G:11545

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Official Symbol Parp1
Aliases PARP, PPOL, Adprp, Adprt1, C80510, parp-1, sPARP-1, AI893648, 5830444G22Rik
EntrezGene 11545
UniProt Coming Soon
Unique Molecular Interactions 25
Total Molecular Interactions 39
Total Single Events 290
Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Parp1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Parp1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Parp1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
2 INT149684 Negative_regulation of Parp1 Positive_regulation of Oprm1 1 0.51 0 0.65
3 INT149681 Parp1 Regulation of Transcription of Oprm1 1 0.67 0 0.63
4 INT149682 Parp1 Negative_regulation of Oprm1 1 0.47 0 0.6
5 INT149683 Parp1 Negative_regulation of Transcription of Oprm1 1 0.47 0 0.58
6 INT341378 Positive_regulation of Ros1 Positive_regulation of Parp1 1 0.01 1.08 0.22
7 INT336503 Parp1 Positive_regulation of Tubgcp2 1 0.11 0.52 0.13
8 INT336504 Parp1 Positive_regulation of Mcpt3 1 0.11 0.52 0.13
9 INT336506 Parp1 Positive_regulation of Cxcl2 1 0.16 0.52 0.13
10 INT336505 Parp1 Positive_regulation of Mcpt1 1 0.14 0.52 0.13
11 INT253193 Ros1 Regulation of Parp1 1 0.01 0.57 0.05
12 INT322358 Binding of Parp1 and Casp3 1 0.05 1.08 0.04
13 INT261962 Binding of Parp1 and El4 1 0.19 1.33 0.03
14 INT250796 Tlr4 Positive_regulation of Parp1 1 0.14 1 0.03
15 INT225479 Binding of Parp1 and Acsl1 1 0.00 0 0
16 INT207817 Negative_regulation of Parp1 Positive_regulation of Atm 1 0.53 0.2 0
17 INT207815 Parp1 Negative_regulation of Phosphorylation of Atm 1 0.42 0.15 0
18 INT207816 Parp1 Regulation of Positive_regulation of Atm 1 0.51 0.21 0
19 INT308927 Gtf2i Positive_regulation of Gene_expression of Parp1 1 0.24 0 0
20 INT225614 Binding of XRCC5 and Parp1 1 0.09 0 0
21 INT341377 Gene_expression of Ros1 Positive_regulation of Parp1 1 0.01 1.03 0
22 INT322363 TNF Positive_regulation of Positive_regulation of Parp1 1 0.02 1.54 0
23 INT207813 Atm Regulation of Gene_expression of Parp1 1 0.44 0.31 0
24 INT207814 Negative_regulation of Parp1 Positive_regulation of Positive_regulation of Atm 1 0.53 0.08 0
25 INT207812 Binding of Parp1 and Atm 1 0.54 0.99 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 11545. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 11545. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84
2 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56
3 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02
4 INT131818 Binding of Parp1 14 0.46 8.74 1.76
5 INT63586 Regulation of Parp1 5 0.43 3.28 1.68
6 INT97053 Transcription of Parp1 3 0.66 2.04 1.43
7 INT175508 Protein_catabolism of Parp1 30 0.85 30 1.09
8 INT123816 Positive_regulation of Gene_expression of Parp1 9 0.50 6.64 1.04
9 INT147616 Negative_regulation of Positive_regulation of Parp1 3 0.43 2.53 0.84
10 INT123814 Positive_regulation of Positive_regulation of Parp1 9 0.50 9.32 0.57
11 INT109867 Negative_regulation of Negative_regulation of Parp1 2 0.42 3.37 0.49
12 INT186468 Positive_regulation of Protein_catabolism of Parp1 2 0.33 5.05 0.34
13 INT207809 Positive_regulation of Negative_regulation of Parp1 2 0.50 1.01 0.2
14 INT175532 Localization of Parp1 9 0.74 5.73 0.17
15 INT250795 Negative_regulation of Gene_expression of Parp1 4 0.41 5.01 0.15
16 INT199856 Negative_regulation of Protein_catabolism of Parp1 2 0.41 1.46 0.15
17 INT253175 Regulation of Positive_regulation of Parp1 2 0.52 0.97 0.08
18 INT175513 Positive_regulation of Localization of Parp1 2 0.23 2.23 0.07
19 INT253176 Regulation of Gene_expression of Parp1 2 0.23 0.61 0.05
20 INT175530 Regulation of Protein_catabolism of Parp1 1 0.09 1.36 0
21 INT207802 Regulation of Localization of Parp1 1 0.45 0.35 0
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