G:116554

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Official Symbol Mapk8
Aliases JNK
EntrezGene 116554
UniProt Coming Soon
Unique Molecular Interactions 58
Total Molecular Interactions 62
Total Single Events 551
Unique Interaction Partners 44

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Mapk8. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Mapk8. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Mapk8. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
2 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
3 INT98179 Aap Positive_regulation of Mapk8 1 0.01 0.75 0.74
4 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
5 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
6 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63
7 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
8 INT200913 Dio1 Positive_regulation of Mapk8 1 0.00 0 0.53
9 INT264476 Il1a Positive_regulation of Gene_expression of Mapk8 1 0.04 0 0.43
10 INT264475 Il1a Positive_regulation of Mapk8 1 0.04 0 0.43
11 INT179938 Negative_regulation of Mapk8 Negative_regulation of TNF 1 0.02 1.09 0.37
12 INT264480 Il1a Positive_regulation of Phosphorylation of Mapk8 1 0.04 0 0.37
13 INT309120 Edc4 Negative_regulation of Positive_regulation of Mapk8 1 0.01 1.03 0.36
14 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
15 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
16 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
17 INT167983 Mapk8 Negative_regulation of gr 1 0.02 0.5 0.31
18 INT159964 Tnf Positive_regulation of Phosphorylation of Mapk8 1 0.11 0.94 0.29
19 INT309122 Edc4 Positive_regulation of Phosphorylation of Mapk8 1 0.02 0.73 0.28
20 INT132368 Mapk8 Positive_regulation of Nfkb1 1 0.17 0.11 0.27
21 INT132369 Mapk8 Positive_regulation of Positive_regulation of Nfkb1 1 0.18 0.12 0.27
22 INT132366 Lgals1 Positive_regulation of Mapk8 1 0.38 0.13 0.27
23 INT132370 Mapk8 Positive_regulation of Ephb1 1 0.15 0.12 0.27
24 INT179928 Binding of Ephb1 and Mapk8 1 0.11 0.91 0.26
25 INT330053 Binding of Ros1 and Mapk8 1 0.02 0.88 0.24
26 INT95741 Creb1 Regulation of Mapk8 1 0.39 0 0.23
27 INT309124 Dlat Negative_regulation of Positive_regulation of Mapk8 1 0.02 0.27 0.22
28 INT309116 Edc4 Negative_regulation of Mapk8 1 0.01 0.43 0.22
29 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21
30 INT179935 Binding of Jun and Mapk8 1 0.04 0.61 0.19
31 INT179934 Mapk8 Regulation of Gene_expression of Mmp9 1 0.06 0.48 0.15
32 INT266531 Mapk8 Positive_regulation of Phosphorylation of Olr447 1 0.00 0 0.13
33 INT352467 Dusp1 Negative_regulation of Mapk8 1 0.02 0.23 0.12
34 INT348786 Tlr4 Positive_regulation of Mapk8 1 0.33 1.09 0.11
35 INT143648 Negative_regulation of Mapk8 Negative_regulation of Gene_expression of Fas 1 0.39 0.21 0.11
36 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
37 INT218676 Mapk8 Regulation of Mapk14 1 0.00 0.33 0.05
38 INT181571 Binding of Mapk8 and Mapk1 1 0.04 1.24 0.05
39 INT218703 Mapk8 Regulation of EPHB2 1 0.04 0.33 0.05
40 INT218667 Olr811 Regulation of Mapk8 1 0.00 0.33 0.05
41 INT274078 Binding of Mapk8 and Gmcl1 1 0.05 0.68 0.04
42 INT248703 Mapk8 Positive_regulation of Phosphorylation of Rxrb 1 0.01 0.25 0.04
43 INT179927 Litaf Positive_regulation of Mapk8 1 0.02 0.39 0.04
44 INT248698 Mapk8 Positive_regulation of Ppm1e 1 0.00 0.31 0.03
45 INT248706 Mapk8 Positive_regulation of Nr1i3 1 0.00 0.3 0.03
46 INT170910 Negative_regulation of Pcbd1 Positive_regulation of Positive_regulation of Mapk8 1 0.00 0.21 0.03
47 INT248699 Mapk8 Positive_regulation of Nr0b2 1 0.01 0.3 0.03
48 INT286026 Mapk8 Positive_regulation of Phosphorylation of Atf2 1 0.03 0.34 0
49 INT266532 Mapk8 Regulation of Olr447 1 0.00 0.1 0
50 INT205984 Mapk8 Positive_regulation of Map3k12 1 0.15 0.24 0
51 INT266555 Mapk8 Regulation of JUP 1 0.08 0.1 0
52 INT218674 Olr811 Positive_regulation of Phosphorylation of Mapk8 1 0.00 0.32 0
53 INT317956 Mapk8 Positive_regulation of Gene_expression of Tecr 1 0.07 0.08 0
54 INT317957 Mapk8 Negative_regulation of Gene_expression of Cldn18 1 0.06 0.08 0
55 INT205986 Mapk8 Positive_regulation of Trib3 1 0.02 0.73 0
56 INT274077 Binding of Tnfrsf1b and Positive_regulation of Mapk8 1 0.14 0.97 0
57 INT317958 Negative_regulation of Mapk8 Positive_regulation of Tecr 1 0.08 0.08 0
58 INT317963 Negative_regulation of Mapk8 Positive_regulation of Gene_expression of Tecr 1 0.08 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 116554. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 116554. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
2 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
3 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
4 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
5 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88
6 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97
7 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41
8 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58
9 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36
10 INT21569 Binding of Mapk8 8 0.48 5.55 3.44
11 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2
12 INT95735 Regulation of Phosphorylation of Mapk8 7 0.50 1.88 2.69
13 INT95739 Negative_regulation of Phosphorylation of Mapk8 11 0.42 6.77 2.61
14 INT156270 Regulation of Positive_regulation of Mapk8 3 0.41 2.31 2.08
15 INT152696 Negative_regulation of Negative_regulation of Mapk8 1 0.32 0.35 2
16 INT164864 Positive_regulation of Negative_regulation of Mapk8 1 0.31 1.33 1.82
17 INT200900 Localization of Mapk8 9 0.40 5.76 0.84
18 INT164489 Regulation of Gene_expression of Mapk8 2 0.44 0.65 0.74
19 INT301056 Transcription of Mapk8 1 0.06 1.22 0.45
20 INT261486 Protein_catabolism of Mapk8 1 0.27 0 0
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