G:114548

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Official Symbol NLRP3
Aliases AII, AVP, FCU, MWS, FCAS, CIAS1, NALP3, C1orf7, CLR1.1, PYPAF1, AGTAVPRL, FLJ95925
EntrezGene 114548
UniProt Coming Soon
Unique Molecular Interactions 31
Total Molecular Interactions 38
Total Single Events 136
Unique Interaction Partners 22

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to NLRP3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to NLRP3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to NLRP3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36743 NLRP3 Regulation of Mbp 1 0.01 0 0.43
2 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
3 INT191499 CMA1 Positive_regulation of NLRP3 1 0.02 0.42 0.3
4 INT191502 Binding of CMA1 and NLRP3 1 0.01 0.42 0.3
5 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28
6 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
7 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28
8 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28
9 INT219156 NLRP3 Positive_regulation of IL1B 1 0.01 1.03 0.27
10 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27
11 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27
12 INT219193 Nlrp3 Positive_regulation of Positive_regulation of NLRP3 1 0.24 1.03 0.26
13 INT191498 Binding of CTSG and NLRP3 1 0.07 0.37 0.25
14 INT191496 CTSG Positive_regulation of NLRP3 1 0.09 0.37 0.25
15 INT191536 Klk1c2 Positive_regulation of NLRP3 1 0.02 0.36 0.24
16 INT191537 Binding of Klk1c2 and NLRP3 1 0.02 0.36 0.24
17 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
18 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
19 INT23165 Binding of NLRP3 and BDNF-AS 1 0.01 0.83 0.16
20 INT23164 Negative_regulation of Binding of NLRP3 and BDNF-AS 1 0.01 0.83 0.16
21 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15
22 INT318306 Binding of DPEP1 and NLRP3 1 0.03 1.77 0.15
23 INT34431 NLRP3 Positive_regulation of Localization of POMC 1 0.41 0.31 0.14
24 INT219152 NLRP3 Positive_regulation of Positive_regulation of CASP1 1 0.02 0.83 0.1
25 INT233907 Positive_regulation of Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08
26 INT233906 Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08
27 INT188007 NLRP3 Regulation of Binding of TP53BP1 1 0.28 0.62 0.08
28 INT188006 NLRP3 Regulation of Gene_expression of TP53BP1 1 0.28 0.36 0.04
29 INT188005 NLRP3 Regulation of TP53BP1 1 0.34 0.3 0.04
30 INT345298 NLRP3 Positive_regulation of Localization of Edn1 1 0.01 0.94 0.03
31 INT270831 Positive_regulation of Panx1 Positive_regulation of NLRP3 1 0.18 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 114548. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 114548. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47
2 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57
3 INT10612 Localization of NLRP3 13 0.78 8.91 2.27
4 INT24453 Binding of NLRP3 18 0.48 13.7 1.93
5 INT23171 Negative_regulation of NLRP3 7 0.37 4.15 1.53
6 INT191527 Positive_regulation of Gene_expression of NLRP3 6 0.50 8.65 1.15
7 INT36742 Regulation of NLRP3 2 0.16 0 0.63
8 INT15981 Positive_regulation of Positive_regulation of NLRP3 2 0.44 1.02 0.62
9 INT244159 Transcription of NLRP3 3 0.64 5.61 0.39
10 INT219173 Negative_regulation of Gene_expression of NLRP3 1 0.19 1.02 0.26
11 INT219174 Negative_regulation of Positive_regulation of NLRP3 1 0.19 1.02 0.26
12 INT29590 Positive_regulation of Localization of NLRP3 3 0.49 0.51 0.23
13 INT191531 Regulation of Negative_regulation of NLRP3 1 0.08 0.32 0.19
14 INT244164 Positive_regulation of Transcription of NLRP3 1 0.43 0.13 0.05
15 INT48471 Regulation of Positive_regulation of NLRP3 1 0.07 0.36 0.05
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