G:12043

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Official Symbol Bcl2
Aliases Bcl-2, AW986256, C430015F12Rik, D630044D05Rik, D830018M01Rik
EntrezGene 12043
UniProt Coming Soon
Unique Molecular Interactions 67
Total Molecular Interactions 109
Total Single Events 888
Unique Interaction Partners 47

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Bcl2. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Bcl2. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Bcl2. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
2 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
3 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
4 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
5 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
6 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
7 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
8 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
9 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
10 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
11 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
12 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
13 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
14 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
15 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
16 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
17 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
18 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
19 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
20 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
21 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07
22 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04
23 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04
24 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
25 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04
26 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
27 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04
28 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
29 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03
30 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
31 INT172894 Negative_regulation of Lox Negative_regulation of Gene_expression of Bcl2 1 0.03 1.12 0.03
32 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03
33 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
34 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0
35 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
36 INT295047 Binding of Bcl2 and Nr4a1 1 0.04 0.96 0
37 INT254089 EPO Regulation of Gene_expression of Bcl2 1 0.03 0.63 0
38 INT295046 Bcl2 Regulation of Gene_expression of Nr4a1 1 0.02 0.92 0
39 INT253474 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Bcl2 1 0.04 1.27 0
40 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
41 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
42 INT221240 Akt1 Positive_regulation of Phosphorylation of Bcl2 1 0.00 0.89 0
43 INT191062 Esr1 Regulation of Gene_expression of Bcl2 1 0.12 0.73 0
44 INT267255 Bcl2 Positive_regulation of Gene_expression of Ptprj 1 0.04 0.63 0
45 INT191061 Akt1 Positive_regulation of Bcl2 1 0.41 0.33 0
46 INT283003 Igkv1-131 Regulation of Binding of Bcl2 1 0.06 0 0
47 INT283009 Binding of Bcl2 and Pdss2 1 0.03 0.56 0
48 INT202507 Nfasc Positive_regulation of Gene_expression of Bcl2 1 0.10 0.7 0
49 INT283000 Negative_regulation of Binding of Bcl2 and Becn1 1 0.03 0.71 0
50 INT331231 Binding of Bcl2 and Mapk8 1 0.01 0.77 0
51 INT283011 Binding of Bcl2 and Igkv1-131 1 0.05 0.8 0
52 INT191065 Binding of Bcl2 and Negative_regulation of Phosphorylation of Akt1 1 0.22 1.02 0
53 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0
54 INT202503 Gtf3a Positive_regulation of Positive_regulation of Bcl2 1 0.02 0.35 0
55 INT327403 Bcl2 Positive_regulation of Localization of Mmp2 1 0.19 0.93 0
56 INT283010 Regulation of Binding of Bcl2 and Becn1 1 0.03 1.45 0
57 INT305541 Binding of Bcl2 and Trp53 1 0.05 0.9 0
58 INT282997 Binding of Bcl2 and Om 1 0.00 0.45 0
59 INT283014 Becn1 Regulation of Bcl2 1 0.03 0.88 0
60 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0
61 INT352150 Ift88 Negative_regulation of Bcl2 1 0.00 0.19 0
62 INT282998 Binding of Bcl2 and Bbc3 1 0.00 0.43 0
63 INT242479 Negative_regulation of Ciapin1 Negative_regulation of Bcl2 1 0.14 1.28 0
64 INT333687 Trp53 Positive_regulation of Localization of Bcl2 1 0.45 1.24 0
65 INT254694 Positive_regulation of Map2k2 Regulation of Bcl2 1 0.02 0.89 0
66 INT267254 Binding of Bcl2 and Hspa9 1 0.04 0.54 0
67 INT189993 Binding of Bcl2 and Ptger2 1 0.00 1.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 12043. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 12043. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
2 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
3 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
4 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
5 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
6 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
7 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
8 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
9 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
10 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
11 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
12 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
13 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
14 INT108563 Negative_regulation of Regulation of Bcl2 1 0.32 0.74 0.22
15 INT220426 Regulation of Negative_regulation of Bcl2 1 0.05 0.81 0.18
16 INT110957 Positive_regulation of Positive_regulation of Bcl2 3 0.35 2.3 0.13
17 INT179038 Positive_regulation of Regulation of Bcl2 1 0.39 3.49 0.12
18 INT221673 Negative_regulation of Protein_catabolism of Bcl2 1 0.11 0.15 0.03
19 INT123521 Phosphorylation of Bcl2 8 0.81 5 0
20 INT191056 Negative_regulation of Binding of Bcl2 2 0.37 0.48 0
21 INT204053 Negative_regulation of Transcription of Bcl2 1 0.04 0.86 0
22 INT282976 Positive_regulation of Binding of Bcl2 1 0.29 0.76 0
23 INT191048 Positive_regulation of Phosphorylation of Bcl2 1 0.69 0.44 0
24 INT341935 Regulation of Phosphorylation of Bcl2 1 0.04 0 0
25 INT282971 Positive_regulation of Localization of Bcl2 1 0.29 0 0
26 INT191049 Regulation of Binding of Bcl2 1 0.39 0.52 0
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