D:Wrinkles

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Disease Term
Synonyms Age Related Cutaneous Changes, AGE RELATED DERMAL CHANGES, ANTI WRINKES, Anti Wrinkle, Anti Wrinkling, Cutaneous Manifestations Of Age, Dermal Manifestations Of Age, PHOTO AGING, Photo Damage, PHOTOAGING, Photodamage
Documents 239
Hot Single Events 101
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Wrinkles. They are ordered first by their relevance to Wrinkles and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT274715 TBL1XR1 Positive_regulation of TIMP1 1 0.00 0.26 0.04 95.92
2 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08 94.24
3 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04 94.24
4 INT350909 Binding of Pcsk4 and Twist1 1 0.02 1.91 0.08 93.76
5 INT188594 Binding of Mthfd1 and Radil 1 0.01 0.25 0.12 83.68
6 INT336425 MGAT1 Positive_regulation of Gene_expression of COL5A2 1 0.00 0.4 0.08 82.40
7 INT274716 TBL1XR1 Positive_regulation of Gene_expression of MMP1 1 0.02 0.45 0 54.40
8 INT105240 POMC Positive_regulation of Gene_expression of CXCL10 1 0.07 1.18 1.16 54.28
9 INT280167 Twist1 Positive_regulation of MAPK8 1 0.29 0.94 0 45.60
10 INT280162 Twist1 Negative_regulation of Binding of MAPK8 and Twist1 1 0.18 0.78 0 34.64
11 INT280166 Binding of MAPK8 and Twist1 1 0.19 0.78 0 34.64
12 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
13 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
14 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
15 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
16 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99 5.00
17 INT244396 Binding of Cl and Slc12a2 1 0.03 0.88 0.76 5.00
18 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
19 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57 5.00
20 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
21 INT155009 IL23A Positive_regulation of Gene_expression of IL17A 2 0.17 0.62 0.39 5.00
22 INT325312 IL20 Positive_regulation of Phosphorylation of STAT3 1 0.13 0.58 0.24 5.00
23 INT325316 IL22 Positive_regulation of Phosphorylation of STAT3 1 0.19 0.58 0.24 5.00
24 INT325315 Binding of STAT3 and TH1L 1 0.16 0.6 0.23 5.00
25 INT325313 IL23A Positive_regulation of Gene_expression of IL22 1 0.20 0.48 0.23 5.00
26 INT325314 Binding of IL12A and STAT3 1 0.19 0.6 0.22 5.00
27 INT325317 Binding of IL12A and TH1L 1 0.18 0.59 0.22 5.00
28 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19 5.00
29 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 5.00
30 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 5.00
31 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 5.00
32 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15 5.00
33 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12 5.00
34 INT275462 Negative_regulation of JUN Positive_regulation of Gene_expression of MMP9 1 0.04 0.27 0.12 5.00
35 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 5.00
36 INT206042 Negative_regulation of FDPS Negative_regulation of Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
37 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09 5.00
38 INT206075 Negative_regulation of FDPS Negative_regulation of Binding of GGPS1 1 0.01 0 0.09 5.00
39 INT206078 Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
40 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08 5.00
41 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07 5.00
42 INT244130 Binding of CASP1 and RNGTT 1 0.07 0.24 0.07 5.00
43 INT244131 Binding of RNGTT and NLRP1 1 0.11 0.24 0.07 5.00
44 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07 5.00
45 INT302985 HIVEP1 Positive_regulation of Positive_regulation of AHR 1 0.06 0.5 0.06 5.00
46 INT302984 MBP Positive_regulation of AHR 1 0.31 0.3 0.06 5.00
47 INT275463 ZNF69 Negative_regulation of MMP2 1 0.01 0 0.05 5.00
48 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05 5.00
49 INT275464 ZNF69 Negative_regulation of Gene_expression of MMP2 1 0.01 0 0.05 5.00
50 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04 5.00
51 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04 5.00
52 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04 5.00
53 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04 5.00
54 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04 5.00
55 INT244129 Binding of RNGTT and NOD1 1 0.11 0 0.04 5.00
56 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03 5.00
57 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03 5.00
58 INT244132 DDB1 Regulation of Transcription of NOD1 1 0.01 0.09 0.03 5.00
59 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03 5.00
60 INT346331 Binding of Epo and Egf 1 0.19 0.1 0.03 5.00
61 INT353551 Pck1 Regulation of SLC17A5 1 0.00 0 0 5.00
62 INT353549 Pck1 Regulation of Gene_expression of Gpt 1 0.00 0 0 5.00
63 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0 5.00
64 INT206058 EGFR Negative_regulation of Gene_expression of IL6 1 0.07 0.62 0 5.00
65 INT280164 Twist1 Negative_regulation of Mod2 1 0.06 1.76 0 5.00
66 INT206079 ANG Regulation of KRT20 1 0.00 0.54 0 5.00
67 INT206069 ANG Positive_regulation of Gene_expression of IL6 1 0.05 0.51 0 5.00
68 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0 5.00
69 INT206178 Foxm1 Positive_regulation of Protein_catabolism of Olr1 1 0.00 0.47 0 5.00
70 INT273136 Binding of CHED1 and VSX1 1 0.15 0.12 0 5.00
71 INT350906 Twist1 Positive_regulation of Gene_expression of Cd4 1 0.10 1.49 0 5.00
72 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0 5.00
73 INT206060 FDPS Positive_regulation of AKT1 1 0.00 0.4 0 5.00
74 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0 5.00
75 INT206082 IL6 Positive_regulation of Gene_expression of CCL2 1 0.07 0.3 0 5.00
76 INT322931 Binding of MOCS1 and Litaf 1 0.00 0.82 0 5.00
77 INT206180 Foxm1 Positive_regulation of Transcription of Olr1 1 0.00 0.48 0 5.00
78 INT353550 Pck1 Regulation of Gpt 1 0.00 0 0 5.00
79 INT350907 Twist1 Positive_regulation of Gene_expression of Cd7 1 0.05 1.49 0 5.00
80 INT206077 RAC1 Positive_regulation of Phosphorylation of STAT3 1 0.07 0.35 0 5.00
81 INT171478 Binding of DBP and RPL6 1 0.00 0.26 0 5.00
82 INT206181 FDPS Positive_regulation of ras 1 0.00 0.4 0 5.00
83 INT280163 Twist1 Positive_regulation of Mod2 1 0.07 1.67 0 5.00
84 INT206084 EGF Negative_regulation of Gene_expression of IL6 1 0.05 0.61 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Wrinkles. They are ordered first by their pain relevance and then by number of times they were reported in Wrinkles. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT172855 Binding of Bcl2 37 0.32 23.41 1.09 100.00
2 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 100.00
3 INT66862 Regulation of Esr2 3 0.24 1.56 1.01 99.80
4 INT153918 Binding of Esr2 3 0.33 2.56 1.7 99.80
5 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 99.30
6 INT158123 Negative_regulation of Gene_expression of COL5A2 19 0.46 15.27 2.23 99.30
7 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.28
8 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.28
9 INT49020 Negative_regulation of TYR 11 0.58 1.97 2.68 99.16
10 INT146028 Negative_regulation of Positive_regulation of TYR 1 0.43 0.69 0.26 99.16
11 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 99.04
12 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 98.96
13 INT3364 Binding of SGCG 87 0.47 31.93 17.24 98.80
14 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 98.64
15 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 98.64
16 INT49025 Positive_regulation of TYR 14 0.69 7.15 5.84 98.64
17 INT103272 Positive_regulation of Gene_expression of Dio1 4 0.26 1.66 1.34 98.64
18 INT21737 Binding of MC1R 129 0.48 45.45 56.54 98.28
19 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 98.24
20 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 98.12
21 INT124293 Negative_regulation of PDHA1 4 0.28 0.66 0.07 98.12
22 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 98.12
23 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 98.12
24 INT50618 Gene_expression of Dio1 48 0.74 17.37 15.91 98.12
25 INT97264 Binding of Mc1r 9 0.36 4.27 4.53 98.04
26 INT274185 Localization of ELN 4 0.73 1.25 0.1 97.44
27 INT341107 Negative_regulation of Localization of ELN 1 0.41 0.66 0.1 97.44
28 INT334553 Localization of HAS1 1 0.11 1.07 0.09 97.36
29 INT313892 Localization of CADPS 1 0.48 2.37 0.2 97.16
30 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 96.64
31 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54 96.24
32 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 96.20
33 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 95.52
34 INT334551 Regulation of HAS1 1 0.04 0.46 0.04 95.48
35 INT334554 Positive_regulation of HAS1 1 0.07 0.46 0.04 95.48
36 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92 95.24
37 INT20981 Binding of HRAS 42 0.48 24.49 4.23 95.16
38 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 95.08
39 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 95.08
40 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 95.04
41 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 94.12
42 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 93.56
43 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83 93.36
44 INT108556 Negative_regulation of BCL2L10 8 0.32 7.77 1.49 92.88
45 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08 92.08
46 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 91.84
47 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 91.68
48 INT92191 Positive_regulation of Positive_regulation of Eln 1 0.15 0.54 0.1 91.56
49 INT336458 Positive_regulation of MGAT1 1 0.05 2.92 0.4 91.52
50 INT70987 Binding of RAC1 14 0.37 12.14 2.13 91.20
51 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 90.96
52 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 90.68
53 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35 90.68
54 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 90.32
55 INT99608 Transcription of MMP9 18 0.65 9.67 4.11 90.00
56 INT187022 Positive_regulation of Transcription of MMP9 3 0.45 3.27 0.34 90.00
57 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31 89.80
58 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57 89.64
59 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75 89.36
60 INT120511 Positive_regulation of Gene_expression of Cat 26 0.69 19.82 5.2 89.36
61 INT626 Localization of CALCA 289 0.81 125.39 221.15 89.00
62 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 89.00
63 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45 89.00
64 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4 89.00
65 INT307326 Negative_regulation of Gene_expression of CALR 3 0.25 1.78 0 89.00
66 INT112551 Protein_catabolism of Rac1 2 0.66 0.29 0.3 88.96
67 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 88.76
68 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 88.76
69 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 88.20
70 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14 88.12
71 INT37590 Regulation of COL7A1 15 0.54 9.4 3.12 88.04
72 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 88.00
73 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 88.00
74 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 88.00
75 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 87.88
76 INT82928 Positive_regulation of Eln 7 0.69 3.54 0.77 87.20
77 INT123757 Positive_regulation of Snap25 3 0.47 0.41 0.77 87.12
78 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 86.96
79 INT241960 Negative_regulation of Rhbdl1 2 0.41 0.57 0.78 86.64
80 INT81500 Protein_catabolism of Snap25 10 0.66 1.12 2.12 86.44
81 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08 85.44
82 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 84.80
83 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 84.32
84 INT120510 Gene_expression of Lrdg1 1 0.16 1.43 0.28 83.68
85 INT77788 Regulation of Tnfrsf1a 14 0.57 11.24 3.53 83.20
86 INT313563 Regulation of KIAA1524 1 0.09 0.3 0 83.20
87 INT313562 Regulation of CENPV 1 0.03 0.3 0 83.20
88 INT313557 Regulation of Ppp1r9a 1 0.10 0.3 0 83.20
89 INT139664 Gene_expression of CCL18 83 0.76 37.05 21.95 83.16
90 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 83.16
91 INT12717 Binding of Pck1 85 0.47 12.49 54.81 83.08
92 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 82.32
93 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 82.32
94 INT55736 Transcription of MMP2 11 0.68 5.78 2.28 82.32
95 INT275479 Negative_regulation of Transcription of MMP2 2 0.25 0.43 0.16 82.32
96 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 81.24
97 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 81.12
98 INT95641 Regulation of Fbn1 3 0.45 3.67 0.91 81.04
99 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41 81.00
100 INT86119 Regulation of Cftr 13 0.45 14.08 5.75 80.84
101 INT273158 Binding of COL8A2 1 0.33 2.02 0.22 80.36
102 INT6852 Localization of TNF 883 0.81 705.95 270.84 79.48
103 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39 79.08
104 INT120513 Negative_regulation of Gene_expression of Lrdg1 1 0.12 0.73 0.15 79.08
105 INT151835 Positive_regulation of UBE4B 1 0.48 0.68 0.08 78.88
106 INT127768 Gene_expression of Sec22b 5 0.13 1.93 1.33 78.64
107 INT120512 Positive_regulation of Gene_expression of Lrdg1 1 0.12 0.73 0.15 78.52
108 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 77.96
109 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39 77.96
110 INT246311 Protein_catabolism of Snap25 6 0.66 1.15 0.89 77.68
111 INT246317 Positive_regulation of Snap25 10 0.50 0.74 0.67 77.68
112 INT246318 Negative_regulation of Protein_catabolism of Snap25 2 0.19 0.34 0 77.68
113 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 77.16
114 INT59964 Localization of Pcsk4 3 0.59 2.25 0.23 77.12
115 INT10873 Localization of Twist1 21 0.74 10.43 1.37 76.92
116 INT108628 Regulation of MMP2 27 0.60 14.85 6.06 76.56
117 INT350904 Localization of TSPYL2 1 0.03 1.04 0.04 76.00
118 INT117024 Negative_regulation of Localization of Acot1 6 0.41 1.56 1.7 75.36
119 INT148426 Gene_expression of Snap25 12 0.68 1.72 1.63 75.12
120 INT95640 Transcription of Fbn1 1 0.53 0.21 0.08 75.00
121 INT47425 Localization of Chrna7 11 0.81 6.7 1.86 75.00
122 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 74.96
123 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 74.96
124 INT45437 Localization of Acot1 84 0.79 17.37 22.18 74.36
125 INT179884 Gene_expression of SOCS3 10 0.67 16.57 1.14 73.88
126 INT96579 Negative_regulation of Negative_regulation of MMP9 5 0.40 4.55 1.04 73.56
127 INT99653 Gene_expression of CACNA1I 2 0.29 2.22 1.34 73.12
128 INT34544 Gene_expression of L1cam 43 0.77 5.3 8.89 72.96
129 INT197364 Gene_expression of MCAT 18 0.16 24.11 4.27 72.80
130 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 72.36
131 INT40713 Negative_regulation of EPX 7 0.37 2.21 1.73 72.36
132 INT135527 Negative_regulation of Gene_expression of Cd4 17 0.43 6.72 1.09 72.36
133 INT313556 Negative_regulation of Ppp1r9a 1 0.09 0.98 0 71.96
134 INT313560 Negative_regulation of KIAA1524 1 0.07 0.59 0 71.96
135 INT111488 Gene_expression of HAS1 56 0.77 32.6 15.29 71.80
136 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 71.76
137 INT39877 Positive_regulation of EPX 13 0.69 6.01 1.21 71.68
138 INT350902 Negative_regulation of Cd7 1 0.15 1.87 0 71.48
139 INT96581 Negative_regulation of Negative_regulation of MMP2 4 0.57 3.1 1.04 70.96
140 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69 70.72
141 INT129961 Regulation of Gene_expression of MMP1 15 0.46 4.88 2.51 70.72
142 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86 70.16
143 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35 70.00
144 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 69.76
145 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84 69.76
146 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 68.80
147 INT65053 Positive_regulation of Binding of Nfkb1 11 0.65 3.78 2.84 67.80
148 INT109021 Negative_regulation of Binding of Nfkb1 7 0.39 4.13 1.42 67.32
149 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02 66.92
150 INT84641 Positive_regulation of MAP2K4 5 0.13 3.41 0.77 66.80
151 INT280156 Positive_regulation of Gene_expression of MAP2K4 1 0.03 1.02 0 66.80
152 INT280155 Gene_expression of MAP2K4 2 0.30 1.56 0 66.80
153 INT1643 Regulation of CSH1 10 0.26 2.45 2.53 66.72
154 INT146479 Regulation of Gene_expression of HAS1 6 0.45 1.85 1.13 66.72
155 INT47483 Regulation of Gene_expression of CSH1 4 0.34 0.32 0.07 66.72
156 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 66.32
157 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36 66.32
158 INT132103 Positive_regulation of Gene_expression of MAPK8 26 0.46 16.54 3.94 66.32
159 INT350900 Protein_catabolism of Twist1 1 0.22 0.78 0.05 65.20
160 INT45275 Gene_expression of CSH1 39 0.62 9.39 5.85 64.48
161 INT14448 Localization of COL5A2 34 0.67 17.35 2.85 64.24
162 INT334552 Negative_regulation of Localization of HAS1 1 0.06 0.13 0 64.24
163 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53 62.84
164 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 62.68
165 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 61.08
166 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47 60.24
167 INT110252 Positive_regulation of Gene_expression of RELA 29 0.49 6.36 1.31 60.24
168 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 60.24
169 INT195145 Positive_regulation of Gene_expression of CA2 25 0.37 7.2 6.59 60.24
170 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41 60.24
171 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 60.12
172 INT66213 Localization of RELA 63 0.78 14.71 8.77 59.92
173 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43 59.92
174 INT108875 Positive_regulation of Localization of RELA 9 0.49 1.43 1.72 59.92
175 INT12082 Localization of IL6 365 0.81 241.78 105.78 59.60
176 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 59.60
177 INT95944 Binding of Fgf12 11 0.28 8.98 2.53 59.36
178 INT65834 Negative_regulation of ATP2A2 4 0.07 2.39 0.21 59.20
179 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 59.20
180 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 59.20
181 INT219579 Negative_regulation of Gene_expression of Twist1 12 0.43 9.07 1.36 59.20
182 INT70323 Negative_regulation of Gene_expression of CA2 13 0.41 6.55 0.97 59.20
183 INT5847 Transcription of FOS 31 0.69 11.11 6.41 56.08
184 INT88179 Negative_regulation of Transcription of FOS 3 0.41 0.96 0.78 56.08
185 INT39733 Localization of NFKB1 59 0.79 22.76 13.99 55.16
186 INT66209 Negative_regulation of Localization of NFKB1 23 0.58 8.2 5.31 55.16
187 INT66211 Positive_regulation of Localization of NFKB1 20 0.68 8.18 5.01 55.16
188 INT27627 Binding of Rac1 41 0.41 22.88 13.68 54.92
189 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 54.88
190 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97 53.72
191 INT756 Gene_expression of C3 138 0.75 100.6 19.2 52.40
192 INT273145 Negative_regulation of COL8A2 1 0.40 0.83 0.06 50.44
193 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 50.00
194 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75 50.00
195 INT121967 Regulation of RAC1 9 0.45 6.14 3.41 50.00
196 INT85885 Positive_regulation of SNAP25 8 0.69 2.74 2.84 50.00
197 INT115303 Localization of SNAP25 8 0.73 1.43 1.82 50.00
198 INT175904 Localization of RAC1 7 0.41 5.05 0.86 50.00
199 INT211361 Regulation of RENBP 5 0.08 2.8 0.38 50.00
200 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 49.68
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