D:Weight Gain

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pChart

Disease Term
Synonyms Gain Weight, Gains Weight, Weight Gains
Documents 2140
Hot Single Events 200
Hot Interactions 34

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Weight Gain. They are ordered first by their relevance to Weight Gain and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT264661 ESR1 Positive_regulation of PRL 1 0.43 0.68 0 98.56
2 INT289541 Sirt1 Regulation of Gene_expression of Agrp 1 0.41 0.52 0.04 97.56
3 INT123556 Shfm1 Regulation of Mpo 1 0.09 0.88 0.76 96.20
4 INT128943 Pomc Regulation of Npy 1 0.23 0.61 0.81 96.12
5 INT242025 Binding of CRP and CHDH 7 0.18 15.72 0.36 95.96
6 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 95.84
7 INT328296 GHRH Negative_regulation of Localization of GH1 1 0.03 0.84 0 95.84
8 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29 95.56
9 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29 95.56
10 INT332978 ACOX1 Negative_regulation of Transcription of Apoc3 1 0.00 0.98 0 95.56
11 INT332962 Acaa1a Negative_regulation of Transcription of Apoc3 1 0.01 0.93 0 95.00
12 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 94.88
13 INT105877 Positive_regulation of Binding of Ins1 and Oprm1 1 0.21 0.67 0.28 94.60
14 INT105872 Binding of Ins1 and Oprm1 1 0.16 0.58 0.27 94.60
15 INT304813 Binding of MNX1 and RT1-CE1 1 0.00 0.34 0.1 90.28
16 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94 90.24
17 INT282330 Binding of DST and Arc 1 0.04 1.1 0 88.68
18 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37 88.32
19 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52 87.80
20 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52 87.80
21 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 87.60
22 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16 87.28
23 INT352579 CNTF Negative_regulation of Gene_expression of NPY 1 0.17 0.89 0.07 87.28
24 INT285341 Mtx1 Regulation of Gene_expression of Tnf 1 0.03 0.78 0.22 84.52
25 INT285340 Mtx1 Regulation of Tnf 1 0.03 0.78 0.22 84.52
26 INT285342 Mtx1 Regulation of Il10 1 0.03 0.78 0.22 84.52
27 INT285343 Mtx1 Regulation of Il6 1 0.04 0.78 0.22 84.52
28 INT289518 Arc Regulation of Sirt1 1 0.10 0.56 0 84.44
29 INT314623 Ex Positive_regulation of INS 1 0.10 1.46 0 84.04
30 INT81735 Binding of Ins1 and Pomc 1 0.20 2.24 0.71 82.72
31 INT345966 Binding of Arid1a and al44 1 0.00 1.56 0.05 82.00
32 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05 82.00
33 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4 81.92
34 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2 80.36
35 INT305163 Ins1 Positive_regulation of Phosphorylation of Olfr473 1 0.01 1.02 0 79.40
36 INT246466 GHS Positive_regulation of GHS Regulation of Gh 1 0.01 0.6 0.1 79.24
37 INT311229 DPP4 Positive_regulation of Gene_expression of INS 1 0.32 0.57 0 79.16
38 INT246468 GHS Regulation of Gh 1 0.05 1.12 0.19 78.92
39 INT343571 Synm Positive_regulation of ALPP 1 0.01 1.28 0.28 77.92
40 INT343570 Synm Positive_regulation of Gpt 1 0.01 1.28 0.28 77.92
41 INT343573 Synm Positive_regulation of SLC17A5 1 0.17 1.28 0.28 77.92
42 INT343572 Negative_regulation of Synm Positive_regulation of SLC17A5 1 0.16 0.44 0 77.92
43 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78 76.44
44 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77 76.44
45 INT332268 Binding of Cndp2 and Tenc1 1 0.05 0.17 0 74.60
46 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31 74.52
47 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31 74.52
48 INT296113 Fig4 Negative_regulation of Gene_expression of Csf2 1 0.01 0.91 0.04 72.32
49 INT296115 Fig4 Negative_regulation of Csf2 1 0.01 0.91 0.04 72.32
50 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 70.40
51 INT306947 NAMPT Regulation of INS 1 0.13 1.41 0 70.20
52 INT246467 GHS Regulation of Localization of Gh 1 0.03 0.52 0.09 70.12
53 INT229711 Positive_regulation of Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05 69.92
54 INT229712 Nr4a3 Regulation of Ins1 1 0.01 0.29 0.05 69.92
55 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 69.68
56 INT300486 LEP Positive_regulation of ROS1 1 0.15 0.91 0.09 69.12
57 INT317247 Ffar1 Positive_regulation of Localization of Gpr119 1 0.10 0.12 0.06 68.64
58 INT317249 Gpr119 Positive_regulation of Localization of Ffar1 1 0.10 0.12 0.06 68.64
59 INT236147 Binding of Ins1 and Ptpn1 2 0.03 1.29 0.05 68.56
60 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 67.60
61 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 67.60
62 INT233907 Positive_regulation of Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08 67.32
63 INT266811 Binding of HRH1 and HTR2C 1 0.23 2.06 1.4 67.28
64 INT214167 Binding of DST and Pomc 1 0.03 0.22 0.03 67.04
65 INT214171 Binding of DST and Cartpt 1 0.01 0.21 0.03 67.04
66 INT233906 Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08 67.00
67 INT126922 Ins1 Positive_regulation of Localization of Slc2a4 1 0.23 0.75 0.11 65.84
68 INT184098 Binding of Il4 and Socs5 1 0.09 2.05 0.15 65.60
69 INT214149 Binding of Lepr and Pomc 1 0.33 0.21 0.03 65.52
70 INT214148 Binding of Lepr and Cartpt 1 0.09 0.21 0.03 65.52
71 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09 63.68
72 INT240872 Ins1 Negative_regulation of Gene_expression of Ppargc1a 1 0.13 0.47 0.14 62.64
73 INT184137 Binding of Socs5 and Regulation of Hand2 1 0.09 1.01 0 61.96
74 INT316203 Ghsr Positive_regulation of Transcription of Agrp 1 0.02 1.5 0.19 61.88
75 INT129313 HTR2A Positive_regulation of Oxt 1 0.41 0.22 0.67 61.72
76 INT303445 Mmp3 Positive_regulation of Mmp9 1 0.01 1.19 0.47 61.56
77 INT334786 Bbaa12 Positive_regulation of Positive_regulation of Angptl4 1 0.13 0.21 0.08 59.96
78 INT184093 Negative_regulation of Il4 Positive_regulation of Stat6 1 0.08 0.93 0 59.28
79 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 58.76
80 INT202619 Binding of Ppara and Spna1 1 0.01 0.27 0.1 58.52
81 INT332269 Cndp2 Negative_regulation of Tenc1 1 0.41 0.8 0.05 58.28
82 INT56633 Gusb Regulation of Mgst1 1 0.03 0.06 0.24 57.92
83 INT56632 Ugt2b17 Regulation of Mgst1 1 0.04 0.06 0.24 57.92
84 INT289600 Negative_regulation of Binding of Sirt1 and Sirt1 1 0.47 1.17 0 57.84
85 INT289598 Binding of Sirt1 and Sirt1 1 0.41 1.15 0 57.84
86 INT184108 Csf3 Positive_regulation of Mapk1 1 0.09 0.64 0.08 57.36
87 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 57.28
88 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04 57.16
89 INT69206 Ntf3 Negative_regulation of Ntf3 Positive_regulation of Penk 1 0.05 0.06 0.66 55.84
90 INT69205 Ntf3 Positive_regulation of Penk 1 0.06 0.06 0.66 55.84
91 INT335025 Gm7647 Positive_regulation of Gene_expression of Fgf21 1 0.01 0.29 0.21 54.68
92 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03 54.56
93 INT289606 Sirt1 Negative_regulation of Stat3 Positive_regulation of Stat3 1 0.28 0.31 0.03 54.56
94 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34 54.48
95 INT245332 ATR Regulation of IL6 1 0.03 0.35 0.17 54.36
96 INT311227 INS Negative_regulation of HBA1 1 0.01 0.52 0.16 53.80
97 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08 53.60
98 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05 52.80
99 INT242203 GLP1R Regulation of GCG 1 0.04 0.64 0.1 51.92
100 INT227303 Zbp1 Regulation of Transcription of Baat 1 0.09 1.43 0.08 50.00
101 INT227301 Zbp1 Regulation of Transcription of Ucp1 1 0.19 1.42 0.08 50.00
102 INT227304 Zbp1 Regulation of Transcription of Ucp2 1 0.17 1.43 0.08 50.00
103 INT227305 Zbp1 Regulation of Gene_expression of Adipoq 1 0.21 1.27 0 50.00
104 INT227302 Zbp1 Regulation of Transcription of Adipoq 1 0.09 1.27 0 50.00
105 INT233905 PPARA Positive_regulation of Localization of NCOR2 1 0.01 0.19 0 46.52
106 INT214157 Positive_regulation of Mc3r Regulation of Npy 1 0.14 0.49 0.33 45.92
107 INT233930 Binding of PPARA and Ncoa1 1 0.12 0.19 0 45.72
108 INT233928 PPARA Positive_regulation of Localization of Ncoa1 1 0.18 0.19 0 45.72
109 INT240897 Akt1 Negative_regulation of Positive_regulation of Foxo1 1 0.21 0.22 0.08 45.44
110 INT332627 Positive_regulation of Ins1 Positive_regulation of Phosphorylation of Hk2 1 0.01 0.83 0 45.40
111 INT233927 PPARA Positive_regulation of Ncoa1 1 0.08 0.19 0 45.12
112 INT227556 Ptgds Positive_regulation of Ppara 1 0.18 0.62 0.13 42.92
113 INT242204 DPP4 Positive_regulation of Gene_expression of GLP1R 1 0.03 0.66 0.1 42.08
114 INT275851 PES1 Negative_regulation of CP 1 0.01 1.96 1.83 41.24
115 INT240899 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Foxo1 1 0.14 0.41 0.15 40.48
116 INT268316 Cdk1 Positive_regulation of Mcm3 1 0.28 0.25 0 39.20
117 INT268321 Cdc20 Positive_regulation of Mcm5 1 0.09 0.25 0 39.20
118 INT268318 Cdk1 Positive_regulation of Orc2 1 0.29 0.25 0 39.20
119 INT268320 Cdc20 Positive_regulation of Orc2 1 0.08 0.25 0 39.20
120 INT268319 Cdk1 Positive_regulation of Cdc20 1 0.32 0.25 0 39.20
121 INT268317 Cdk1 Positive_regulation of Mcm7 1 0.33 0.25 0 39.20
122 INT268324 Cdc20 Positive_regulation of Mcm7 1 0.09 0.25 0 39.20
123 INT268323 Cdc20 Positive_regulation of Mcm3 1 0.08 0.25 0 39.20
124 INT268315 Cdk1 Positive_regulation of Mcm5 1 0.33 0.25 0 39.20
125 INT240870 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.2 0.07 38.92
126 INT240877 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Ins1 1 0.03 0.2 0.07 38.92
127 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12 38.72
128 INT256400 GLP1R Positive_regulation of Localization of GCG 1 0.02 0.15 0 38.72
129 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 38.52
130 INT235431 cla Positive_regulation of Ppara 1 0.06 0.6 0 34.96
131 INT18116 NPC1 Negative_regulation of Binding of NPC1 and Oprd1 1 0.13 0 0.54 34.24
132 INT18115 Binding of NPC1 and Oprd1 1 0.11 0 0.54 34.24
133 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11 31.68
134 INT5217 Binding of GRDX and Tas2r124 1 0.11 0.37 0.05 30.48
135 INT5216 Binding of GRDX and Ighg3 1 0.42 0.37 0.05 30.48
136 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 29.20
137 INT214162 Gabrg1 Negative_regulation of Pomc 1 0.05 0.65 0.46 29.12
138 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22 29.12
139 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05 26.76
140 INT328376 Ghrl Negative_regulation of SST 1 0.03 0.13 0.05 26.76
141 INT327809 Binding of ADORA2B and IL8 1 0.03 0.3 0 25.84
142 INT332635 Glp1r Regulation of Localization of Gcg 1 0.03 0.94 0.04 25.04
143 INT332640 Glp1r Regulation of Localization of Ins1 1 0.04 0.52 0.04 25.04
144 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19 23.52
145 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19 23.52
146 INT240881 Gene_expression of Sod1 Positive_regulation of Phosphorylation of Foxo1 1 0.38 0.07 0.03 23.48
147 INT215904 IL36B Regulation of PRL 1 0.01 0.22 0.03 23.36
148 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2 22.24
149 INT240883 Foxo1 Positive_regulation of Ppargc1a 1 0.43 0.06 0.03 18.92
150 INT207555 GH1 Negative_regulation of Phosphorylation of IRS1 1 0.10 0.28 0.03 18.32
151 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05 18.00
152 INT289531 Acsm3 Positive_regulation of Sirt1 1 0.01 0.27 0 17.20
153 INT240894 Gcg Positive_regulation of Creb1 1 0.14 0.06 0.03 16.92
154 INT354097 Timp1 Negative_regulation of Localization of NFKB2 1 0.04 0.94 0 16.12
155 INT354096 Timp1 Negative_regulation of Positive_regulation of NFKB2 1 0.04 0.94 0 16.12
156 INT207554 GH1 Negative_regulation of Phosphorylation of INS 1 0.26 0.28 0.03 16.08
157 INT257397 Binding of FGD1 and INS 1 0.07 0.27 0.21 15.84
158 INT294922 GH1 Positive_regulation of Gene_expression of GHRH 1 0.02 0.2 0 15.12
159 INT257398 Binding of FGD1 and GHRH 1 0.03 0.27 0.2 14.88
160 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22 14.80
161 INT313572 GLP1R Negative_regulation of GCG 1 0.29 0.54 0 14.80
162 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05 14.56
163 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05 14.20
164 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17 12.64
165 INT245329 ATR Negative_regulation of DCD 1 0.10 0.91 0.05 12.28
166 INT245331 ATR Regulation of IL1B 1 0.03 0.91 0.05 12.28
167 INT245330 ATR Regulation of TNF 1 0.04 0.9 0.05 12.28
168 INT207553 GH1 Negative_regulation of INS 1 0.27 0.28 0.03 11.68
169 INT186539 Crh Regulation of Hpse 1 0.09 0.52 0.1 11.52
170 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19 11.44
171 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 10.48
172 INT296114 Il4 Regulation of Gene_expression of Arg1 1 0.00 0.65 0.46 9.88
173 INT260375 Binding of T2 and Htas2 1 0.00 0.18 0 9.64
174 INT229713 Binding of Agt and Ren 1 0.14 0 0 9.36
175 INT229714 Positive_regulation of Binding of Agt and Ren 1 0.18 0 0 9.36
176 INT289526 Binding of Arc and Sirt1 1 0.08 0.55 0.03 9.20
177 INT214151 Gabrg1 Negative_regulation of Gene_expression of Agrp 1 0.04 0.52 0.4 8.64
178 INT214147 Gabrg1 Negative_regulation of Gene_expression of Npy 1 0.03 0.52 0.4 8.64
179 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76 8.36
180 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21 8.24
181 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18 8.24
182 INT281734 MT1JP Positive_regulation of Localization of IL8 1 0.02 0.64 0.3 7.96
183 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76 7.92
184 INT343931 Hapln1 Negative_regulation of Tlr4 1 0.12 0.42 0.25 7.80
185 INT317244 Binding of Npy and Pyy 1 0.26 0 0.05 7.76
186 INT317242 Binding of Tap2 and Npy 1 0.05 0 0.05 7.76
187 INT317246 Binding of Npy2r and Npy 1 0.08 0 0.05 7.76
188 INT303444 Timp1 Regulation of Fig4 1 0.15 0.43 0.39 7.52
189 INT317245 Binding of Npy2r and Pyy 1 0.09 0 0.05 7.12
190 INT317257 Binding of Tap2 and Pyy 1 0.06 0 0.05 7.12
191 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07 6.48
192 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
193 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
194 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
195 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
196 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58 5.00
197 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39 5.00
198 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34 5.00
199 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26 5.00
200 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Weight Gain. They are ordered first by their pain relevance and then by number of times they were reported in Weight Gain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT251 Regulation of INS 398 0.62 232.47 55.04 100.00
2 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 100.00
3 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 100.00
4 INT75908 Regulation of LEP 77 0.60 60.16 15.19 100.00
5 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18 100.00
6 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92 100.00
7 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 100.00
8 INT21067 Regulation of Regulation of PRL 11 0.60 2 5.31 100.00
9 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12 100.00
10 INT181587 Negative_regulation of OPN1SW 12 0.51 4.36 0.89 100.00
11 INT122041 Binding of Ppara 308 0.48 189.17 51.48 99.98
12 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 99.98
13 INT77955 Negative_regulation of PCS 55 0.43 39.32 5.76 99.96
14 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.96
15 INT60187 Positive_regulation of Lbm1 2 0.43 11.43 0.36 99.96
16 INT462 Regulation of Pomc 157 0.62 41.67 67.27 99.96
17 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 99.96
18 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.92
19 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 99.92
20 INT13948 Positive_regulation of Amy1a 2 0.44 2.1 0.91 99.92
21 INT27635 Regulation of Hrtrt1 4 0.03 4.02 0.38 99.92
22 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.90
23 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.90
24 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 99.90
25 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 99.90
26 INT175263 Gene_expression of Ptpro 2 0.65 0.94 0 99.90
27 INT149145 Positive_regulation of Gene_expression of Ang2 4 0.34 27.89 0.78 99.88
28 INT79406 Negative_regulation of Pde4a 20 0.59 25.26 8.35 99.84
29 INT355463 Gene_expression of SPRED1 1 0.56 6.96 0.24 99.84
30 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 99.80
31 INT37111 Regulation of Negative_regulation of Mme 7 0.44 2.61 3.13 99.80
32 INT812 Localization of INS 1026 0.81 515.6 145.31 99.76
33 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.76
34 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.74
35 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 99.72
36 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 99.68
37 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 99.68
38 INT797 Regulation of Penk 812 0.62 111.13 542.24 99.68
39 INT275861 Binding of PES1 1 0.17 3.45 1.95 99.68
40 INT323461 Negative_regulation of Localization of Ghsr 1 0.35 0.76 0.04 99.68
41 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 99.64
42 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03 99.64
43 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36 99.62
44 INT130072 Transcription of Ins1 12 0.54 6.84 0.62 99.60
45 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 99.60
46 INT200442 Positive_regulation of Gene_expression of AES 5 0.42 5.12 0.48 99.60
47 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 99.60
48 INT14572 Binding of INS 205 0.48 175.43 13.38 99.58
49 INT228167 Negative_regulation of Peg10 18 0.02 7.64 0.54 99.58
50 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.54
51 INT74250 Negative_regulation of Gene_expression of Ins1 47 0.40 39.27 5.37 99.46
52 INT227267 Gene_expression of hf 7 0.43 19.8 2.38 99.44
53 INT327474 Positive_regulation of Gene_expression of hf 1 0.23 7.16 0.97 99.44
54 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.44
55 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8 99.44
56 INT183375 Binding of Nppa 14 0.38 8.95 0.51 99.42
57 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.42
58 INT65356 Localization of LEP 46 0.79 41.17 5.43 99.40
59 INT195206 Binding of BCC1 15 0.41 21.3 0.62 99.40
60 INT128555 Positive_regulation of HIST1H1B 5 0.24 1.49 0.07 99.40
61 INT253 Regulation of PRL 184 0.62 47.27 65.79 99.38
62 INT246670 Positive_regulation of Localization of Zglp1 3 0.46 0.98 0.5 99.38
63 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 99.36
64 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.36
65 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.32
66 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 99.30
67 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.28
68 INT242353 Binding of Tcas1 3 0.03 3.31 2.22 99.28
69 INT180971 Protein_catabolism of GOPC 21 0.77 6.15 2.98 99.28
70 INT61714 Binding of FGD1 12 0.35 7.72 2.91 99.26
71 INT127524 Localization of Zglp1 9 0.53 4.28 1.7 99.20
72 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 99.16
73 INT27785 Regulation of HTR2A 11 0.44 8 8.18 99.16
74 INT7366 Negative_regulation of Ghrh 42 0.58 7.72 14.45 99.08
75 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 99.06
76 INT306949 Gene_expression of NAMPT 27 0.67 24.47 2.86 99.04
77 INT2578 Binding of Ins1 74 0.48 33.57 12.92 99.04
78 INT306951 Positive_regulation of Gene_expression of NAMPT 1 0.60 6.08 0.72 99.04
79 INT122924 Binding of ipv 27 0.42 31.81 1.99 99.04
80 INT295519 Localization of Ghsr 7 0.72 0.75 0.68 99.00
81 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 98.98
82 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62 98.98
83 INT242028 Negative_regulation of Negative_regulation of CRP 3 0.43 2.39 0.24 98.98
84 INT327475 Transcription of hf 1 0.32 1.55 0.34 98.94
85 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 98.92
86 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 98.92
87 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 98.92
88 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 98.92
89 INT81733 Transcription of Ins1 9 0.50 6.27 1.41 98.90
90 INT39518 Negative_regulation of HBN1 66 0.09 37.54 2.58 98.88
91 INT291832 Negative_regulation of Gene_expression of hf 2 0.20 1.29 0.25 98.88
92 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 98.84
93 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 98.82
94 INT15775 Positive_regulation of Ren1 50 0.69 22.38 6.19 98.80
95 INT172677 Gene_expression of SHE 65 0.59 25.86 3.85 98.80
96 INT104733 Positive_regulation of Gene_expression of Ren1 24 0.67 43.87 2.47 98.80
97 INT268213 Positive_regulation of Ang2 8 0.08 18.88 0.58 98.80
98 INT268215 Regulation of Gene_expression of Ang2 1 0.05 8.88 0.1 98.80
99 INT230429 Positive_regulation of Gene_expression of SHE 8 0.26 2.75 0.72 98.80
100 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 98.76
101 INT9032 Regulation of Htr2c 11 0.60 2.77 7.81 98.76
102 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07 98.76
103 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26 98.76
104 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 98.74
105 INT124976 Positive_regulation of Tnfrsf1b 15 0.67 14.92 5.15 98.72
106 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2 98.72
107 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79 98.68
108 INT180191 Positive_regulation of Negative_regulation of PCS 2 0.29 3.04 0.03 98.64
109 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 98.56
110 INT28484 Regulation of Cog1 6 0.43 4.96 0.71 98.56
111 INT44661 Regulation of Ahr 15 0.45 12.69 2.79 98.56
112 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03 98.56
113 INT150422 Positive_regulation of Aes 24 0.43 15.63 8 98.56
114 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 98.48
115 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 98.48
116 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 98.44
117 INT8346 Gene_expression of Qrfp 136 0.70 19.49 70.21 98.44
118 INT207293 Negative_regulation of Negative_regulation of INS 12 0.49 6 0.26 98.44
119 INT207088 Localization of Ptpn1 2 0.35 1.48 0.36 98.44
120 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 98.40
121 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 98.40
122 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65 98.40
123 INT110348 Negative_regulation of Dpp4 28 0.46 22.39 4.12 98.40
124 INT246675 Negative_regulation of Glp1r 5 0.55 6.01 0.41 98.40
125 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 98.36
126 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38 98.32
127 INT4437 Positive_regulation of ABCB7 11 0.68 11.26 1.33 98.32
128 INT58875 Positive_regulation of FGD1 20 0.60 3.88 4.19 98.32
129 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 98.28
130 INT15852 Positive_regulation of PSS 7 0.40 4.6 0.67 98.24
131 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 98.16
132 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 98.16
133 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 98.16
134 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 98.16
135 INT355461 Localization of SPRED1 1 0.63 3.48 0.04 98.08
136 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56 98.08
137 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 98.04
138 INT15851 Positive_regulation of Trpv3 11 0.60 4.6 4.35 98.04
139 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 98.00
140 INT103806 Negative_regulation of Aaiq4 4 0.41 3.72 0.31 97.92
141 INT235356 Negative_regulation of Nfix 1 0.51 3.68 0.35 97.84
142 INT44163 Gene_expression of Ren1 69 0.78 97.75 6.27 97.82
143 INT149144 Gene_expression of Ang2 5 0.46 34.27 1.05 97.82
144 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 97.80
145 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 97.76
146 INT62576 Transcription of Creb1 34 0.69 16.97 10.6 97.76
147 INT9100 Negative_regulation of CAMKK2 3 0.48 4.89 0.93 97.72
148 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 97.72
149 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 97.60
150 INT1893 Localization of Gh 1041 0.79 340.23 256.58 97.52
151 INT103094 Binding of PPARA 308 0.47 177.26 34.75 97.52
152 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 97.52
153 INT187618 Localization of Ppara 13 0.70 6.91 3.09 97.48
154 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3 97.36
155 INT14513 Localization of Ghrl 52 0.78 29.26 11.63 97.32
156 INT331744 Positive_regulation of Fat1 10 0.15 4.86 0.03 97.32
157 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 97.32
158 INT331747 Localization of Fat1 3 0.16 1.91 0.03 97.32
159 INT9954 Negative_regulation of Hrh1 16 0.52 13.04 11.76 97.30
160 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 97.26
161 INT137229 Gene_expression of INTU 6 0.59 1.27 0.7 97.24
162 INT27627 Binding of Rac1 41 0.41 22.88 13.68 97.16
163 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03 97.12
164 INT162 Regulation of Prl 794 0.62 165.01 322.24 97.08
165 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84 97.08
166 INT211972 Regulation of Best1 18 0.33 12.04 0.67 97.08
167 INT84888 Binding of PPARD 5 0.48 2.82 1.45 97.08
168 INT327478 Binding of hf 1 0.22 13.2 2.66 97.04
169 INT78995 Negative_regulation of Agtr2 26 0.42 13.05 4.56 97.04
170 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 96.96
171 INT31231 Protein_catabolism of MAOA 7 0.96 2.44 2.4 96.96
172 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 96.92
173 INT196937 Positive_regulation of Hmga2 3 0.68 2.47 0.28 96.92
174 INT18844 Binding of IAPP 11 0.36 11.01 1.45 96.88
175 INT92343 Negative_regulation of CENPJ 20 0.57 6.25 0.2 96.88
176 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 96.80
177 INT123784 Positive_regulation of Gene_expression of Bid 4 0.40 2.41 0.66 96.76
178 INT39468 Positive_regulation of hf 10 0.33 13.5 1.32 96.72
179 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 96.72
180 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 96.68
181 INT14034 Positive_regulation of Gene_expression of Qrfp 18 0.29 1.67 11.17 96.68
182 INT236925 Negative_regulation of Dok1 1 0.21 1.97 0.03 96.68
183 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 96.68
184 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44 96.68
185 INT50444 Negative_regulation of Gene_expression of Alb 11 0.39 7.63 1.06 96.68
186 INT236924 Negative_regulation of Gene_expression of Dok1 1 0.21 0.94 0.03 96.68
187 INT15026 Negative_regulation of Localization of NA 26 0.36 3.76 10.69 96.60
188 INT55332 Regulation of Atr 3 0.32 0.16 0.16 96.56
189 INT142741 Gene_expression of Atp6v1e1 28 0.31 9.41 2.34 96.52
190 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 96.48
191 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 96.48
192 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 96.48
193 INT111365 Positive_regulation of Gene_expression of Cnr2 8 0.70 5.52 6.83 96.48
194 INT10444 Positive_regulation of Gene_expression of CNR1 18 0.69 8.69 7.84 96.48
195 INT18586 Negative_regulation of Regulation of Ins1 8 0.43 2.89 1.15 96.44
196 INT20145 Regulation of Negative_regulation of Ins1 1 0.27 0.68 0.65 96.44
197 INT113734 Gene_expression of Agrp 31 0.77 11.04 9.02 96.40
198 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5 96.40
199 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 96.40
200 INT109833 Binding of GNB3 7 0.48 8.83 2.84 96.40
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