Evaluation:3

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These are evaluation pages designed to aid in the manual curation process.

These are ints 1000-1500 ordered by relevance to pain.

Molecular Interactions

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT237286 Dlat Regulation of Prep 1 0.01 0 1.57
2 INT12327 Igh-Dex Positive_regulation of Plec 1 0.03 0.73 1.57
3 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
4 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
5 INT26985 Cpe Negative_regulation of Localization of Ins1 1 0.02 0 1.57
6 INT81710 POMC Regulation of Gene_expression of FCGR3B 1 0.50 0.34 1.57
7 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
8 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
9 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
10 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57
11 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57
12 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
13 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
14 INT81712 POMC Regulation of FCGR3B 1 0.16 0.34 1.56
15 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
16 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
17 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
18 INT130839 Gfap Positive_regulation of S100B 1 0.51 1.9 1.56
19 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
20 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
21 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
22 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
23 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
24 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
25 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
26 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55
27 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
28 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
29 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
30 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
31 INT127253 Binding of Npb and Npbwr1 2 0.29 0.61 1.55
32 INT6768 Oprl1 Regulation of Localization of Prl 2 0.12 0 1.55
33 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
34 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
35 INT111892 Ptger2 Regulation of Ptger1 1 0.08 2.09 1.55
36 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
37 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55
38 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
39 INT264950 Binding of FPR1 and BOC 1 0.11 0.67 1.55
40 INT118157 Binding of Prkca and Prkcz Positive_regulation of Binding of Prkca Prkcz 1 0.02 0.58 1.55
41 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
42 INT81721 POMC Regulation of ITGAM 1 0.39 0.34 1.55
43 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
44 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
45 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
46 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
47 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
48 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
49 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
50 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
51 INT54844 Negative_regulation of Penk Positive_regulation of Vip 1 0.26 0 1.54
52 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
53 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
54 INT118159 Binding of Prkca and Prkcz Positive_regulation of Prkcz 1 0.02 0.58 1.54
55 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54
56 INT33815 Vta1 Negative_regulation of Penk 1 0.25 0 1.54
57 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
58 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
59 INT7797 Akr1d1 Regulation of Sst 1 0.02 0 1.54
60 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54
61 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
62 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
63 INT118160 Binding of Prkca and Prkcz Positive_regulation of Prkca 1 0.11 0.58 1.54
64 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
65 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
66 INT32152 POMC Positive_regulation of Gene_expression of IFNA1 2 0.67 0 1.53
67 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
68 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
69 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
70 INT274943 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Tac2 1 0.04 0.49 1.53
71 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
72 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
73 INT158778 Ptges3l1 Regulation of Ephb1 1 0.06 0.09 1.53
74 INT40887 Penk Regulation of Th 1 0.04 0 1.53
75 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
76 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
77 INT245347 Binding of Penk and Vta1 1 0.05 0.14 1.53
78 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
79 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
80 INT145072 ASIP Negative_regulation of MC1R 1 0.29 0 1.52
81 INT23546 Negative_regulation of CNDP2 Negative_regulation of POMC Positive_regulation of POMC 1 0.04 0 1.52
82 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
83 INT182706 NPFF Regulation of Binding of TP53INP2 1 0.01 0.07 1.52
84 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
85 INT140016 Avp Positive_regulation of Gene_expression of Pdyn 1 0.21 0.85 1.52
86 INT23548 Negative_regulation of CNDP2 Negative_regulation of Localization of POMC 1 0.03 0 1.52
87 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
88 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
89 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
90 INT69709 NPL Positive_regulation of Localization of POMC 2 0.36 1.22 1.51
91 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
92 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 0.08 0.22 1.51
93 INT317538 Binding of Neu3 and Mors1 1 0.00 0 1.51
94 INT63490 Negative_regulation of Dio1 Positive_regulation of Rtcd1 1 0.01 0.58 1.51
95 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
96 INT42001 Cck Regulation of Vip 1 0.28 0 1.51
97 INT192081 Igkv11-125 Positive_regulation of Cnr1 1 0.10 0.23 1.51
98 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
99 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
100 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
101 INT63489 Dio1 Positive_regulation of Rtcd1 1 0.01 0.58 1.51
102 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
103 INT62481 Penk Negative_regulation of Slc6a7 2 0.60 0 1.5
104 INT30463 Binding of PDYN and Penk 2 0.01 0 1.5
105 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
106 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
107 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
108 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
109 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
110 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
111 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5
112 INT45502 TNS1 Positive_regulation of VIP 1 0.47 0.52 1.5
113 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
114 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5
115 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
116 INT48101 RT1-DMb Positive_regulation of Penk 1 0.10 0 1.5
117 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
118 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
119 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5
120 INT334347 GRP Positive_regulation of Localization of Gabrg1 1 0.19 0 1.5
121 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
122 INT69788 Binding of Gpr1 and Pnoc 2 0.09 0 1.49
123 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
124 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
125 INT174450 Positive_regulation of Binding of Cxcr3 and Smcp 1 0.18 2.83 1.49
126 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
127 INT322812 Binding of SLC12A1 and MOCOS 1 0.00 1.69 1.49
128 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49
129 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
130 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
131 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
132 INT93782 Racgap1 Positive_regulation of Rgs9 1 0.55 0.07 1.49
133 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
134 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
135 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
136 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49
137 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49
138 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
139 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49
140 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
141 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
142 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
143 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
144 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
145 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48
146 INT44505 Mt1a Positive_regulation of Mt1a Positive_regulation of Prl 1 0.19 0 1.48
147 INT14375 Gal Positive_regulation of Localization of Prl 1 0.77 0 1.48
148 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48
149 INT211744 Binding of Gopc and Mors1 1 0.10 0.2 1.48
150 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
151 INT155497 Oprk1 Negative_regulation of Tenc1 1 0.08 0.34 1.48
152 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
153 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48
154 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
155 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
156 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
157 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
158 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
159 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
160 INT140332 RPL7AP5 Negative_regulation of Ltp 1 0.00 0.64 1.47
161 INT116094 Binding of TACR1 and TFF2 1 0.06 0 1.47
162 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47
163 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
164 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47
165 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
166 INT165450 Gal Regulation of Ceacam3 1 0.41 0.06 1.47
167 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
168 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
169 INT27932 Binding of CCK and NCOR2 1 0.01 0.91 1.47
170 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
171 INT40209 TNS3 Regulation of POMC 1 0.16 0.27 1.47
172 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
173 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
174 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
175 INT136843 Binding of Camk2a and Nrgn 1 0.47 0 1.47
176 INT131564 Binding of Npw and Npbwr1 3 0.41 0.35 1.46
177 INT144452 Binding of GPM6A and GPM6B 1 0.28 0 1.46
178 INT39109 Binding of INSRR and PDYN 1 0.15 0.45 1.46
179 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
180 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
181 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
182 INT276688 Positive_regulation of Prkcg Positive_regulation of Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.46
183 INT118812 Cck Positive_regulation of Rvm 1 0.21 0.65 1.46
184 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
185 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
186 INT123899 Binding of CYP3A4 and UGT2B7 1 0.52 0 1.46
187 INT141676 OPRM1 Positive_regulation of Ltp 1 0.04 0 1.46
188 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
189 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46
190 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
191 INT161871 Mors1 Positive_regulation of GRIN1 1 0.01 0.12 1.46
192 INT104975 MITF Regulation of Transcription of PRSS1 1 0.68 0.35 1.46
193 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
194 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
195 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
196 INT276675 Binding of Nkx1-1 and Nav1 1 0.09 0.21 1.46
197 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 0.04 0 1.46
198 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
199 INT12691 SST Negative_regulation of Localization of POMC 3 0.24 1.24 1.45
200 INT1314 Pomc Regulation of Localization of Gnrhr 2 0.16 0.14 1.45
201 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
202 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
203 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
204 INT144454 Binding of DMPK and GPM6A 1 0.00 0 1.45
205 INT6976 Helt Regulation of Gene_expression of St8sia1 1 0.00 0.07 1.45
206 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
207 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
208 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
209 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
210 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
211 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
212 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
213 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
214 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
215 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
216 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
217 INT351246 Binding of OPN1LW and NNT 1 0.03 0.53 1.45
218 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
219 INT29127 Npy Positive_regulation of LH 1 0.47 0 1.45
220 INT161860 OPRM1 Positive_regulation of OPRM1 Positive_regulation of GRIN1 1 0.56 0.12 1.45
221 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
222 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
223 INT150392 Binding of MEFV and PSTPIP1 2 0.51 10.49 1.44
224 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
225 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44
226 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
227 INT111760 Dio1 Positive_regulation of Binding of Cpe 1 0.04 0.34 1.44
228 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
229 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
230 INT19013 Ghsr Negative_regulation of Localization of Sst 1 0.15 0 1.44
231 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
232 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
233 INT19012 Ghsr Negative_regulation of Localization of Sstr1 1 0.10 0 1.44
234 INT136346 Binding of Aap and Ads1 1 0.09 2.95 1.44
235 INT318491 IRF6 Positive_regulation of FPR2 1 0.10 6.14 1.44
236 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
237 INT356233 Slc32a1 Positive_regulation of Gabrg1 1 0.17 1.6 1.44
238 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
239 INT158282 Binding of Penk and Csf2 1 0.33 0.87 1.44
240 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
241 INT30872 Abat Positive_regulation of Localization of Gast 1 0.26 0 1.43
242 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
243 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
244 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
245 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
246 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
247 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 0.01 0.33 1.43
248 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
249 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
250 INT128915 PENK Regulation of Gene_expression of OPRM1 1 0.22 0.07 1.43
251 INT137958 Asprv1 Positive_regulation of Localization of Pdyn 1 0.21 0 1.43
252 INT158283 Binding of Penk and Accn4 1 0.07 0.87 1.43
253 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43
254 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
255 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
256 INT150069 Cnr1 Regulation of Cnr2 2 0.50 0.83 1.42
257 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42
258 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
259 INT10548 Nts Regulation of Localization of Abat 2 0.14 0 1.42
260 INT111756 Dio1 Positive_regulation of Cpe 1 0.04 0.34 1.42
261 INT31391 Binding of PRCP and Abpa 1 0.03 0.16 1.42
262 INT224404 Binding of GYPC and PYY 1 0.04 1.48 1.42
263 INT139768 Binding of TRPV1 and ICK 1 0.41 1.59 1.42
264 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
265 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
266 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
267 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
268 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
269 INT76770 Binding of HTR1E and Gs 1 0.00 0.87 1.42
270 INT139767 ICK Regulation of TRPV1 1 0.30 1.59 1.42
271 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
272 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
273 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
274 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
275 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
276 INT29554 Ebp Positive_regulation of LH 2 0.40 0.12 1.41
277 INT96796 ITIH4 Regulation of Gene_expression of OPRM1 2 0.20 0.89 1.41
278 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
279 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
280 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41
281 INT154114 PENK Positive_regulation of YY1 1 0.50 0.06 1.41
282 INT154111 POMC Positive_regulation of Localization of PENK 1 0.34 0.05 1.41
283 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41
284 INT41591 Binding of PDYN and FAIM3 1 0.00 0 1.41
285 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
286 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
287 INT128913 Binding of COMT and PENK 1 0.30 0.07 1.41
288 INT298458 Binding of Calcrl and Adarb1 1 0.00 0.23 1.41
289 INT154110 PENK Positive_regulation of Localization of POMC 1 0.34 0.05 1.41
290 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41
291 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
292 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
293 INT75370 Positive_regulation of Binding of Hrh1 and RGD735065 1 0.00 0.56 1.41
294 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41
295 INT189299 Atp6v1e1 Positive_regulation of Htr2a 1 0.01 1.01 1.41
296 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
297 INT92430 LOC681261 Positive_regulation of Ean2 1 0.01 1.52 1.41
298 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
299 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
300 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
301 INT75371 Binding of Hrh1 and RGD735065 1 0.00 0.55 1.4
302 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
303 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
304 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
305 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
306 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
307 INT148451 Gene_expression of Inhbe Positive_regulation of Pik3cd 1 0.04 1.35 1.4
308 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
309 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
310 INT140314 PCSK7 Positive_regulation of LDHA 1 0.07 1.6 1.4
311 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
312 INT93388 Rbm39 Positive_regulation of Positive_regulation of Pdyn 1 0.03 0.32 1.4
313 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
314 INT266811 Binding of HRH1 and HTR2C 1 0.23 2.06 1.4
315 INT154685 Syt17 Positive_regulation of Trpa1 1 0.32 0.71 1.4
316 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
317 INT299311 Binding of RPTOR and RICTOR 1 0.38 0.21 1.4
318 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 0.20 0.19 1.4
319 INT144123 Binding of P2rx6 and Trpv1 1 0.11 0 1.4
320 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
321 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4
322 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
323 INT79745 Gtf3a Positive_regulation of Positive_regulation of Sst 1 0.09 0 1.4
324 INT240730 Binding of CRYGD and MTRF1 4 0.03 4.18 1.39
325 INT161188 NMS Regulation of Gene_expression of Rvm 1 0.03 2 1.39
326 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
327 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
328 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
329 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
330 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
331 INT133937 Binding of OPRK1 and ARFGEF1 1 0.01 0 1.39
332 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
333 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
334 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
335 INT227152 Positive_regulation of Binding of Mop3 and Gpm6a 1 0.00 0 1.39
336 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 1 0.06 0.49 1.39
337 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
338 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
339 INT116827 Binding of UCHL1 and TRPV1 1 0.41 0.88 1.39
340 INT161189 CRX Regulation of Gene_expression of Rvm 1 0.00 2 1.39
341 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
342 INT134681 FSCN1 Positive_regulation of FSCN1 Positive_regulation of MAPK8 1 0.00 0.56 1.39
343 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
344 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
345 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
346 INT73377 Npy Regulation of Adarb1 2 0.03 0.15 1.38
347 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
348 INT27123 Binding of Pomc and Cck 2 0.31 0 1.38
349 INT2170 Penk Regulation of Localization of LH 2 0.44 0 1.38
350 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
351 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38
352 INT140021 Avp Positive_regulation of Pag1 1 0.03 0.85 1.38
353 INT29599 Binding of Cyp21a1 and Adarb1 1 0.01 0 1.38
354 INT140018 Avp Positive_regulation of Gene_expression of Pag1 1 0.04 0.85 1.38
355 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
356 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
357 INT190128 Positive_regulation of PTGER1 Negative_regulation of Gene_expression of CPOX 1 0.04 1.21 1.38
358 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
359 INT131949 ANTXR1 Positive_regulation of NAV1 1 0.03 0.23 1.38
360 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
361 INT140020 Avp Positive_regulation of Localization of Pag1 1 0.03 0.85 1.38
362 INT227151 Binding of Mop3 and Gpm6a 1 0.00 0 1.38
363 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
364 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
365 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 0.09 1.76 1.38
366 INT55837 Binding of HLA-B and PHB2 3 0.20 3.52 1.37
367 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37
368 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
369 INT87266 Negative_regulation of Binding of BMP8B and KRIT1 1 0.05 0.07 1.37
370 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37
371 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
372 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
373 INT212662 KCNA1 Regulation of Localization of Cort 1 0.00 1.36 1.37
374 INT276673 Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.37
375 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
376 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
377 INT60993 Ntf4 Negative_regulation of Positive_regulation of CRTAC1 1 0.00 0 1.37
378 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
379 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
380 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
381 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
382 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37
383 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
384 INT18589 Gast Regulation of Localization of Sst 1 0.61 0.15 1.37
385 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
386 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
387 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
388 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
389 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
390 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
391 INT66569 Pomc Positive_regulation of Atxn2l 1 0.03 0 1.36
392 INT117871 Sct Positive_regulation of Pes1 1 0.10 0 1.36
393 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
394 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
395 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
396 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
397 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
398 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
399 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
400 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
401 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
402 INT115272 Neu1 Positive_regulation of Coq10a 1 0.43 0.41 1.35
403 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
404 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
405 INT115271 Neu1 Positive_regulation of Coq10a 1 0.01 0.41 1.35
406 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
407 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
408 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
409 INT60992 Ngf Regulation of CRTAC1 1 0.00 0 1.35
410 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
411 INT15277 Binding of Tac1 and Gal 1 0.39 0.19 1.35
412 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
413 INT151382 St8sia1 Positive_regulation of Cck Regulation of St8sia1 1 0.04 0.22 1.35
414 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
415 INT75807 Gpm6a Positive_regulation of Localization of Penk 1 0.04 0 1.35
416 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
417 INT33988 TRH Regulation of Localization of IGKV1D-39 1 0.12 0.47 1.35
418 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
419 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
420 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
421 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
422 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
423 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
424 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
425 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
426 INT54490 Npepo Positive_regulation of Gene_expression of Pdyn 1 0.06 0 1.35
427 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 0.51 0 1.35
428 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
429 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
430 INT52568 HTR1D Regulation of Localization of Gh 2 0.20 0.16 1.34
431 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
432 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
433 INT140532 Gtf3a Positive_regulation of DYT10 1 0.12 1.83 1.34
434 INT352196 Igkv12-66 Negative_regulation of Gm10404 1 0.00 1.62 1.34
435 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
436 INT185330 Binding of Hrh1 and Tac1 1 0.00 0.1 1.34
437 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
438 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
439 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34
440 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
441 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
442 INT87812 Penk Regulation of Prl 1 0.16 0 1.34
443 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
444 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
445 INT19633 GNRH1 Regulation of Localization of CGA 4 0.44 0.82 1.33
446 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
447 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
448 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
449 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
450 INT145473 Mastl Positive_regulation of Dnahc8 1 0.07 0.06 1.33
451 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 0.20 0 1.33
452 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
453 INT143999 IK Regulation of Gene_expression of Penk 1 0.04 0 1.33
454 INT249565 Binding of Gabrg1 and Oprd1 1 0.00 0.1 1.33
455 INT68071 Binding of Tic1 and Rbm39 1 0.01 2.54 1.33
456 INT38453 Binding of Pomc and Penk 1 0.17 0 1.33
457 INT777 Prss12 Positive_regulation of Prl 1 0.19 0 1.33
458 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
459 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
460 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33
461 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
462 INT116102 Cck Positive_regulation of Negative_regulation of Pnoc 1 0.51 0.41 1.33
463 INT14827 Binding of Gabrd and Pag1 1 0.07 0.95 1.33
464 INT126831 Binding of Oprk1 and Rbm39 1 0.05 0.88 1.33
465 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
466 INT2641 Binding of Pomc and Lct 2 0.31 0.57 1.32
467 INT209409 Binding of CALM1 and NHS 2 0.27 0.58 1.32
468 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
469 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
470 INT91305 Binding of Npff and Npffr2 2 0.31 0.64 1.32
471 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
472 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
473 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
474 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
475 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
476 INT76508 Pnoc Regulation of Oprl1 1 0.47 0.25 1.32
477 INT71395 Ugt2a2 Regulation of Bcl2a1a 1 0.00 0.1 1.32
478 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
479 INT13756 Binding of Oprd1 and Scn4a 1 0.02 0 1.32
480 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 0.03 0.19 1.32
481 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
482 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
483 INT13755 Binding of Oprd1 and Ap2m1 1 0.20 0 1.32
484 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
485 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
486 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
487 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31
488 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
489 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
490 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
491 INT51200 Binding of OPRM1 and PENK 2 0.17 0.23 1.31
492 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
493 INT90221 Binding of CYP2D6 and Cyp1a2 1 0.03 0.09 1.31
494 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
495 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31
496 INT194513 Timp1 Negative_regulation of Cpox 1 0.00 0.9 1.31
497 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
498 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31
499 INT351245 Binding of TNC and OPN1LW 1 0.03 0.89 1.31
500 INT342979 HCL1 Positive_regulation of TRPV1 Positive_regulation of Localization of SFTPA1 1 0.00 0.54 1.31
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