D:Wallerian Degeneration

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Disease Term
Synonyms Degeneration Wallerian
Documents 187
Hot Single Events 188
Hot Interactions 7

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Wallerian Degeneration. They are ordered first by their relevance to Wallerian Degeneration and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT293617 Wld Positive_regulation of Nmnat2 1 0.65 1.9 0 100.00
2 INT293615 Nmnat2 Positive_regulation of Nmnat1 1 0.19 0.79 0 100.00
3 INT293613 Wld Positive_regulation of Nmnat1 1 0.42 0.79 0 100.00
4 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04 99.92
5 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82 95.64
6 INT184827 Binding of Thy1 and Tg(CAG-EGFP)D4Nagy 1 0.06 0.18 0.07 83.72
7 INT101087 NTF3 Positive_regulation of Gene_expression of IKZF1 1 0.04 0.3 0.55 80.52
8 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78 75.36
9 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77 75.36
10 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96 75.00
11 INT133651 Epo Regulation of TNF 1 0.50 1.25 0.38 75.00
12 INT133653 Epo Regulation of Transcription of TNF 1 0.22 1.09 0.33 75.00
13 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78 74.64
14 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75 74.64
15 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 74.48
16 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78 73.76
17 INT193550 Ephb1 Positive_regulation of Gene_expression of Bdnf 1 0.29 0.3 0.14 64.88
18 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49 62.52
19 INT211996 Erbb3 Positive_regulation of Nrg1 2 0.03 0.67 0.11 58.84
20 INT308170 Binding of thd and Tnfrsf14 1 0.00 1.84 0.46 54.56
21 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11 53.20
22 INT308171 Binding of TNF and thd 1 0.00 1.84 0.45 53.20
23 INT275396 Binding of NDRG1 and Htatsf1 1 0.00 0.65 0.14 47.60
24 INT275392 Binding of Gap43 and Htatsf1 1 0.01 0.64 0.13 47.60
25 INT275391 Binding of Atf3 and Htatsf1 1 0.02 0.64 0.13 47.60
26 INT275389 Binding of Casp3 and Htatsf1 1 0.00 0.64 0.13 47.60
27 INT275375 Binding of ITIH4 and NDRG1 1 0.00 0.65 0.14 47.36
28 INT275401 Binding of ITIH4 and Atf3 1 0.12 0.64 0.13 47.36
29 INT275408 Binding of ITIH4 and Gap43 1 0.03 0.64 0.13 47.36
30 INT275397 Binding of ITIH4 and Casp3 1 0.02 0.64 0.13 47.36
31 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58 42.96
32 INT193553 Mtpn Positive_regulation of Ephb1 1 0.04 0.34 0.13 14.56
33 INT193548 Gdnf Positive_regulation of Ephb1 1 0.40 0.34 0.13 14.56
34 INT193551 Mtpn Positive_regulation of Gene_expression of Gdnf 1 0.02 0.34 0.13 14.24
35 INT193552 Gdnf Positive_regulation of Gene_expression of Mtpn 1 0.02 0.34 0.13 14.24
36 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66 5.00
37 INT275398 Binding of ITIH4 and Htatsf1 1 0.02 5.05 2.24 5.00
38 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
39 INT190128 Positive_regulation of PTGER1 Negative_regulation of Gene_expression of CPOX 1 0.04 1.21 1.38 5.00
40 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23 5.00
41 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 5.00
42 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 5.00
43 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 5.00
44 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97 5.00
45 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97 5.00
46 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97 5.00
47 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97 5.00
48 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95 5.00
49 INT274785 S100B Positive_regulation of Ngf 1 0.05 0.61 0.8 5.00
50 INT274786 Ngf Positive_regulation of Gene_expression of S100B 1 0.05 0.63 0.71 5.00
51 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 5.00
52 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61 5.00
53 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61 5.00
54 INT173806 Ngf Regulation of Gene_expression of Pou2f2 1 0.04 0.17 0.58 5.00
55 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56 5.00
56 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55 5.00
57 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54 5.00
58 INT355878 Il17a Regulation of Eae1 1 0.06 1.52 0.54 5.00
59 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54 5.00
60 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54 5.00
61 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53 5.00
62 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53 5.00
63 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52 5.00
64 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52 5.00
65 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52 5.00
66 INT193554 Ntrk2 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.73 0.52 5.00
67 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52 5.00
68 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5 5.00
69 INT275407 Binding of ERVW-1 and Ccr5 1 0.00 1.74 0.46 5.00
70 INT275399 Binding of ERVW-1 and Cxcr4 1 0.00 1.73 0.46 5.00
71 INT298999 Binding of Il18bp and Il18 1 0.02 0 0.45 5.00
72 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45 5.00
73 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43 5.00
74 INT274781 Agrn Positive_regulation of Chrna2 1 0.08 0.18 0.41 5.00
75 INT275402 Trpv1 Regulation of Gene_expression of NDRG1 1 0.00 1.25 0.39 5.00
76 INT221637 Binding of Plxna1 and Fer 1 0.01 0.59 0.36 5.00
77 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29 5.00
78 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29 5.00
79 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29 5.00
80 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29 5.00
81 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29 5.00
82 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27 5.00
83 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25 5.00
84 INT299013 Il18 Regulation of Ltp 1 0.05 0.39 0.25 5.00
85 INT298993 Il2 Positive_regulation of Gene_expression of Il13 1 0.01 0.73 0.24 5.00
86 INT299003 Il18 Positive_regulation of Gene_expression of Il13 1 0.11 0.73 0.24 5.00
87 INT275404 ITIH4 Regulation of Positive_regulation of Htatsf1 1 0.02 0.91 0.22 5.00
88 INT355877 Binding of Hand1 and Il4 1 0.14 0.25 0.22 5.00
89 INT299000 Positive_regulation of Il18 Regulation of Ltp 1 0.05 0.35 0.2 5.00
90 INT221642 Binding of Fes and Fer 1 0.32 0.27 0.2 5.00
91 INT221627 Binding of Dpysl2 and Fer 1 0.21 0.27 0.2 5.00
92 INT221641 Binding of Dpysl2 and Fes 1 0.23 0.27 0.2 5.00
93 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18 5.00
94 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18 5.00
95 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17 5.00
96 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17 5.00
97 INT193546 Il1b Positive_regulation of Ephb1 1 0.12 0.35 0.16 5.00
98 INT221656 Plxna1 Negative_regulation of Fer 1 0.02 0.59 0.15 5.00
99 INT221632 Plxna1 Negative_regulation of Fes 1 0.02 0.58 0.15 5.00
100 INT275374 JUN Positive_regulation of NDRG1 1 0.00 1.35 0.15 5.00
101 INT329985 Positive_regulation of Prkaca Positive_regulation of Positive_regulation of Mapk14 1 0.15 0.87 0.15 5.00
102 INT299012 Binding of Il18bp and Il1f5 1 0.00 0 0.14 5.00
103 INT221662 Fes Positive_regulation of Phosphorylation of Dpysl2 1 0.24 0.14 0.14 5.00
104 INT221615 Dpysl2 Positive_regulation of Gene_expression of Fes 1 0.21 0.14 0.13 5.00
105 INT221636 Dpysl2 Positive_regulation of Fer 1 0.21 0.14 0.13 5.00
106 INT221620 Fes Regulation of Gh 1 0.01 0.39 0.12 5.00
107 INT221665 Fes Regulation of Sema3a Regulation of Gh 1 0.01 0.39 0.12 5.00
108 INT208207 Binding of Cadm1 and Pvrl3 1 0.12 1.06 0.12 5.00
109 INT221634 Fes Regulation of Ngf 1 0.28 0.33 0.12 5.00
110 INT221628 Sema3a Regulation of Gh 1 0.01 0.39 0.12 5.00
111 INT221659 Binding of Fes and Dpysl5 1 0.16 0.58 0.11 5.00
112 INT299015 Binding of FAS and Il18 1 0.38 0.83 0.11 5.00
113 INT221625 Fer Regulation of Localization of Sema3a 1 0.24 0.29 0.1 5.00
114 INT298994 Binding of Il18 and Il1f5 1 0.01 0 0.1 5.00
115 INT221618 Binding of Ngf and Fer 1 0.23 0.6 0.09 5.00
116 INT221668 Sema3a Positive_regulation of NPAT 1 0.36 0.47 0.09 5.00
117 INT221614 Binding of Sema3a and Fer 1 0.30 0.61 0.09 5.00
118 INT221652 Ngf Positive_regulation of Ngrn 1 0.01 0.35 0.09 5.00
119 INT299002 Negative_regulation of Binding of Il18bp and Il18 1 0.02 0 0.08 5.00
120 INT221653 Binding of Myc and Gopc 2 0.12 0.51 0.08 5.00
121 INT221655 Plxna1 Negative_regulation of Phosphorylation of Fes 1 0.02 0.17 0.08 5.00
122 INT355879 Binding of Sry and Eae1 1 0.05 1.34 0.07 5.00
123 INT299009 Il1f5 Negative_regulation of Il18 1 0.01 0 0.07 5.00
124 INT221631 Dpysl2 Negative_regulation of Fes 1 0.21 0.42 0.07 5.00
125 INT221646 Dpysl2 Negative_regulation of Fer 1 0.08 0.42 0.07 5.00
126 INT221619 Binding of Ngf and Sema3a 1 0.17 0.54 0.06 5.00
127 INT221658 Sema3a Positive_regulation of Phosphorylation of Crmp1 1 0.12 0.4 0.05 5.00
128 INT221657 Sema3a Positive_regulation of Binding of Plxna1 1 0.01 0.39 0.05 5.00
129 INT221663 Fes Positive_regulation of Binding of Plxna1 1 0.02 0.4 0.05 5.00
130 INT208211 Binding of Pira1 and Cadm2 1 0.00 0.15 0.04 5.00
131 INT221654 Fes Positive_regulation of Phosphorylation of Crmp1 1 0.18 0.37 0.04 5.00
132 INT208208 Binding of Pira1 and Cadm1 1 0.02 0.15 0.04 5.00
133 INT221639 Fyn Positive_regulation of Phosphorylation of Cdk5 1 0.14 0.28 0.03 5.00
134 INT221647 Negative_regulation of Gopc Regulation of Ngf 1 0.07 0.13 0.03 5.00
135 INT221624 Binding of Fyn and Plxna1 1 0.01 0.29 0.03 5.00
136 INT221661 Sema3a Positive_regulation of Phosphorylation of Cdk5 1 0.19 0.28 0.03 5.00
137 INT221640 Sema3a Positive_regulation of Phosphorylation of Fyn 1 0.16 0.29 0.03 5.00
138 INT221651 Binding of Fyn and Plxna2 1 0.01 0.29 0.03 5.00
139 INT221623 Fyn Regulation of Fes 1 0.14 0.2 0.03 5.00
140 INT221626 Gopc Regulation of Sema3a 1 0.06 0.13 0.03 5.00
141 INT221667 Fer Regulation of Gopc Regulation of Ngf 1 0.04 0.13 0.03 5.00
142 INT221660 Gopc Regulation of Ngf 1 0.04 0.13 0.03 5.00
143 INT221613 Binding of Cdk5 and Fyn 1 0.10 0.29 0.03 5.00
144 INT221666 Sema3a Positive_regulation of Fyn Positive_regulation of Cdk5 1 0.10 0.29 0.03 5.00
145 INT221617 Fyn Positive_regulation of Cdk5 1 0.13 0.28 0.03 5.00
146 INT299006 Binding of Il18 and Myd88 1 0.21 0.19 0.03 5.00
147 INT221621 Binding of Lat and Fer 1 0.02 0 0 5.00
148 INT221644 Binding of Nptx1 and Sema3a 1 0.12 0.19 0 5.00
149 INT221648 Binding of Myc and Sh2 1 0.05 0 0 5.00
150 INT221650 Binding of Plec and Fer 1 0.08 0 0 5.00
151 INT221633 Binding of Akt1 and Plxna1 1 0.00 0 0 5.00
152 INT208209 Binding of Gapdh and Cadm1 1 0.36 0.09 0 5.00
153 INT221616 Binding of Dpysl2 and Sh2 1 0.06 0 0 5.00
154 INT221629 Dpysl2 Negative_regulation of Phosphorylation of Fer 1 0.18 0 0 5.00
155 INT221622 Dpysl2 Positive_regulation of Fes 1 0.24 0 0 5.00
156 INT221664 Binding of Ctnnd1 and Fer 1 0.33 0 0 5.00
157 INT266098 Bdnf Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.05 0.41 0 5.00
158 INT221638 Binding of Nrp1 and Sema3a 1 0.05 0.38 0 5.00
159 INT221645 Fyn Regulation of Phosphorylation of Fer 1 0.12 0.08 0 5.00
160 INT221635 Dpysl2 Negative_regulation of Phosphorylation of Fes 1 0.20 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Wallerian Degeneration. They are ordered first by their pain relevance and then by number of times they were reported in Wallerian Degeneration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT140003 Gene_expression of Wld 4 0.74 10.75 0.87 100.00
2 INT270032 Gene_expression of Nmnat1 2 0.72 7.19 0.15 100.00
3 INT293584 Positive_regulation of Wld 1 0.66 2.71 0.31 100.00
4 INT293609 Negative_regulation of Gene_expression of Wld 1 0.41 1.73 0 100.00
5 INT293605 Binding of Wld 1 0.36 0.87 0 100.00
6 INT293604 Negative_regulation of Wld 1 0.56 0.83 0 100.00
7 INT48240 Binding of Ngf 46 0.46 23.51 24.42 100.00
8 INT293596 Positive_regulation of Gene_expression of Nmnat2 1 0.46 0.95 0 100.00
9 INT293603 Localization of Wld 1 0.62 0.78 0 100.00
10 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65 100.00
11 INT293594 Positive_regulation of Nmnat1 1 0.57 1.41 0 99.98
12 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4 99.96
13 INT242559 Gene_expression of Kpnb1 6 0.07 9.27 0.81 99.92
14 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 99.90
15 INT89660 Positive_regulation of Gene_expression of Hrec 15 0.17 12.06 7.37 99.90
16 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 99.88
17 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 99.88
18 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 99.88
19 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68 99.88
20 INT293588 Gene_expression of Nmnat2 1 0.76 8.52 0.21 99.84
21 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 99.84
22 INT293580 Protein_catabolism of Nmnat2 1 0.97 0.97 0 99.84
23 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.84
24 INT293610 Transcription of Nmnat2 1 0.45 0.54 0 99.84
25 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9 99.84
26 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 99.76
27 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 99.70
28 INT53574 Regulation of Tnf 45 0.62 40.68 19.71 99.68
29 INT111520 Regulation of Tnfrsf1a 10 0.61 7.25 5.41 99.68
30 INT124974 Regulation of Tnfrsf1b 4 0.59 4.59 3.01 99.68
31 INT293581 Positive_regulation of Nmnat2 1 0.59 4.33 0.86 99.66
32 INT48892 Transcription of Il10 31 0.71 27.26 16.77 99.64
33 INT293592 Negative_regulation of Nmnat2 1 0.50 8.75 0 99.52
34 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 99.48
35 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 99.44
36 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 99.44
37 INT51028 Regulation of Il1b 28 0.60 21.15 12.47 99.44
38 INT94744 Regulation of Transcription of Il1b 3 0.44 2.83 1.26 99.44
39 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78 99.44
40 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44 99.44
41 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.36
42 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.36
43 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7 99.36
44 INT293585 Localization of Nmnat1 1 0.75 2.74 0 99.24
45 INT66926 Transcription of Il1b 15 0.69 13.16 7.81 99.24
46 INT66922 Positive_regulation of Transcription of Il1b 7 0.49 6.58 3.14 99.24
47 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29 99.24
48 INT293591 Regulation of Localization of Nmnat1 1 0.37 0.77 0 99.24
49 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.24
50 INT293600 Localization of Nmnat3 1 0.64 0.74 0 99.22
51 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.18
52 INT49986 Transcription of Tnf 25 0.72 18.3 16.22 99.12
53 INT270031 Positive_regulation of Gene_expression of Nmnat1 2 0.65 1.73 0.06 99.08
54 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.98
55 INT293577 Protein_catabolism of Nefh 1 0.19 1.85 0.08 98.92
56 INT47061 Negative_regulation of Pid1 2 0.48 4.71 4.57 98.92
57 INT293612 Negative_regulation of Nmnat1 1 0.35 0.46 0 98.88
58 INT293598 Negative_regulation of Binding of Nmnat2 1 0.36 1.3 0 98.82
59 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 98.76
60 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 98.76
61 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 98.76
62 INT293608 Binding of Nmnat2 1 0.32 2.8 0 98.68
63 INT293583 Gene_expression of Nmnat3 1 0.48 1.13 0 98.64
64 INT293611 Localization of Nmnat2 1 0.69 3.12 0.08 98.62
65 INT98017 Protein_catabolism of Gtf3a 10 0.11 6.16 0.83 98.58
66 INT35406 Localization of Tnf 94 0.81 64.63 31.65 98.44
67 INT10166 Localization of Tnf 237 0.81 153.95 88.64 98.44
68 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 98.44
69 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 98.32
70 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 98.20
71 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 97.76
72 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 97.56
73 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8 97.52
74 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28 97.24
75 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 96.50
76 INT293590 Negative_regulation of Localization of Nefh 1 0.10 0.69 0 96.48
77 INT293578 Negative_regulation of Protein_catabolism of Nefh 1 0.11 0.69 0 96.48
78 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 96.48
79 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 96.32
80 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 96.32
81 INT48654 Negative_regulation of Gene_expression of GAL 5 0.42 2.14 2.56 96.32
82 INT74156 Positive_regulation of Il12b 3 0.49 1.54 2.04 96.28
83 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 96.16
84 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98 96.16
85 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 96.16
86 INT145514 Localization of Nefh 5 0.32 2.23 0.72 96.08
87 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 95.72
88 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 95.36
89 INT259760 Localization of Fbn2 5 0.05 5.55 2.85 95.32
90 INT81194 Binding of CPOX 40 0.29 23.7 18.95 94.88
91 INT23128 Binding of PTGER1 4 0.27 1.82 2.45 94.88
92 INT124705 Binding of Il18 29 0.47 19.02 5.59 94.84
93 INT198753 Binding of Psd 18 0.20 1.66 2.84 94.80
94 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48 94.68
95 INT242561 Positive_regulation of Kpnb1 2 0.05 1.96 0.29 94.56
96 INT14732 Positive_regulation of FN1 46 0.69 31.17 7.33 94.48
97 INT15850 Positive_regulation of Trim25 4 0.43 5.64 2.52 94.12
98 INT4868 Gene_expression of GAL 75 0.78 22.23 29.02 93.76
99 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03 93.76
100 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 93.32
101 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2 93.12
102 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 92.96
103 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53 92.64
104 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63 92.64
105 INT194058 Localization of Gpx6 9 0.06 2.35 0.46 92.08
106 INT67457 Binding of Rara 12 0.24 8.28 1.45 91.12
107 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 90.60
108 INT293601 Binding of Nmnat3 1 0.30 1.58 0 90.08
109 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 90.08
110 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86 89.88
111 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 89.88
112 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 89.88
113 INT74153 Transcription of Eif3h 1 0.12 0.57 0.5 89.80
114 INT29668 Regulation of PTGER1 9 0.45 5.52 4.5 89.68
115 INT74155 Transcription of Il12b 3 0.60 1.45 0.66 89.28
116 INT52937 Gene_expression of Cd68 37 0.67 31.33 7.54 89.24
117 INT293586 Binding of Nmnat1 1 0.35 1.78 0 89.20
118 INT67398 Transcription of Il12a 3 0.26 3.16 1.49 89.04
119 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24 89.00
120 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 88.76
121 INT275378 Gene_expression of Rilp 1 0.01 0.75 0.12 88.64
122 INT50196 Transcription of Il1b 25 0.69 19.08 10.43 88.36
123 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 88.28
124 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 88.28
125 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 88.24
126 INT13354 Transcription of TNF 108 0.72 85.81 42.32 88.12
127 INT71766 Transcription of Il10 31 0.69 24.66 10.78 88.12
128 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 88.12
129 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 88.12
130 INT97438 Transcription of Il4 17 0.67 9.17 3.4 88.12
131 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 87.92
132 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 87.92
133 INT266561 Negative_regulation of Positive_regulation of Sorbs1 1 0.01 1.01 0.88 87.92
134 INT158313 Positive_regulation of Psd 3 0.39 1.96 0.43 87.40
135 INT74154 Transcription of Ifng 14 0.67 10.33 6.21 87.20
136 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 86.96
137 INT293582 Negative_regulation of Positive_regulation of Nmnat2 1 0.36 0.78 0.26 86.56
138 INT19511 Localization of Il6 212 0.81 118.17 67.67 85.96
139 INT82882 Localization of Ccl2 61 0.80 41.96 28 85.96
140 INT5966 Localization of Il1a 50 0.78 22.91 26.54 85.96
141 INT79553 Localization of Il12a 9 0.31 5.85 3.16 85.96
142 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 85.76
143 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24 85.76
144 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66 85.68
145 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 85.68
146 INT234081 Gene_expression of Vamp2 9 0.51 0.71 0.94 85.68
147 INT336691 Regulation of Gene_expression of Vamp2 1 0.19 0.43 0.03 85.68
148 INT34904 Negative_regulation of Gtf3a 48 0.15 38.88 13.73 85.56
149 INT74157 Negative_regulation of Positive_regulation of Il10 5 0.43 5.83 3.56 85.24
150 INT163395 Positive_regulation of Pid1 1 0.41 1.2 1.36 85.00
151 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 84.80
152 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35 84.80
153 INT100965 Positive_regulation of Nav1 85 0.70 37.74 75.35 84.28
154 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9 84.24
155 INT39046 Positive_regulation of PTGER1 28 0.69 18.18 13.21 84.16
156 INT190133 Positive_regulation of Positive_regulation of PTGER1 1 0.34 0.86 0.68 84.16
157 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 83.60
158 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78 83.60
159 INT293589 Positive_regulation of Localization of Nmnat2 1 0.43 0.17 0 83.52
160 INT74838 Positive_regulation of Sorbs1 18 0.34 6.93 12.63 83.36
161 INT88464 Negative_regulation of CST7 11 0.31 5.33 2.17 83.28
162 INT140002 Positive_regulation of Gene_expression of Wld 1 0.56 0.65 0.32 83.00
163 INT68974 Localization of Mmp9 10 0.80 4.84 3.35 82.72
164 INT102158 Protein_catabolism of Mmp9 7 0.65 5.43 1.91 82.72
165 INT140000 Positive_regulation of Gene_expression of Nmnat1 1 0.26 0.33 0.16 82.68
166 INT140001 Gene_expression of Nmnat1 1 0.40 0.33 0.16 82.68
167 INT96443 Gene_expression of KNCN 4 0.56 2.49 2.22 82.56
168 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 82.40
169 INT184825 Regulation of Thy1 7 0.42 4.14 0.28 82.20
170 INT293597 Negative_regulation of Negative_regulation of Nmnat2 1 0.36 0.15 0 82.08
171 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 81.92
172 INT49610 Positive_regulation of Gene_expression of CTS 7 0.43 7.45 3.58 81.92
173 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 81.76
174 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 81.68
175 INT77152 Positive_regulation of Positive_regulation of H2-K1 2 0.26 1.12 0.64 81.04
176 INT4756 Positive_regulation of Nrtim1 37 0.33 14.6 24.12 80.96
177 INT266562 Gene_expression of Fbn2 1 0.05 0.93 0.84 80.96
178 INT266563 Positive_regulation of Gene_expression of Fbn2 1 0.04 0.93 0.84 80.96
179 INT127853 Localization of Ephb1 20 0.74 5.47 7.96 80.92
180 INT193543 Localization of Dynll1 1 0.68 0.17 0.07 80.92
181 INT11476 Positive_regulation of H2-K1 17 0.26 9.48 2.23 80.76
182 INT346446 Negative_regulation of Regulation of Atf3 1 0.38 0.58 0.39 80.68
183 INT293599 Positive_regulation of Negative_regulation of Nmnat2 1 0.43 1.02 0 80.48
184 INT6852 Localization of TNF 883 0.81 705.95 270.84 80.48
185 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04 80.32
186 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 80.32
187 INT149349 Regulation of Atf3 8 0.45 10 3.85 80.28
188 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 80.08
189 INT101090 Gene_expression of IKZF1 6 0.77 2.98 1.58 79.88
190 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12 79.76
191 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19 79.72
192 INT67253 Gene_expression of Pmp22 4 0.33 6.48 1.79 79.72
193 INT148293 Positive_regulation of Gene_expression of Pmp22 1 0.30 1.58 0.92 79.72
194 INT103230 Gene_expression of Btnl2 17 0.75 8.55 4.77 79.64
195 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 79.60
196 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23 79.60
197 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67 79.44
198 INT293606 Negative_regulation of Gene_expression of Nmnat2 1 0.42 0.54 0.09 79.36
199 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 79.32
200 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 79.16
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