Acot1 Positive_regulation of Il1 1 0.01 0.87 0.63 5.00
108 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
109 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
110 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57 5.00
111 INT284461 Gtf3a Positive_regulation of Gene_expression of IFN1@ 1 0.01 0.56 0.57 5.00
112 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 5.00
113 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52 5.00
114 INT327090 Negative_regulation of F12 Negative_regulation of Gene_expression of KNG1 1 0.00 0.51 0.45 5.00
115 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44 5.00
116 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43 5.00
117 INT325701 Aacs Regulation of Car3 1 0.17 0 0.4 5.00
118 INT204793 T Positive_regulation of Mthfd1 1 0.00 1.32 0.39 5.00
119 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38 5.00
120 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38 5.00
121 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38 5.00
122 INT264527 IL1B Positive_regulation of Gene_expression of PTGDS 1 0.07 0.75 0.38 5.00
123 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38 5.00
124 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36 5.00
125 INT171823 Nrgn Positive_regulation of Prkcg 1 0.18 0.53 0.36 5.00
126 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36 5.00
127 INT340607 Bdnf Regulation of Gene_expression of Creb1 1 0.36 0.31 0.36 5.00
128 INT279369 Binding of ADA and Ifx 1 0.29 0.27 0.35 5.00
129 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 5.00
130 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 5.00
131 INT196644 PTGER2 Positive_regulation of Gene_expression of NA 1 0.00 0.93 0.35 5.00
132 INT322208 HRCT1 Positive_regulation of PDX1 1 0.01 1.31 0.34 5.00
133 INT102341 Binding of Slc6a3 and Flvcr2 2 0.06 0 0.34 5.00
134 INT264521 PTGDS Negative_regulation of Positive_regulation of MMP1 1 0.06 1.42 0.34 5.00
135 INT280808 Prkcg Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
136 INT353128 Negative_regulation of Binding of TAC1 and B3GAT1 1 0.29 1.95 0.33 5.00
137 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 5.00
138 INT280838 Binding of Crh and gr 1 0.06 0 0.33 5.00
139 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
140 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 5.00
141 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32 5.00
142 INT196618 Binding of KNG1 and Positive_regulation of NA 1 0.01 0.19 0.32 5.00
143 INT204792 Tnbs1 Positive_regulation of Transcription of Il10 1 0.09 1.2 0.32 5.00
144 INT196623 Binding of KNG1 and Positive_regulation of DNAH8 1 0.01 0.19 0.32 5.00
145 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32 5.00
146 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31 5.00
147 INT212643 Pvalb Negative_regulation of Cfp 1 0.08 0 0.31 5.00
148 INT196605 Binding of DNAH8 and SPANXB1 Positive_regulation of DNAH8 1 0.00 0.08 0.3 5.00
149 INT254287 Binding of TNFSF13B and TNFRSF13B 1 0.01 1.33 0.3 5.00
150 INT196604 Binding of DNAH8 and SPANXB1 Positive_regulation of NA 1 0.00 0.08 0.3 5.00
151 INT254288 Binding of ZNF623 and TNFSF13B 1 0.00 1.33 0.3 5.00
152 INT264523 PTGDS Positive_regulation of Gene_expression of COL2A1 1 0.03 1.24 0.3 5.00
153 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
154 INT196641 Binding of KNG1 and Negative_regulation of DNAH8 1 0.01 0.19 0.29 5.00
155 INT285327 Binding of Cox8b and Gtf2ird2 1 0.00 0.9 0.29 5.00
156 INT196612 Binding of KNG1 and Negative_regulation of NA 1 0.01 0.19 0.29 5.00
157 INT196621 PTGER2 Negative_regulation of Gene_expression of DNAH8 1 0.00 0.33 0.28 5.00
158 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28 5.00
159 INT280827 Positive_regulation of Fos Positive_regulation of Avp 1 0.02 0.08 0.28 5.00
160 INT196631 PTGER2 Negative_regulation of NFKB1 1 0.00 0.32 0.28 5.00
161 INT280825 Mapk1 Positive_regulation of Avp 1 0.01 0.08 0.28 5.00
162 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28 5.00
163 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28 5.00
164 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 5.00
165 INT196626 Binding of DNAH8 and KNG1 1 0.00 0.08 0.27 5.00
166 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27 5.00
167 INT196637 Binding of DNAH8 and SPANXB1 1 0.00 0.08 0.27 5.00
168 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27 5.00
169 INT196613 Binding of KNG1 and NA 1 0.01 0.08 0.27 5.00
170 INT280850 Binding of Crh and Ucn Positive_regulation of Negative_regulation of Crh 1 0.26 0.06 0.27 5.00
171 INT280822 Jun Regulation of Regulation of Crh 1 0.20 0.08 0.27 5.00
172 INT196616 Binding of NA and SPANXB1 1 0.00 0.08 0.27 5.00
173 INT280805 Positive_regulation of Prkcg Positive_regulation of Avp 1 0.01 0.16 0.26 5.00
174 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26 5.00
175 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26 5.00
176 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26 5.00
177 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26 5.00
178 INT201075 Binding of TNF and Cxcr1 1 0.00 0.31 0.26 5.00
179 INT220681 Binding of F10 and tf 1 0.03 1.47 0.26 5.00
180 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26 5.00
181 INT351007 Binding of IL2 and IL2RA 1 0.33 1.33 0.26 5.00
182 INT280811 Binding of Crhr1 and Ucn3 1 0.08 0.05 0.25 5.00
183 INT245590 Ghr Positive_regulation of Gene_expression of Igf1 1 0.34 0.61 0.23 5.00
184 INT264524 PTGDS Negative_regulation of Gene_expression of MMP1 1 0.09 0.5 0.22 5.00
185 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22 5.00
186 INT264526 PTGDS Negative_regulation of Gene_expression of MMP13 1 0.12 0.5 0.22 5.00
187 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22 5.00
188 INT121050 Crh Regulation of Localization of Pomc 4 0.43 0.6 0.22 5.00
189 INT264517 PTGDS Positive_regulation of TFDP1 1 0.17 0.5 0.22 5.00
190 INT264516 PTGDS Positive_regulation of TFDP1 Negative_regulation of Gene_expression of MMP1 1 0.02 0.5 0.22 5.00
191 INT196629 PTGER2 Negative_regulation of Gene_expression of NA 1 0.00 0.24 0.22 5.00
192 INT264519 PTGDS Negative_regulation of Positive_regulation of TFDP1 1 0.15 0.5 0.22 5.00
193 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21 5.00
194 INT277434 Cd5 Regulation of Gdnf 1 0.01 0 0.21 5.00
195 INT220676 tf Positive_regulation of Gene_expression of Ik 1 0.00 0.66 0.21 5.00
196 INT197811 Binding of SMS and SST 1 0.00 0.98 0.21 5.00
197 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2 5.00
198 INT220678 Positive_regulation of Binding of tf and Par2 1 0.16 0.71 0.2 5.00
199 INT220683 Binding of tf and PAR1 1 0.06 0.7 0.2 5.00
200 INT201440 Negative_regulation of Ngf Positive_regulation of Slc6a3 1 0.10 0 0.2 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Volume Depletion And Dehydration. They are ordered first by their pain relevance and then by number of times they were reported in Volume Depletion And Dehydration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9164 Regulation of MSLN 23 0.26 3.58 0.34 100.00
2 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 100.00
3 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7 100.00
4 INT189449 Regulation of Gene_expression of MSLN 1 0.19 0.34 0 100.00
5 INT1612 Regulation of Binding of Oprl1 19 0.62 2.34 12.45 100.00
6 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 100.00
7 INT1334 Negative_regulation of Binding of Oprl1 29 0.59 3.03 20.62 99.98
8 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7 99.98
9 INT214 Localization of AVP 370 0.81 208.51 91.09 99.96
10 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 99.96
11 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 99.96
12 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 99.92
13 INT85621 Regulation of PRNP 16 0.60 8.7 1.15 99.92
14 INT1261 Localization of Adh1 63 0.81 19.36 16.09 99.84
15 INT4261 Positive_regulation of Localization of Adh1 11 0.61 2.04 3.49 99.84
16 INT24283 Regulation of Positive_regulation of CA2 8 0.30 3.06 1.74 99.84
17 INT8392 Regulation of Gene_expression of Qrfp 37 0.54 6.9 19.02 99.82
18 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 99.80
19 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11 99.78
20 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 99.76
21 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57 99.76
22 INT292782 Positive_regulation of Positive_regulation of SHOX 1 0.02 0.42 0 99.76
23 INT65069 Positive_regulation of SHOX 3 0.02 0.92 1.21 99.76
24 INT654 Localization of REN 250 0.81 75.12 47.86 99.74
25 INT58550 Gene_expression of SON 8 0.43 0.99 0.88 99.74
26 INT451 Regulation of Oxt 142 0.62 22.07 69.42 99.72
27 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 99.70
28 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.70
29 INT477 Localization of Avp 813 0.81 131.58 300.4 99.68
30 INT3579 Localization of Oxt 555 0.81 43.35 292.44 99.68
31 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 99.68
32 INT4207 Regulation of Avp 267 0.62 63.72 115.33 99.68
33 INT21609 Positive_regulation of RASGRP1 58 0.50 40.78 5.47 99.68
34 INT8346 Gene_expression of Qrfp 136 0.70 19.49 70.21 99.60
35 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 99.60
36 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 99.56
37 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47 99.56
38 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 99.56
39 INT10627 Positive_regulation of Lnpep 24 0.69 3.36 7.85 99.56
40 INT12903 Gene_expression of Lnpep 14 0.71 1.3 2.78 99.56
41 INT30783 Positive_regulation of Gene_expression of Lnpep 3 0.64 0.66 0.53 99.56
42 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 99.52
43 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 99.52
44 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 99.48
45 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4 99.48
46 INT2367 Binding of Sct 34 0.42 8.46 8.62 99.44
47 INT66002 Binding of LAMC2 9 0.47 4.5 2.54 99.44
48 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 99.40
49 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82 99.36
50 INT4438 Negative_regulation of Localization of Adh1 18 0.59 6.23 6.95 99.36
51 INT3826 Positive_regulation of Tfpi 10 0.61 2.26 4.16 99.26
52 INT37734 Positive_regulation of Ang 18 0.46 9.17 2.87 99.26
53 INT68952 Localization of PCNA 17 0.62 5.64 1.78 99.24
54 INT189446 Gene_expression of MSLN 24 0.42 13.37 0.47 99.22
55 INT94393 Localization of ANGPT2 8 0.17 5.02 0.96 99.20
56 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 99.14
57 INT56792 Positive_regulation of Negative_regulation of F13A1 2 0.12 1.51 0.42 99.14
58 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 99.12
59 INT275878 Positive_regulation of Gene_expression of Aes 4 0.23 4.54 3.39 99.12
60 INT355463 Gene_expression of SPRED1 1 0.56 6.96 0.24 99.10
61 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71 99.06
62 INT187017 Positive_regulation of Bcar1 2 0.44 2.02 0.27 99.06
63 INT179644 Gene_expression of RENBP 26 0.35 13.74 1.38 99.04
64 INT248313 Positive_regulation of Slc22a12 1 0.02 1.55 0.04 99.02
65 INT16286 Positive_regulation of GHR 8 0.60 4.04 2.31 99.00
66 INT4598 Negative_regulation of Adh1 15 0.54 4.69 5.33 98.96
67 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 98.96
68 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 98.94
69 INT150422 Positive_regulation of Aes 24 0.43 15.63 8 98.92
70 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79 98.88
71 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 98.88
72 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99 98.80
73 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 98.80
74 INT267269 Gene_expression of BCL11B 62 0.78 48.75 0.55 98.76
75 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 98.72
76 INT103463 Localization of CPP 16 0.66 9.63 4.08 98.72
77 INT182516 Negative_regulation of Negative_regulation of ACE 9 0.42 6.84 0.99 98.64
78 INT251502 Gene_expression of AVPR1A 2 0.65 1.72 0.33 98.64
79 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 98.52
80 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 98.48
81 INT2157 Positive_regulation of Gene_expression of LH 24 0.69 6.07 8.67 98.48
82 INT258183 Negative_regulation of GCSH 1 0.02 2.33 0.05 98.48
83 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 98.46
84 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 98.44
85 INT1158 Regulation of Agt 106 0.61 29.4 30.29 98.40
86 INT4047 Binding of F13A1 105 0.43 66.54 11.81 98.36
87 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5 98.20
88 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94 98.20
89 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61 98.20
90 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 98.20
91 INT248314 Negative_regulation of Slc22a12 1 0.01 1.47 0.04 98.18
92 INT1046 Gene_expression of LH 180 0.77 29.75 66.87 98.16
93 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 98.12
94 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09 98.12
95 INT262348 Gene_expression of Lgsn 12 0.58 12.64 2.08 98.08
96 INT16431 Localization of Lnpep 62 0.70 6.28 23.94 98.08
97 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72 98.00
98 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 97.96
99 INT71764 Positive_regulation of Mri1 24 0.44 12.31 5.67 97.96
100 INT1438 Localization of Pomc 360 0.81 101.26 116.47 97.90
101 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 97.88
102 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59 97.88
103 INT276620 Negative_regulation of Cdh1 7 0.57 6.48 0.86 97.84
104 INT2442 Localization of Mb 38 0.80 24.74 6.33 97.76
105 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 97.68
106 INT80108 Regulation of SON 1 0.02 0.59 0.38 97.68
107 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 97.60
108 INT5988 Localization of Dbi 74 0.81 17.52 24.09 97.56
109 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 97.46
110 INT121796 Gene_expression of NeuN 92 0.78 23.18 10.53 97.36
111 INT246708 Regulation of Gene_expression of Cebpz 1 0.39 2.2 0.08 97.36
112 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 97.28
113 INT1168 Binding of PROC 62 0.38 44.15 9.04 97.10
114 INT109209 Negative_regulation of Gene_expression of Slc5a3 1 0.23 0.34 0.63 97.08
115 INT109210 Negative_regulation of Gene_expression of Miox 2 0.08 0.34 0.63 97.08
116 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 96.92
117 INT265987 Protein_catabolism of ALAS2 1 0.01 2.77 0.07 96.92
118 INT150146 Positive_regulation of Kcnn3 6 0.66 0.92 0.46 96.88
119 INT292781 Positive_regulation of Positive_regulation of Kcnn3 1 0.01 0.49 0 96.88
120 INT5039 Positive_regulation of Gal 67 0.68 27.97 37.36 96.84
121 INT4651 Gene_expression of Cebpz 39 0.00 20.19 8.5 96.80
122 INT9779 Gene_expression of Glb1 23 0.58 8.01 6.04 96.60
123 INT109211 Gene_expression of Slc5a3 3 0.41 0.66 1.3 96.60
124 INT109208 Gene_expression of Miox 3 0.15 1.19 1.16 96.60
125 INT34425 Positive_regulation of Negative_regulation of NA 12 0.38 4.17 3.2 96.56
126 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21 96.52
127 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 96.50
128 INT121531 Negative_regulation of DNMT3B 13 0.36 3.46 3.05 96.44
129 INT68522 Localization of Pcsk1n 2 0.56 1.19 1.85 96.40
130 INT287 Localization of Cck 518 0.81 86.84 364.04 96.36
131 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42 96.32
132 INT15262 Negative_regulation of Positive_regulation of Avp 22 0.58 3.28 10.81 96.28
133 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79 96.28
134 INT306073 Binding of ADH5 1 0.06 0.88 0 96.20
135 INT202716 Gene_expression of NMS 4 0.49 4.56 0.57 96.20
136 INT5617 Localization of Nppa 266 0.81 83.51 83.89 96.08
137 INT238313 Gene_expression of Hspg2 9 0.58 3.42 3.15 96.00
138 INT100482 Localization of Cebpz 6 0.65 4.82 1.2 96.00
139 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16 95.96
140 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 95.92
141 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 95.88
142 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65 95.80
143 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 95.76
144 INT4830 Binding of Trpv1 158 0.48 45.11 84.2 95.72
145 INT5454 Localization of CRH 124 0.79 79.18 41.53 95.72
146 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 95.64
147 INT27656 Gene_expression of Tgfa 6 0.74 3.37 1.32 95.56
148 INT292780 Positive_regulation of Etl4 1 0.01 0.55 0 95.40
149 INT20981 Binding of HRAS 42 0.48 24.49 4.23 95.36
150 INT218760 Negative_regulation of ZEB1 4 0.38 1.38 0.09 95.36
151 INT289306 Positive_regulation of Serpinb1b 6 0.41 2.83 0.48 95.28
152 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01 95.24
153 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 95.24
154 INT30943 Negative_regulation of Pthlh 3 0.20 2.75 0.56 95.16
155 INT121336 Positive_regulation of HTT 10 0.45 10.88 0.59 95.16
156 INT335 Binding of Adra1a 16 0.36 6.16 6 95.04
157 INT102615 Positive_regulation of Gene_expression of Tgfa 5 0.44 3.93 1.17 95.00
158 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 94.96
159 INT84527 Positive_regulation of Gene_expression of F3 16 0.49 15.83 2.85 94.96
160 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47 94.92
161 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 94.84
162 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 94.84
163 INT55309 Positive_regulation of Ssr1 20 0.46 5.97 5.74 94.84
164 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 94.76
165 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86 94.76
166 INT22276 Gene_expression of TBXA2R 65 0.77 23.22 14.21 94.72
167 INT29835 Regulation of Gene_expression of TBXA2R 7 0.50 3.92 2.57 94.72
168 INT3948 Regulation of Cck 291 0.62 58.07 255.88 94.64
169 INT184223 Positive_regulation of Gene_expression of ADAMTS4 6 0.43 1.07 0.98 94.44
170 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69 94.40
171 INT131977 Positive_regulation of Localization of Avp 6 0.55 4.9 1.31 94.40
172 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97 94.40
173 INT58166 Regulation of Gene_expression of Avp 13 0.57 2.63 2.76 94.40
174 INT200385 Negative_regulation of ADC 19 0.18 16.56 3.6 94.32
175 INT7491 Localization of Pdyn 80 0.81 3.94 58.77 94.32
176 INT25119 Binding of PTGDS 9 0.35 3.86 2.54 94.28
177 INT22003 Negative_regulation of Cpe 25 0.58 6.23 12.94 94.24
178 INT39226 Positive_regulation of Negative_regulation of Cpe 2 0.45 0.17 0.93 94.24
179 INT197842 Gene_expression of PHPT1 1 0.06 5.89 0.16 94.24
180 INT89159 Negative_regulation of Del(7)Tyr<c-23DVT>-p 5 0.34 6.8 0.68 94.08
181 INT173591 Gene_expression of ADAMTS4 7 0.48 3.65 4.8 93.96
182 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 93.84
183 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 93.80
184 INT230 Positive_regulation of GGTLC1 14 0.68 11.78 1.55 93.80
185 INT36337 Localization of Tgfa 4 0.73 0.83 1.32 93.68
186 INT18838 Positive_regulation of Regulation of Avp 3 0.47 0.48 3.32 93.64
187 INT138844 Positive_regulation of CC2D1A 25 0.41 41.36 1.92 93.52
188 INT1044 Negative_regulation of Localization of LH 358 0.59 25.95 151.31 93.52
189 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 93.52
190 INT18830 Localization of TBXA2R 25 0.81 7.14 9.28 93.40
191 INT40962 Localization of Avp 40 0.80 20.5 6.38 93.32
192 INT65855 Localization of TP53 18 0.76 17.08 1.89 93.20
193 INT127655 Localization of MKI67 6 0.73 3.72 0.26 93.20
194 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 93.16
195 INT629 Negative_regulation of Localization of PGC 8 0.45 5.79 1.33 93.16
196 INT625 Localization of PGC 35 0.80 11.33 3.05 93.16
197 INT17848 Binding of PTGS2 70 0.46 32.1 20.6 93.12
198 INT1045 Localization of LH 1211 0.81 87.04 456.25 93.04
199 INT653 Negative_regulation of Localization of REN 67 0.59 20.33 16.7 92.92
200 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 92.88
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