D:Vulvar Cancer

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pChart

Disease Term
Synonyms Cancer Of The Vulva, Cancer Of Vulva, CANCER VULVA, CANCER VULVAR, Cancers Vulva, Cancers Vulvar, Neoplasm Vulva, Neoplasm Vulvar, Neoplasms Vulva, Neoplasms Vulvar, VULVA CANCER
Documents 64
Hot Single Events 16
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Vulvar Cancer. They are ordered first by their relevance to Vulvar Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT235649 TP73 Regulation of EFNA1 1 0.09 0.97 0 87.20
2 INT235651 TP73 Regulation of EPHA2 1 0.15 0.98 0 87.20
3 INT235647 TP63 Regulation of EPHA2 1 0.15 0.97 0 86.56
4 INT235646 TP63 Regulation of EFNA1 1 0.09 0.97 0 86.56
5 INT235645 TP53 Regulation of EPHA2 1 0.10 0.97 0 86.16
6 INT235650 TP53 Regulation of EFNA1 1 0.06 0.97 0 86.16
7 INT235648 Binding of EFNA1 and EPHA2 1 0.23 1.3 0 77.40
8 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
9 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
10 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0 5.00
11 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0 5.00
12 INT263899 Binding of PTPRC and TMED7-TICAM2 1 0.00 0.85 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Vulvar Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Vulvar Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT235660 Gene_expression of EPHA2 27 0.75 23.46 0.4 99.44
2 INT235655 Positive_regulation of Gene_expression of EPHA2 14 0.67 13.48 0.35 99.44
3 INT235659 Gene_expression of EFNA1 1 0.45 22.92 0.06 99.08
4 INT235656 Positive_regulation of Gene_expression of EFNA1 1 0.40 8.86 0 99.08
5 INT235654 Binding of EPHA2 5 0.36 4.26 0 92.32
6 INT118286 Binding of EFNA1 3 0.21 4.95 1.55 92.32
7 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68 86.76
8 INT235658 Positive_regulation of EPHA2 4 0.67 3.42 0.32 86.76
9 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 85.12
10 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 85.12
11 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 84.00
12 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 84.00
13 INT70654 Gene_expression of Actg2 27 0.67 18.62 4.79 83.52
14 INT70760 Positive_regulation of Actg2 8 0.48 6.23 0.61 83.52
15 INT143850 Gene_expression of S100a1 19 0.73 9.52 1.54 80.72
16 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 80.48
17 INT235657 Localization of EFNA1 1 0.43 0.9 0 74.32
18 INT235652 Localization of EPHA2 1 0.72 0.89 0 73.20
19 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 70.64
20 INT235653 Binding of EPHB2 1 0.08 1.04 0 65.84
21 INT341719 Transcription of FAM49B 1 0.04 1.1 0 60.04
22 INT341718 Positive_regulation of Transcription of FAM49B 1 0.03 1.1 0 60.04
23 INT263905 Gene_expression of SLN 33 0.63 23.21 0.74 58.24
24 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 5.00
25 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
26 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47 5.00
27 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
28 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
29 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 5.00
30 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
31 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
32 INT2491 Regulation of Cea 38 0.61 26.18 10.95 5.00
33 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 5.00
34 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 5.00
35 INT182440 Gene_expression of CCNE2 39 0.53 22.07 7.44 5.00
36 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 5.00
37 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 5.00
38 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
39 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 5.00
40 INT17182 Binding of Cea 25 0.48 14.98 4.16 5.00
41 INT5286 Gene_expression of ANTXR2 46 0.75 21.06 3.41 5.00
42 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28 5.00
43 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 5.00
44 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 5.00
45 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31 5.00
46 INT73476 Transcription of MYC 18 0.69 12.14 2.13 5.00
47 INT65855 Localization of TP53 18 0.76 17.08 1.89 5.00
48 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
49 INT104524 Localization of FSCN1 3 0.13 1.76 1.75 5.00
50 INT73475 Positive_regulation of Transcription of MYC 7 0.67 5.46 1.66 5.00
51 INT68094 Negative_regulation of SERPINB3 12 0.43 10.55 1.49 5.00
52 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42 5.00
53 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41 5.00
54 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26 5.00
55 INT237247 Regulation of Mri1 6 0.27 4.64 1.2 5.00
56 INT146546 Gene_expression of MSI1 22 0.48 22.91 1.15 5.00
57 INT166261 Localization of SLN 2 0.66 1.23 1.07 5.00
58 INT86834 Positive_regulation of Tg 10 0.69 4.9 1.04 5.00
59 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
60 INT263912 Positive_regulation of SLN 6 0.39 0.66 0.99 5.00
61 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 5.00
62 INT61910 Binding of Slc3a2 6 0.01 3 0.7 5.00
63 INT246036 Positive_regulation of GRN 3 0.17 2.04 0.69 5.00
64 INT214707 Gene_expression of Slc2a8 5 0.24 2.76 0.61 5.00
65 INT88870 Negative_regulation of PDXP 4 0.43 4.64 0.57 5.00
66 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 5.00
67 INT263904 Negative_regulation of Gene_expression of SLN 1 0.14 7.18 0.47 5.00
68 INT68285 Gene_expression of SERPINB3 24 0.75 25.4 0.45 5.00
69 INT68288 Positive_regulation of SERPINB3 14 0.51 16.87 0.41 5.00
70 INT172626 Localization of E2F1 3 0.78 1.97 0.4 5.00
71 INT189755 Gene_expression of CCND3 42 0.65 10.88 0.39 5.00
72 INT158766 Localization of GRN 2 0.73 1.59 0.28 5.00
73 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25 5.00
74 INT286429 Positive_regulation of Gene_expression of ANTXR2 2 0.25 1.46 0.23 5.00
75 INT235663 Gene_expression of CCNA1 4 0.75 5.61 0.22 5.00
76 INT263884 Gene_expression of Slc2a3 2 0.18 0.86 0.19 5.00
77 INT20214 Localization of Slc3a2 5 0.14 4.91 0.16 5.00
78 INT236916 Gene_expression of Ccnd2 5 0.46 2.48 0.14 5.00
79 INT197627 Localization of RB1 3 0.69 4.16 0.13 5.00
80 INT263871 Negative_regulation of Car9 1 0.07 0.54 0.12 5.00
81 INT263908 Positive_regulation of Gene_expression of SLN 1 0.16 1.4 0.12 5.00
82 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12 5.00
83 INT263872 Localization of Adra1d 1 0.01 2.5 0.11 5.00
84 INT164637 Binding of MIB1 3 0.32 4.29 0.11 5.00
85 INT263878 Positive_regulation of Rigs1 1 0.05 2.57 0.07 5.00
86 INT214703 Positive_regulation of Gene_expression of Slc2a8 2 0.09 1.4 0.05 5.00
87 INT263879 Positive_regulation of Adra1d 1 0.00 0.47 0.04 5.00
88 INT263873 Positive_regulation of Gene_expression of Rigs1 1 0.05 1.27 0.03 5.00
89 INT263877 Gene_expression of Rigs1 1 0.08 11.58 0.03 5.00
90 INT263911 Localization of TMED7-TICAM2 1 0.01 1.02 0 5.00
91 INT350742 Positive_regulation of Positive_regulation of SERPINB3 1 0.04 2.54 0 5.00
92 INT263906 Gene_expression of TMED7-TICAM2 1 0.01 2.8 0 5.00
93 INT263874 Regulation of Rigs1 1 0.03 1.36 0 5.00
94 INT348463 Protein_catabolism of RB1 2 0.11 2.22 0 5.00
95 INT263914 Binding of TMED7-TICAM2 1 0.01 1.56 0 5.00
96 INT174197 Negative_regulation of Gene_expression of RB1 4 0.47 4.25 0 5.00
97 INT263910 Regulation of SLN 1 0.15 1.01 0 5.00
98 INT263883 Localization of Rigs1 1 0.08 2.36 0 5.00
99 INT263881 Binding of Rigs1 1 0.04 0.99 0 5.00
100 INT231978 Binding of SERPINB3 9 0.36 8.33 0 5.00
101 INT263876 Negative_regulation of Rigs1 1 0.04 0.98 0 5.00
102 INT350741 Binding of RNF123 1 0.01 1.15 0 5.00
103 INT235661 Gene_expression of D4S234E 2 0.23 0.58 0 5.00
104 INT263909 Positive_regulation of Gene_expression of TMED7-TICAM2 1 0.01 0.87 0 5.00
105 INT263880 Regulation of Gene_expression of Rigs1 1 0.05 0.48 0 5.00
106 INT263915 Binding of SLN 2 0.12 0.81 0 5.00
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