D:Weight Loss

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Disease Term
Synonyms Loss Weight, Losses Weight, Reduction Weight, Reductions Weight, Weight Losses, Weight Reduction, Weight Reductions
Documents 5884
Hot Single Events 200
Hot Interactions 39

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Weight Loss. They are ordered first by their relevance to Weight Loss and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT352503 POMT1 Negative_regulation of FAT1 1 0.00 0.73 0 99.40
2 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54 98.76
3 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1 98.28
4 INT242025 Binding of CRP and CHDH 7 0.18 15.72 0.36 98.16
5 INT276438 Binding of OPN1SW and MYP1 1 0.12 1.21 0.09 98.00
6 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54 97.96
7 INT332633 Glp1r Negative_regulation of Gcg 1 0.04 1.13 0.05 97.88
8 INT332639 Glp1r Negative_regulation of Localization of Gcg 1 0.03 0.87 0.07 97.36
9 INT332632 Gip Negative_regulation of Localization of Gcg 1 0.05 0.47 0.04 97.36
10 INT245329 ATR Negative_regulation of DCD 1 0.10 0.91 0.05 97.20
11 INT60746 Ltbr Negative_regulation of TNF 1 0.16 1.23 0.11 97.16
12 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 97.08
13 INT85531 Rian Negative_regulation of Mpo 1 0.03 1.36 0.27 96.96
14 INT245331 ATR Regulation of IL1B 1 0.03 0.91 0.05 96.64
15 INT280053 Negative_regulation of Dpp4 Negative_regulation of Protein_catabolism of Zglp1 1 0.02 0.71 0.1 96.08
16 INT245330 ATR Regulation of TNF 1 0.04 0.9 0.05 95.84
17 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11 95.76
18 INT260439 Positive_regulation of Binding of IFNA1 and Il6 1 0.01 1.08 0.07 92.16
19 INT260442 Binding of IFNA1 and Il6 1 0.01 1.07 0.07 91.48
20 INT253945 Adrm1 Negative_regulation of Hdl1 1 0.00 1.18 0 90.76
21 INT353062 HSD11B1 Regulation of Gene_expression of ADIPOQ 1 0.13 5.03 0 90.24
22 INT353061 HSD11B1 Regulation of Gene_expression of LEP 1 0.20 5.03 0 90.24
23 INT307704 Binding of Gsr and Rb(8.17)6Sic 1 0.01 1.49 0.03 89.92
24 INT307774 Binding of ARMC9 and RCT 1 0.01 1.27 0 89.20
25 INT281266 Binding of INS and Cyp4a3 1 0.01 0.42 0 88.48
26 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 0.05 1 0.05 87.72
27 INT332628 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Gcg 1 0.05 1 0.05 87.72
28 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5 87.64
29 INT348137 Binding of GYPE and Gpi 1 0.01 1.29 0.29 86.84
30 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 86.64
31 INT230763 GCG Positive_regulation of Localization of INS 1 0.17 0.26 0 86.48
32 INT291041 IL6 Regulation of IL36RN 1 0.00 1.09 0.17 84.32
33 INT332638 Gip Regulation of Glp1r 1 0.02 0.47 0.05 84.08
34 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08 83.80
35 INT352516 Binding of POMT1 and Adipoq 1 0.01 0.4 0 83.28
36 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 83.28
37 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2 82.56
38 INT75318 Gh Regulation of Gene_expression of IGF1 1 0.00 0.26 0 82.32
39 INT231622 Pax3 Positive_regulation of Il17a 1 0.03 1.01 0.19 81.36
40 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 78.24
41 INT281259 Binding of INS and TIMP1 1 0.04 0.27 0 77.60
42 INT65744 Map3k7 Negative_regulation of Gene_expression of Il2 1 0.10 0.74 0.18 77.04
43 INT59379 Calca Negative_regulation of Vip 1 0.12 0.67 0.12 75.72
44 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 75.72
45 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21 75.00
46 INT51720 Negative_regulation of Ins1 Negative_regulation of Igf1 1 0.12 0.85 0.11 74.96
47 INT332825 GCSH Negative_regulation of G6PC 1 0.48 0.25 0 74.20
48 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56 73.84
49 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14 71.20
50 INT183740 Dbi Negative_regulation of A230066D03Rik 1 0.00 0.69 0 70.48
51 INT75319 IGF1 Positive_regulation of Gh 1 0.00 0.26 0 69.12
52 INT260438 Binding of Cd4 and Mx1 1 0.00 1.52 0.29 67.88
53 INT305505 Negative_regulation of Binding of Igfals and Slc17a6 1 0.16 1.12 0.21 67.76
54 INT305510 Binding of Igfals and Slc17a6 1 0.14 1.11 0.21 67.76
55 INT260434 Binding of Cd8a and Mx1 1 0.00 1.52 0.29 67.44
56 INT243315 MTTP Regulation of Gene_expression of CD1A 1 0.02 0.12 0 66.16
57 INT243317 MTTP Regulation of Gene_expression of CD1B 1 0.03 0.12 0 66.16
58 INT243314 MTTP Regulation of Gene_expression of CD1C 1 0.03 0.12 0 66.16
59 INT348220 Glp1r Regulation of Slc2a1 1 0.12 0.66 0.03 65.80
60 INT348225 Glp1r Regulation of Localization of Slc2a4 1 0.36 0.66 0.03 65.80
61 INT348226 Glp1r Regulation of Localization of Slc2a1 1 0.26 1.03 0.03 65.80
62 INT348223 Glp1r Regulation of Positive_regulation of Slc2a4 1 0.26 0.66 0.03 65.80
63 INT348224 Glp1r Regulation of Slc2a4 1 0.26 0.66 0.03 65.80
64 INT233324 SHE Positive_regulation of HIVEP1 1 0.00 2.72 0.14 65.72
65 INT28863 Mtr Negative_regulation of Dhfr 1 0.04 0.87 0.45 64.56
66 INT28864 Mtx1 Negative_regulation of Dhfr 1 0.19 0.87 0.44 64.56
67 INT305508 Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2 64.40
68 INT305511 Negative_regulation of Binding of Sod1 and Slc17a6 1 0.03 1.1 0.2 64.40
69 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09 63.84
70 INT184404 CRP Regulation of Gene_expression of KRT20 1 0.02 1.21 0.24 63.52
71 INT184403 Positive_regulation of GOPC Regulation of Gene_expression of KRT20 1 0.00 1.21 0.24 63.52
72 INT233323 GAD1 Regulation of HMGCR 1 0.09 0.2 0 63.44
73 INT340131 Binding of Fcgrt and Igh-VS107 1 0.29 0.63 0 63.24
74 INT319786 Ccbp2 Positive_regulation of Negative_regulation of Dio1 1 0.09 0.94 0.05 62.60
75 INT249046 Binding of LEP and ARID1B 1 0.01 1.3 0.03 62.20
76 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 61.68
77 INT330620 S100a8 Positive_regulation of Positive_regulation of TNF 1 0.03 1.92 0.32 60.88
78 INT337894 Ins1 Regulation of Gene_expression of Nr2f2 1 0.07 0.22 0.15 59.36
79 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 59.04
80 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18 58.84
81 INT295004 Binding of Pth and Tnfrsf11b 1 0.07 0.06 0 58.08
82 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23 57.12
83 INT245333 ATR Negative_regulation of Protein_catabolism of DCD 1 0.10 0.93 0.14 56.24
84 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37 56.20
85 INT317602 Binding of TNC and PAH 1 0.02 1.74 0 56.04
86 INT258398 Binding of IL6R and JAK1 1 0.01 0.75 0.23 55.16
87 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 54.72
88 INT242657 Fig4 Regulation of Ptger2 1 0.01 0.98 0 54.64
89 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0 54.28
90 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0 54.28
91 INT311225 GLP1R Positive_regulation of Gene_expression of INS 1 0.49 0.33 0.06 53.84
92 INT345289 CRS Regulation of REN 1 0.03 1.02 0.12 52.32
93 INT316203 Ghsr Positive_regulation of Transcription of Agrp 1 0.02 1.5 0.19 52.28
94 INT81179 LEP Regulation of Localization of GH1 1 0.11 0.91 0.12 52.00
95 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35 51.96
96 INT204793 T Positive_regulation of Mthfd1 1 0.00 1.32 0.39 51.68
97 INT322201 Binding of OAP and SLC34A1 1 0.01 1.49 0.77 51.52
98 INT245332 ATR Regulation of IL6 1 0.03 0.35 0.17 51.44
99 INT312950 Binding of ADA and HBN1 1 0.01 0.49 0 50.80
100 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32 50.72
101 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16 50.72
102 INT213160 AGT Positive_regulation of Gene_expression of LEP 1 0.08 1.29 0.03 50.48
103 INT314771 Glp1r Positive_regulation of Gene_expression of Ins1 2 0.04 1.23 0.03 50.20
104 INT5132 GNRH1 Regulation of Lhb 2 0.08 0 0.52 50.00
105 INT300486 LEP Positive_regulation of ROS1 1 0.15 0.91 0.09 50.00
106 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22 49.96
107 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2 49.96
108 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 49.84
109 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48 49.44
110 INT27451 OPRM1 Positive_regulation of Localization of Lhb 1 0.01 0.1 0.41 48.00
111 INT308854 Bcl2a1a Positive_regulation of Gene_expression of HTT 1 0.14 0 0 47.92
112 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18 47.04
113 INT203849 Ass1 Positive_regulation of Casp3 1 0.00 0.71 0.07 44.08
114 INT199436 Binding of Capns1 and Cysltr1 1 0.00 0.79 0.1 43.64
115 INT301632 Binding of Dbi and Fabp1 1 0.13 0.49 0.07 43.28
116 INT301122 Tgm7 Negative_regulation of Akt1 1 0.38 2.78 0.07 41.12
117 INT299725 AFP Positive_regulation of Positive_regulation of ACPP 1 0.00 0.78 0.17 40.52
118 INT256400 GLP1R Positive_regulation of Localization of GCG 1 0.02 0.15 0 40.24
119 INT282330 Binding of DST and Arc 1 0.04 1.1 0 38.00
120 INT267155 Binding of INS and SUGT1 1 0.02 0.81 0.04 36.12
121 INT184405 CRP Positive_regulation of Gene_expression of ASF1A 1 0.03 1.17 0.49 36.00
122 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3 35.80
123 INT263180 Binding of PDE5A and COPD 1 0.01 1 0.15 33.44
124 INT263179 PDE3A Regulation of COPD 1 0.00 1 0.15 33.44
125 INT263178 Binding of PDE7A and COPD 1 0.01 1 0.15 33.44
126 INT263177 Binding of PDE3A and COPD 1 0.01 1 0.15 33.44
127 INT263174 PDE7A Regulation of COPD 1 0.01 1 0.15 33.44
128 INT263176 Binding of PDE4A and COPD 1 0.01 1 0.15 33.44
129 INT263175 PDE5A Regulation of COPD 1 0.00 1 0.15 33.44
130 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16 33.00
131 INT301123 Tgm7 Regulation of Positive_regulation of Mmp2 1 0.23 1.47 0 33.00
132 INT354926 IL6 Regulation of Gene_expression of ALB 1 0.14 1.3 0.23 32.84
133 INT354924 IL6 Positive_regulation of Gene_expression of ALB 1 0.26 1.3 0.23 32.84
134 INT215901 Ins1 Positive_regulation of Igfals 1 0.02 0.81 0.15 32.72
135 INT189108 Mthfd1 Positive_regulation of H2 1 0.00 0.17 0 32.64
136 INT189106 Mthfd1 Positive_regulation of Gene_expression of H2 1 0.00 0.17 0 32.64
137 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69 31.76
138 INT215902 Igfbp2 Positive_regulation of Igfals 1 0.15 0.8 0.15 31.28
139 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11 26.08
140 INT213261 TNF Positive_regulation of CRP 1 0.24 1.59 0.06 26.08
141 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 23.28
142 INT228229 Binding of Cd4 and Ntm 1 0.02 1.03 0.03 22.96
143 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55 22.88
144 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55 22.32
145 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55 22.32
146 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0 21.80
147 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 21.16
148 INT205121 Binding of CD4 and CD7 1 0.05 0.51 0 21.16
149 INT177962 IL4 Positive_regulation of VCAM1 1 0.02 0.97 0.2 21.00
150 INT337884 Ins1 Negative_regulation of Gene_expression of Nr2f2 1 0.11 0.08 0.27 20.16
151 INT319787 Binding of Dio1 and Ccbp2 1 0.06 0.92 0.03 19.76
152 INT254635 Positive_regulation of Eae1 Positive_regulation of Gene_expression of Ccl2 1 0.15 1.07 0.27 18.76
153 INT236585 Ncoa2 Positive_regulation of Transcription of Ncoa1 1 0.27 0.23 0.03 18.32
154 INT189112 Tap1 Positive_regulation of Gene_expression of Mthfd1 1 0.07 0.3 0 18.00
155 INT189114 Mtap1a Positive_regulation of Gene_expression of Mthfd1 1 0.01 0.3 0 18.00
156 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 17.20
157 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 17.20
158 INT185359 Gpt Regulation of PCS 1 0.03 0.33 0.09 17.16
159 INT302926 Binding of Pnp and Pbrm1 1 0.01 0.96 0 16.72
160 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22 15.56
161 INT306945 NAMPT Positive_regulation of Positive_regulation of MAPK1 1 0.10 0.33 0.08 15.08
162 INT232047 Binding of PBRM1 and RNPC3 1 0.05 0.12 0 14.12
163 INT213262 IL6 Positive_regulation of CYP19A1 1 0.11 1.63 0.03 13.84
164 INT232049 PBRM1 Regulation of RNPC3 1 0.04 0.06 0 13.84
165 INT315484 Slfn5 Regulation of Gopc 1 0.05 0.28 0.03 13.80
166 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 13.60
167 INT343027 Binding of CYP3A4 and Azi1 1 0.02 0.75 0.14 13.16
168 INT280846 Crh Positive_regulation of Localization of POMC 1 0.03 0.37 0.16 13.12
169 INT305504 Slc17a6 Positive_regulation of Ex 1 0.05 0.67 0.22 12.64
170 INT301124 Tgm7 Regulation of Akt1 1 0.40 0 0 12.56
171 INT237207 LGALS4 Regulation of Localization of Ik 1 0.00 0.9 1.23 11.80
172 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14 10.88
173 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14 10.08
174 INT239330 Positive_regulation of Ppara Positive_regulation of Hdl1 1 0.05 1.17 0.03 8.80
175 INT302883 Binding of TXN and Alb 1 0.06 4.13 0.1 8.16
176 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 7.68
177 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 7.24
178 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 0.05 1.22 0.29 6.24
179 INT243318 MAPK3 Negative_regulation of FOS 1 0.04 0.14 0 6.16
180 INT302882 Positive_regulation of Binding of TXN and Alb 1 0.05 1.51 0 5.92
181 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03 5.84
182 INT174820 IL6 Positive_regulation of VEGFA 1 0.20 3.32 0.12 5.64
183 INT239338 Arg2 Positive_regulation of RCT 1 0.01 1.15 0.03 5.40
184 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
185 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 5.00
186 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
187 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 5.00
188 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16 5.00
189 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3 5.00
190 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
191 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
192 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
193 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
194 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52 5.00
195 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
196 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
197 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01 5.00
198 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
199 INT275851 PES1 Negative_regulation of CP 1 0.01 1.96 1.83 5.00
200 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Weight Loss. They are ordered first by their pain relevance and then by number of times they were reported in Weight Loss. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 100.00
2 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 100.00
3 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 100.00
4 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 100.00
5 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 100.00
6 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 100.00
7 INT77955 Negative_regulation of PCS 55 0.43 39.32 5.76 100.00
8 INT207568 Negative_regulation of VAT1 1 0.13 8.92 0.55 100.00
9 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 100.00
10 INT341637 Negative_regulation of Atp11a 1 0.13 6.97 0 100.00
11 INT220078 Positive_regulation of Negative_regulation of KNG1 3 0.13 5.03 3.41 100.00
12 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 100.00
13 INT307773 Regulation of Negative_regulation of KNG1 1 0.01 3.59 0.09 100.00
14 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 100.00
15 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 100.00
16 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 100.00
17 INT3167 Binding of KNG1 48 0.48 23.26 26.77 100.00
18 INT4369 Gene_expression of Ldha 157 0.76 88.12 22.45 100.00
19 INT55662 Negative_regulation of Negative_regulation of KNG1 4 0.36 3.45 0.57 100.00
20 INT138216 Negative_regulation of PER1 13 0.37 9.66 4.55 100.00
21 INT137583 Positive_regulation of Ped 3 0.40 2.62 1.75 100.00
22 INT31551 Negative_regulation of Slc25a1 1 0.38 0.72 0.83 100.00
23 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 100.00
24 INT180191 Positive_regulation of Negative_regulation of PCS 2 0.29 3.04 0.03 100.00
25 INT263530 Negative_regulation of Positive_regulation of ADIPOQ 1 0.31 1.43 0 100.00
26 INT82347 Regulation of PLXNA3 5 0.60 4.59 2.45 100.00
27 INT203813 Negative_regulation of Lna1 1 0.17 1.73 0.42 100.00
28 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 100.00
29 INT121847 Negative_regulation of BPIFA4P 7 0.28 2.46 1.47 100.00
30 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 100.00
31 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87 100.00
32 INT73434 Negative_regulation of Nppa 8 0.35 3.86 4.31 100.00
33 INT144755 Negative_regulation of INSR 5 0.41 2.09 0.36 100.00
34 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 100.00
35 INT178183 Binding of Cd8a 16 0.32 7.8 0.85 100.00
36 INT16180 Regulation of DSPP 6 0.53 4.63 0.28 100.00
37 INT31407 Negative_regulation of HCA1 4 0.38 3.07 1.34 100.00
38 INT200748 Negative_regulation of Naq1 1 0.32 0.17 0 100.00
39 INT158663 Negative_regulation of Gene_expression of Sgpl1 3 0.11 0.91 2.17 100.00
40 INT282119 Negative_regulation of Negative_regulation of Plec 1 0.20 0.45 0 100.00
41 INT229681 Negative_regulation of Plec 2 0.39 1.71 0.3 100.00
42 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 100.00
43 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 100.00
44 INT146355 Negative_regulation of Aes 15 0.51 7.83 4.25 100.00
45 INT37216 Binding of SMN1 11 0.36 6.66 1.86 100.00
46 INT23951 Negative_regulation of Spn 4 0.15 2.17 1.12 100.00
47 INT201307 Negative_regulation of Vcan 4 0.41 1.71 0.43 100.00
48 INT242028 Negative_regulation of Negative_regulation of CRP 3 0.43 2.39 0.24 100.00
49 INT209345 Negative_regulation of AGTR2 5 0.17 4.83 0.2 100.00
50 INT214710 Negative_regulation of Bok 2 0.10 2.22 0.14 100.00
51 INT151522 Binding of NSD1 2 0.37 4.28 0.09 100.00
52 INT217690 Negative_regulation of Negative_regulation of BMI1 1 0.01 0.76 0 100.00
53 INT185407 Binding of PER1 13 0.42 9.32 2.6 99.98
54 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 99.96
55 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.96
56 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 99.96
57 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.96
58 INT220151 Negative_regulation of Lbm1 4 0.09 4.34 0.83 99.96
59 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 99.92
60 INT2254 Gene_expression of Gip 5 0.47 2.21 0.4 99.92
61 INT267922 Positive_regulation of Gene_expression of Gip 1 0.04 0.97 0.05 99.92
62 INT227698 Regulation of SSRP1 4 0.03 2.88 0.24 99.92
63 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 99.92
64 INT79140 Binding of HCC 36 0.31 46.96 1.87 99.92
65 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28 99.92
66 INT18156 Gene_expression of Fap 18 0.73 27.02 1.46 99.92
67 INT117080 Localization of Csrp1 6 0.42 7.23 3.09 99.92
68 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 99.90
69 INT104324 Negative_regulation of Baat 4 0.38 9.79 0.42 99.90
70 INT10228 Positive_regulation of PCS 49 0.67 28.72 7 99.90
71 INT90727 Negative_regulation of Gene_expression of FosB 4 0.54 0.5 3.37 99.90
72 INT39788 Positive_regulation of Scort1 3 0.17 1.01 3.47 99.90
73 INT39789 Positive_regulation of Positive_regulation of PCS 2 0.32 3.63 2.04 99.90
74 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 99.88
75 INT158668 Positive_regulation of Gene_expression of Sgpl1 1 0.05 1.15 5.09 99.88
76 INT158664 Gene_expression of Sgpl1 5 0.20 1.8 4.47 99.88
77 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14 99.84
78 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 99.84
79 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 99.84
80 INT35329 Positive_regulation of KRTAP19-9P 15 0.59 12.55 2.98 99.84
81 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 99.84
82 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.82
83 INT332612 Protein_catabolism of Glp1r 1 0.18 3.56 0.38 99.82
84 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.80
85 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 99.80
86 INT39518 Negative_regulation of HBN1 66 0.09 37.54 2.58 99.80
87 INT22454 Regulation of Crp 213 0.62 160.67 49.24 99.78
88 INT149369 Negative_regulation of Regulation of Crp 3 0.40 3.41 0.4 99.78
89 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.76
90 INT70970 Binding of COPD 144 0.42 180.34 18.29 99.76
91 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 99.76
92 INT186709 Regulation of HCA1 5 0.39 1.91 0.21 99.76
93 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58 99.76
94 INT26280 Negative_regulation of Positive_regulation of Oxt 13 0.52 3.05 5.11 99.74
95 INT141781 Positive_regulation of Negative_regulation of LEP 1 0.46 0.37 0.29 99.74
96 INT69486 Negative_regulation of Bcl2a1c 34 0.10 19.03 0.6 99.72
97 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83 99.72
98 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53 99.72
99 INT183066 Positive_regulation of Transcription of INS 8 0.49 5.31 0.34 99.72
100 INT183046 Transcription of INS 25 0.70 11.14 1.13 99.72
101 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 99.72
102 INT5710 Negative_regulation of Localization of Lhb 146 0.57 20.51 58.33 99.72
103 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14 99.72
104 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 99.70
105 INT7653 Regulation of Gs 3 0.21 1.87 0.87 99.70
106 INT36176 Negative_regulation of Gs 4 0.18 0.96 0.31 99.70
107 INT109133 Gene_expression of VCAN 52 0.75 53.11 0.84 99.68
108 INT53813 Positive_regulation of Cel 20 0.58 19.39 3.05 99.68
109 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.66
110 INT21527 Gene_expression of FosB 47 0.78 11.2 34.39 99.66
111 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 99.66
112 INT22339 Positive_regulation of Negative_regulation of Crh 5 0.67 1.36 2.59 99.66
113 INT17391 Gene_expression of GNAI1 11 0.75 5.26 4.7 99.62
114 INT332626 Protein_catabolism of Gip 1 0.27 0.49 0.04 99.62
115 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.60
116 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07 99.60
117 INT230448 Negative_regulation of MOGS 4 0.41 2.64 0.22 99.60
118 INT12054 Negative_regulation of MIA3 32 0.45 23.2 6.18 99.60
119 INT2038 Localization of Esr1 104 0.79 40.12 13.27 99.60
120 INT260174 Gene_expression of Rpe65 29 0.78 4.2 0.19 99.60
121 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 99.58
122 INT217685 Negative_regulation of BMI1 7 0.18 6.01 0.82 99.58
123 INT53067 Gene_expression of Pes1 1 0.53 1.54 0.67 99.58
124 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 99.56
125 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.56
126 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.54
127 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 99.54
128 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.52
129 INT200373 Binding of Omd 7 0.34 7.03 0.34 99.52
130 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 99.52
131 INT220472 Gene_expression of BAG6 1 0.11 13.93 0.12 99.50
132 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 99.48
133 INT185153 Negative_regulation of Retn 1 0.17 2.99 0.4 99.48
134 INT18773 Localization of ALB 117 0.80 69.18 13.8 99.46
135 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.44
136 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51 99.44
137 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35 99.42
138 INT3206 Positive_regulation of Got1 39 0.69 19.36 17.02 99.40
139 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24 99.40
140 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 99.38
141 INT36173 Positive_regulation of Gs 17 0.43 7.48 8.19 99.34
142 INT251 Regulation of INS 398 0.62 232.47 55.04 99.32
143 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9 99.32
144 INT185188 Gene_expression of Pif 1 0.77 23.21 2.95 99.30
145 INT101653 Negative_regulation of SAA1 7 0.39 7 1.33 99.30
146 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81 99.30
147 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 99.28
148 INT109411 Gene_expression of SAT1 61 0.77 67.99 3.08 99.28
149 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.24
150 INT44979 Positive_regulation of Pnp 11 0.59 5.61 2.41 99.24
151 INT296969 Gene_expression of NRIP1 1 0.78 26.23 0.38 99.24
152 INT296997 Positive_regulation of Gene_expression of NRIP1 1 0.70 5.77 0 99.24
153 INT116500 Binding of OMP 2 0.36 1.46 0.16 99.24
154 INT160258 Negative_regulation of Myo5a 3 0.35 3.96 0.09 99.24
155 INT75908 Regulation of LEP 77 0.60 60.16 15.19 99.22
156 INT28060 Positive_regulation of Hdlcl1 48 0.66 37.31 3.79 99.22
157 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47 99.22
158 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 99.20
159 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.20
160 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 99.20
161 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 99.20
162 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15 99.20
163 INT204366 Positive_regulation of Gene_expression of PPARGC1A 1 0.67 1.44 0 99.20
164 INT192765 Negative_regulation of Gene_expression of SAA1 1 0.34 4.55 0.54 99.16
165 INT345962 Positive_regulation of Ahi1 1 0.10 4.11 0 99.16
166 INT246675 Negative_regulation of Glp1r 5 0.55 6.01 0.41 99.16
167 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 99.12
168 INT65356 Localization of LEP 46 0.79 41.17 5.43 99.08
169 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 99.08
170 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 99.08
171 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2 99.08
172 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41 99.08
173 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.08
174 INT91338 Binding of Lep 31 0.48 26.86 5.39 99.08
175 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 99.08
176 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 99.08
177 INT85831 Positive_regulation of CA9 5 0.60 8.29 1.02 99.08
178 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 99.08
179 INT116501 Binding of ANC 4 0.36 1.8 0.18 99.08
180 INT224447 Gene_expression of FBXO2 7 0.75 7.33 1.31 99.06
181 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 99.04
182 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 99.04
183 INT208648 Positive_regulation of NCBP2 1 0.10 1.39 0.05 99.04
184 INT280030 Localization of Dpp4 2 0.28 2.03 0.27 99.02
185 INT28923 Negative_regulation of Ldha 8 0.58 4.94 3.11 98.98
186 INT39469 Negative_regulation of Alb 21 0.41 13.33 2.68 98.98
187 INT282121 Negative_regulation of Gene_expression of Ldha 1 0.09 0.52 0 98.98
188 INT5113 Binding of MROS 4 0.31 2.52 0.17 98.96
189 INT85829 Gene_expression of CA9 14 0.68 12.59 1.4 98.96
190 INT11346 Binding of Mtx1 39 0.41 24.88 21.21 98.96
191 INT85830 Positive_regulation of Gene_expression of CA9 4 0.41 5.47 1.02 98.96
192 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24 98.92
193 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 98.92
194 INT93009 Regulation of HBN1 24 0.17 17.6 2.03 98.92
195 INT35251 Regulation of Ghrl 21 0.60 8.26 2.6 98.92
196 INT128054 Gene_expression of Per1 15 0.61 2.12 11.84 98.88
197 INT345953 Negative_regulation of Ahi1 1 0.08 4.67 0 98.88
198 INT5711 Positive_regulation of Localization of Lhb 90 0.70 10.92 36.76 98.88
199 INT39350 Positive_regulation of Ighg2a 2 0.35 2.39 0.37 98.88
200 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 98.84
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